Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(114 products)
- CSF-1R(42 products)
- EGFR(572 products)
- Ephrin Receptor(23 products)
- FLT(91 products)
- Fibroblast Growth Factor Receptor (FGFR)(169 products)
- HER(5 products)
- Hck(3 products)
- IGF-1R(91 products)
- PDGFR(126 products)
- PYK2(7 products)
- Src(80 products)
- TAM Receptor(32 products)
- Tie-2(21 products)
- Trk receptor(59 products)
- Tyrosine Kinases(26 products)
- VEGFR(267 products)
- c-Fms(108 products)
- c-Kit(102 products)
- c-Met/HGFR(129 products)
- c-RET(51 products)
Show 13 more subcategories
Found 1357 products of "Tyrosine Kinase/Adaptors"
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JGK-068S
CAS:<p>Compound I (JGK-068S) is a potent inhibitor of the epidermal growth factor receptor (EGFR) [1].</p>Formula:C22H23BrFN5O2Purity:98%Color and Shape:SolidMolecular weight:488.35TG 100572 Hydrochloride
CAS:<p>TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.</p>Formula:C26H27Cl2N5O2Purity:98%Color and Shape:SolidMolecular weight:512.43Pirtobrutinib
CAS:<p>Pirtobrutinib: a selective, non-covalent BTK inhibitor effective against BTK C481 mutations, causing tumor regression in lymphoma models.</p>Formula:C22H21F4N5O3Purity:99.76% - 99.94%Color and Shape:SolidMolecular weight:479.43OTS447
CAS:<p>OTS447 is a potent FLT3 inhibitor (IC50: 21 nM) with potential anticancer activity for cancer research .</p>Formula:C27H32ClN3O2Purity:98.78%Color and Shape:SolidMolecular weight:466.02Vepafestinib
CAS:<p>Vepafestinib is a RET inhibitor with potential antineoplastic activity[1].</p>Formula:C26H30N6O3Purity:98.56%Color and Shape:SolidMolecular weight:474.55UniPR505
CAS:<p>UniPR505 is a potent EphA2 antagonist (IC50: 0.95 µM), a novel 3α-carbamoyloxy derivative with antiangiogenic properties.</p>Formula:C39H57N3O5Purity:98.23%Color and Shape:SolidMolecular weight:647.89KB SRC 4
CAS:KB SRC 4 is a selective and potent c-Src inhibitor with antitumour activity that inhibits the growth of cancer cells.CAS 번호13460-73-83-4Formula:C32H23ClN8Purity:98.83% - 99.34%Color and Shape:SolidMolecular weight:555.03Brepocitinib
CAS:Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits JAK2/3 (IC50s: 77 nM/6.49 μM).Formula:C18H21F2N7OPurity:99.82%Color and Shape:SolidMolecular weight:389.4Axl/Mer/CSF1R-IN-2
CAS:<p>Axl/Mer/CSF1R-IN-2 (Comp 4) serves as an inhibitor for Axl, Mer, and CSF1R [1].</p>Formula:C24H22F3N5O5Color and Shape:SolidMolecular weight:517.46EGFR-IN-36
CAS:<p>EGFR-IN-36 inhibits EGFR, HER2, & mutants with IC50s: 19.09 nM (EGFR WT), 120.01 nM (HER2 WT), 2.35 nM (HER2 mutant).</p>Formula:C26H25ClN6O2Color and Shape:SolidMolecular weight:488.97EGFR-IN-71
CAS:<p>EGFR-IN-71 is a potent inhibitor of epidermal growth factor receptor (EGFR) (IC50= 3.7 μM). EGFR-IN-71 has research value in chordoma.</p>Formula:C16H9ClIN3Color and Shape:SolidMolecular weight:405.62EGFR-IN-74
<p>EGFR-IN-74 is a potent inhibitor targeting EGFR, specifically effective against the L858R/T790M mutations, exhibiting an IC50 value of 138 nM.</p>Formula:C32H28BrF3N6O4SColor and Shape:SolidMolecular weight:729.57PF-06459988
CAS:PF-06459988 is a novel, effective, orally active, irreversible, and selective epidermal growth factor receptor (EGFR) mutant inhibitor.Formula:C19H22ClN7O3Purity:98%Color and Shape:SolidMolecular weight:431.88EGFR-IN-29
CAS:<p>EGFR-IN-29 is a potent EGFR inhibitor.</p>Formula:C36H46BrN8O2PColor and Shape:SolidMolecular weight:733.68EGFR-IN-30
CAS:<p>EGFR-IN-30 is an EGFR inhibitor (IC50: 1-10 nM, <1 nM WT/mutants) with potential in cancer research.</p>Formula:C28H33BrN7O2PColor and Shape:SolidMolecular weight:610.49HER2-IN-5
CAS:<p>HER2-IN-5 is an effective inhibitor of orally active HER-2.</p>Formula:C27H33N7O3Color and Shape:SolidMolecular weight:503.6Nazartinib S-enantiomer
CAS:<p>Nazartinib is an EGFR inhibitor. Nazartinib S-enantiomer is the less active S-enantiomer of Nazartinib.</p>Formula:C26H31ClN6O2Purity:98%Color and Shape:SolidMolecular weight:495.02MS 154
CAS:<p>MS 154 is a potent PROTAC® targeting mutant EGFR in lung cancer, sparing WT-EGFR; effective in mice, with DC50 of 11-25 nM.</p>Formula:C46H54ClFN8O8Color and Shape:SolidMolecular weight:901.42TL02-59
CAS:<p>TL02-59: Fgr inhibitor (IC50=0.03nM), also targets Lyn (0.1nM), Hck (160nM), halts acute myelogenous leukemia growth.</p>Formula:C32H34F3N5O4Purity:98.77%Color and Shape:SolidMolecular weight:609.64FGFR3-IN-6
CAS:<p>FGFR3-IN-6 is a potent, selective inhibitor of FGFR 3, exhibiting an IC50 value of less than 350 nM , and is utilized in cancer research [1].</p>Formula:C25H23FN8O2Purity:98%Color and Shape:SolidMolecular weight:486.5
