Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1486 products of "Autophagy"
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KAN0438757
CAS:<p>KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.</p>Formula:C21H18FNO7SPurity:99.34%Color and Shape:SolidMolecular weight:447.43Pravastatin sodium
CAS:Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.Formula:C23H35NaO7Purity:97.14% - 99.97%Color and Shape:White Crystalline PowderMolecular weight:446.52Raloxifene hydrochloride
CAS:Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.Formula:C28H28ClNO4SPurity:98% - 99.97%Color and Shape:Light Yellow SolidMolecular weight:510.044Isotretinoin
CAS:Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promoteFormula:C20H28O2Purity:97.01% - 98.06%Color and Shape:Reddish-Orange Plates From Isopropyl Alcohol (Ntp 1992)Molecular weight:300.44Sorafenib
CAS:Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57Formula:C21H16ClF3N4O3Purity:98% - 99.89%Color and Shape:SolidMolecular weight:464.82Ivermectin
CAS:Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.Formula:C48H74O14Purity:94.11% - 99.71%Color and Shape:SolidMolecular weight:875.09Naringin
CAS:Naringin: flavanone glycoside with blood lipid-reducing, antioxidant, anticancer properties, inhibits cytochrome P450.Formula:C27H32O14Purity:99.23%Color and Shape:Beige Creamish Powder Solid Solid Particulate/PowderMolecular weight:580.53Gefitinib
CAS:Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations.Formula:C22H24ClFN4O3Purity:99.92% - >99.99%Color and Shape:Light-Yellow Crystalline PowderMolecular weight:446.9Aumitin
CAS:Aumitin inhibits autophagy (IC50: 0.12-0.24μM), targets complex I, and blocks mitochondrial respiration.Formula:C24H20ClN5OPurity:99.13%Color and Shape:SolidMolecular weight:429.9Deferoxamine Mesylate
CAS:Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.Formula:C26H52N6O11SPurity:94.68% - 99.8%Color and Shape:SolidMolecular weight:656.79Theophylline
CAS:Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and centralFormula:C7H8N4O2Purity:99.65% - 99.98%Color and Shape:White Solid PowderMolecular weight:180.16Letrozole
CAS:<p>Letrozole (CGS 20267) is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor.</p>Formula:C17H11N5Purity:98.67% - 99.84%Color and Shape:White To Off-Whitecrystalline PowderMolecular weight:285.3Isoliquiritigenin
CAS:Isoliquiritigenin (ISL) is a natural flavonoid that inhibits influenza virus and aldose reductase. Isoliquiritigenin has antitumor effect. Cost-effective and quality-assured.Formula:C15H12O4Purity:97.61% - 99.44%Color and Shape:PowderMolecular weight:256.25Nitrendipine
CAS:<p>Nitrendipine is a vasodilating calcium channel blocker and antihypertensive that preserves kidney function and promotes sodium excretion.</p>Formula:C18H20N2O6Purity:99% - 99.55%Color and Shape:SolidMolecular weight:360.36Erlotinib
CAS:Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Formula:C22H23N3O4Purity:98.19% - 99.98%Color and Shape:White To Off-White PowderMolecular weight:393.44Oxidopamine hydrochloride
CAS:Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.Formula:C8H12ClNO3Purity:98.34% - 99.85%Color and Shape:Physical Description Beige Solid (Ntp 1992)Molecular weight:205.64Rhein
CAS:Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.Formula:C15H8O6Purity:99.04%Color and Shape:Physical Description Yellow Needles (From Methanol) Or Yellow-Brown Powder (Ntp 1992)Molecular weight:284.22Bergenin
CAS:Bergenin (Bengenin) is a polyphenol, which is an effective antinarcotic agent with antioxidant action.Formula:C14H16O9Purity:99.55% - 99.60%Color and Shape:The Loose White Needle Crystal Powder Or CrystallineMolecular weight:328.27Carvedilol phosphate hemihydrate
CAS:Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent.Formula:C24H26N2O4·5H2O·H3O4PPurity:99.24% - 99.98%Color and Shape:SolidMolecular weight:513.49Nortriptyline hydrochloride
CAS:Nortriptyline HCl, a metabolite of amitriptyline, treats major and atypical depression, dysthymia.Formula:C19H22ClNPurity:99.85% - ≥95%Color and Shape:SolidMolecular weight:299.84
