Proteasome
Proteasome inhibitors are compounds that inhibit the proteasome, a large protein complex responsible for degrading unwanted or damaged proteins within the cell. Inhibition of the proteasome leads to the accumulation of proteins, which can induce cell cycle arrest and apoptosis, particularly in rapidly dividing cells like cancer cells. Proteasome inhibitors are crucial in cancer research and therapy, especially in the treatment of multiple myeloma and other hematologic malignancies. At CymitQuimica, we offer proteasome inhibitors to support your research in oncology, cell biology, and drug development.
Found 91 products for "Proteasome".
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Delanzomib
CAS:Delanzomib (CEP-18770) is an oral proteasome inhibitor with an IC50 of 3.8 nM, targeting chymotrypsin-like activity with minimal effect on other activities.Formula:C21H28BN3O5Purity:95.52% - 99.46%Color and Shape:SolidMolecular weight:413.28Ref: TM-T6027
1mg43.00€1mL*10mM (DMSO)89.00€5mg92.00€10mg133.00€25mg260.00€50mg416.00€100mg625.00€200mg868.00€MDL-28170
CAS:MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.Formula:C22H26N2O4Purity:95.06%Color and Shape:SolidMolecular weight:382.45Ref: TM-T2470
1mg34.00€2mg49.00€5mg71.00€1mL*10mM (DMSO)75.00€10mg90.00€25mg128.00€50mg167.00€100mg284.00€ISOGINKGETIN
CAS:ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.Formula:C32H22O10Purity:98% - 99.75%Color and Shape:Yellow SolidMolecular weight:566.51Oprozomib
CAS:Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.Formula:C25H32N4O7SPurity:98% - 99.87%Color and Shape:White SolidMolecular weight:532.61UAMC00039 dihydrochloride
CAS:UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 of 0.48 nM.Formula:C16H26Cl3N3OPurity:99.70%Color and Shape:SolidMolecular weight:382.76(R)-MG-132
CAS:(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.Formula:C26H41N3O5Purity:99.90%Color and Shape:SolidMolecular weight:475.62Ref: TM-T12628
2mg38.00€5mg57.00€1mL*10mM (DMSO)71.00€10mg79.00€25mg120.00€50mg177.00€100mg268.00€200mg398.00€Epoxomicin
CAS:Epoxomicin, a selective proteasome inhibitor, chiefly blocks CH-L activity, mildly affecting T-L and PGPH at lower rates.Formula:C28H50N4O7Purity:98.65% - 98.86%Color and Shape:SolidMolecular weight:554.72Ref: TM-T6830
1mg118.00€5mg295.00€1mL*10mM (DMSO)355.00€10mg475.00€25mg773.00€50mg1,071.00€100mg1,423.00€500mg2,862.00€Carfilzomib
CAS:Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.Formula:C40H57N5O7Purity:99.6% - 99.84%Color and Shape:White SolidMolecular weight:719.91MG-132
CAS:MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!Formula:C26H41N3O5Purity:95% - 99.99%Color and Shape:SolidMolecular weight:475.62Ref: TM-T2154
1mL*10mM (DMSO)44.00€10mg46.00€25mg84.00€50mg137.00€100mg205.00€200mg356.00€500mg447.00€MUN57694
CAS:MUN57694 is an inhibitor of 26S proteasome.Formula:C23H25N3O4Purity:99%Color and Shape:White SolidMolecular weight:407.46Ref: TM-T9090
2mg35.00€5mg52.00€1mL*10mM (DMSO)64.00€10mg86.00€25mg145.00€50mg210.00€100mg296.00€200mg414.00€Ixazomib citrate
CAS:Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).Formula:C20H23BCl2N2O9Purity:98.37% - >99.99%Color and Shape:White SolidMolecular weight:517.12Tomatine
CAS:Tomatine (lycopersicin) is an antiproliferatve agent of breast adenocarcinoma cells.Formula:C50H83NO21Purity:98.42% - 99.93%Color and Shape:SolidMolecular weight:1034.19MG-101
CAS:MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.Formula:C20H37N3O4Purity:97.02% - 98%Color and Shape:SolidMolecular weight:383.53Bortezomib-pinanediol
CAS:Bortezomib-pinanediol is a proteasome inhibitor. is a prodrug of Bortezomib.Formula:C29H39BN4O4Purity:97.5%Color and Shape:SolidMolecular weight:518.46DD1
CAS:DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.Formula:C16H14N2O3Purity:99.57%Color and Shape:SolidMolecular weight:282.29Calpeptin
CAS:Calpeptin is a potent, cell-permeable calpain inhibitor.Formula:C20H30N2O4Purity:97.06% - 98.33%Color and Shape:SolidMolecular weight:362.46Tripterin
CAS:Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.Formula:C29H38O4Purity:98.56% - 99.8%Color and Shape:Orange SolidMolecular weight:450.61PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.47Proteasome inhibitor IX
CAS:Proteasome inhibitor IX (PS-IX) is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM).Formula:C20H21B2NO5Purity:99.77%Color and Shape:SolidMolecular weight:377.01Vepdegestrant
CAS:Vepdegestrant(ARV-471 ) is a orally active Cereblon -based estrogen receptor (ER) PROTAC degrader. ARV-471 is developed for the research of breast cancer.Formula:C45H49N5O4Purity:97.15% - >99.99%Color and Shape:SolidMolecular weight:723.9
