Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(133 products)
- CSF-1R(42 products)
- EGFR(591 products)
- Ephrin Receptor(25 products)
- FLT(90 products)
- Fibroblast Growth Factor Receptor (FGFR)(182 products)
- HER(3 products)
- Hck(3 products)
- IGF-1R(104 products)
- PDGFR(129 products)
- PYK2(7 products)
- Src(82 products)
- TAM Receptor(34 products)
- Tie-2(20 products)
- Trk receptor(57 products)
- Tyrosine Kinases(24 products)
- VEGFR(245 products)
- c-Fms(112 products)
- c-Kit(116 products)
- c-Met/HGFR(139 products)
- c-RET(61 products)
Show 13 more subcategories
Found 1135 products of "Tyrosine Kinase/Adaptors"
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EGFR-IN-87
CAS:EGFR-IN-87 is an EGFR tyrosine kinase inhibitor with potent inhibitory activity, exhibiting IC50 values of 3.1 nM, 1.3 nM, and 7.1 nM against EGFR_d746-750,Formula:C28H33N7O2Purity:98.64%Color and Shape:SolidMolecular weight:499.61Ropsacitinib
CAS:Ropsacitinib (PF-06826647) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain (IC50: 17 nM).Formula:C20H17N9Purity:99.87%Color and Shape:SolidMolecular weight:383.41CH6953755
CAS:CH6953755: oral YES1 kinase inhibitor, IC50 1.8 nM, potent, selective, anticancer, halts cell proliferation.Formula:C26H22F2N6O4SPurity:98.87%Color and Shape:SolidMolecular weight:552.55Ref: TM-T10784
1mg58.00€5mg123.00€10mg187.00€25mg366.00€50mg588.00€100mg944.00€1mL*10mM (DMSO)149.00€EGFR/ErbB-2 inhibitor-1
CAS:EGFR/ErbB-2 inhibitor-1 is a selective ErbB2/HER2 inhibitor that effectively blocks ErbB2 and HER2 signaling.Formula:C23H15ClFN3OS2Purity:98.93%Color and Shape:SolidMolecular weight:467.97Sevabertinib
CAS:Sevabertinib (BAY 2927088) is an EGFR tyrosine kinase inhibitor, with anticancer activity, used in research on non-small cell lung cancer.Formula:C24H25ClN4O5Purity:99.81%Color and Shape:SolidMolecular weight:484.93MK-2461
CAS:MK-2461 is a novel inhibitor that targets multiple proteins and competitively binds to ATP sites, specifically inhibiting the activated c-Met protein with anFormula:C24H25N5O5SPurity:95.41% - 99.67%Color and Shape:SolidMolecular weight:495.55Ref: TM-T6094
1mg50.00€5mg114.00€10mg177.00€25mg344.00€50mg523.00€100mg798.00€200mg1,071.00€1mL*10mM (DMSO)127.00€FIIN-1
CAS:FIIN-1 (FGFR irreversible inhibitor-1) is an irreversible and selective FGFR inhibitor with Kd of 2.8, 6.9, 5.4, 120, 32 and 120 nM for FGFR1, FGFR2, FGFR3,Formula:C32H39Cl2N7O4Purity:98.75%Color and Shape:SolidMolecular weight:656.6Ref: TM-T37426
1mg79.00€2mg103.00€5mg202.00€10mg329.00€25mg550.00€50mg783.00€100mg1,035.00€500mg2,118.00€Tyrphostin AG 538
CAS:Tyrphostin AG 538 is a chalcone compound, an IGF-1 receptor kinase inhibitor (IC₅0 : for 400 nM) that is potent, cell-permeable, reversible, and competitive.Formula:C16H11NO5Purity:98.75%Color and Shape:SoildMolecular weight:297.26Zidesamtinib
CAS:Zidesamtinib (NVL-520) is a ROS1 fusion and resistance mutation inhibitor that inhibits ROS1 and can be used to study non-small cell lung cancer.Formula:C22H22FN7OPurity:99.74%Color and Shape:SolidMolecular weight:419.455Ref: TM-T72953
1mg71.00€5mg152.00€10mg236.00€25mg480.00€50mg767.00€100mg1,224.00€200mg1,648.00€1mL*10mM (DMSO)167.00€EGFR-IN-1 hydrochloride
CAS:EGFR-IN-1 HCl targets L858R/T790M EGFR mutants over wild-type; IC50: 4 nM in H1975, 28 nM in mutant HCC827 cells.Formula:C28H31ClN6O4Purity:99.16%Color and Shape:SolidMolecular weight:551.04Ref: TM-T11157L
1mg62.00€5mg142.00€10mg205.00€25mg319.00€50mg429.00€100mg587.00€200mg795.00€1mL*10mM (DMSO)190.00€BTK inhibitor 1
CAS:BTK inhibitor 1 (Compound 27) is a BTK inhibitor (IC50: 0.11 nM) with an inhibitory effect on B-cell activation in hWB with an IC50 of 2 nM.
Formula:C24H23FN8O2Purity:98.24% - 98.91%Color and Shape:SolidMolecular weight:474.49EGFR-IN-8
CAS:EGFR-IN-8, a dual inhibitor targeting both EGFR and c-Met, shows potential as a promising candidate for further development in treating EGFR TKI-resistant NSCLC
Formula:C32H23ClF3N7O4Purity:99.51%Color and Shape:SolidMolecular weight:662.02AZ-23
CAS:AZ-23 is an inhibitor of ATP-competitive and Trk kinase A/B/C.Formula:C17H19ClFN7OPurity:99.4%Color and Shape:SolidMolecular weight:391.83Src Inhibitor 3
CAS:Src Inhibitor 3 blocks c-Src kinase (IC50 <3 nM CSK HTRF, <4 nM Caliper), boosting T cell growth from receptor signals.Formula:C34H32ClFN8O4Purity:98.35%Color and Shape:SolidMolecular weight:671.12Ref: TM-T13000
1mg92.00€5mg187.00€10mg320.00€25mg507.00€50mg702.00€100mgTo inquire1mL*10mM (DMSO)279.00€EGFR-IN-34
EGFR-IN-34 is a low-toxicity, acrylamide derivative antitumor agent that is a potent inhibitor of EGFR.Formula:C26H27ClN6O2Color and Shape:SolidMolecular weight:490.98EGFR-IN-126
CAS:EGFR-IN-126 (compound 9d) is an effective inhibitor of EGFR L858R/T790M/C797S, displaying an IC50 value of 0.005 μM. It exhibits antitumor activity both in vivo and in vitro.Formula:C28H28BrFN4O3Color and Shape:SolidMolecular weight:567.45HER2-IN-6
CAS:HER2-IN-6, a potent HER2 inhibitor, may target wild/mutant EGFR and HER2-mediated tumors. (Patent WO2021164697A1, compound 11)Formula:C26H32N8O3Color and Shape:SolidMolecular weight:504.58EGFR-IN-24
EGFR-IN-24 is a potent inhibitor of EGFR and inhibits EGFR (del19/T790M/C797S) and EGFR (L858R/T790M/C797S).Formula:C30H35FN6O3Color and Shape:SolidMolecular weight:546.64EGFR-IN-18
EGFR-IN-18 strongly inhibits L858R/T790M/C797S mutant EGFR (4.9 nM) and also targets wild-type EGFR (47 nM).Formula:C33H28N6O3SColor and Shape:SolidMolecular weight:588.68BML-265
CAS:BML-265 is a potent inhibitor of EGFR tyrosine kinase (EGFR tyrosine kinase). It disrupts Golgi apparatus integrity in human cells and hinders the transport of secretory proteins across various substances. In contrast, BML-265 does not affect the integrity and transport of the Golgi apparatus in rodent cells.Formula:C18H15N3O2Color and Shape:SolidMolecular weight:305.331
