Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
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Degrasyn
CAS:856243-80-6
Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S …
Formula:
C19H18BrN3O
Purity:
98.32% - 99.98%
Color and Shape:
Solid
Molecular weight:
384.27
Ref: TM-T6300
| 5mg | 63.00 € | ||
| 10mg | 100.00 € | ||
| 25mg | 195.00 € | ||
| 50mg | 352.00 € | ||
| 100mg | 522.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Nesolicaftor
CAS:1953130-87-4
Nesolicaftor (PTI-428) specifically enhances cystic fibrosis transmembrane conductance regulator protein synthesis.
Formula:
C18H18N4O4
Purity:
98.64%
Color and Shape:
Solid
Molecular weight:
354.36
Ref: TM-T16681
| 1mg | 97.00 € | ||
| 5mg | 217.00 € | ||
| 10mg | 381.00 € | ||
| 25mg | 657.00 € | ||
| 50mg | 936.00 € | ||
| 100mg | 1,266.00 € | ||
| 1mL*10mM (DMSO) | 239.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Norepinephrine
CAS:51-41-2
Norepinephrine (Levophed) can stimulate apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic …
Formula:
C8H11NO3
Purity:
98.56% - 99.84%
Color and Shape:
Colorless Micr°Crystals Solid
Molecular weight:
169.18
Ref: TM-T7044
| 5mg | 30.00 € | ||
| 100mg | 48.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Purvalanol A
CAS:212844-53-6
Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM …
Formula:
C19H25ClN6O
Purity:
98.13% - 98.91%
Color and Shape:
Powder
Molecular weight:
388.89
Ref: TM-T2059
| 5mg | 39.00 € | ||
| 10mg | 49.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 122.00 € | ||
| 100mg | 193.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Hydroxychloroquine
CAS:118-42-3
HCQ, an anti-malarial, may induce cancer cell death and is being explored for COVID-19.
Formula:
C18H26ClN3O
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
335.87
Ref: TM-T9287
| 50mg | 36.00 € | ||
| 100mg | 46.00 € | ||
| 200mg | 60.00 € | ||
| 500mg | 88.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Talarozole
CAS:201410-53-9
Talarozole is an oral RAMBA for treating acne and psoriasis, inhibiting CYP26A1/26B1 with IC50s of …
Formula:
C21H23N5S
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
377.51
Ref: TM-T7370
| 1mg | 71.00 € | ||
| 5mg | 132.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 231.00 € | ||
| 50mg | 299.00 € | ||
| 100mg | 453.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
PD146176
CAS:4079-26-9
PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with …
Formula:
C15H11NS
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
237.32
Ref: TM-T7530
| 5mg | 48.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 144.00 € | ||
| 50mg | 257.00 € | ||
| 100mg | 448.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Nordihydroguaiaretic acid
CAS:500-38-9
Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective …
Formula:
C18H22O4
Purity:
97.82% - 99.91%
Color and Shape:
Solid
Molecular weight:
302.36
Ref: TM-TJS2190
| 25mg | 29.00 € | ||
| 50mg | 39.00 € | ||
| 100mg | 49.00 € | ||
| 500mg | 128.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Torin 2
CAS:1223001-51-1
Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for …
Formula:
C24H15F3N4O
Purity:
98.31% - 99.32%
Color and Shape:
Solid
Molecular weight:
432.4
Ref: TM-T6100
| 2mg | 41.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 252.00 € | ||
| 100mg | 375.00 € | ||
| 200mg | 557.00 € | ||
| 500mg | 885.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Regorafenib
CAS:755037-03-7
Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, …
Formula:
C21H15ClF4N4O3
Purity:
98% - 99.95%
Color and Shape:
Solid
Molecular weight:
482.82
Ref: TM-T1792
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 79.00 € | ||
| 50mg | 94.00 € | ||
| 100mg | 142.00 € | ||
| 200mg | 181.00 € | ||
| 500mg | 304.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
IITZ-01
CAS:1807988-47-1
IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for …
Formula:
C26H23FN8O
Purity:
99%
Color and Shape:
Solid
Molecular weight:
482.51
Ref: TM-T6799
| 5mg | 38.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 112.00 € | ||
| 50mg | 191.00 € | ||
| 100mg | 295.00 € | ||
| 200mg | 426.00 € | ||
| 1mL*10mM (DMSO) | 41.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Paeonol
CAS:552-41-0
Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with …
Formula:
C9H10O3
Purity:
100% - 98.55%
Color and Shape:
White To Beige Crystalline Powder
Molecular weight:
166.17
Ref: TM-T2900
| 1g | 69.00 € | ||
| 500mg | 50.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
CCG-1423
CAS:285986-88-1
CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.
Formula:
C18H13ClF6N2O3
Purity:
99.98%
Color and Shape:
Solid
Molecular weight:
454.75
Ref: TM-T2014
| 5mg | 38.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 159.00 € | ||
| 100mg | 256.00 € | ||
| 200mg | 399.00 € | ||
| 500mg | 646.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
A-867744
CAS:1000279-69-5
A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR …
Formula:
C20H19ClN2O3S
Purity:
95.66%
Color and Shape:
Solid
Molecular weight:
402.89
Ref: TM-TQ0117
| 2mg | 46.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 326.00 € | ||
| 100mg | 487.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Apigenin
CAS:520-36-5
Apigenin (NSC 83244) is an aromatic oil extracted from the flowers or leaves of the …
Formula:
C15H10O5
Purity:
97.95% - 99.66%
Color and Shape:
Yellow Needles From Aqueous Pyridine Solid
Molecular weight:
270.24
Ref: TM-T2175
| 1g | 294.00 € | ||
| 25mg | 49.00 € | ||
| 50mg | 59.00 € | ||
| 100mg | 96.00 € | ||
| 200mg | 125.00 € | ||
| 500mg | 198.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
ABT-751
CAS:141430-65-1
ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, …
Formula:
C18H17N3O4S
Purity:
98.84% - 99.48%
Color and Shape:
Solid
Molecular weight:
371.41
Ref: TM-T1758
| 5mg | 48.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 171.00 € | ||
| 100mg | 273.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Cordycepin
CAS:73-03-0
Cordycepin (3'-Deoxyadenosine) is a purine nucleoside antimetabolite and antibiotic isolated from the fungus Cordyceps militaris …
Formula:
C10H13N5O3
Purity:
100% - 99.78%
Color and Shape:
Crystalline Solid
Molecular weight:
251.24
Ref: TM-T2993
| 10mg | 55.00 € | ||
| 25mg | 100.00 € | ||
| 50mg | 169.00 € | ||
| 100mg | 263.00 € | ||
| 500mg | 629.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
TFEB activator 1
CAS:39777-61-2
TFEB activator 1 (Curcumin analog compound C1) is an activator of transcription factor EB (TFEB) …
Formula:
C19H18O3
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
294.34
Ref: TM-T8055
| 2mg | 41.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 91.00 € | ||
| 25mg | 161.00 € | ||
| 50mg | 270.00 € | ||
| 100mg | 418.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Corosolic acid
CAS:4547-24-4
Corosolic acid inhibits angiogenesis, suppresses FAK, fights various cancers, induces apoptosis, and degrades β-catenin.
Formula:
C30H48O4
Purity:
99.46% - 99.5%
Color and Shape:
Fine-Brown Yellow Powder
Molecular weight:
472.7
Ref: TM-T3391
| 5mg | 46.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 109.00 € | ||
| 50mg | 166.00 € | ||
| 100mg | 237.00 € | ||
| 200mg | 361.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
WYE-354
CAS:1062169-56-5
WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and …
Formula:
C24H29N7O5
Purity:
98.31% - 99.61%
Color and Shape:
Solid
Molecular weight:
495.53
Ref: TM-T6731
| 5mg | 50.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 152.00 € | ||
| 50mg | 275.00 € | ||
| 100mg | 356.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
