AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 643 products of "AChR"
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Clidinium bromide
CAS:Clidinium bromide (Ro 2-3773), a synthetic anticholinergic, treats peptic ulcers and alleviates abdominal cramps and IBS symptoms.Formula:C22H26BrNO3Purity:98.89% - 99.86%Color and Shape:White Crystalline SolidMolecular weight:432.35Procainamide hydrochloride
CAS:Procainamide Hydrochloride (Procapan) is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analogFormula:C13H21N3O·HClPurity:99.83% - 99.97%Color and Shape:White To Slightly Yellow PowderMolecular weight:271.79Pirenzepine dihydrochloride
CAS:Pirenzepine dihydrochloride (LS519) is a selective M1 muscarinic receptor antagonist, inhibiting gastric secretion.Formula:C19H21N5O2·2HClPurity:99.48% - 99.62%Color and Shape:White PowderMolecular weight:424.32Bambuterol hydrochloride
CAS:Bambuterol hydrochloride (KWD-2183 hydrochloride) , a long-acting beta-adrenoceptor agonist, is utilized for the treating of asthma.Formula:C18H30ClN3O5Purity:99.53% - 99.61%Color and Shape:White SolidMolecular weight:403.91Promethazine hydrochloride
CAS:Promethazine HCl: First-gen antihistamine, H1 and mACh blocker, affects 5-HT2A/C, D2, α1 receptors.Formula:C17H20N2S·HClPurity:99.85%Color and Shape:Crystals In Water Has A Ph Of 3 5-5 0 (Ntp 1992)Molecular weight:320.88Clevidipine
CAS:Clevidipine (Clevidipine butyrate) is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for bloodFormula:C21H23Cl2NO6Purity:99.40%Color and Shape:PowderMolecular weight:456.32(Rac)-ABT-202 dihydrochloride
CAS:(Rac)-ABT-202 dihydrochloride is a racemate of ABT-202. ABT-202 is an nicotinic acetylcholine receptors (nAChRs) agonist and can be used as an analgesic.Formula:C9H15Cl2N3Purity:97.4%Color and Shape:SolidMolecular weight:236.142Nebracetam hydrochloride
CAS:Nebracetam HCl (WEB 1881 FU) is an M1-muscarinic agonist nootropic, increasing intracellular Ca2+ with an EC50 of 1.59 mM.Formula:C12H17ClN2OPurity:99.23%Color and Shape:SolidMolecular weight:240.729(Rac)-Sabcomeline HCl
CAS:Sabcomeline HCl is an M1 receptor agonist that can be used to study Alzheimer's disease.Formula:C10H16ClN3OPurity:99.58%Color and Shape:SoildMolecular weight:229.71Pyrantel pamoate
CAS:Pyrantel pamoate (Pyrantel embonate) is a depolarizing neuromuscular blocking agent.Formula:C34H30N2O6SPurity:99.71%Molecular weight:594.69Carbachol
CAS:Carbachol (Carbamoylcholine chloride), an analog of acetylcholine, serves as a valuable tool in the investigation of various physiological responses mediated by nicotinic (nAChR) and muscarinic (mAChR) acetylcholine receptors. These responses include smooth muscle contraction, gut motility, and neuronal signaling. Known for its agonistic properties, Carbachol activates both nAChR and mAChR, with reported Ki values ranging from 10 to 10,000 nM for different receptor types and experimental preparations.Formula:C6H15ClN2O2Purity:>99.99%Color and Shape:SolidMolecular weight:182.65TAK-071
CAS:TAK-071 is a potent, novel and highly selective modulator of muscarinic acetylcholine receptor 1 (M1R) positive allosteric(EC50 : 520 nM).
Formula:C24H24FN3O3Purity:98.02%Color and Shape:SolidMolecular weight:421.46Acetamiprid
CAS:Acetamiprid: nAChR agonist, global neonicotinoid insecticide linked to neuromuscular/reproductive issues.Formula:C10H11ClN4Purity:99.66%Color and Shape:White PowderMolecular weight:222.67Adiphenine hydrochloride
CAS:Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.Formula:C20H25NO2·HClPurity:97.76% - 99.53%Color and Shape:White Or Almost White PowderMolecular weight:347.88Rocuronium bromide
CAS:Rocuronium bromide (ORG 9426) is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker, which is used to provide skeletal muscle relaxation.Formula:C32H53BrN2O4Purity:99.77% - >99.99%Color and Shape:White Or Off-White PowderMolecular weight:609.68Benzethonium chloride
CAS:Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.Formula:C27H42ClNO2Purity:99.91%Color and Shape:White To Off-White Solid Solid Particulate/PowderMolecular weight:448.09Dicyclomine hydrochloride
CAS:Dicyclomine hydrochloride is a muscarinic antagonist used as an antispasmodic and in urinary incontinence.Formula:C19H36ClNO2Purity:99.81%Color and Shape:SolidMolecular weight:345.95Lysipressin acetate(50-57-7(fb_acetate))
CAS:Lysipressin acetate (50-57-7), triggers rabbit bladder contraction & activates adenylate cyclase, is an antidiuretic in pigs & marsupials.
Formula:C48H69N13O14S2Purity:98.08%Color and Shape:SolidMolecular weight:1116.28VU 0365114
CAS:VU 0365114 is a positive allosteric modulator of mAChR M5 and increases ACh-induced calcium mobilization(EC50: 2.7 μM).Formula:C22H14F3NO3Purity:99.86%Color and Shape:SolidMolecular weight:397.35Ref: TM-T13325
2mg35.00€5mg55.00€10mg78.00€25mg130.00€50mg212.00€100mg318.00€200mg444.00€1mL*10mM (DMSO)62.00€Fesoterodine fumarate
CAS:Fesoterodine fumarate (Toviaz) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties.Formula:C26H37NO3·C4H4O4Purity:99.16%Color and Shape:White SolidMolecular weight:527.65Ref: TM-T1475
2mg34.00€5mg50.00€10mg71.00€25mg100.00€50mg137.00€100mg205.00€500mg396.00€1mL*10mM (DMSO)54.00€Carbetapentane citrate
CAS:Carbetapentane citrate (Pentoxyverine citrate) , an antitussive (cough suppressant), is frequently used for a cough related to illnesses like the common cold.Formula:C20H31NO3·C6H8O7Purity:99.46%Color and Shape:White To Off-White SolidMolecular weight:525.59Lupanine hydrochloride
CAS:Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.Formula:C15H25ClN2OColor and Shape:SolidMolecular weight:284.83β2AR/M-receptor agonist-1
CAS:β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor andFormula:C43H56BrN3O7Color and Shape:SolidMolecular weight:806.82nAChR modulator-1
CAS:nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .Formula:C12H8ClN3O2Color and Shape:SolidMolecular weight:261.66nAChR modulator-2
CAS:nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .Formula:C12H8ClN3O2Color and Shape:SolidMolecular weight:261.66Perindoprilat
CAS:Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.Formula:C17H28N2O5Purity:99.21%Color and Shape:SolidMolecular weight:340.41Navafenterol saccharinate
CAS:AZD-8871 saccharinate is a dual-acting bronchodilator which may be useful in the treatment of Chronic Obstructive Pulmonary Disease (COPD).Formula:C45H47N7O9S3Color and Shape:SolidMolecular weight:926.09Irsogladine maleate
CAS:Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C9H7Cl2N5Color and Shape:SolidMolecular weight:256.09Epiboxidine
CAS:Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.Formula:C10H14N2OColor and Shape:SolidMolecular weight:178.23Methylatropine (nitrate)
CAS:Methylatropine: Muscarinic antagonist, <0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.Formula:C18H26N2O6Color and Shape:SolidMolecular weight:366.414Atracurium
CAS:Atracurium (BW-33A) is a competitive AChR antagonist and non-depolarizing muscle relaxant that may cause bronchoconstriction.Formula:C53H72N2O122Color and Shape:SolidMolecular weight:929.14(Rac)-5-Hydroxymethyl Tolterodine hydrochloride
CAS:(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.
Formula:C22H32ClNO2Color and Shape:SolidMolecular weight:377.95(R)-Dinotefuran
CAS:(R)-Dinotefuran, a neonicotinoid, is 1.7-2.4x more effective against pests like Aphis gossypii and safer for bees.Formula:C7H14N4O3Color and Shape:SolidMolecular weight:202.21DSPE-PEG1000-RVG29
DSPE-PEG1000-RVG29 is a PEG compound composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 can specifically bind to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and cross the BBB.Color and Shape:Odour SolidMuscarine
CAS:Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.Formula:C9H20NO2Purity:98%Color and Shape:SolidMolecular weight:174.26(rel)-Asperparaline A
CAS:Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.
Formula:C20H29N3O3Color and Shape:SolidMolecular weight:359.47Lobeline sulfate
CAS:Lobeline sulfate, an alkaloid like nicotine, aids in smoking cessation, insomnia, and respiratory issues. Less potent on nicotinic receptors.Formula:C22H29NO6SPurity:98%Color and Shape:White PowderMolecular weight:435.54MK-0969
CAS:MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.Formula:C24H30F2N4O2Color and Shape:SolidMolecular weight:444.52TMPH
CAS:TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.Formula:C16H31NO2Purity:99.78%Color and Shape:SoildMolecular weight:269.42Ref: TM-T60080
2mg35.00€5mg55.00€10mg84.00€25mg133.00€50mg205.00€100mg301.00€200mg425.00€1mL*10mM (DMSO)54.00€8-Aminoadenine
CAS:8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.Formula:C5H6N6Purity:99.82%Color and Shape:SolidMolecular weight:150.14TC-2559 difumarate
CAS:TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.Formula:C20H26N2O9Color and Shape:SolidMolecular weight:438.43Heliosupine N-oxide
Heliosupine N-oxide is a useful organic compound for research related to life sciences and the catalog number is T125058.Formula:C20H31NO8Color and Shape:SolidMolecular weight:413.467M3/PDE4 modulator-1
M3/PDE4 Modulator-1 (compound 10f) serves as a bifunctional entity functioning both as an M3 mAChR antagonist and a PDE4 inhibitor.Formula:C38H41Cl2N3O8SColor and Shape:SolidMolecular weight:770.72Octamylamine
CAS:Octamylamine is a bioactive chemical.Formula:C13H29NColor and Shape:SolidMolecular weight:199.3761nAChR agonist CMPI hydrochloride
CAS:CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.Formula:C18H20Cl2N4OColor and Shape:SolidMolecular weight:379.29Dicloromezotiaz
CAS:Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.Formula:C19H12Cl3N3O2SColor and Shape:SolidMolecular weight:452.74rac-Desethyl Oxybutynin (hydrochloride)
CAS:rac-Desethyl oxybutynin, active oxybutynin metabolite, binds to mAChRs; K_i values 3.12-16 nM; lowers rat micturition pressure.Formula:C20H28ClNO3Color and Shape:SolidMolecular weight:365.89α-Bungarotoxin
CAS:Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs).Formula:C338H529N97O105S11Purity:98%Color and Shape:SolidMolecular weight:7984.14AC1-IN-1
CAS:AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).
Formula:C18H18FN5O2Purity:99.89%Color and Shape:SolidMolecular weight:355.37(R)-(+)-Anatabine
CAS:(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.Formula:C10H12N2Purity:98%Color and Shape:SolidMolecular weight:160.22
