Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(135 products)
- CSF-1R(42 products)
- EGFR(553 products)
- Ephrin Receptor(25 products)
- FLT(86 products)
- Fibroblast Growth Factor Receptor (FGFR)(176 products)
- HER(5 products)
- Hck(3 products)
- IGF-1R(97 products)
- PDGFR(127 products)
- PYK2(7 products)
- Src(82 products)
- TAM Receptor(33 products)
- Tie-2(20 products)
- Trk receptor(54 products)
- Tyrosine Kinases(12 products)
- VEGFR(236 products)
- c-Fms(100 products)
- c-Kit(113 products)
- c-Met/HGFR(140 products)
- c-RET(60 products)
Show 13 more subcategories
Found 1015 products of "Tyrosine Kinase/Adaptors"
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MS 154N
CAS:MS 154N is a negative control for MS 154, binds WT/L858R EGFR tightly (Kd 3-4.3nM), doesn't trigger mutant EGFR degradation.Formula:C47H56ClFN8O8Color and Shape:SolidMolecular weight:915.45Tyrphostin 51
CAS:Tyrphostin 51 is an effective inhibitor of EGFR kinase.Formula:C13H8N4O3Purity:98%Color and Shape:SolidMolecular weight:268.23EGFR-IN-39
CAS:EGFR-IN-39, an acrylamide, is a potent EGFR inhibitor and antitumor agent targeting NSCLC with low toxicity. See WO2021185348A1 for details.Formula:C24H25ClN6O3Color and Shape:SolidMolecular weight:480.95EGFR-IN-54
CAS:EGFR-IN-54 (Compound 3c) is a potent inhibitor of EGFR (IC50: 1.623 μM) and is toxic to cancer cells.Formula:C17H14N4O4S3Color and Shape:SolidMolecular weight:434.51JNJ28871063 hydrochloride
CAS:ErbB receptor family inhibitorFormula:C24H28Cl2N6O3Purity:98%Color and Shape:SolidMolecular weight:519.42Syk-IN-3
CAS:Syk-IN-3 is a Syk inhibitor with potential anti-inflammatory and anticancer activity and can be used to study immune dysregulation.
Formula:C24H28N4O3SPurity:97.29% - >99.99%Color and Shape:SolidMolecular weight:452.57EGFR-IN-64
CAS:EGFR-IN-64 inhibits EGFR with 0.33 μM IC50, showing promising anticancer properties.Formula:C20H21N3O3Color and Shape:SolidMolecular weight:351.4SDZ281-977
CAS:SDZ 281-977 is a derivative of Lavendustin A which is the EGF receptor tyrosine kinase inhibitor.Formula:C18H20O5Purity:99.64%Color and Shape:SolidMolecular weight:316.35GSK-2250665A
CAS:GSK-2250665A is an (Itk) inhibitor (pKi 9.2) with selectivity over Aurora B and Btk, inhibiting IFNγ in PBMCs for T-cell signaling studies.Formula:C26H29N5OSPurity:99.38%Color and Shape:SolidMolecular weight:459.61EGFR-IN-25
CAS:EGFR-IN-25, an efficacious EGFR inhibitor, demonstrates IC50 values of 9 nM for BaF3 cells (EGFR DEL19/T790M/C797S) and 60 nM for A431 cells (WT), respectively.Formula:C34H43N9O2Color and Shape:SolidMolecular weight:609.76Rp-cAMPS triethylammonium salt
CAS:Rp-cAMPS triethylammonium salt is a competitive inhibitor of cAMP-dependent protein kinase I and II.Formula:C16H27N6O5PSPurity:98%Color and Shape:SolidMolecular weight:446.46PF-4618433
CAS:PF-4618433 is a selective PYK2 inhibitor with osteogenic activity.Formula:C24H27N7O2Purity:99.95%Color and Shape:SolidMolecular weight:445.52Ref: TM-T22397
2mg77.00€5mg114.00€10mg177.00€25mg371.00€50mg612.00€100mg982.00€200mg1,333.00€1mL*10mM (DMSO)126.00€c-Kit-IN-2
CAS:c-Kit-IN-2 is a c-KIT inhibitor (IC50: 82 nM), shows superior antiproliferative activities against all the three GIST cell lines, GIST430, GIST882, and GIST48 (Formula:C25H29N9O2SPurity:98%Color and Shape:SolidMolecular weight:519.62JBJ-09-063 hydrochloride
JBJ-09-063 hydrochloride: targeted EGFR inhibitor, effective for various mutations and TKI-resistant lung cancer models.Formula:C31H30ClFN4O3SColor and Shape:SolidMolecular weight:593.11EGFR-IN-21
CAS:EGFR-IN-21, a potent EGFR inhibitor, exhibits an IC50 of 0.38 nM, demonstrating significant antitumor activity.Formula:C36H44BrN10O2PColor and Shape:SolidMolecular weight:759.68RTC-5
CAS:RTC-5 (TRC-382) is a phenothiazine compound that has been specifically enhanced for its potent anti-cancer properties.Formula:C24H22ClF3N2O3SPurity:98.14%Color and Shape:SolidMolecular weight:510.96Ref: TM-T12777
2mg35.00€5mg52.00€10mg78.00€25mg149.00€50mg235.00€100mg376.00€200mg550.00€1mL*10mM (DMSO)55.00€BIBX 1382 Dihydrochloride
CAS:BIBX 1382 Dihydrochloride blocks Lassa/Ebola entry, aids in studying virus-host interactions, and hints at kinase targets for therapy.Formula:C18H21Cl3FN7Color and Shape:SolidMolecular weight:460.76Limertinib
CAS:Limertinib (ASK120067) is a EGFR tyrosine kinase inhibitor targeting EGFR T790M, applicable for the study of non-small cell lung cancer.
Formula:C29H32ClN7O2Purity:97.44%Color and Shape:SolidMolecular weight:546.06Mutated EGFR-IN-2
CAS:Mutated EGFR-IN-2 is an inhibitor of mutant-selective EGFR.Formula:C29H35FN8O3Purity:98%Color and Shape:SolidMolecular weight:562.64EGFR-IN-28
CAS:EGFR-IN-28 is a potent EGFR inhibitor. EGFR-IN-28 has antitumor activity .Formula:C31H39BrN10O3SColor and Shape:SolidMolecular weight:711.68
