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Fibroblast Growth Factor Receptor (FGFR)

Fibroblast Growth Factor Receptor (FGFR)

FGFR inhibitors are targeted therapies that block the activity of fibroblast growth factor receptors (FGFRs), which are involved in cell proliferation, differentiation, and angiogenesis. FGFR signaling contributes to the formation of new blood vessels in tumors, promoting their growth and survival. Inhibiting FGFR can therefore reduce angiogenesis and tumor progression. At CymitQuimica, we provide a range of high-quality FGFR inhibitors to support your research in cancer, developmental biology, and angiogenesis.

Found 170 products of "Fibroblast Growth Factor Receptor (FGFR)"

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  • PD168393
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    PD168393

    CAS:
    <p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>
    Formula:C17H13BrN4O
    Purity:99.13% - 99.83%
    Color and Shape:Solid
    Molecular weight:369.22

    Ref: TM-T6932

  • Lenvatinib mesylate
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    Lenvatinib mesylate

    CAS:
    <p>Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.</p>
    Formula:C22H23ClN4O7S
    Purity:99.03% - 99.79%
    Color and Shape:Solid
    Molecular weight:522.96

    Ref: TM-T8541

  • SSR128129E
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    SSR128129E

    CAS:
    <p>SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other related RTKs.</p>
    Formula:C18H15N2O4·Na
    Purity:98.79% - ≥95%
    Color and Shape:Solid
    Molecular weight:346.31

    Ref: TM-T6082

  • H3B-6527
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    H3B-6527

    CAS:
    <p>H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma, with antineoplastic activity.</p>
    Formula:C29H34Cl2N8O4
    Purity:97.45%
    Color and Shape:Solid
    Molecular weight:629.54

    Ref: TM-T7738

  • Futibatinib
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    Futibatinib

    CAS:
    <p>Futibatinib (TAS-120) is an orally active, potent,and irreversible FGFR inhibitor of FGFR1, FGFR2, FGFR3, and FGFR4.Cost-effective and quality-assured.</p>
    Formula:C22H22N6O3
    Purity:97.66% - 99.44%
    Color and Shape:Solid
    Molecular weight:418.45

    Ref: TM-T5044

  • FGFR2-IN-3
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    FGFR2-IN-3

    CAS:
    <p>FGFR2-IN-3 is an orally active selective FGFR2 inhibitor[1].</p>
    Formula:C28H24FN7O2
    Purity:99.63%
    Color and Shape:Soild
    Molecular weight:509.53

    Ref: TM-T60185

  • TG 100801
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    TG 100801

    CAS:
    <p>TG 100801 is a dual inhibitor of VEGFr2 and Src family kinases and is a candidate compound for the treatment of age-related macular degeneration (AMD).</p>
    Formula:C33H30ClN5O3
    Purity:99.28% - 99.61%
    Color and Shape:Solid
    Molecular weight:580.08

    Ref: TM-T13157

  • CPL304110
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    CPL304110

    CAS:
    <p>CPL304110: oral, selective FGFR 1-3 inhibitor; IC50 - FGFR1: 0.75nM, FGFR2: 0.5nM, FGFR3: 3.05nM.</p>
    Formula:C25H30N6O2
    Color and Shape:Solid
    Molecular weight:446.54

    Ref: TM-T62652

  • FGFR3-IN-5
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    FGFR3-IN-5

    CAS:
    <p>FGFR3-IN-5: potent, selective FGFR3 inhibitor. IC50: 3 nM FGFR3, 44 nM FGFR2, 289 nM FGFR1. For cancer research.</p>
    Formula:C24H24FN7O3
    Color and Shape:Solid
    Molecular weight:477.49

    Ref: TM-T73146

  • MAX-40279 hydrochloride
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    MAX-40279 hydrochloride

    CAS:
    <p>MAX-40279 HCl: potent FLT3/FGFR inhibitor; potential in AML research.</p>
    Formula:C22H24ClFN6OS
    Color and Shape:Solid
    Molecular weight:474.98

    Ref: TM-T63094

  • MAX-40279 hemifumarate
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    MAX-40279 hemifumarate

    CAS:
    <p>MAX-40279 hemifumarate inhibits FLT3 and FGFR kinases, showing promise for AML treatment.</p>
    Formula:C48H50F2N12O6S2
    Color and Shape:Solid
    Molecular weight:993.12

    Ref: TM-T63916

  • FGFR4-IN-11
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    FGFR4-IN-11

    CAS:
    <p>FGFR4-IN-11: selective, covalent FGFR4 inhibitor; IC50=2.1 nM; blocks FGF19 pathway; anticancer.</p>
    Formula:C29H29N5O5
    Color and Shape:Solid
    Molecular weight:527.57

    Ref: TM-T63704

  • FGFR3-IN-1
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    FGFR3-IN-1

    CAS:
    <p>FGFR3-IN-1 (compound 1) is a fibroblast growth factor receptor (FGFR) inhibitor that inhibits FGFR1 (IC50: 40 nM), FGFR2 (IC50: 5.1 nM) and FGFR3 (IC50: 12 nM).</p>
    Formula:C28H39N9O3S
    Color and Shape:Solid
    Molecular weight:581.73

    Ref: TM-T64107

  • SSR128129E free acid
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    SSR128129E free acid

    CAS:
    <p>SSR128129E free acid is an orally available and allosteric inhibitor of FGFR(IC50 of 1.9 μM for FGFR1).</p>
    Formula:C18H16N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.33

    Ref: TM-T13003

  • FGFR4-IN-5
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    FGFR4-IN-5

    CAS:
    <p>FGFR4-IN-5: potent, selective FGFR4 inhibitor, IC50 6.5 nM, strong in vivo anti-tumor effect, for liver cancer research.</p>
    Formula:C23H23Cl2N5O5
    Color and Shape:Solid
    Molecular weight:520.37

    Ref: TM-T37425

  • FIIN-4
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    FIIN-4

    CAS:
    <p>FIIN-4 is a covalent inhibitor of FGFR and can be used in studies about metastatic breast cancer.</p>
    Formula:C35H38N8O4
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:634.73

    Ref: TM-T27319

  • FGFR-IN-9
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    FGFR-IN-9

    <p>FGFR-IN-9: oral FGFR inhibitor, IC50: 17.1 nM (FGFR4 WT), 29.6 (FGFR3), 30.7 (V550L), 46.7 (FGFR2), 64.3 nM (FGFR1).</p>
    Formula:C25H28N6O3S
    Color and Shape:Solid
    Molecular weight:492.59

    Ref: TM-T73316

  • FGFR-IN-3
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    FGFR-IN-3

    CAS:
    <p>FGFR-IN-3: potent, oral FGFR modulator, BBB-penetrating, neuroprotective, potential in neurodegeneration study.</p>
    Formula:C18H27F2N5O2
    Color and Shape:Solid
    Molecular weight:383.44

    Ref: TM-T61660

  • Derazantinib Racemate
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    Derazantinib Racemate

    CAS:
    <p>Derazantinib Racemate is an oral ATP competitive kinase inhibitor targeting FGFR1/2/3 (IC50s: 4.5/1.8/4.5 nM).</p>
    Formula:C29H29FN4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:468.57

    Ref: TM-T10997

  • SUN13837
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    SUN13837

    CAS:
    <p>SUN13837, an oral FGFR modulator, crosses the BBB and shows neuroprotective promise.</p>
    Formula:C21H29N5O2
    Color and Shape:Solid
    Molecular weight:383.49

    Ref: TM-T61666