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Tyrosine Kinase/Adaptors

Tyrosine Kinase/Adaptors

Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.

Subcategories of "Tyrosine Kinase/Adaptors"

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Found 1259 products of "Tyrosine Kinase/Adaptors"

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  • PD-089828
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    PD-089828

    CAS:
    <p>PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).</p>
    Formula:C18H18Cl2N6O
    Purity:97.39%
    Color and Shape:Solid
    Molecular weight:405.28

    Ref: TM-T8976

  • AST 487
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    AST 487

    CAS:
    <p>AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.</p>
    Formula:C26H30F3N7O2
    Purity:98.17% - 99.56%
    Color and Shape:Solid
    Molecular weight:529.56

    Ref: TM-T4053

  • PD173955
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    PD173955

    CAS:
    <p>PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR and</p>
    Formula:C21H16Cl2N4OS
    Purity:98.52% - 98.99%
    Color and Shape:Solid
    Molecular weight:443.35

    Ref: TM-T3063

  • FGFR2-IN-3
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    FGFR2-IN-3

    CAS:
    <p>FGFR2-IN-3 is an orally active selective FGFR2 inhibitor[1].</p>
    Formula:C28H24FN7O2
    Purity:99.63%
    Color and Shape:Soild
    Molecular weight:509.53

    Ref: TM-T60185

  • Cavutilide
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    Cavutilide

    CAS:
    <p>Cavutilide has antiarrhythmic activity, inhibits hERG K(+) channels, and can be used to study heart failure and persistent atrial fibrillation.</p>
    Formula:C22H26FN3O3
    Purity:99.82% - 99.85%
    Color and Shape:Solid
    Molecular weight:399.458

    Ref: TM-T61913

  • H-8 hydrochloride
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    H-8 hydrochloride

    CAS:
    H-8 hydrochloride is a reversible and ATP-competitive PKA inhibitor. It can be used to study metabolic diseases.
    Formula:C12H17Cl2N3O2S
    Purity:99.93%
    Color and Shape:White To Off-White Crystalline Solid
    Molecular weight:338.25

    Ref: TM-T22832

  • Toceranib
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    Toceranib

    CAS:
    <p>Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.</p>
    Formula:C22H25FN4O2
    Purity:97.14%
    Color and Shape:Solid
    Molecular weight:396.46

    Ref: TM-T13178

  • PDGFR Tyrosine Kinase Inhibitor III
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    PDGFR Tyrosine Kinase Inhibitor III

    CAS:
    <p>PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) (PDGF Receptor Tyrosine Kinase Inhibitor III) is a multikinase inhibitor that</p>
    Formula:C27H27N5O4
    Purity:99.50%
    Color and Shape:Soild
    Molecular weight:485.53

    Ref: TM-T60108

  • Indirubin Derivative E804
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    Indirubin Derivative E804

    CAS:
    Indirubin Derivative E804 is a potent insulin-like growth factor type 1 receptor (IGF1R) inhibitor with potential antitumor activity.
    Formula:C20H19N3O4
    Purity:98.54%
    Color and Shape:Solid
    Molecular weight:365.38

    Ref: TM-T11654

  • Gefitinib hydrochloride
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    Gefitinib hydrochloride

    CAS:
    Obtustatin triacetate is an integrin derived from the venom of Vipera lebetina obtusa and is an α1β1 integrin and in vivo angiogenesis inhibitor.
    Formula:C22H25Cl2FN4O3
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:483.36

    Ref: TM-T1181L

  • Canertinib dihydrochloride
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    Canertinib dihydrochloride

    CAS:
    Canertinib dihydrochloride (PD-183805 dihydrochloride) is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and
    Formula:C24H27Cl3FN5O3
    Purity:99.13% - >99.99%
    Color and Shape:Solid
    Molecular weight:558.86

    Ref: TM-T2501

  • Almonertinib hydrochloride
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    Almonertinib hydrochloride

    CAS:
    <p>Almonertinib hydrochloride (HS-10296 hydrochloride) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation.</p>
    Formula:C30H36ClN7O2
    Purity:98.01% - 98.12%
    Color and Shape:Solid
    Molecular weight:562.1

    Ref: TM-T5675

  • (Rac)-SAR131675
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    (Rac)-SAR131675

    CAS:
    <p>(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor, which inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells.</p>
    Formula:C18H22N4O4
    Purity:98.34% - 99.1%
    Color and Shape:Solid
    Molecular weight:358.39

    Ref: TM-T3691

  • Naquotinib mesylate
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    Naquotinib mesylate

    CAS:
    Naquotinib mesylate (ASP8273 (mesylate)) is an orally available, mutant-selective and irreversible inhibitor of EGFR(iC50s of 8-33 nM and 230 nM for toward EGFR
    Formula:C31H46N8O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:658.81

    Ref: TM-T12175

  • NVP-BSK805
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    NVP-BSK805

    CAS:
    NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.
    Formula:C27H28F2N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:490.55

    Ref: TM-T5049

  • BMS-690514
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    BMS-690514

    CAS:
    BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.
    Formula:C19H24N6O2
    Purity:99.08%
    Color and Shape:Solid
    Molecular weight:368.43

    Ref: TM-T14677

  • CymitQuimica logo
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    Fidasimtamab

    CAS:
    Fidasimtamab, a recombinant human IgG1 bispecific antibody, targets both HER2 and PD-1, bridging T cells and tumor cells to modulate immune responses.
    Purity:95% - 98.0% (SDS-PAGE); 98.3% (SEC-HPLC)
    Color and Shape:Liquid

    Ref: TM-T77007

  • EGFR T790M/L858R-IN-8
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    EGFR T790M/L858R-IN-8

    CAS:
    EGFRT790M/L858R-IN-8 (compound 9) is a potent inhibitor of EGFR, specifically targeting the EGFRT790M/L858R mutations with an IC50 of 56.8 μM. This compound does not show significant antiproliferative effects on cancer cell lines A549, A431, and NHI-H1975.
    Formula:C16H11BrN2O3
    Color and Shape:Solid
    Molecular weight:359.17

    Ref: TM-T88087

  • CymitQuimica logo
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    Fulranumab

    CAS:
    <p>Fulranumab (AMG-403) is a humanised monoclonal antibody targeting NGF, analgesic effects, and can be used for the study of chronic pain.</p>
    Purity:95%
    Color and Shape:Liquid

    Ref: TM-T82367

  • CymitQuimica logo
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    Dusigitumab

    CAS:
    <p>Dusigitumab (MEDI573) is a fully humanised monoclonal antibody targeting IGF1/IGF2, inhibiting IGF1/IGF2-induced IGF-1R phosphorylation.</p>
    Purity:95% - 95%
    Color and Shape:Liquid

    Ref: TM-T80605