GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
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TC-N 22A
CAS:1314140-00-5
TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can …
Formula:
C14H13N5S
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
283.35
Ref: TM-T23440
| 1mg | 119.00 € | ||
| 5mg | 246.00 € | ||
| 10mg | 302.00 € | ||
| 25mg | 509.00 € | ||
| 50mg | 734.00 € | ||
| 100mg | 1,009.00 € |
Estimated delivery in United States, on Tuesday 1 Apr 2025
LSN2463359
CAS:1401031-52-4
LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.
Formula:
C16H15N3O
Purity:
99.36%
Color and Shape:
Solid
Molecular weight:
265.31
Ref: TM-T27854
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 166.00 € | ||
| 50mg | 253.00 € | ||
| 100mg | 373.00 € | ||
| 200mg | 530.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 1 Apr 2025
LYPLAL1-IN-1
CAS:1966129-74-7
LYPLAL1-IN-1 is a selective covalent small-molecule inhibitor of Lysophospholipase-like 1 (IC50: 0.006 μM). LYPLAL1-IN-1 also …
Formula:
C29H29N7O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
539.59
Ref: TM-T15823
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Tuesday 1 Apr 2025
DMeOB
CAS:40252-74-2
DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and is used in the …
Formula:
C16H16N2O2
Purity:
98.34%
Color and Shape:
Solid
Molecular weight:
268.31
Ref: TM-T22736
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 198.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 461.00 € | ||
| 500mg | 995.00 € | ||
| 1mL*10mM (DMSO) | 84.00 € |
Estimated delivery in United States, on Tuesday 1 Apr 2025
CPPHA
CAS:693288-97-0
CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in …
Formula:
C22H15ClN2O4
Purity:
99.61%
Color and Shape:
Solid
Molecular weight:
406.82
Ref: TM-T10881
| 5mg | 35.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Tuesday 1 Apr 2025
Valiglurax
CAS:1976050-09-5
Valiglurax (VU2957), potent mGlu4 PAM, crosses blood-brain barrier, orally available; promising for Parkinson's treatment.
Formula:
C16H10F3N5
Purity:
97.38%
Color and Shape:
Solid
Molecular weight:
329.28
Ref: TM-T35028
| 10mg | 49.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 160.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 1 Apr 2025
ML289
CAS:1382481-79-9
ML289 is a potent CNS-penetrant mGlu3 modulator with IC50 of 0.66 μM, >15-fold selectivity over …
Formula:
C22H23NO3
Purity:
99.09%
Color and Shape:
Solid
Molecular weight:
349.42
Ref: TM-T23000
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 216.00 € | ||
| 100mg | 326.00 € | ||
| 200mg | 453.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Tuesday 1 Apr 2025
MFZ 10-7 hydrochloride
CAS:1779796-36-9
MFZ 10-7 hydrochloride is a highly potent and selective negative allosteric modulator of mGluR5 NAM
Formula:
C15H10ClFN2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
272.71
Ref: TM-T12025
| 25mg | 1,410.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,329.00 € |
Estimated delivery in United States, on Tuesday 1 Apr 2025
VU6004909
CAS:1860797-76-7
VU6004909 is an mGlu5 receptor orthosteric modulator that reverses MK801-induced increased cortical activity and cognitive …
Formula:
C21H15FN2O4
Purity:
96.68% - 98.44%
Color and Shape:
Liquid
Molecular weight:
378.35
Ref: TM-T79784
| 1mg | 47.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 135.00 € | ||
| 25mg | 258.00 € | ||
| 50mg | 412.00 € | ||
| 100mg | 648.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Philanthotoxin 74 dihydrochloride
CAS:1227301-51-0
Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM …
Formula:
C24H44Cl2N4O3
Purity:
98.6%
Color and Shape:
Solid
Molecular weight:
507.54
Ref: TM-T16524
| 1mg | 51.00 € | ||
| 5mg | 144.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 188.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Pomaglumetad methionil hydrochloride
CAS:635318-26-2
LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.
Formula:
C12H19ClN2O7S2
Purity:
99.01%
Color and Shape:
Liquid
Molecular weight:
402.87
Ref: TM-T61972
| 1mg | 197.00 € | ||
| 5mg | 502.00 € | ||
| 10mg | 723.00 € | ||
| 25mg | 1,103.00 € | ||
| 50mg | 1,504.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Biphenylindanone A
CAS:866823-73-6
Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological …
Formula:
C30H30O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
454.56
Ref: TM-T14615
| 5mg | 252.00 € | ||
| 10mg | 437.00 € | ||
| 25mg | 1,006.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
FPTQ
CAS:864863-72-9
FPTQ is a highly effective antagonist of mGluR 1, displaying IC50 values of 6 nM …
Formula:
C17H12FN5
Purity:
99.68% - 99.88%
Color and Shape:
Liquid
Molecular weight:
305.31
Ref: TM-T5509
| 1mg | 50.00 € | ||
| 2mg | 73.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 158.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 412.00 € | ||
| 100mg | 546.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
AMPA receptor modulator-2
CAS:2034181-36-5
AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent …
Formula:
C15H6F6N4OS
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
404.29
Ref: TM-T37734
| 1mg | 121.00 € | ||
| 5mg | 292.00 € | ||
| 10mg | 384.00 € | ||
| 25mg | 615.00 € | ||
| 50mg | 884.00 € | ||
| 100mg | 1,225.00 € | ||
| 1mL*10mM (DMSO) | 324.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
VU6005649
CAS:2137047-43-7
VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM …
Formula:
C16H12F5N3O
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
357.28
Ref: TM-T13321
| 5mg | 41.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 105.00 € | ||
| 50mg | 170.00 € | ||
| 100mg | 258.00 € | ||
| 200mg | 367.00 € | ||
| 1mL*10mM (DMSO) | 44.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
VU6012962
CAS:2313526-86-0
VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: …
Formula:
C21H19F3N4O4
Purity:
97% - 98.31%
Color and Shape:
Solid
Molecular weight:
448.4
Ref: TM-T13323
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 233.00 € | ||
| 50mg | 418.00 € | ||
| 100mg | 611.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
cis-PDA
CAS:46026-75-9
cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, …
Formula:
C7H11NO4
Purity:
≥98%
Color and Shape:
White Solid
Molecular weight:
173.17
Ref: TM-T20571
| 10mg | 34.00 € | ||
| 25mg | 52.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 15 Apr 2025
JNJ-46281222
CAS:1254980-38-5
JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.
Formula:
C23H25F3N4
Color and Shape:
Solid
Molecular weight:
414.47
Ref: TM-T15618
| 25mg | 1,327.00 € | ||
| 50mg | 1,741.00 € | ||
| 100mg | 2,986.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Licostinel
CAS:153504-81-5
Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia.
Formula:
C8H3Cl2N3O4
Purity:
98.02%
Color and Shape:
Solid
Molecular weight:
276.03
Ref: TM-T27828
| 5mg | 59.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 278.00 € | ||
| 100mg | 413.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
L-AP4
CAS:23052-81-5
L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, …
Formula:
C4H10NO5P
Purity:
98%
Color and Shape:
White To Off-White Crystalline Powder
Molecular weight:
183.1
Ref: TM-T15692
| 1mg | 138.00 € | ||
| 5mg | 231.00 € | ||
| 10mg | 394.00 € | ||
| 50mg | 1,632.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
