c-Fms
c-Fms inhibitors target the Colony Stimulating Factor-1 Receptor (c-Fms), a tyrosine kinase involved in the regulation of macrophages and other immune cells. c-Fms signaling plays a role in the proliferation, differentiation, and survival of these cells. Dysregulation of c-Fms is associated with diseases such as cancer, inflammatory conditions, and osteoporosis. At CymitQuimica, we offer c-Fms inhibitors to support your research in immunology, oncology, and inflammatory diseases.
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CSF1R-IN-3
CAS:2760584-90-3
CSF1R-IN-3 is an orally effective CSF-1R inhibitor with an IC50 value of 2.1 nM.
Formula:
C30H38N8O4
Purity:
97.31%
Color and Shape:
Solid
Molecular weight:
574.67
Ref: TM-T64066
| 1mg | 102.00 € | ||
| 5mg | 248.00 € | ||
| 10mg | 362.00 € | ||
| 25mg | 672.00 € | ||
| 50mg | 983.00 € | ||
| 100mg | 1,411.00 € | ||
| 1mL*10mM (DMSO) | 313.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
c-Fms-IN-9
CAS:1628574-50-4
c-Fms-IN-9 inhibits c-FMS/uFMS and uKIT with IC50 <0.01μM and 0.1-1μM, from patent WO2014145023A1.
Formula:
C21H23N7O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
405.45
Ref: TM-T10648
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
c-Fms-IN-2
CAS:791587-67-2
c-Fms-IN-2 is an inhibitor of c-FMS kinase (IC50 = 24 nM).
Formula:
C19H21N3O3
Purity:
97.34%
Color and Shape:
Solid
Molecular weight:
339.39
Ref: TM-T10775
| 1mg | 95.00 € | ||
| 5mg | 249.00 € | ||
| 10mg | 367.00 € | ||
| 25mg | 550.00 € | ||
| 50mg | 775.00 € | ||
| 100mg | 1,040.00 € | ||
| 1mL*10mM (DMSO) | 188.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Sotuletinib dihydrochloride
CAS:2222138-40-9
Sotuletinib (BLZ945) dihydrochloride is an orally administered, blood-brain barrier-permeable inhibitor specifically targeting CSF1-R with an …
Formula:
C20H24Cl2N4O3S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
471.4
Ref: TM-T78603
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Pimicotinib
CAS:2253123-16-7
Pimicotinib (ABSK021) is a potent CSF1R inhibitor with antitumor activity and can be used to …
Formula:
C22H24N6O3
Purity:
99.8%
Color and Shape:
Solid
Molecular weight:
420.46
Ref: TM-T79157
| 1mg | 64.00 € | ||
| 5mg | 139.00 € | ||
| 10mg | 205.00 € | ||
| 25mg | 371.00 € | ||
| 50mg | 614.00 € | ||
| 100mg | 976.00 € | ||
| 500mg | 1,962.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
IACS-9439
CAS:2231259-57-5
IACS-9439 is a potent, selective, and orally active inhibitor of CSF1R, exhibiting a K(i) of …
Formula:
C23H26ClN7O3S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
516.02
Ref: TM-T69759
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
c-Fms-IN-13
CAS:885704-58-5
c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor (IC50= 17 nM). c-Fms-IN-13 is an …
Formula:
C22H26N4O2
Purity:
100% - 99.83%
Color and Shape:
Liquid
Molecular weight:
378.47
Ref: TM-T61589
| 5mg | 46.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 131.00 € | ||
| 50mg | 208.00 € | ||
| 100mg | To inquire |
Estimated delivery in United States, on Wednesday 22 Jan 2025
c-Fms-IN-1
CAS:885703-64-0
c-Fms-IN-1 is an inhibitor of c-FMS kinase (IC50 = 0.8 nM).
Formula:
C22H27N5O2
Purity:
99.88%
Color and Shape:
Solid
Molecular weight:
393.48
Ref: TM-T10643
| 2mg | 41.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 260.00 € | ||
| 100mg | 376.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
c-Fms-IN-6
CAS:1628574-81-1
c-Fms-IN-6 is a potent inhibitor of c-FMS (IC50 ≤10 nM for unphosphorylated c-FMS) and also …
Formula:
C22H25N7O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
419.48
Ref: TM-T10645
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Chiauranib
CAS:1256349-48-0
Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R …
Formula:
C27H21N3O3
Purity:
96.25%
Color and Shape:
Solid
Molecular weight:
435.47
Ref: TM-T35570
| 1mg | 89.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 300.00 € | ||
| 25mg | 508.00 € | ||
| 50mg | 732.00 € | ||
| 100mg | 1,003.00 € | ||
| 1mL*10mM (DMSO) | 213.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
c-Fms-IN-14
CAS:1898210-99-5
c-Fms-IN-14 (Example 76) is a potent inhibitor of the c-Fms kinase with an IC50 of …
Formula:
C26H24N6O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
436.51
Ref: TM-T79815
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 5 Feb 2025
