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Tyrosine Kinase/Adaptors

Tyrosine Kinase/Adaptors

Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.

Subcategories of "Tyrosine Kinase/Adaptors"

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Found 1342 products of "Tyrosine Kinase/Adaptors"

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  • EGFR-IN-99
    Targetmol
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    EGFR-IN-99

    CAS:
    <p>EGFR-IN-99 (JBJ-03-142-02) is an EGFR and HER2 Exon 20 insertion mutation inhibitor for the study of non-small cell lung cancer (NSCLC).</p>
    Formula:C25H22FN7O3
    Purity:97.75%
    Color and Shape:Solid
    Molecular weight:487.49

    Ref: TM-T35901

  • A 419259 trihydrochloride
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    A 419259 trihydrochloride

    CAS:
    A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).
    Formula:C29H37Cl3N6O
    Purity:99.75% - 99.96%
    Color and Shape:Solid
    Molecular weight:592

    Ref: TM-TQ0132

  • Cloperastine fendizoate
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    Cloperastine fendizoate

    CAS:
    <p>Cloperastine fendizoate (Hustazol) inhibits the hERG K+ currents in a concentration-dependent manner (IC50: 27 nM).</p>
    Formula:C40H38ClNO5
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:648.19

    Ref: TM-T13619

  • GTP-14564
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    GTP-14564

    CAS:
    <p>GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3.</p>
    Formula:C15H10N2O
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:234.25

    Ref: TM-T71857

  • EGFR-IN-9
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    EGFR-IN-9

    CAS:
    <p>EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M).</p>
    Formula:C29H24N4O3
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:476.53

    Ref: TM-T11163

  • LDN-211904 oxalate
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    LDN-211904 oxalate

    CAS:
    <p>LDN-211904 oxalate (LDN211904 oxalate) is a selective and efficient EphB3 inhibitor with antitumor activity, useful in neurodegenerative disease research.</p>
    Formula:C21H21ClN4O5
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:444.87

    Ref: TM-T21762

  • Pz-1
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    Pz-1

    CAS:
    <p>Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth.</p>
    Formula:C26H26N6O2
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:454.52

    Ref: TM-T12598

  • I-OMe-Tyrphostin AG 538
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    I-OMe-Tyrphostin AG 538

    CAS:
    <p>I-OMe-Tyrphostin AG 538: IGF-1R &amp; PI5P4Kα inhibitor, ATP-competitive, IC50 of 1 µM, targets IGF-1R pathway, cytotoxic in nutrient-poor PANC1 cells.</p>
    Formula:C17H12INO5
    Purity:98.23%
    Color and Shape:Solid
    Molecular weight:437.19

    Ref: TM-T11593

  • Falnidamol
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    Falnidamol

    CAS:
    <p>Falnidamol (BIBX 1382), an oral selective EGFR inhibitor, IC50 3 nM, weak on ErbB2 and others, anti-cancer pyrimido-pyrimidine.</p>
    Formula:C18H19ClFN7
    Purity:98.816%
    Color and Shape:Solid
    Molecular weight:387.84

    Ref: TM-TQ0271

  • Tyrosine kinase-IN-6
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    Tyrosine kinase-IN-6

    CAS:
    <p>Tyrosine kinase-IN-6 is a potent inhibitor of RON splice variants, demonstrating significant anticancer and antineoplastic effects [1].</p>
    Formula:C37H31F2N5O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:695.73

    Ref: TM-T79612

  • 2′-Thioadenosine
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    2′-Thioadenosine

    CAS:
    <p>2'-Thioadenosine (PD157432) serves as a selective and irreversible inhibitor of ErbB-1 and ErbB-2 tyrosine kinases, demonstrating an IC50 value of 45 µM against</p>
    Formula:C10H13N5O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:283.31

    Ref: TM-T78634

  • DZD1516
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    DZD1516

    CAS:
    <p>DZD1516, a potent and selective HER2 inhibitor (IC50 = 0.56 nM), demonstrates good blood-brain barrier permeability and exhibits antitumor activity in both</p>
    Formula:C28H27F2N7O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:547.56

    Ref: TM-T79297

  • AXL-IN-14
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    AXL-IN-14

    CAS:
    <p>AXL-IN-14: orally active, potent AXL inhibitor (IC50=0.8 nM); hinders Gas6/AXL migration, invasion; lowers p-AXL, p-AKT; anti-tumor.</p>
    Formula:C32H24F2N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:566.55

    Ref: TM-T73310

  • VEGFR-2-IN-37
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    VEGFR-2-IN-37

    CAS:
    <p>VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.</p>
    Formula:C18H16N2O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.4

    Ref: TM-T80872

  • BT424
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    BT424

    CAS:
    BT424, a specific HCK inhibitor, modulates macrophage activation and autophagy in vitro, and mitigates inflammation and renal fibrosis in the UUO model [1].
    Formula:C22H15BCl2N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:421.08

    Ref: TM-T79516

  • Brepocitinib
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    Brepocitinib

    CAS:
    Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits JAK2/3 (IC50s: 77 nM/6.49 μM).
    Formula:C18H21F2N7O
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:389.4

    Ref: TM-TQ0010

  • Axl/Mer/CSF1R-IN-2
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    Axl/Mer/CSF1R-IN-2

    CAS:
    <p>Axl/Mer/CSF1R-IN-2 (Comp 4) serves as an inhibitor for Axl, Mer, and CSF1R [1].</p>
    Formula:C24H22F3N5O5
    Color and Shape:Solid
    Molecular weight:517.46

    Ref: TM-T85780

  • Cinsebrutinib
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    Cinsebrutinib

    CAS:
    <p>Cinsebrutinib, a Bruton's tyrosine kinase inhibitor, holds potential for research in cancer treatment.</p>
    Formula:C22H26FN3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:383.46

    Ref: TM-T79841

  • BMS-599626 Hydrochloride
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    BMS-599626 Hydrochloride

    CAS:
    <p>BMS-599626 HCl (AC480 HCl) is an oral inhibitor of HER1, HER2, HER4 kinases, potentially blocking tumor growth. IC50: 22/32/190 nM.</p>
    Formula:C27H28ClFN8O3
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:567.01

    Ref: TM-T5390

  • Terevalefim
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    Terevalefim

    CAS:
    Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor.
    Formula:C9H8N2S
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:176.24

    Ref: TM-T37596