c-Fms
c-Fms inhibitors target the Colony Stimulating Factor-1 Receptor (c-Fms), a tyrosine kinase involved in the regulation of macrophages and other immune cells. c-Fms signaling plays a role in the proliferation, differentiation, and survival of these cells. Dysregulation of c-Fms is associated with diseases such as cancer, inflammatory conditions, and osteoporosis. At CymitQuimica, we offer c-Fms inhibitors to support your research in immunology, oncology, and inflammatory diseases.
Found 100 products of "c-Fms"
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CSF1R-IN-1
CAS:CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.Formula:C25H20F3N5O2Purity:97.02% - 98.56%Color and Shape:SolidMolecular weight:479.45Ref: TM-T10894
1mg88.00€5mg200.00€10mg309.00€25mg522.00€50mg747.00€100mg1,035.00€200mg1,378.00€1mL*10mM (DMSO)219.00€Emactuzumab
CAS:Emactuzumab(RG 7155) is a monoclonal antibody against colony-stimulating factor-1 receptor targeting tumor-associated macrophages (TAMs) Emactuzumab has
Purity:SDS-PAGE:98.3%;SEC-HPLC:97.3%Color and Shape:LiquidMolecular weight:144.4 kDaCSF1R-IN-2
CAS:CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).Formula:C20H20FN7O2Purity:99.29%Color and Shape:SolidMolecular weight:409.42Mavrilimumab
CAS:Mavrilimumab (CAM 3001), a monoclonal antibody, blocks GM-CSF signaling, potentially reducing inflammation in rheumatoid arthritis.
Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:143.2 kDaEdicotinib
CAS:Edicotinib (JNJ-527) is a blood-brain permeable, selective CSF-1R inhibitor, with lesser inhibitory effects on KIT and FLT3.Cost-effective and quality-assured.
Formula:C27H35N5O2Purity:98.58% - 99.72%Color and Shape:SolidMolecular weight:461.6PLX647 dihydrochloride
CAS:PLX647 dihydrochloride: potent FMS/KIT inhibitor (IC50: 28/16 nM), highly selective, limited FLT3/KDR activity, oral use.Formula:C21H19Cl2F3N4Color and Shape:SolidMolecular weight:455.31Adrixetinib TFA
Adrixetinib (TFA) is a protein tyrosine kinase inhibitor that possesses antineoplastic properties [1] [2] [3].Color and Shape:Odour SolidOtilimab
CAS:Otilimab, a humanized monoclonal antibody, blocks GM-CSF to reduce inflammation and may treat severe COVID-19 pneumonia.
Purity:> 95%Color and Shape:LiquidMolecular weight:142.22 kDaGENZ-882706(Raceme)
CAS:GENZ-882706(Raceme) is the racemate of GENZ-882706.Formula:C26H25N5O3Purity:98%Color and Shape:SolidMolecular weight:455.51Pyrithyldione
CAS:Pyrithyldione is a sedative-hypnotic agent known to potentially induce agranulocytosis.Formula:C9H13NO2Color and Shape:SolidMolecular weight:167.21PXB17
PXB17 inhibits CSF1R activation (IC50= 1.7 nM) by blocking the PI3K/AKT/mTORC1 signaling pathway. It is effective orally, significantly suppresses the growth of colorectal cancer (CRC), enhances the efficacy of PD-1 monoclonal antibodies (PD-1mAb), and reduces the recurrence of CRC tumors.Formula:C29H35N7O4Molecular weight:545.27505cFMS Receptor Inhibitor IV
CAS:cFMS Receptor Inhibitor IV is an inhibitor of c-Fms tyrosine kinase.
Formula:C22H26N4O2Purity:99.70%Color and Shape:SolidMolecular weight:378.47M4205
CAS:M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.Formula:C29H32N8OPurity:99.07%Color and Shape:SolidMolecular weight:508.62Ref: TM-T9689
1mg50.00€5mg110.00€10mg170.00€25mg290.00€50mg414.00€100mg572.00€200mg772.00€1mL*10mM (DMSO)122.00€Antifibrotic agent 1
Antifibrotic agent 1 is an orally active medication designed to treat idiopathic pulmonary fibrosis (IPF). It effectively mitigates IPF-related processes, including TGF-β-induced epithelial-mesenchymal transition (EMT) and fibroblast-to-myofibroblast transition (FMT), as well as profibrotic M2 polarization. Antifibrotic agent 1 selectively inhibits CSF-1R, PDGFR-α, and Src family kinases (SFKs), while sparing VEGFR, FGFR, and Abl to minimize off-target toxicity. In a bleomycin (BLM)-induced pulmonary fibrosis mouse model, it demonstrates strong antifibrotic activity.Formula:C27H23ClN6O2Color and Shape:SolidMolecular weight:498.1571Sotuletinib hydrochloride
CAS:Sotuletinib hydrochloride (BLZ945 HCl) is a selective, brain-penetrant CSF-1R (c-Fms) inhibitor (IC50=1 nM),for ALS and TNBC.Formula:C20H23ClN4O3SPurity:98.812%Color and Shape:SolidMolecular weight:434.94CSF1R-IN-17
CSF1R-IN-17 (compound 9) is a potent, selective antagonist of CSF1R, exhibiting an inhibition concentration half-maximum (IC50) of 0.2 nM.Formula:C20H25N5O2Purity:98%Color and Shape:SolidMolecular weight:367.44Anti-CSF1R Antibody (2I506)
Anti-CSF1R Antibody (2I506) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (2I506) can be used in ELISA.Color and Shape:Odour LiquidAnti-CSF1R Antibody (7V18)
Anti-CSF1R Antibody (7V18) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (7V18) can be used in ELISA.Color and Shape:Odour LiquidAnti-CSF1R Antibody (8O797)
Anti-CSF1R Antibody (8O797) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (8O797) can be used in ELISA.Color and Shape:Odour LiquidAnti-CSF1R Antibody (4Y587)
Anti-CSF1R Antibody (4Y587) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (4Y587) can be used in FCM.Color and Shape:Odour Liquid
