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Tyrosine Kinase/Adaptors

Tyrosine Kinase/Adaptors

Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.

Subcategories of "Tyrosine Kinase/Adaptors"

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Found 1375 products of "Tyrosine Kinase/Adaptors"

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  • BMS-777607

    CAS:
    <p>BMS-777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3.</p>
    Formula:C25H19ClF2N4O4
    Purity:98.16% - 98.56%
    Color and Shape:Solid
    Molecular weight:512.89
  • GIP (1-30) amide,human

    CAS:
    <p>GIP (1-30) amide (Human) is a glucose-dependent insulinotropic polypeptide that stimulates insulin secretion, reducing postprandial glycemic issues.</p>
    Formula:C162H240N40O47S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3531.94
  • Varlitinib Tosylate

    CAS:
    <p>Varlitinib Tosylate is a selective and potent inhibitor of ErbB1(EGFR) and ErbB2(HER2).</p>
    Formula:C36H35ClN6O8S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:811.34
  • Pertuzumab

    CAS:
    <p>Pertuzumab (anti-HER2) a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors impairs the ability of HER2</p>
    Purity:98.00%
    Color and Shape:Liquid
    Molecular weight:148 kDa
  • GIP (1-30) amide, porcine TFA


    <p>GIP (1-30) amide, porcine TFA: a full GIP receptor agonist, similar to natural GIP(1-42), stimulates insulin, mildly inhibits gastric acid.</p>
    Color and Shape:Liquid
  • DA-JC4

    CAS:
    <p>DA-JC4: dual GLP-1/GIP agonist, for neurological disease research and insulin pathway studies.</p>
    Formula:C225H346N56O65
    Color and Shape:Solid
    Molecular weight:4875.49
  • Cixutumumab

    CAS:
    <p>Cixutumumab (IMC-A12), a humanized monoclonal antibody targeting IGF-1R, exhibits high affinity and inhibits ligand-dependent receptor activation, impeding</p>
    Purity:98.5% (SDS-PAGE); 97.5% (SEC-HPLC) - 98.5% (SDS-PAGE); 97.5% (SEC-HPLC)
    Color and Shape:Liquid
  • MS9427

    CAS:
    <p>MS9427: PROTAC EGFR degrader, 7.1 nM (WT), 4.3 nM (L858R); targets mutant via UPS and autophagy; inhibits NSCLC cell growth; anticancer research.</p>
    Formula:C48H58ClFN8O12
    Color and Shape:Solid
    Molecular weight:993.47
  • HER2/neu (654-662) GP2

    CAS:
    <p>Phage display selected Affibody ligands for HER2/neu from a protein library based on a 58-residue Staphylococcal protein A Z domain.</p>
    Formula:C42H77N9O11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:884.11
  • CREBtide

    CAS:
    <p>CREBtide is a synthetic substrate for PKA (Km=3.9 µM), which is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein).</p>
    Formula:C73H129N29O19
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1716.99
  • KN1022

    CAS:
    <p>KN1022 is an inhibitor of phosphorylation of platelet-derived growth factor (PDGF) receptor with IC50 of 0.26 μM.</p>
    Formula:C21H22N6O5
    Purity:99.68%
    Color and Shape:Soild
    Molecular weight:438.44
  • JAK 3 inhibitor IV

    CAS:
    <p>JAK 3 inhibitor IV (ZM 39923 hydrochloride) is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to</p>
    Formula:C16H19NO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:241.33
  • ALKBH5-IN-5

    CAS:
    <p>ALKBH5-IN-5 is a highly selective, potent and covalently binding ALKBH5 inhibitor that alters m6A levels on mRNA, induces apoptosis, antitumo.</p>
    Formula:C13H13NO3
    Purity:99.54%
    Color and Shape:Soild
    Molecular weight:231.25
  • FLT3-ITD-IN-2


    <p>FLT3-ITD-IN-2 (Compound A1) is an inhibitor of the FLT3-ITD kinase, exhibiting an IC50 of 2.12 nM. It effectively suppresses the proliferation of the FLT3-dependent human AML cell line MOLM-13, with an IC50 of 25.65 nM. FLT3-ITD-IN-2 demonstrates antitumor activity against acute myeloid leukemia.</p>
    Formula:C39H50N8O6
    Color and Shape:Solid
    Molecular weight:726.86
  • DSPE-PEG2000-GE11


    <p>DSPE-PEG2000-GE11 is a PEG compound composed of DSPE and an EGFR-targeting peptide (GE11). GE11 is applicable for cancer cells that overexpress EGFR. DSPE-PEG2000-GE11 is utilized in drug delivery.</p>
    Color and Shape:Odour Solid
  • PKG inhibitor peptide

    CAS:
    <p>PKG inhibitor; mimics H2B phosphorylation site; Ki=86mM; blocks synthetic substrates, not histone phosphorylation; stops PKA activity on histones.</p>
    Formula:C38H74N18O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:943.12
  • KYL peptide

    CAS:
    <p>EphA4 inhibitor, Kd 0.8 μM, blocks EphA4-EphrinA5; avoids AβO damage, preserves spines &amp; LTP; long half-life (8-12h), neuroprotective.</p>
    Formula:C74H108N14O17
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1465.75
  • Gastric Inhibitory Peptide (1-42) (porcine) TFA


    <p>Gastric Inhibitory Peptide (1-42) (porcine) TFA is a glucose-dependent insulinotropic polypeptide released by intestinal K-cells.</p>
    Formula:C225H342N60O66S·XCF3COOH
    Color and Shape:Solid
    Molecular weight:4975.55
  • Tephrosin

    CAS:
    <p>Tephrosin induces degradation of of EGFR and ErbB2 by inducing internalization of the receptors, has potent antitumor activities.</p>
    Formula:C23H22O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:410.42
  • PROTAC EGFR degrader 2


    <p>Potent PROTAC EGFR degrader 2; IC50: 4.0 nM, DC50: 36.51 nM; inhibits cell growth; for NTR-responsive synthesis.</p>
    Formula:C58H72ClFN12O8S
    Color and Shape:Solid
    Molecular weight:1151.78