CymitQuimica logo
c-Kit

c-Kit

c-Kit inhibitors are compounds that block the activity of the Stem Cell Factor Receptor (c-Kit), a tyrosine kinase that plays a pivotal role in cell survival, proliferation, and differentiation, particularly in hematopoietic cells. Mutations in c-Kit are linked to various cancers, including gastrointestinal stromal tumors (GIST) and leukemia. At CymitQuimica, we provide c-Kit inhibitors to support your research in oncology, hematology, and stem cell biology.

Found 101 products of "c-Kit"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • c-Kit-IN-1
    Targetmol
    + Info

    c-Kit-IN-1

    CAS:
    <p>c-Kit-IN-1 (DCC-2618) is an effective inhibitor of c-Met and c-Kit (IC50s&lt;200 nM).</p>
    Formula:C26H21F2N5O3
    Purity:98.72% - 98.73%
    Color and Shape:Solid
    Molecular weight:489.47

    Ref: TM-T4332

  • Imatinib
    Targetmol
    + Info

    Imatinib

    CAS:
    <p>Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kit</p>
    Formula:C29H31N7O
    Purity:99.42% - 99.94%
    Color and Shape:Off White Powder
    Molecular weight:493.6

    Ref: TM-T6230

  • Telatinib
    Targetmol
    + Info

    Telatinib

    CAS:
    <p>Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.</p>
    Formula:C20H16ClN5O3
    Purity:97.61% - 99.81%
    Color and Shape:Solid
    Molecular weight:409.83

    Ref: TM-T6166

  • Linifanib
    Targetmol
    + Info

    Linifanib

    CAS:
    <p>Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and</p>
    Formula:C21H18FN5O
    Purity:98% - 98.24%
    Color and Shape:Solid
    Molecular weight:375.4

    Ref: TM-T2514

  • GW786034B
    Targetmol
    + Info

    GW786034B

    CAS:
    <p>Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.</p>
    Formula:C21H23N7O2S·HCl
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:473.98

    Ref: TM-T6930

  • N-Desethylsunitinib hydrochloride
    Targetmol
    + Info

    N-Desethylsunitinib hydrochloride

    CAS:
    <p>N-Desethylsunitinib HCl, active sunitinib metabolite, inhibits VEGFR, PDGFRβ, KIT.</p>
    Formula:C20H24ClFN4O2
    Purity:99.42%
    Color and Shape:Solid
    Molecular weight:406.88

    Ref: TM-T12145L

  • Motesanib
    Targetmol
    + Info

    Motesanib

    CAS:
    <p>Motesanib (AMG 706) orally blocks VEGFR, PDGFR, Kit, Ret; curbing angiogenesis and cancer cell growth.</p>
    Formula:C22H23N5O
    Purity:98% - 99.09%
    Color and Shape:Solid
    Molecular weight:373.45

    Ref: TM-T2288

  • Regorafenib
    Targetmol
    + Info

    Regorafenib

    CAS:
    <p>Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally</p>
    Formula:C21H15ClF4N4O3
    Purity:98% - 99.95%
    Color and Shape:Solid
    Molecular weight:482.82

    Ref: TM-T1792

  • Lenvatinib mesylate
    Targetmol
    + Info

    Lenvatinib mesylate

    CAS:
    <p>Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.</p>
    Formula:C22H23ClN4O7S
    Purity:99.03% - 99.79%
    Color and Shape:Solid
    Molecular weight:522.96

    Ref: TM-T8541

  • Tyrphostin AG1296
    Targetmol
    + Info

    Tyrphostin AG1296

    CAS:
    <p>Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.</p>
    Formula:C16H14N2O2
    Purity:99.94% - >99.99%
    Color and Shape:Solid
    Molecular weight:266.29

    Ref: TM-T6711

  • Dovitinib lactate hydrate
    Targetmol
    + Info

    Dovitinib lactate hydrate

    CAS:
    <p>Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).</p>
    Formula:C24H27FN6O4
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:482.51

    Ref: TM-T6479

  • Amuvatinib
    Targetmol
    + Info

    Amuvatinib

    CAS:
    <p>Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.</p>
    Formula:C23H21N5O3S
    Purity:99.38% - >99.99%
    Color and Shape:Solid
    Molecular weight:447.51

    Ref: TM-T2516

  • Pexidartinib
    Targetmol
    + Info

    Pexidartinib

    CAS:
    <p>Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential</p>
    Formula:C20H15ClF3N5
    Purity:98.34% - 99.45%
    Color and Shape:Solid
    Molecular weight:417.81

    Ref: TM-T2115

  • Cabozantinib
    Targetmol
    + Info

    Cabozantinib

    CAS:
    <p>Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).</p>
    Formula:C28H24FN3O5
    Purity:99.68% - 99.88%
    Color and Shape:Solid
    Molecular weight:501.51

    Ref: TM-T2586

  • Flumatinib mesylate
    Targetmol
    + Info

    Flumatinib mesylate

    CAS:
    <p>Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.</p>
    Formula:C30H33F3N8O4S
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:658.69

    Ref: TM-T7861

  • Cabozantinib hydrochloride
    Targetmol
    + Info

    Cabozantinib hydrochloride

    CAS:
    <p>Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6</p>
    Formula:C28H25ClFN3O5
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:537.96

    Ref: TM-T5164

  • Dovitinib
    Targetmol
    + Info

    Dovitinib

    CAS:
    <p>Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.</p>
    Formula:C21H21FN6O
    Purity:99.35% - 99.92%
    Color and Shape:Solid
    Molecular weight:392.43

    Ref: TM-T6289

  • Sitravatinib
    Targetmol
    + Info

    Sitravatinib

    CAS:
    <p>Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and</p>
    Formula:C33H29F2N5O4S
    Purity:98.9% - 99.85%
    Color and Shape:Solid
    Molecular weight:629.68

    Ref: TM-T4349

  • Masitinib mesylate
    Targetmol
    + Info

    Masitinib mesylate

    CAS:
    <p>Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;</p>
    Formula:C29H34N6O4S2
    Purity:97.67% - 98.44%
    Color and Shape:Solid
    Molecular weight:594.75

    Ref: TM-T8544

  • Toceranib
    Targetmol
    + Info

    Toceranib

    CAS:
    <p>Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.</p>
    Formula:C22H25FN4O2
    Purity:97.14%
    Color and Shape:Solid
    Molecular weight:396.46

    Ref: TM-T13178