Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1477 products of "Autophagy"
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Dimethyl fumarate
CAS:Dimethyl fumarate (DMF) is an orally Nrf2 activator. Dimethyl fumarate has antimicrobial and anti-inflammatory activities. Cost-effective and quality-assured.Formula:C6H8O4Purity:90.51% - >99.99%Color and Shape:White To Off-White Powder White Crystalline PowderMolecular weight:144.13JMS-17-2 hydrochloride
CAS:JMS-17-2 hydrochloride: potent CX3CR1 blocker, IC50 of 0.32 nM, hinders breast cancer metastasis.Formula:C25H27Cl2N3OColor and Shape:SolidMolecular weight:456.41GNE0877
CAS:GNE0877 (GNE 0877) is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).Formula:C14H16F3N7Purity:98.01% - 99.97%Color and Shape:SolidMolecular weight:339.32Autophinib
CAS:Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay andFormula:C14H11ClN6O3Purity:99.25% - 99.41%Color and Shape:SolidMolecular weight:346.73STO-609
CAS:<p>STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.</p>Formula:C19H10N2O3Purity:97.14% - 98.8%Color and Shape:SolidMolecular weight:314.29Corynoxine
CAS:Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.Formula:C22H28N2O4Purity:96.83% - 99.93%Color and Shape:SolidMolecular weight:384.47ABT-751
CAS:ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.Formula:C18H17N3O4SPurity:98.84% - 99.50%Color and Shape:SolidMolecular weight:371.41Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Formula:C51H82O21Purity:99.51% - 99.63%Color and Shape:SolidMolecular weight:1031.18CHIR-99021
CAS:View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.Formula:C22H18Cl2N8Purity:97.94% - ≥95%Color and Shape:SolidMolecular weight:465.34Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Formula:C19H23NO4Purity:99.02% - 99.73%Color and Shape:White PowderMolecular weight:329.39Bergapten
CAS:<p>Bergapten (5-Methoxypsoralen), a psoralen, inhibits cell replication.</p>Formula:C12H8O4Purity:99.48% - ≥95%Color and Shape:Needles From Alcohol; Soln In Sulfuric Acid Is Yellow-Gold Physical Description Grayish-White Micr°Crystalline Powder Or Yellow Fluffy Solid (Ntp 1992)Molecular weight:216.19Pirarubicin HCl
CAS:Pirarubicin HCl, a less cardiotoxic doxorubicin analogue, hinders DNA replication and repairs by intercalating into DNA and inhibiting topoisomerase II.Formula:C32H38ClNO12Color and Shape:SolidMolecular weight:664.1IOWH-032
CAS:IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.Formula:C22H15Br2N3O4Purity:98.92% - ≥95%Color and Shape:SolidMolecular weight:545.18Pinocembrin
CAS:Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.Formula:C15H12O4Purity:99.61% - >99.99%Color and Shape:SolidMolecular weight:256.25MW-150 dihydrochloride dihydrate
CAS:MW-150: selective CNS-penetrant p38α MAPK inhibitor, orally active, Ki 101 nM, blocks MK2 phosphorylation in glia.Formula:C24H29Cl2N5O2Color and Shape:SolidMolecular weight:490.43Cediranib
CAS:Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.Formula:C25H27FN4O3Purity:97.21% - 99.94%Color and Shape:SolidMolecular weight:450.51SRT 1720
CAS:<p>SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.</p>Formula:C25H23N7OSPurity:98.84%Color and Shape:SolidMolecular weight:469.56Tubastatin A Hydrochloride
CAS:<p>Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM).</p>Formula:C20H21N3O2·HClPurity:97.24% - 99.15%Color and Shape:SolidMolecular weight:371.86Quizartinib
CAS:Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.Formula:C29H32N6O4SPurity:98% - 99.42%Color and Shape:SolidMolecular weight:560.67AZD1208
CAS:<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Formula:C21H21N3O2SPurity:97.24% - 99.83%Color and Shape:SolidMolecular weight:379.48
