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c-Kit

c-Kit

c-Kit inhibitors are compounds that block the activity of the Stem Cell Factor Receptor (c-Kit), a tyrosine kinase that plays a pivotal role in cell survival, proliferation, and differentiation, particularly in hematopoietic cells. Mutations in c-Kit are linked to various cancers, including gastrointestinal stromal tumors (GIST) and leukemia. At CymitQuimica, we provide c-Kit inhibitors to support your research in oncology, hematology, and stem cell biology.

Found 101 products of "c-Kit"

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  • ISCK03
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    ISCK03

    CAS:
    <p>ISCK03 is a selective SCF/c-Kit inhibitor.</p>
    Formula:C19H21N3O2S
    Purity:98.39%
    Color and Shape:Solid
    Molecular weight:355.45

    Ref: TM-T3452

  • JNJ-38158471
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    JNJ-38158471

    CAS:
    <p>JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .</p>
    Formula:C15H17ClN6O3
    Purity:97.08%
    Color and Shape:Solid
    Molecular weight:364.79

    Ref: TM-T22349

  • OSI-930
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    OSI-930

    CAS:
    <p>OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.</p>
    Formula:C22H16F3N3O2S
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:443.44

    Ref: TM-T2624

  • Masitinib
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    Masitinib

    CAS:
    <p>Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.</p>
    Formula:C28H30N6OS
    Purity:97.56% - >99.99%
    Color and Shape:Solid
    Molecular weight:498.64

    Ref: TM-T2609

  • Toceranib Phosphate
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    Toceranib Phosphate

    CAS:
    <p>Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.</p>
    Formula:C22H28FN4O6P
    Purity:98.56%
    Color and Shape:Solid
    Molecular weight:494.45

    Ref: TM-T7394

  • BLU-263
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    BLU-263

    CAS:
    <p>BLU-263 is an investigational, potent, and selective oral small molecule inhibitor of KIT with sub-nanomolar potency against D816V-mutant KIT.</p>
    Formula:C27H29FN10O
    Purity:99.01% - 99.67%
    Color and Shape:Solid
    Molecular weight:528.58

    Ref: TM-T9295

  • Ripretinib
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    Ripretinib

    CAS:
    <p>Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.</p>
    Formula:C24H21BrFN5O2
    Purity:99.07% - 99.38%
    Color and Shape:Solid
    Molecular weight:510.36

    Ref: TM-T8482

  • SU14813
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    SU14813

    CAS:
    <p>SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.</p>
    Formula:C23H27FN4O4
    Purity:98.13%
    Color and Shape:Solid
    Molecular weight:442.48

    Ref: TM-T7945

  • Avapritinib
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    Avapritinib

    CAS:
    <p>Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.</p>
    Formula:C26H27FN10
    Purity:96.59% - 99.7%
    Color and Shape:Solid
    Molecular weight:498.56

    Ref: TM-T5109

  • Multi-kinase inhibitor 1
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    Multi-kinase inhibitor 1

    CAS:
    <p>Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.</p>
    Formula:C20H17F3N4O3
    Purity:99.34%
    Color and Shape:Solid
    Molecular weight:418.37

    Ref: TM-T4191

  • Ki20227
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    Ki20227

    CAS:
    <p>Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).</p>
    Formula:C24H24N4O5S
    Purity:98.97% - 99.88%
    Color and Shape:Solid
    Molecular weight:480.54

    Ref: TM-T4315

  • Flumatinib
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    Flumatinib

    CAS:
    <p>Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.</p>
    Formula:C29H29F3N8O
    Purity:99.39% - 99.95%
    Color and Shape:Solid
    Molecular weight:562.59

    Ref: TM-T4320

  • AZD2932
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    AZD2932

    CAS:
    <p>AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.</p>
    Formula:C24H25N5O4
    Purity:97.71% - 98.37%
    Color and Shape:Solid
    Molecular weight:447.49

    Ref: TM-T1836

  • AZD3229 Tosylate
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    AZD3229 Tosylate

    CAS:
    <p>AZD3229 Tosylate is a highly potent inhibitor targeting mutant forms of the pan-KIT enzyme, with a primary application in the treatment of gastrointestinal</p>
    Formula:C31H34FN7O6S
    Color and Shape:Solid
    Molecular weight:651.71

    Ref: TM-T71894

  • Midostaurin
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    Midostaurin

    CAS:
    <p>PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.</p>
    Formula:C35H30N4O4
    Purity:97.61% - >99.99%
    Color and Shape:Solid
    Molecular weight:570.64

    Ref: TM-T3211

  • Dovitinib lactate
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    Dovitinib lactate

    CAS:
    <p>Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).</p>
    Formula:C24H27FN6O4
    Purity:99.54% - 99.77%
    Color and Shape:Solid
    Molecular weight:482.51

    Ref: TM-T7104

  • Tandutinib
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    Tandutinib

    CAS:
    <p>Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3</p>
    Formula:C31H42N6O4
    Purity:99.45% - ≥98%
    Color and Shape:White Solid
    Molecular weight:562.7

    Ref: TM-T1667

  • Vimseltinib
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    Vimseltinib

    CAS:
    <p>Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: &lt;0.01 μM and 0.1-1 μM).</p>
    Formula:C23H25N7O2
    Purity:99.05% - 99.57%
    Color and Shape:Solid
    Molecular weight:431.49

    Ref: TM-T10652

  • SKLB4771
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    SKLB4771

    CAS:
    <p>SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.</p>
    Formula:C25H27N7O3S2
    Purity:98% - >99.99%
    Color and Shape:Solid
    Molecular weight:537.66

    Ref: TM-T2051

  • AZD3229
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    AZD3229

    CAS:
    <p>AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors.</p>
    Formula:C24H26FN7O3
    Purity:98.83%
    Color and Shape:Solid
    Molecular weight:479.51

    Ref: TM-T5409