Stem Cells
Stem cell inhibitors are compounds that specifically target stem cells and their signaling pathways, affecting their ability to self-renew and differentiate. These inhibitors are crucial in research focused on controlling stem cell behavior, understanding developmental processes, and developing therapies for diseases like cancer, where stem cells are thought to play a key role. At CymitQuimica, we offer a variety of stem cell inhibitors to support your research in regenerative medicine, developmental biology, and oncology.
Found 234 products of "Stem Cells"
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BMP signaling agonist sb4
CAS:BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)Formula:C14H10BrNOSPurity:99.48% - 99.805%Color and Shape:SolidMolecular weight:320.2Ref: TM-T7799
5mg44.00€10mg57.00€25mg94.00€50mg119.00€100mg177.00€200mg268.00€500mg465.00€1mL*10mM (DMSO)48.00€BMS986260
CAS:BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM).Formula:C18H12ClFN6OPurity:97.67%Color and Shape:SolidMolecular weight:382.78ZINC00881524
CAS:ZINC00881524 (ROCK inhibitor) is an effective and specific ROCK inhibitor.
Formula:C21H20N2O3SPurity:99.48%Color and Shape:SolidMolecular weight:380.46Adavivint
CAS:Adavivint (Adavivint (SM04690)) (SM04690) is a Wnt pathway inhibitor.
Formula:C29H24FN7OPurity:98.27% - 98.6%Color and Shape:SolidMolecular weight:505.55Porcn-IN-1
CAS:Porcn-IN-1 (Porcupine-IN-1) is an effective porcupine inhibitor (IC50: 0.5±0.2 nM).Formula:C25H19FN4OPurity:99.15%Color and Shape:SolidMolecular weight:410.44BIO-013077-01
CAS:BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.Formula:C17H13N5Purity:99.87%Color and Shape:SolidMolecular weight:287.32Ref: TM-T8330
1mg50.00€5mg92.00€10mg140.00€25mg273.00€50mg393.00€100mg557.00€200mg753.00€1mL*10mM (DMSO)138.00€IWP-O1
CAS:IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.Formula:C26H20N6OPurity:99.12%Color and Shape:SolidMolecular weight:432.48Ref: TM-T5342
2mg39.00€5mg64.00€10mg101.00€25mg163.00€50mg226.00€100mg320.00€200mg459.00€1mL*10mM (DMSO)70.00€Tegatrabetan
CAS:Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.Formula:C28H36N4O6S2Purity:98.01% - 99.18%Color and Shape:SolidMolecular weight:588.74Ref: TM-T5642
1mg40.00€2mg52.00€5mg85.00€10mg124.00€25mg210.00€50mg334.00€100mg565.00€1mL*10mM (DMSO)96.00€SRI-011381 hydrochloride
CAS:SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.Formula:C20H32ClN3OPurity:99.32% - 99.41%Color and Shape:SolidMolecular weight:365.94Ref: TM-T5129
1mg34.00€2mg44.00€5mg66.00€10mg105.00€25mg215.00€50mg334.00€100mg497.00€200mg755.00€1mL*10mM (DMSO)73.00€AZD1080
CAS:AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.Formula:C19H18N4O2Purity:97.72% - 99.75%Color and Shape:SolidMolecular weight:334.37Ref: TM-T1741
1mg43.00€2mg56.00€5mg85.00€10mg124.00€25mg219.00€50mg350.00€100mg429.00€1mL*10mM (DMSO)63.00€IQ 1
CAS:IQ 1 has multiple roles, such as maintaining the multifunctionality of mouse ESCs, decreasing Wnt-stimulated phosphorylation, blocking PP2A/Nkd interactions.
Formula:C21H22N4O2Purity:98.57% - ≥95%Color and Shape:SolidMolecular weight:362.42ITD-1
CAS:ITD-1 is a potent and highly selective TGFβ pathway inhibitor.Formula:C27H29NO3Purity:99.89% - >99.99%Color and Shape:SolidMolecular weight:415.52β-catenin-IN-2
CAS:β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.Formula:C15H14FN3Purity:99.93%Color and Shape:SolidMolecular weight:255.29Ref: TM-T9696
1mg96.00€5mg227.00€10mg359.00€25mg607.00€50mg868.00€100mg1,169.00€500mg2,365.00€1mL*10mM (DMSO)264.00€Afuresertib hydrochloride
CAS:Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)
Formula:C18H18Cl3FN4OSPurity:99.96%Color and Shape:SolidMolecular weight:463.8Galunisertib
CAS:Galunisertib (LY2157299) is a selective TGF-β receptor type I (TGF-βRI) inhibitor. Galunisertib has antitumor activity. Cost-effective and quality-assured.Formula:C22H19N5OPurity:97.09% - 99.98%Color and Shape:SolidMolecular weight:369.42Ref: TM-T2510
1g657.00€5mg46.00€10mg52.00€25mg84.00€50mg114.00€100mg178.00€200mg269.00€500mg442.00€1mL*10mM (DMSO)52.00€I3MT-3
CAS:I3MT-3 (HMPSNE) is a selective inhibitor of 3MST, targeting active site cysteine residues and permeating cell membranes.Formula:C17H14N2O2SPurity:99.76%Color and Shape:SolidMolecular weight:310.37exo-IWR-1
CAS:exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin
Formula:C25H19N3O3Purity:97.41%Color and Shape:SolidMolecular weight:409.44YO-01027
CAS:YO-01027 (DBZ) is a potent γ-secretase inhibitor.
Formula:C26H23F2N3O3Purity:97.21% - 99.58%Color and Shape:SolidMolecular weight:463.48Belumosudil
CAS:Belumosudil (Rezurock) is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).Formula:C26H24N6O2Purity:97.64% - 98.59%Color and Shape:SolidMolecular weight:452.51Ref: TM-T6867
2mg48.00€5mg73.00€10mg90.00€25mg166.00€50mg250.00€100mg376.00€500mg895.00€1mL*10mM (DMSO)79.00€GSK269962A
CAS:GSK269962A (GSK269962A HCl) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.Formula:C29H30N8O5Purity:99.14% - 99.71%Color and Shape:SolidMolecular weight:570.6IHR-1
CAS:IHR-1, a Smo inhibitor (IC50 7.6 nM), blocks Hedgehog pathway, not Wnt/Notch, and prevents Smo in primary cilium.Formula:C20H12Cl4N2O2Purity:97.02%Color and Shape:SolidMolecular weight:454.13Ref: TM-T24159
2mg33.00€5mg50.00€10mg80.00€25mg131.00€50mg193.00€100mg290.00€200mg416.00€1mL*10mM (DMSO)55.00€MRT-14
CAS:MRT-14 is a potent Smo antagonist and can be used in several types of cancers linked to abnormal Hh signaling studies.Formula:C24H24N4O5Purity:99.54%Color and Shape:SolidMolecular weight:448.47Lats-IN-1
CAS:Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.Formula:C18H14N4OSPurity:97.54% - 99.79%Color and Shape:SolidMolecular weight:334.39Ref: TM-T9053
1mg52.00€2mg73.00€5mg105.00€10mg167.00€25mg309.00€50mg416.00€100mg592.00€200mg842.00€1mL*10mM (DMSO)118.00€LY3200882
CAS:LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI).Formula:C24H29N5O3Purity:99.46% - 99.63%Color and Shape:SolidMolecular weight:435.52XMU-MP-1
CAS:XMU-MP-1 is a reversible and selective MST1/2 kinase inhibitor, IC50 values for MST1 and MST2 are 71.1 nM and 38.1 nM, respectively. High-Quality, Low-Cost!Formula:C17H16N6O3S2Purity:99.68% - 99.86%Color and Shape:SolidMolecular weight:416.48Ref: TM-T4212
1mg52.00€2mg79.00€5mg97.00€10mg153.00€25mg305.00€50mg512.00€100mg663.00€1mL*10mM (DMSO)95.00€Fosciclopirox
CAS:Fosciclopirox (CPX-POM), the phosphoryloxymethyl ester of CPX (Ciclopirox Prodrug, CPX-POM), selectively delivers the active metabolite, CPX, to the entireFormula:C13H20NO6PPurity:99.83%Color and Shape:SolidMolecular weight:317.27Ref: TM-T9422
2mg35.00€5mg52.00€10mg90.00€25mg170.00€50mg259.00€100mg383.00€200mg545.00€1mL*10mM (DMSO)58.00€AR-A014418
CAS:AR-A014418 (GSK 3β inhibitor VIII) is an ATP-competitive, and selective GSK3β inhibitor.Formula:C12H12N4O4SPurity:>99.99% - ≥95%Color and Shape:SolidMolecular weight:308.31SRI-011381
CAS:SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.Formula:C20H31N3OPurity:98.64%Color and Shape:SolidMolecular weight:329.48SB 216763
CAS:SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).Formula:C19H12Cl2N2O2Purity:98.9% - 99.13%Color and Shape:SolidMolecular weight:371.22Ref: TM-T3077
2mg39.00€5mg52.00€10mg79.00€25mg131.00€50mg197.00€100mg334.00€500mg803.00€1mL*10mM (DMSO)52.00€PF-5274857
CAS:PF-5274857: selective hedgehog pathway inhibitor (IC50: 5.8 nM, Ki: 4.6 nM), treats brain tumors, crosses blood-brain barrier, orally stable.Formula:C20H25ClN4O3SPurity:98.53%Color and Shape:SolidMolecular weight:436.96MYF-01-37
CAS:MYF-01-37 (1-[3-Methyl-3-[3-(trifluoromethyl)anilino]pyrrolidin-1-yl]prop-2-en-1-one) is a novel covalent TEAD inhibitor.Formula:C15H17F3N2OPurity:99.46% - 99.5%Color and Shape:SolidMolecular weight:298.3Ref: TM-T22372
2mg38.00€5mg57.00€10mg90.00€25mg166.00€50mg281.00€100mg421.00€500mg888.00€1mL*10mM (DMSO)63.00€SD-208
CAS:SD-208 (ALK5 Inhibitor V), a selective TGF-βRI (ALK5) inhibitor (IC50: 48 nM), is >100-fold selectivity over TGF-βRII.Formula:C17H10ClFN6Purity:98.72% - 99.65%Color and Shape:SolidMolecular weight:352.75VP3.15 dihydrobromide
CAS:VP3.15 dihydrobromide: potent, oral, CNS-penetrant PDE7/GSK3 inhibitor; IC50s: PDE7- 1.59 μM, GSK- 0.88 μM.Formula:C20H24Br2N4OSPurity:99.67% - ≥95%Color and Shape:SolidMolecular weight:528.3LGK974
CAS:LGK974 (NVP-LGK974) is a selective PORCN inhibitor that blocks Wnt signaling, used in metastatic colorectal and head/neck cancer trials. IC50: 0.4 nM.Formula:C23H20N6OPurity:98.8% - >99.99%Color and Shape:SolidMolecular weight:396.44Ref: TM-T2618
1mg46.00€2mg62.00€5mg90.00€10mg156.00€25mg288.00€50mg515.00€100mg737.00€1mL*10mM (DMSO)90.00€SJ000291942
CAS:SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway.Formula:C16H15FN2O4Purity:99.66%Color and Shape:SolidMolecular weight:318.3Ref: TM-T4662
1mg34.00€2mg44.00€5mg63.00€10mg100.00€25mg205.00€50mg349.00€100mg557.00€200mg790.00€1mL*10mM (DMSO)71.00€Indirubin-3′-oxime
CAS:Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.
Formula:C16H11N3O2Purity:98.34%Color and Shape:SolidMolecular weight:277.28RKI1313
CAS:RKI1313 (RKI-1313) was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, and invasionFormula:C17H16N4O2SPurity:99.53% - ≥95%Color and Shape:SolidMolecular weight:340.4Ref: TM-T2011
1mg70.00€5mg142.00€10mg207.00€25mg369.00€50mg540.00€100mg772.00€500µg49.00€1mL*10mM (DMSO)160.00€LSKL, Inhibitor of Thrombospondin TSP-1 2TFA
LSKL, Inhibitor of Thrombospondin TSP-1 acetate is activation of TGF-β .Formula:C25H44F6N6O9Purity:99.75%Color and Shape:SolidMolecular weight:686.64Ref: TM-T7676
2mg42.00€5mg54.00€10mg84.00€25mg138.00€50mg207.00€100mg316.00€200mg442.00€1mL*10mM (DMSO)93.00€Kartogenin
CAS:Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.Formula:C20H15NO3Purity:96.25% - 97.79%Color and Shape:SolidMolecular weight:317.34TBB
CAS:TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).
Formula:C6HBr4N3Purity:98.51% - 99.45%Color and Shape:Off-White SolidMolecular weight:434.71BML-284
CAS:BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.Formula:C19H18N4O3Purity:99.91% - 99.921%Color and Shape:SolidMolecular weight:350.37Ref: TM-T3144
5mg60.00€10mg88.00€25mg140.00€50mg253.00€100mg427.00€200mg615.00€500mg938.00€1mL*10mM (DMSO)66.00€IWP L6
CAS:IWP L6 (Porcn Inhibitor III) is an extremely effective Porcn inhibitor (EC50: 0.5 nM).
Formula:C25H20N4O2S2Purity:99.51% - >99.99%Color and Shape:SolidMolecular weight:472.58PF-4800567
CAS:PF-4800567 is a selective inhibitor of casein kinase 1ε (CK1ε; IC50 = 32 nM) with greater than 20-fold selectivity over CK1δ.Formula:C17H18ClN5O2Purity:99.74% - 99.76%Color and Shape:SolidMolecular weight:359.81PRI-724
CAS:PRI-724 is a second-generation, selective small molecule inhibitor of the β-catenin/CBP interaction.Cost-effective and quality-assured.
Formula:C33H35N6O7PPurity:98.25% - 99.11%Color and Shape:SoildMolecular weight:658.64EasyStep Human Cys-C(CystatinC) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human Cys-C, and the Human Cys-C standard plate wells that pre-coated using protein-related techniques are provided separately. Standard/Sample Diluent Buffer or samples are added to the appropriate microtiter plate wells ,then added a HRP-conjugated antibody specific to Human Cys-C. After TMB substrate solution is added, only those wells that contain Human Cys-C and HRP-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human Cys-C in the samples is then determined by comparing the OD of the samples to the standard curve.Color and Shape:Colourless TransparentliquidVT107
CAS:VT107 is a potent pan-TEAD autopalmitoylation inhibitor. VT-107 can be used in cancer therapy research.Cost-effective and quality-assured.Formula:C25H20F3N3OPurity:99.72% - 99.92%Color and Shape:SolidMolecular weight:435.44Ref: TM-T35545
1mg130.00€5mg314.00€10mg477.00€25mg768.00€50mg1,045.00€100mg1,406.00€200mg1,882.00€1mL*10mM (DMSO)343.00€RO7185876
CAS:RO7185876 is a selective gamma secretase modulator, which can be used in the study of Alzheimer's disease.Formula:C25H28F3N7Purity:99.50%Color and Shape:SolidMolecular weight:483.532CHIR 98024
CAS:CHIR 98024: strong GSK-3α/β blocker, IC50 0.65/0.58 nM, selective over Cdc2/ERK2.Formula:C20H17Cl2N9O2Purity:99.45%Color and Shape:SolidMolecular weight:486.31Ref: TM-T3074
1mg44.00€2mg55.00€5mg96.00€10mg153.00€25mg298.00€50mg487.00€100mg705.00€1mL*10mM (DMSO)97.00€YAP/TAZ inhibitor-2
CAS:Potent oral TEAD-YAP/TAZ inhibitor-2 with 3 nM EC50; exhibits anti-proliferative and antitumor effects.Formula:C19H14F4N4OPurity:98.65%Color and Shape:SoildMolecular weight:390.33Ref: TM-T60218
1mg87.00€2mg113.00€5mg177.00€10mg281.00€25mg475.00€50mg687.00€100mg964.00€500mg1,918.00€1mL*10mM (DMSO)197.00€Ginisortamab
CAS:Ginisortamab (UCB6114) is a fully humanized monoclonal antibody targeting Gremlin-1, IC50=8.2 nM and 9 nM against human and mouse Gremlin-1, respectively.Purity:95% - 96.0% (SDS-PAGE); 97.0% (SEC-HPLC)Color and Shape:LiquidMolecular weight:147.55 kDa
