Proteasome
Proteasome inhibitors are compounds that inhibit the proteasome, a large protein complex responsible for degrading unwanted or damaged proteins within the cell. Inhibition of the proteasome leads to the accumulation of proteins, which can induce cell cycle arrest and apoptosis, particularly in rapidly dividing cells like cancer cells. Proteasome inhibitors are crucial in cancer research and therapy, especially in the treatment of multiple myeloma and other hematologic malignancies. At CymitQuimica, we offer proteasome inhibitors to support your research in oncology, cell biology, and drug development.
Found 84 products for "Proteasome".
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Vepdegestrant
CAS:Vepdegestrant(ARV-471 ) is a orally active Cereblon -based estrogen receptor (ER) PROTAC degrader. ARV-471 is developed for the research of breast cancer.Formula:C45H49N5O4Purity:97.15% - >99.99%Color and Shape:SolidMolecular weight:723.9Calpeptin
CAS:Calpeptin is a potent, cell-permeable calpain inhibitor.Formula:C20H30N2O4Purity:97.06% - 98.33%Color and Shape:SolidMolecular weight:362.46PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.474'-Hydroxychalcone
CAS:4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activityFormula:C15H12O2Purity:99.86% - 99.87%Color and Shape:Yellow-Cream PowderMolecular weight:224.25ONX-0914
CAS:ONX-0914 (PR-957) is an effective and specific immunoproteasome inhibitor, which has minimal cross-reactivity for the constitutive proteasome.Formula:C31H40N4O7Purity:98.24% - 99.31%Color and Shape:SolidMolecular weight:580.67Bortezomib
CAS:Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Formula:C19H25BN4O4Purity:97.79% - >99.99%Color and Shape:White SolidMolecular weight:384.24Ref: TM-T2399
5mg50.00€1mL*10mM (DMSO)50.00€10mg60.00€25mg75.00€50mg92.00€100mg137.00€200mg213.00€500mg353.00€Epoxomicin
CAS:Epoxomicin, a selective proteasome inhibitor, chiefly blocks CH-L activity, mildly affecting T-L and PGPH at lower rates.Formula:C28H50N4O7Purity:98.65% - 98.86%Color and Shape:SolidMolecular weight:554.72Ref: TM-T6830
1mg118.00€5mg295.00€1mL*10mM (DMSO)355.00€10mg475.00€25mg773.00€50mg1,071.00€100mg1,423.00€500mg2,862.00€Carfilzomib
CAS:Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.Formula:C40H57N5O7Purity:99.6% - 99.84%Color and Shape:White SolidMolecular weight:719.91MDL-28170
CAS:MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.Formula:C22H26N2O4Purity:95.06%Color and Shape:SolidMolecular weight:382.45Ref: TM-T2470
1mg34.00€2mg49.00€5mg71.00€1mL*10mM (DMSO)75.00€10mg90.00€25mg128.00€50mg167.00€100mg284.00€ISOGINKGETIN
CAS:ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.Formula:C32H22O10Purity:98% - 99.75%Color and Shape:Yellow SolidMolecular weight:566.51Oprozomib
CAS:Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.Formula:C25H32N4O7SPurity:98% - 99.87%Color and Shape:White SolidMolecular weight:532.61UAMC00039 dihydrochloride
CAS:UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 of 0.48 nM.Formula:C16H26Cl3N3OPurity:99.70%Color and Shape:SolidMolecular weight:382.76MUN57694
CAS:MUN57694 is an inhibitor of 26S proteasome.Formula:C23H25N3O4Purity:99%Color and Shape:White SolidMolecular weight:407.46Ref: TM-T9090
2mg35.00€5mg52.00€1mL*10mM (DMSO)64.00€10mg86.00€25mg145.00€50mg210.00€100mg296.00€200mg414.00€Tomatine
CAS:Tomatine (lycopersicin) is an antiproliferatve agent of breast adenocarcinoma cells.Formula:C50H83NO21Purity:98.42% - 99.94%Color and Shape:SolidMolecular weight:1034.19MG-101
CAS:MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.Formula:C20H37N3O4Purity:97.02% - 98%Color and Shape:SolidMolecular weight:383.53Bortezomib-pinanediol
CAS:Bortezomib-pinanediol is a proteasome inhibitor. is a prodrug of Bortezomib.Formula:C29H39BN4O4Purity:97.5%Color and Shape:SolidMolecular weight:518.46DD1
CAS:DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.Formula:C16H14N2O3Purity:99.57%Color and Shape:SolidMolecular weight:282.29Tripterin
CAS:Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.Formula:C29H38O4Purity:98.56% - 99.8%Color and Shape:Orange SolidMolecular weight:450.61Proteasome inhibitor IX
CAS:Proteasome inhibitor IX (PS-IX) is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM).Formula:C20H21B2NO5Purity:99.77%Color and Shape:SolidMolecular weight:377.01Brensocatib
CAS:Brensocatib (AZD7986) is a Dipeptidyl peptidase 1 (DPP1) inhibitor (pIC50s: 6.85, 7.7, 7.6, 7.8, and 7.8 in human, rat, mouse, rabbit, and dog, respectively).Formula:C23H24N4O4Purity:97.55% - 98.69%Color and Shape:SolidMolecular weight:420.46
