Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(114 products)
- CSF-1R(42 products)
- EGFR(572 products)
- Ephrin Receptor(23 products)
- FLT(91 products)
- Fibroblast Growth Factor Receptor (FGFR)(169 products)
- HER(5 products)
- Hck(3 products)
- IGF-1R(91 products)
- PDGFR(126 products)
- PYK2(7 products)
- Src(80 products)
- TAM Receptor(32 products)
- Tie-2(21 products)
- Trk receptor(59 products)
- Tyrosine Kinases(26 products)
- VEGFR(267 products)
- c-Fms(108 products)
- c-Kit(102 products)
- c-Met/HGFR(129 products)
- c-RET(51 products)
Show 13 more subcategories
Found 1357 products of "Tyrosine Kinase/Adaptors"
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EGFR-IN-32
CAS:<p>EGFR-IN-32, a potent EGFR blocker, shows promise for EGFR-mutated illnesses. (Patent WO2021185297A1, compound 2)</p>Formula:C31H34N6O3Color and Shape:SolidMolecular weight:538.64Labuxtinib
CAS:<p>Labutinib is a selective inhibitor of the c-kit tyrosine kinase [1].</p>Formula:C20H16FN5O2Purity:99.77%Color and Shape:SolidMolecular weight:377.37c-Fms-IN-14
CAS:<p>c-Fms-IN-14 (Example 76) is a potent inhibitor of the c-Fms kinase with an IC50 of 4 nM, utilized in cancer and autoimmune disease research [1].</p>Formula:C26H24N6OPurity:98%Color and Shape:SolidMolecular weight:436.51AXL-IN-15
CAS:<p>AXL-IN-15 (cpd391) is a potent inhibitor of Axl, exhibiting both a dissociation constant (K i) and a half-maximal inhibitory concentration (IC50) of less than 1</p>Formula:C26H32F3N9O3Purity:98%Color and Shape:SolidMolecular weight:575.59UniPR1447
CAS:<p>UniPR1447 is a dual antagonist for both EphA2 and EphB2 receptors, exhibiting an IC50 value of 6.6 μM against EphA2-ephrin-A1 binding [1].</p>Formula:C36H50N2O4Purity:98%Color and Shape:SolidMolecular weight:574.79BEBT-109
CAS:<p>BEBT-109 is a selective epidermal growth factor receptor (EGFR) inhibitor that shows anti-tumor activity in EGFR-mutant non-small cell lung cancer.</p>Formula:C27H32N8O3Purity:97.26%Color and Shape:SolidMolecular weight:516.6EGFR-IN-33
CAS:<p>EGFR-IN-33, a low-toxicity acrylamide, inhibits EGFR, aiding against cancer, especially NSCLC (from WO2021185348A1, comp. 13).</p>Formula:C26H25ClN6O2Color and Shape:SolidMolecular weight:488.97FGFR4-IN-16
CAS:<p>FGFR4-IN-16 (CY-15-2) is a covalent inhibitor targeting FGFR-4, utilized in cancer research [1].</p>Formula:C35H30Cl2N6O5Purity:98%Color and Shape:SolidMolecular weight:685.56TRK-IN-24
CAS:<p>TRK-IN-24 (compound 10g) is a selective inhibitor of Trk receptors, effectively targeting TRKA, TRKC, and mutant forms TRKA G595R, TRKA G667C, and TRKA F589L,</p>Formula:C39H45N7O3Purity:98%Color and Shape:SolidMolecular weight:659.82BPIQ-I
CAS:<p>BPIQ-I (PD 159121), an ATP-competitive EGFR tyrosine kinase inhibitor, exhibits potent anti-proliferative activity.</p>Formula:C16H12BrN5Color and Shape:SolidMolecular weight:354.2VEGFR-2-IN-37
CAS:<p>VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.</p>Formula:C18H16N2O2SPurity:98%Color and Shape:SolidMolecular weight:324.4BT424
CAS:BT424, a specific HCK inhibitor, modulates macrophage activation and autophagy in vitro, and mitigates inflammation and renal fibrosis in the UUO model [1].Formula:C22H15BCl2N2O2Purity:98%Color and Shape:SolidMolecular weight:421.08Cinsebrutinib
CAS:<p>Cinsebrutinib, a Bruton's tyrosine kinase inhibitor, holds potential for research in cancer treatment.</p>Formula:C22H26FN3O2Purity:98%Color and Shape:SolidMolecular weight:383.46FGFR3-IN-7
CAS:<p>FGFR3-IN-7 is a potent, selective inhibitor of FGFR 3, demonstrating an IC50 value of less than 350 nM , and is utilized in cancer research [1].</p>Formula:C25H24FN9OPurity:98%Color and Shape:SolidMolecular weight:485.52Resigratinib
CAS:<p>Resigratinib (KIN-3248) is an oral, irreversible pan-FGFR family protein inhibitor, covalently binds to and inhibits all four FGFR isoforms(FGFR1/2/3/4).</p>Formula:C26H27F2N7O3Purity:98.58%Color and Shape:SolidMolecular weight:523.53Terevalefim
CAS:Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor.Formula:C9H8N2SPurity:99.8%Color and Shape:SolidMolecular weight:176.24VEGFR2-IN-3
CAS:<p>VEGFR2-IN-3 (compound 385) is a potent inhibitor of VEGFR2 [1].</p>Formula:C26H28ClN5O4Purity:98%Color and Shape:SolidMolecular weight:509.98ARRY-382
CAS:<p>ARRY-382 is a highly selective oral inhibitor of CSF-1R with an IC50 of 9 nM.</p>Formula:C32H36N8O2Purity:99.76%Color and Shape:SolidMolecular weight:564.68Lifirafenib
CAS:<p>Lifirafenib (Beigene-283) is a potent inhibitor of RAF family kinases and EGFR in biochemical assays with IC50 of 23, 29 and 495 nM for the recombinant</p>Formula:C25H17F3N4O3Purity:98% - 98.25%Color and Shape:SolidMolecular weight:478.42Simotinib
CAS:Simotinib (AL-6802) is an EGFR tyrosine kinase inhibitor (IC50 : 19.9 nM) with antitumour activity for the study of non-small cell lung cancer.Formula:C25H26ClFN4O4Purity:99.7%Color and Shape:SolidMolecular weight:500.95
