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Tyrosine Kinase/Adaptors

Tyrosine Kinase/Adaptors

Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.

Subcategories of "Tyrosine Kinase/Adaptors"

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Found 1342 products of "Tyrosine Kinase/Adaptors"

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  • CSF1R-IN-3

    CAS:
    <p>CSF1R-IN-3 is an orally effective CSF-1R inhibitor with an IC50 value of 2.1 nM.</p>
    Formula:C30H38N8O4
    Purity:97.31%
    Color and Shape:Solid
    Molecular weight:574.67
  • VEGFR-3-IN-1

    CAS:
    <p>VEGFR-3-IN-1, a potent VEGFR3 inhibitor (IC50=110.4 nM), hinders tumor growth and VEGFR3 signaling, affecting HDLEC and MDA-MB cell proliferation/migration.</p>
    Formula:C29H29ClF3N7OS
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:616.1
  • A-935142

    CAS:
    <p>A-935142 enhances hERG (Kv 11.1) channels, slows inactivation, promotes activation, and shortens repolarization.</p>
    Formula:C18H19F3N2O2
    Purity:98.97% - 99.91%
    Color and Shape:Solid
    Molecular weight:352.35
  • RET-IN-3

    CAS:
    <p>RET-IN-3 is a RETV804M kinase inhibitor with potential anticancer activity for the study of non-small cell lung cancer.</p>
    Formula:C18H21N5O2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:339.39
  • SKLB 1028

    CAS:
    <p>SKLB 1028, an oral EGFR/FLT3/Abl inhibitor, excels in AML and CML with Abl mutations.</p>
    Formula:C24H29N9
    Purity:99.90% - >99.99%
    Color and Shape:Solid
    Molecular weight:443.55
  • Tilfrinib

    CAS:
    <p>Tilfrinib is an effective and selective inhibitor of breast tumor kinase(Brk, IC50 = 3.15 nM) which displays anti-proliferative and anti-tumor activities.</p>
    Formula:C17H13N3O
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:275.3
  • DDR Inhibitor

    CAS:
    <p>DDR inhibitor is a potent discidin domain receptor (DDR) inhibitor. The IC50 of DDR2 is 3.3 nM, and DDR1 has 53% inhibition at 1.5 nM.</p>
    Formula:C23H20FN5O2
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:417.44
  • PKI-166

    CAS:
    <p>PKI-166: oral EGF-R tyrosine kinase inhibitor (IC50: 0.7 nM), halts growth &amp; spread of many human cancers, including pancreatic.</p>
    Formula:C20H18N4O
    Purity:99.2%
    Color and Shape:Solid
    Molecular weight:330.38
  • LY 456236 hydrochloride

    CAS:
    <p>LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM.</p>
    Formula:C16H16ClN3O2
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:317.77
  • Tyrphostin A25

    CAS:
    <p>Tyrphostin A25 (Tyrphostin AG 82) is a specific EGFR tyrosine kinase inhibitor and GPR35 agonist with an IC50 value of 0.94 μM for GPR35 and an EC50 value of 5.</p>
    Formula:C10H6N2O3
    Purity:98.76%
    Color and Shape:Yellow Green Powder /Off-White Solid
    Molecular weight:202.17
  • Epitinib succinate

    CAS:
    <p>Epitinib succinate (HMPL-813 succinate) is an orally active and brain penetration EGFR tyrosine kinase inhibitor and can be used in studies about cancer.</p>
    Formula:C28H32N6O6
    Purity:98.02% - 99.79%
    Color and Shape:Solid
    Molecular weight:548.59
  • ProINDY

    CAS:
    ProINDY (Pro-indy) is a potent DYRK inhibitor that activates NFAT for the study of Down syndrome.
    Formula:C14H15NO3S
    Purity:97.19%
    Color and Shape:Solid
    Molecular weight:277.34
  • EMI1

    CAS:
    <p>EMI1 targets mutated EGFR in drug-resistant NSCLC research.</p>
    Formula:C20H18N2O3
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:334.37
  • AMPK-IN-3

    CAS:
    <p>AMPK-IN-3: potent, selective AMPK (α2/α1) &amp; KDR inhibitor; IC50: 60.7/107/3820 nM; anticancer in K562 cells.</p>
    Formula:C25H33N5O3
    Purity:99.13%
    Color and Shape:Solid
    Molecular weight:451.56
  • CGP77675

    CAS:
    <p>CGP77675 (ZINC1488120) is a potent and selective inhibitor of Src family kinase with IC50s of 5-20 and 40 nM for the phosphorylation of peptide substrates and</p>
    Formula:C26H29N5O2
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:443.54
  • Pimicotinib

    CAS:
    <p>Pimicotinib (ABSK021) is a potent CSF1R inhibitor with antitumor activity and can be used to study advanced solid tumors.</p>
    Formula:C22H24N6O3
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:420.46
  • Chiauranib

    CAS:
    <p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>
    Formula:C27H21N3O3
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:435.47
  • Rezivertinib

    CAS:
    <p>Rezivertinib (BPI-7711) is an EGFR inhibitor with antitumor activity and can be used to study central nervous system diseases.</p>
    Formula:C27H30N6O3
    Purity:99.26% - 99.89%
    Color and Shape:Solid
    Molecular weight:486.57
  • c-Fms-IN-13

    CAS:
    <p>c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor (IC50= 17 nM). c-Fms-IN-13 is an anti-inflammatory agent.</p>
    Formula:C22H26N4O2
    Purity:99.93% - 99.97%
    Color and Shape:Solid
    Molecular weight:378.47
  • (E)-FeCP-oxindole

    CAS:
    <p>(E)-FeCP-oxindole 是一种 VEGFR2 抑制剂,IC50 为 214 nM。</p>
    Formula:C19H15FeNO
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:329.17