Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1504 products of "Autophagy"
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Autophinib
CAS:Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay andFormula:C14H11ClN6O3Purity:99.25% - 99.41%Color and Shape:SolidMolecular weight:346.73Ref: TM-T4219
2mg39.00€5mg58.00€10mg88.00€25mg160.00€50mg215.00€100mg334.00€200mg494.00€1mL*10mM (DMSO)66.00€Vps34-IN-1
CAS:Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.Formula:C21H24ClN7OPurity:97.04%Color and Shape:SolidMolecular weight:425.91Ref: TM-T7015
1mg43.00€2mg56.00€5mg88.00€10mg124.00€25mg207.00€50mg333.00€100mg477.00€1mL*10mM (DMSO)96.00€Peretinoin
CAS:Peretinoin (NIK333) is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as RXR and RAR.Formula:C20H30O2Purity:97.23%Color and Shape:SolidMolecular weight:302.45Ref: TM-TQ0064
1mg38.00€2mg49.00€5mg84.00€10mg119.00€25mg219.00€50mg380.00€100mg567.00€500mg1,215.00€1mL*10mM (DMSO)93.00€U0126-EtOH
CAS:U0126-etoh (U0126 Ethanol) is a non-ATP competitive inhibitor of MEK1 (IC50=72 nM) and MEK2 (IC50=58 nM) with selectivity, inhibit autophagy. Low-Cost!Formula:C18H16N6S2·C2H6OPurity:99.72% - 99.88%Color and Shape:SolidMolecular weight:426.6Tenovin-6
CAS:Tenovin-6 is a p53 transcriptional activity agonist.Formula:C25H34N4O2SPurity:98.89% - >99.99%Color and Shape:SolidMolecular weight:454.63Ref: TM-T1818
1mg40.00€2mg52.00€5mg73.00€10mg93.00€25mg148.00€50mg219.00€100mg371.00€500mg882.00€1mL*10mM (DMSO)74.00€Ligustilide
CAS:3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.Formula:C12H14O2Purity:96.03% - 99.97%Color and Shape:Yellow Brown PowderMolecular weight:190.24AZD1208
CAS:AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.
Formula:C21H21N3O2SPurity:97.24% - 99.83%Color and Shape:SolidMolecular weight:379.48Berbamine dihydrochloride
CAS:Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.Formula:C37H42Cl2N2O6Purity:95% - 99.99%Color and Shape:SolidMolecular weight:681.65Pinosylvin
CAS:Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.Formula:C14H12O2Purity:99.89% - 99.91%Color and Shape:SolidMolecular weight:212.24Entinostat
CAS:Entinostat (MS-275) is an HDAC class I with oral activity. Entinostat has antitumor activity. Cost-effective and quality-assured.Formula:C21H20N4O3Purity:98% - 99.74%Color and Shape:SolidMolecular weight:376.41Isosorbide Mononitrate
CAS:Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.Formula:C6H9NO6Purity:98.16%Color and Shape:Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionMolecular weight:191.14Juglanin
CAS:Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.Formula:C20H18O10Purity:98.8% - 99.33%Color and Shape:SolidMolecular weight:418.35CCT128930 hydrochloride
CAS:CCT128930 hydrochloride: Potent AKT inhibitor (IC50=6 nM), 28x selective over PKA, 20x over p70S6K, induces cell cycle arrest & DNA damage.Formula:C18H21Cl2N5Purity:98.55%Color and Shape:SolidMolecular weight:378.3Ref: TM-T6303L
1mg49.00€5mg92.00€10mg148.00€25mg240.00€50mg359.00€100mg523.00€200mg772.00€1mL*10mM (DMSO)104.00€Gartanin
CAS:Gartanin enhances androgen receptor degradation and has neuroprotective effects by boosting HO-1, AMPK, SIRT1, and PGC-1α pathways.Formula:C23H24O6Purity:99.64% - 99.85%Color and Shape:SolidMolecular weight:396.43Ref: TM-TN1677
1mg96.00€5mg268.00€10mg409.00€25mg660.00€50mg888.00€100mg1,224.00€1mL*10mM (DMSO)281.00€Autogramin-1
CAS:Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.Formula:C23H27N5O5SPurity:97.69% - 99.25%Color and Shape:SolidMolecular weight:485.56PTC-209 hydrobromide
CAS:PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in
Formula:C17H13Br2N5OS·HBrPurity:99.91%Color and Shape:SolidMolecular weight:576.1Ref: TM-T6178
1mg37.00€5mg78.00€10mg124.00€25mg265.00€50mg465.00€100mg753.00€200mg1,035.00€1mL*10mM (DMSO)89.00€NSC 185058
CAS:NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.Formula:C11H9N3SPurity:99.27%Color and Shape:SolidMolecular weight:215.27XL388
CAS:XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.Formula:C23H22FN3O4SPurity:99.39% - 99.53%Color and Shape:SolidMolecular weight:455.5Autocamtide-2-related inhibitory peptide
CAS:Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.Formula:C64H116N22O19Purity:>99.99%Color and Shape:SolidMolecular weight:1497.74PF-543 hydrochloride
CAS:PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2Formula:C27H32ClNO4SPurity:98.9% - 99.93%Color and Shape:SolidMolecular weight:502.1
