c-Kit
c-Kit inhibitors are compounds that block the activity of the Stem Cell Factor Receptor (c-Kit), a tyrosine kinase that plays a pivotal role in cell survival, proliferation, and differentiation, particularly in hematopoietic cells. Mutations in c-Kit are linked to various cancers, including gastrointestinal stromal tumors (GIST) and leukemia. At CymitQuimica, we provide c-Kit inhibitors to support your research in oncology, hematology, and stem cell biology.
Found 117 products for "c-Kit".
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Anti-C-Kit Antibody-APC (8E724)
Anti-C-Kit Antibody-APC (8E724) is a APC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-APC (8E724) can be used in FCM.Color and Shape:Odour LiquidAnti-C-Kit Antibody (2T761)
Anti-C-Kit Antibody (2T761) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (2T761) can be used in ELISA(Det).Color and Shape:Odour LiquidAST 487
CAS:AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.Formula:C26H30F3N7O2Purity:98.17% - 99.56%Color and Shape:SolidMolecular weight:529.56Ref: TM-T4053
1mg34.00€2mg49.00€5mg74.00€1mL*10mM (DMSO)87.00€10mg113.00€25mg177.00€50mg334.00€100mg500.00€500mg1,099.00€ISCK03
CAS:ISCK03 is a selective SCF/c-Kit inhibitor.Formula:C19H21N3O2SPurity:98.39%Color and Shape:White SolidMolecular weight:355.45JNJ-38158471
CAS:JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Formula:C15H17ClN6O3Purity:97.08%Color and Shape:White SolidMolecular weight:364.79Ref: TM-T22349
1mg38.00€5mg78.00€1mL*10mM (DMSO)84.00€10mg103.00€25mg172.00€50mg250.00€100mg338.00€200mg464.00€OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formula:C22H16F3N3O2SPurity:99.67%Color and Shape:White SolidMolecular weight:443.44Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formula:C28H30N6OSPurity:97.56% - >99.99%Color and Shape:White SolidMolecular weight:498.64Toceranib Phosphate
CAS:Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.Formula:C22H28FN4O6PPurity:98.56%Color and Shape:SolidMolecular weight:494.45BLU-263
CAS:BLU-263 is an investigational, potent, and selective oral small molecule inhibitor of KIT with sub-nanomolar potency against D816V-mutant KIT.Formula:C27H29FN10OPurity:99.01% - 99.67%Color and Shape:White SolidMolecular weight:528.58Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formula:C24H21BrFN5O2Purity:99.07% - 99.62%Color and Shape:White SolidMolecular weight:510.36Ref: TM-T8482
1mg71.00€2mg92.00€5mg157.00€1mL*10mM (DMSO)170.00€10mg260.00€25mg409.00€50mg615.00€100mg862.00€SU14813
CAS:SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Formula:C23H27FN4O4Purity:98.13%Color and Shape:Yellow SolidMolecular weight:442.48Avapritinib
CAS:Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.Formula:C26H27FN10Purity:96.59% - 99.70%Color and Shape:SolidMolecular weight:498.56Ref: TM-T5109
1mg35.00€5mg75.00€1mL*10mM (DMSO)84.00€10mg114.00€25mg222.00€50mg334.00€100mg557.00€200mg790.00€Multi-kinase inhibitor 1
CAS:Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Formula:C20H17F3N4O3Purity:99.87%Color and Shape:SolidMolecular weight:418.37Ref: TM-T4191
1mg37.00€2mg52.00€5mg79.00€1mL*10mM (DMSO)87.00€10mg101.00€25mg177.00€50mg268.00€100mg385.00€Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formula:C24H24N4O5SPurity:98.97% - 99.88%Color and Shape:SolidMolecular weight:480.54Ref: TM-T4315
1mg44.00€5mg90.00€1mL*10mM (DMSO)90.00€10mg145.00€25mg268.00€50mg439.00€100mg700.00€200mg954.00€Flumatinib
CAS:Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.Formula:C29H29F3N8OPurity:99.39% - 99.95%Color and Shape:White SolidMolecular weight:562.59Ref: TM-T4320
1mg34.00€5mg63.00€10mg82.00€1mL*10mM (DMSO)82.00€25mg120.00€50mg155.00€100mg259.00€200mg388.00€500mg642.00€AZD2932
CAS:AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.Formula:C24H25N5O4Purity:98.37% - 98.60%Color and Shape:SolidMolecular weight:447.49AZD3229 Tosylate
CAS:AZD3229 Tosylate is a highly potent inhibitor targeting mutant forms of the pan-KIT enzyme, with a primary application in the treatment of gastrointestinalFormula:C31H34FN7O6SColor and Shape:SolidMolecular weight:651.71Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formula:C35H30N4O4Purity:97.61% - >99.99%Color and Shape:SolidMolecular weight:570.64Ref: TM-T3211
1mg49.00€5mg84.00€1mL*10mM (DMSO)90.00€10mg119.00€25mg205.00€50mg310.00€100mg462.00€500mg1,035.00€Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Formula:C24H27FN6O4Purity:99.54% - 99.77%Color and Shape:SolidMolecular weight:482.51Tandutinib
CAS:Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3Formula:C31H42N6O4Purity:99.45% - ≥98%Color and Shape:SolidMolecular weight:562.7
