Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(135 products)
- CSF-1R(42 products)
- EGFR(553 products)
- Ephrin Receptor(25 products)
- FLT(88 products)
- Fibroblast Growth Factor Receptor (FGFR)(176 products)
- HER(5 products)
- Hck(3 products)
- IGF-1R(97 products)
- PDGFR(127 products)
- PYK2(7 products)
- Src(82 products)
- TAM Receptor(33 products)
- Tie-2(20 products)
- Trk receptor(53 products)
- Tyrosine Kinases(13 products)
- VEGFR(236 products)
- c-Fms(100 products)
- c-Kit(113 products)
- c-Met/HGFR(138 products)
- c-RET(60 products)
Show 13 more subcategories
Found 1017 products of "Tyrosine Kinase/Adaptors"
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Tyrphostin A25
CAS:Tyrphostin A25 (Tyrphostin AG 82) is a specific EGFR tyrosine kinase inhibitor and GPR35 agonist with an IC50 value of 0.94 μM for GPR35 and an EC50 value of 5.Formula:C10H6N2O3Purity:98.98%Color and Shape:Yellow Green Powder /Off-White SolidMolecular weight:202.17A-935142
CAS:A-935142 enhances hERG (Kv 11.1) channels, slows inactivation, promotes activation, and shortens repolarization.Formula:C18H19F3N2O2Purity:98.97% - 99.91%Color and Shape:SolidMolecular weight:352.35LY 456236 hydrochloride
CAS:LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM.Formula:C16H16ClN3O2Purity:99.95%Color and Shape:SolidMolecular weight:317.77PD 174265
CAS:PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.Formula:C17H15BrN4OPurity:99.51%Color and Shape:SolidMolecular weight:371.23EMI1
CAS:EMI1 targets mutated EGFR in drug-resistant NSCLC research.Formula:C20H18N2O3Purity:99.96%Color and Shape:SolidMolecular weight:334.37Cloperastine fendizoate
CAS:Cloperastine fendizoate (Hustazol) inhibits the hERG K+ currents in a concentration-dependent manner (IC50: 27 nM).Formula:C40H38ClNO5Purity:99.97%Color and Shape:SolidMolecular weight:648.19Epitinib succinate
CAS:Epitinib succinate (HMPL-813 succinate) is an orally active and brain penetration EGFR tyrosine kinase inhibitor and can be used in studies about cancer.Formula:C28H32N6O6Purity:98.02% - 99.79%Color and Shape:SolidMolecular weight:548.59Ref: TM-T35914
1mg75.00€2mg97.00€5mg170.00€10mg271.00€25mg449.00€50mg615.00€100mg843.00€500mg1,691.00€RET-IN-3
CAS:RET-IN-3 is a RETV804M kinase inhibitor with potential anticancer activity for the study of non-small cell lung cancer.Formula:C18H21N5O2Purity:99.52%Color and Shape:SolidMolecular weight:339.39Ref: TM-T9673
1mg73.00€5mg158.00€10mg240.00€25mg452.00€50mg712.00€100mg1,093.00€200mg1,473.00€1mL*10mM (DMSO)168.00€CSF1R-IN-3
CAS:CSF1R-IN-3 is an orally effective CSF-1R inhibitor with an IC50 value of 2.1 nM.Formula:C30H38N8O4Purity:98.4%Color and Shape:SolidMolecular weight:574.67Ref: TM-T64066
1mg101.00€5mg245.00€10mg358.00€25mg665.00€50mg973.00€100mg1,395.00€1mL*10mM (DMSO)309.00€EGFR-IN-99
CAS:EGFR-IN-99 (JBJ-03-142-02) is an EGFR and HER2 Exon 20 insertion mutation inhibitor for the study of non-small cell lung cancer (NSCLC).Formula:C25H22FN7O3Purity:97.75%Color and Shape:SolidMolecular weight:487.49EGFR-IN-9
CAS:EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M).Formula:C29H24N4O3Purity:99.8%Color and Shape:SolidMolecular weight:476.53Falnidamol
CAS:Falnidamol (BIBX 1382), an oral selective EGFR inhibitor, IC50 3 nM, weak on ErbB2 and others, anti-cancer pyrimido-pyrimidine.Formula:C18H19ClFN7Purity:98.816%Color and Shape:SolidMolecular weight:387.84Ref: TM-TQ0271
2mg39.00€5mg60.00€10mg96.00€25mg182.00€50mg318.00€100mg439.00€200mg612.00€1mL*10mM (DMSO)60.00€PKI-166
CAS:PKI-166: oral EGF-R tyrosine kinase inhibitor (IC50: 0.7 nM), halts growth & spread of many human cancers, including pancreatic.Formula:C20H18N4OPurity:99.2%Color and Shape:SolidMolecular weight:330.38Ref: TM-T16549
2mg39.00€5mg75.00€10mg111.00€25mg215.00€50mg358.00€100mg572.00€200mg767.00€1mL*10mM (DMSO)84.00€ML 315
CAS:ML 315 is a selective Clk and DYRK inhibitor with potential anticancer activity for the study of neurological disorders.Formula:C18H13Cl2N3O2Purity:99.08%Color and Shape:SolidMolecular weight:374.22c-Fms-IN-13
CAS:c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor (IC50= 17 nM). c-Fms-IN-13 is an anti-inflammatory agent.Formula:C22H26N4O2Purity:99.93% - 99.97%Color and Shape:SolidMolecular weight:378.47BT424
CAS:BT424, a specific HCK inhibitor, modulates macrophage activation and autophagy in vitro, and mitigates inflammation and renal fibrosis in the UUO model [1].Formula:C22H15BCl2N2O2Purity:98%Color and Shape:SolidMolecular weight:421.08BGB-102
CAS:BGB-102 (JNJ-26483327) is a kinase inhibitor targeting FLT3 and YES1 and an antagonist targeting EGFR and VEGFR3.Formula:C22H25BrN4O2Purity:99.02%Color and Shape:SolidMolecular weight:457.36EGFR-IN-33
CAS:EGFR-IN-33, a low-toxicity acrylamide, inhibits EGFR, aiding against cancer, especially NSCLC (from WO2021185348A1, comp. 13).Formula:C26H25ClN6O2Color and Shape:SolidMolecular weight:488.97c-met-IN-1
CAS:c-met-IN-1 is a potent and selective c-Met inhibitor (IC50: 1.1 nM) with antitumor activity.Formula:C35H37FN6O5Purity:98%Color and Shape:SolidMolecular weight:640.7HKI-357
CAS:HKI-357 irreversibly inhibits EGFR/ERBB2 (IC50: 34/33 nM), blocks EGFR Y1068 autophosphorylation, and AKT/MAPK phosphorylation.Formula:C31H29ClFN5O3Purity:99.91%Color and Shape:SolidMolecular weight:574.05Ref: TM-T11569
1mg62.00€2mgTo inquire5mg125.00€10mg188.00€25mg373.00€50mg540.00€100mg787.00€200mg1,035.00€1mL*10mM (DMSO)159.00€
