Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
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Subcategories of "Tyrosine Kinase/Adaptors"
ALK
CSF-1R
EGFR
Ephrin Receptor
FLT
Fibroblast Growth Factor Receptor (FGFR)
HER
Hck
IGF-1R
PDGFR
PYK2
Src
TAM Receptor
Tie-2
Trk receptor
Tyrosine Kinases
VEGFR
c-Fms
c-Kit
c-Met/HGFR
c-RET
Show 13 more subcategories
Products of "Tyrosine Kinase/Adaptors"
Crizotinib hydrochloride
CAS:1415560-69-8
Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of …
Formula:
C21H23Cl3FN5O
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
486.8
Ref: TM-T8399
| 5mg | 36.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 98.00 € | ||
| 100mg | 135.00 € | ||
| 200mg | 168.00 € | ||
| 500mg | 222.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Danusertib
CAS:827318-97-8
Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.
Formula:
C26H30N6O3
Purity:
98% - 98.44%
Color and Shape:
White Powder
Molecular weight:
474.55
Ref: TM-T2094
| 1mg | 59.00 € | ||
| 2mg | 83.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 359.00 € | ||
| 50mg | 546.00 € | ||
| 100mg | 779.00 € | ||
| 500mg | 1,574.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PQ401 hydrochloride (196868-63-0(free base))
PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM.
Formula:
C18H17Cl2N3O2
Purity:
99.9%
Color and Shape:
Solid
Molecular weight:
378.25
Ref: TM-T4324
| 2mg | 35.00 € | ||
| 5mg | 47.00 € | ||
| 10mg | 61.00 € | ||
| 25mg | 96.00 € | ||
| 50mg | 173.00 € | ||
| 100mg | 277.00 € | ||
| 200mg | 402.00 € | ||
| 1mL*10mM (DMSO) | 61.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Nintedanib esylate
CAS:656247-18-6
Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and …
Formula:
C31H33N5O4·C2H6O3S
Purity:
99.43% - 99.96%
Color and Shape:
Solid
Molecular weight:
649.76
Ref: TM-T5001
| 5mg | 42.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 70.00 € | ||
| 50mg | 83.00 € | ||
| 100mg | 103.00 € | ||
| 200mg | 161.00 € | ||
| 500mg | 310.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SGI-7079
CAS:1239875-86-5
SGI-7079: selective Axl inhibitor; hinders tumor growth dose-dependently; may target EGFR inhibitor resistance.
Formula:
C26H26FN7
Purity:
95.05% - 99.26%
Color and Shape:
Solid
Molecular weight:
455.53
Ref: TM-T6982
| 2mg | 41.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 237.00 € | ||
| 100mg | 346.00 € | ||
| 500mg | 807.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
FIIN-2
CAS:1633044-56-0
FIIN-2, an irreversible, pan-FGFR inhibitor, inhibits FGFR1/2/3/4 with IC50 of 3.09 nM, 4.3 nM, 27 …
Formula:
C35H38N8O4
Purity:
99.34% - 99.65%
Color and Shape:
Crystalline Solid
Molecular weight:
634.73
Ref: TM-T6836
| 1mg | 41.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 197.00 € | ||
| 50mg | 299.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(E)-AG 556
CAS:133550-41-1
AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.
Formula:
C20H20N2O3
Purity:
99.48%
Color and Shape:
Light Yellow Powder
Molecular weight:
336.38
Ref: TM-T21853
| 5mg | 36.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 146.00 € | ||
| 100mg | 226.00 € | ||
| 200mg | 333.00 € | ||
| 1mL*10mM (DMSO) | 41.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NSC 228155
CAS:113104-25-9
NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and …
Formula:
C11H6N4O4S
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
290.25
Ref: TM-T6908
| 5mg | 50.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 215.00 € | ||
| 100mg | 373.00 € | ||
| 200mg | 484.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Afatinib Dimaleate
CAS:850140-73-7
Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR …
Formula:
C32H33ClFN5O11
Purity:
100% - 99.66%
Color and Shape:
Solid
Molecular weight:
718.08
Ref: TM-T1773
| 1g | 460.00 € | ||
| 5mg | 40.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 105.00 € | ||
| 100mg | 138.00 € | ||
| 200mg | 184.00 € | ||
| 500mg | 308.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZD3229
CAS:2248003-60-1
AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors.
Formula:
C24H26FN7O3
Purity:
98.83%
Color and Shape:
Solid
Molecular weight:
479.51
Ref: TM-T5409
| 1mg | 43.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 136.00 € | ||
| 25mg | 239.00 € | ||
| 50mg | 352.00 € | ||
| 100mg | 491.00 € | ||
| 200mg | 674.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Mubritinib
CAS:366017-09-6
Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.
Formula:
C25H23F3N4O2
Purity:
99.85% - 99.87%
Color and Shape:
Solid
Molecular weight:
468.47
Ref: TM-T6124
| 5mg | 189.00 € | ||
| 10mg | 287.00 € | ||
| 25mg | 544.00 € | ||
| 50mg | 772.00 € | ||
| 100mg | 1,270.00 € | ||
| 1mL*10mM (DMSO) | 270.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
1-Naphthyl PP1 hydrochloride
CAS:956025-47-1
1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-Src
Formula:
C19H20ClN5
Purity:
98.63%
Color and Shape:
Solid
Molecular weight:
353.85
Ref: TM-T7371
| 5mg | 44.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 186.00 € | ||
| 100mg | 287.00 € | ||
| 200mg | 415.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
c-Kit-IN-1
CAS:1225278-16-9
c-Kit-IN-1 (DCC-2618) is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).
Formula:
C26H21F2N5O3
Purity:
98.16% - 98.72%
Color and Shape:
Solid
Molecular weight:
489.47
Ref: TM-T4332
| 1mg | 45.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 301.00 € | ||
| 50mg | 536.00 € | ||
| 100mg | 768.00 € | ||
| 500mg | 1,568.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ki20227
CAS:623142-96-1
Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).
Formula:
C24H24N4O5S
Purity:
97.16% - 99.37%
Color and Shape:
Solid
Molecular weight:
480.54
Ref: TM-T4315
| 1mg | 46.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 152.00 € | ||
| 25mg | 279.00 € | ||
| 50mg | 458.00 € | ||
| 100mg | 730.00 € | ||
| 200mg | 994.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Nampt-IN-1
CAS:1698878-14-6
Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with …
Formula:
C20H25N3O5S
Purity:
96.82% - 99.4%
Color and Shape:
Solid
Molecular weight:
419.49
Ref: TM-T4376
| 1mg | 39.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 134.00 € | ||
| 25mg | 253.00 € | ||
| 50mg | 423.00 € | ||
| 100mg | 625.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Alectinib hydrochloride
CAS:1256589-74-8
Alectinib hydrochloride (RO5424802 Hydrochloride) is a selective, and orally available inhibitor of ALK( IC50 : …
Formula:
C30H35ClN4O2
Purity:
99.61% - 99.96%
Color and Shape:
Solid
Molecular weight:
519.08
Ref: TM-T8387
| 5mg | 43.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 84.00 € | ||
| 50mg | 96.00 € | ||
| 100mg | 159.00 € | ||
| 500mg | 369.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ALW-II-41-27
CAS:1186206-79-0
ALW-II-41-27 (Eph receptor tyrosine kinase inhibitor), an Eph receptor tyrosine kinase inhibitor, is used for …
Formula:
C32H32F3N5O2S
Purity:
97.01% - 99.52%
Color and Shape:
Solid
Molecular weight:
607.69
Ref: TM-T4344
| 1mg | 68.00 € | ||
| 2mg | 95.00 € | ||
| 5mg | 172.00 € | ||
| 10mg | 258.00 € | ||
| 25mg | 427.00 € | ||
| 50mg | 629.00 € | ||
| 100mg | 889.00 € | ||
| 1mL*10mM (DMSO) | 239.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Dacomitinib
CAS:1110813-31-4
Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, …
Formula:
C24H25ClFN5O2
Purity:
100% - 99.34%
Color and Shape:
Solid
Molecular weight:
469.94
Ref: TM-T2483
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 348.00 € | ||
| 200mg | 435.00 € | ||
| 500mg | 717.00 € | ||
| 1mL*10mM (DMSO) | 79.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LDC1267
CAS:1361030-48-9
LDC1267 is a excellently specific TAM(Tyro3, Axl and Mer) kinase inhibitor, for Mer( IC50<5 …
Formula:
C30H26F2N4O5
Purity:
99.42% - 99.76%
Color and Shape:
Solid
Molecular weight:
560.55
Ref: TM-T2311
| 1mg | 35.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 248.00 € | ||
| 100mg | 417.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ruxolitinib (S enantiomer)
CAS:941685-37-6
Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective …
Formula:
C17H18N6
Purity:
99.5% - 99.79%
Color and Shape:
Solid
Molecular weight:
306.36
Ref: TM-T6156
| 5mg | 63.00 € | ||
| 10mg | 74.00 € | ||
| 50mg | 113.00 € | ||
| 100mg | 151.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
