c-Fms
c-Fms inhibitors target the Colony Stimulating Factor-1 Receptor (c-Fms), a tyrosine kinase involved in the regulation of macrophages and other immune cells. c-Fms signaling plays a role in the proliferation, differentiation, and survival of these cells. Dysregulation of c-Fms is associated with diseases such as cancer, inflammatory conditions, and osteoporosis. At CymitQuimica, we offer c-Fms inhibitors to support your research in immunology, oncology, and inflammatory diseases.
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PLX647
CAS:873786-09-5
PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).
Formula:
C21H17F3N4
Purity:
99.38%
Color and Shape:
Solid
Molecular weight:
382.38
Ref: TM-T1925
| 2mg | 44.00 € | ||
| 5mg | 64.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated
CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with …
Color and Shape:
Solid
Molecular weight:
57.76 kDa (predicted); 82.52 kDa (reducing conditions)
Ref: TM-TMPY-06384
| 20µg | 465.00 € | ||
| 100µg | 1,054.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZ304
CAS:942507-42-8
AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and …
Formula:
C27H25N5O2
Purity:
99.83%
Color and Shape:
Solid
Molecular weight:
451.52
Ref: TM-T5172
| 10mg | 41.00 € | ||
| 25mg | 63.00 € | ||
| 50mg | 93.00 € | ||
| 100mg | 150.00 € | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PLX5622 hemifumarate
PLX5622 hemifumarate: selective CSF1R inhibitor (IC50: 0.016 μM, Ki: 5.9 nM), brain-penetrant, oral, clears microglia …
Formula:
C25H23F2N5O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
453.45
Ref: TM-T12505
| 200mg | 1,092.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Sotuletinib
CAS:953769-46-5
Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its …
Formula:
C20H22N4O3S
Purity:
97.43% - 99.82%
Color and Shape:
Solid
Molecular weight:
398.48
Ref: TM-T6119
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 169.00 € | ||
| 50mg | 213.00 € | ||
| 100mg | 370.00 € | ||
| 500mg | 848.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
OSI-930
CAS:728033-96-3
OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.
Formula:
C22H16F3N3O2S
Purity:
99.76%
Color and Shape:
Solid
Molecular weight:
443.44
Ref: TM-T2624
| 1mg | 51.00 € | ||
| 5mg | 100.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 259.00 € | ||
| 50mg | 419.00 € | ||
| 100mg | 605.00 € | ||
| 1mL*10mM (DMSO) | 100.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
cFMS Receptor Inhibitor II
CAS:959860-85-6
cFMS Receptor Inhibitor II is a CSF1R kinase inhibitor
Formula:
C23H20N4O
Purity:
99.80%
Color and Shape:
Solid
Molecular weight:
368.43
Ref: TM-T5586
| 1mg | 50.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 253.00 € | ||
| 50mg | 374.00 € | ||
| 100mg | 542.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PF 477736
CAS:952021-60-2
PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) …
Formula:
C22H25N7O2
Purity:
98% - 98.34%
Color and Shape:
Solid
Molecular weight:
419.48
Ref: TM-T6028
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Ki20227
CAS:623142-96-1
Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).
Formula:
C24H24N4O5S
Purity:
97.16% - 99.37%
Color and Shape:
Solid
Molecular weight:
480.54
Ref: TM-T4315
| 1mg | 46.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 152.00 € | ||
| 25mg | 279.00 € | ||
| 50mg | 458.00 € | ||
| 100mg | 730.00 € | ||
| 200mg | 994.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Pexidartinib
CAS:1029044-16-3
Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of …
Formula:
C20H15ClF3N5
Purity:
98.59% - 99.66%
Color and Shape:
Solid
Molecular weight:
417.81
Ref: TM-T2115
| 5mg | 53.00 € | ||
| 10mg | 67.00 € | ||
| 25mg | 99.00 € | ||
| 50mg | 124.00 € | ||
| 100mg | 156.00 € | ||
| 200mg | 204.00 € | ||
| 500mg | 345.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Pazopanib Hydrochloride
CAS:635702-64-6
Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in …
Formula:
C21H23N7O2S·HCl
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
473.98
Ref: TM-T6930
| 10mg | 52.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 95.00 € | ||
| 100mg | 139.00 € | ||
| 200mg | 225.00 € | ||
| 500mg | 355.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PRN1371
CAS:1802929-43-6
PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 …
Formula:
C26H30Cl2N6O4
Purity:
99.72%
Color and Shape:
Solid
Molecular weight:
561.46
Ref: TM-TQ0015
| 1mg | 80.00 € | ||
| 2mg | 103.00 € | ||
| 5mg | 172.00 € | ||
| 10mg | 299.00 € | ||
| 25mg | 510.00 € | ||
| 50mg | 732.00 € | ||
| 100mg | 1,003.00 € | ||
| 1mL*10mM (DMSO) | 211.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Linifanib
CAS:796967-16-3
Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), …
Formula:
C21H18FN5O
Purity:
98% - 98.24%
Color and Shape:
Solid
Molecular weight:
375.4
Ref: TM-T2514
| 5mg | 51.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 268.00 € | ||
| 200mg | 493.00 € | ||
| 500mg | 802.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GW2580
CAS:870483-87-7
GW2580 (SC-203877) is a specific, oral-bioavailable CSF-1R inhibitor for c-FMS.
Formula:
C20H22N4O3
Purity:
100% - 99.86%
Color and Shape:
Solid
Molecular weight:
366.41
Ref: TM-T2659
| 5mg | 50.00 € | ||
| 10mg | 68.00 € | ||
| 50mg | 86.00 € | ||
| 100mg | 95.00 € | ||
| 200mg | 135.00 € | ||
| 500mg | 266.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Vimseltinib
CAS:1628606-05-2
Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 …
Formula:
C23H25N7O2
Purity:
98.98% - 99.57%
Color and Shape:
Solid
Molecular weight:
431.49
Ref: TM-T10652
| 1mg | 91.00 € | ||
| 5mg | 186.00 € | ||
| 10mg | 308.00 € | ||
| 25mg | 527.00 € | ||
| 50mg | 719.00 € | ||
| 100mg | 926.00 € | ||
| 1mL*10mM (DMSO) | 212.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Dovitinib
CAS:405169-16-6
Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Formula:
C21H21FN6O
Purity:
98% - 99.78%
Color and Shape:
Solid
Molecular weight:
392.43
Ref: TM-T6289
| 5mg | 46.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 199.00 € | ||
| 100mg | 321.00 € | ||
| 200mg | 479.00 € | ||
| 500mg | 766.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PLX5622
CAS:1303420-67-8
PLX5622 is a selective, orally active and blood-brain barrier permeable CSF1R inhibitor. PLX5622 induces elimination …
Formula:
C21H19F2N5O
Purity:
98% - 99.89%
Color and Shape:
Solid
Molecular weight:
395.41
Ref: TM-T7100
| 5mg | 94.00 € | ||
| 10mg | 155.00 € | ||
| 25mg | 302.00 € | ||
| 50mg | 499.00 € | ||
| 100mg | 604.00 € | ||
| 500mg | 1,283.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AZD7507
CAS:1041852-85-0
AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.
Formula:
C23H27FN6O3
Purity:
98.01% - 99.09%
Color and Shape:
Solid
Molecular weight:
454.5
Ref: TM-T14380
| 1mg | 51.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 164.00 € | ||
| 25mg | 295.00 € | ||
| 50mg | 426.00 € | ||
| 100mg | 593.00 € | ||
| 200mg | 801.00 € | ||
| 1mL*10mM (DMSO) | 129.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Nampt-IN-1
CAS:1698878-14-6
Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with …
Formula:
C20H25N3O5S
Purity:
96.82% - 99.4%
Color and Shape:
Solid
Molecular weight:
419.49
Ref: TM-T4376
| 1mg | 39.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 134.00 € | ||
| 25mg | 253.00 € | ||
| 50mg | 423.00 € | ||
| 100mg | 625.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
c-Fms-IN-3
CAS:885704-21-2
c-Fms-IN-3 is a novel inhibitor of the c-FMS and can be used in studies about …
Formula:
C23H30N6O
Purity:
99.92%
Color and Shape:
Solid
Molecular weight:
406.52
Ref: TM-T10649
| 1mg | 50.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 273.00 € | ||
| 50mg | 370.00 € | ||
| 100mg | 541.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
