Proteasome
Proteasome inhibitors are compounds that inhibit the proteasome, a large protein complex responsible for degrading unwanted or damaged proteins within the cell. Inhibition of the proteasome leads to the accumulation of proteins, which can induce cell cycle arrest and apoptosis, particularly in rapidly dividing cells like cancer cells. Proteasome inhibitors are crucial in cancer research and therapy, especially in the treatment of multiple myeloma and other hematologic malignancies. At CymitQuimica, we offer proteasome inhibitors to support your research in oncology, cell biology, and drug development.
Found 94 products of "Proteasome"
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Alloxan monohydrate
CAS:<p>Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.</p>Formula:C4H4N2O5Purity:99.01% - 99.42%Color and Shape:Off-White To Beige-Yellowish Crystalline PowderMolecular weight:160.09ARV-471
CAS:<p>ARV-471 (Vepdegestrant) is a orally active Cereblon -based estrogen receptor (ER) PROTAC degrader. ARV-471 is developed for the research of breast cancer.</p>Formula:C45H49N5O4Purity:97.15% - >99.99%Color and Shape:SolidMolecular weight:723.9Omarigliptin
CAS:<p>Omarigliptin is a potent and selective oral dipeptidyl peptidase 4 (DPP4) inhibitor with IC50 value of 1.6 nM. Cost-effective and quality-assured.</p>Formula:C17H20F2N4O3SPurity:99.68% - 99.77%Color and Shape:SolidMolecular weight:398.43Calpeptin
CAS:<p>Calpeptin is a potent, cell-permeable calpain inhibitor.</p>Formula:C20H30N2O4Purity:97.06% - 98.33%Color and Shape:White To Off-White PowderMolecular weight:362.46Talabostat mesylate
CAS:<p>Talabostat mesylate (PT100): Oral DPP4 inhibitor, IC50 0.18 nM, targets tumor-linked proteins, boosts hematopoiesis.</p>Formula:C10H23BN2O6SPurity:98% - 99.91%Color and Shape:SolidMolecular weight:310.18PI-1840
CAS:<p>PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.</p>Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.474'-Hydroxychalcone
CAS:<p>4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity</p>Formula:C15H12O2Purity:99.86% - 99.87%Color and Shape:Yellow-Cream PowderMolecular weight:224.25ONX-0914
CAS:<p>ONX-0914 (PR-957) is an effective and specific immunoproteasome inhibitor, which has minimal cross-reactivity for the constitutive proteasome.</p>Formula:C31H40N4O7Purity:98.24% - 99.31%Color and Shape:SolidMolecular weight:580.67Bortezomib
CAS:<p>Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.</p>Formula:C19H25BN4O4Purity:97.79% - >99.99%Color and Shape:Yellow SolidMolecular weight:384.24Epoxomicin
CAS:<p>Epoxomicin, a selective proteasome inhibitor, chiefly blocks CH-L activity, mildly affecting T-L and PGPH at lower rates.</p>Formula:C28H50N4O7Purity:98.65% - 98.86%Color and Shape:White To Off-White SolidMolecular weight:554.72Carfilzomib
CAS:<p>Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.</p>Formula:C40H57N5O7Purity:99.6% - 99.84%Color and Shape:SolidMolecular weight:719.91MDL-28170
CAS:<p>MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.</p>Formula:C22H26N2O4Purity:95.06%Color and Shape:SolidMolecular weight:382.45ISOGINKGETIN
CAS:<p>ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.</p>Formula:C32H22O10Purity:98% - 99.72%Color and Shape:SolidMolecular weight:566.51Oprozomib
CAS:<p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>Formula:C25H32N4O7SPurity:98% - 99.87%Color and Shape:SolidMolecular weight:532.61UAMC00039 dihydrochloride
CAS:<p>UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 of 0.48 nM.</p>Formula:C16H26Cl3N3OPurity:>99.99%Color and Shape:SolidMolecular weight:382.76MUN57694
CAS:<p>MUN57694 is an inhibitor of 26S proteasome.</p>Formula:C23H25N3O4Purity:99%Color and Shape:SolidMolecular weight:407.46Saxagliptin
CAS:<p>Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.</p>Formula:C18H25N3O2Purity:99.17% - 99.95%Color and Shape:SolidMolecular weight:315.41Tomatine
CAS:<p>Tomatine (lycopersicin) is an antiproliferatve agent of breast adenocarcinoma cells.</p>Formula:C50H83NO21Purity:98.42% - 99.94%Color and Shape:White To Light YellowMolecular weight:1034.19MG-101
CAS:<p>MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.</p>Formula:C20H37N3O4Purity:98% - ≥98%Color and Shape:SolidMolecular weight:383.53Bortezomib-pinanediol
CAS:<p>Bortezomib-pinanediol is a proteasome inhibitor. is a prodrug of Bortezomib.</p>Formula:C29H39BN4O4Purity:97.5%Color and Shape:Yellow SolidMolecular weight:518.46
