Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
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Tanespimycin
CAS:75747-14-7
Tanespimycin (KOS 953) (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell …
Formula:
C31H43N3O8
Purity:
99.07% - 99.83%
Color and Shape:
Dark Purple Solid
Molecular weight:
585.69
Ref: TM-T6290
| 5mg | 45.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 94.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Sertindole
CAS:106516-24-9
Sertindole, atypical antipsychotic, targets D2, 5-HT1D, 5-HT2A, 5-HT2C receptors (Kds: 2.7, 20, 0.14, 6 nM).
Formula:
C24H26ClFN4O
Purity:
99.74%
Color and Shape:
Off-White To Pale Yellow Solid
Molecular weight:
440.94
Ref: TM-T5858
| 5mg | 49.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 270.00 € | ||
| 100mg | 367.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
QX77
CAS:1798331-92-6
QX77 is a chaperone-mediated autophagy (CMA) activator.
Formula:
C16H13ClN2O2
Purity:
98.38%
Color and Shape:
Solid
Molecular weight:
300.74
Ref: TM-T4663
| 1mg | 36.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 207.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 510.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Zoledronic Acid
CAS:118072-93-8
Zoledronic Acid (ZOL 446), a bisphosphonate, treats cancer-related fractures, hypercalcemia, bone pain, and osteoporosis.
Formula:
C5H10N2O7P2
Purity:
95.15% - 99.93%
Color and Shape:
White Crystalline Powder
Molecular weight:
272.09
Ref: TM-T6739
| 10mg | 38.00 € | ||
| 25mg | 51.00 € | ||
| 50mg | 83.00 € | ||
| 100mg | 122.00 € | ||
| 200mg | 176.00 € | ||
| 500mg | 296.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
VO-Ohpic trihydrate
CAS:476310-60-8
VO-Ohpic trihydrate (VO-Ohpic) is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 …
Formula:
C12H9N2O8V·3H2O·H
Purity:
100%
Color and Shape:
Solid
Molecular weight:
415.2
Ref: TM-T7012
| 5mg | 56.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 142.00 € | ||
| 50mg | 245.00 € | ||
| 100mg | 352.00 € | ||
| 200mg | 525.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
BGT226
CAS:915020-55-2
BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ …
Formula:
C28H25F3N6O2
Purity:
100% - 98.40%
Color and Shape:
Solid
Molecular weight:
534.53
Ref: TM-T6072L
| 1mg | 52.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 404.00 € | ||
| 50mg | 592.00 € | ||
| 100mg | 834.00 € | ||
| 1mL*10mM (DMSO) | 155.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
UNBS5162
CAS:956590-23-1
UNBS5162 (UNBS-5162) is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.
Formula:
C17H18N4O3
Purity:
98.37% - 99.97%
Color and Shape:
Solid
Molecular weight:
326.35
Ref: TM-T2477
| 1mg | 39.00 € | ||
| 2mg | 54.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 336.00 € | ||
| 100mg | 534.00 € | ||
| 200mg | 778.00 € | ||
| 500mg | 1,291.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Vinorelbine ditartrate
CAS:125317-39-7
Vinorelbine ditartrate (KW-2307) is a natural alkaloid and an anti-mitotic agent. Vinorelbine ditartrate has anti-tumor …
Formula:
C45H54N4O8·2C4H6O6
Purity:
98% - 99.86%
Color and Shape:
White To Off-White Crystalline Powder
Molecular weight:
1079.11
Ref: TM-T6213
| 5mg | 35.00 € | ||
| 10mg | 55.00 € | ||
| 25mg | 105.00 € | ||
| 50mg | 171.00 € | ||
| 100mg | 268.00 € | ||
| 500mg | 643.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Schisandrin
CAS:7432-28-2
Schisandrin (Wuweizi alcohol-A) is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects.
Formula:
C24H32O7
Purity:
98.97% - 99.32%
Color and Shape:
White Powder
Molecular weight:
432.51
Ref: TM-T2950
| 20mg | 54.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
MRT68921 HCl
CAS:2070014-87-6
MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 …
Formula:
C25H34N6O·HCl
Purity:
99.15% - 99.86%
Color and Shape:
Solid
Molecular weight:
471.04
Ref: TM-T5356
| 1mg | 44.00 € | ||
| 5mg | 65.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 333.00 € | ||
| 100mg | 416.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
NVP-AEW541
CAS:475489-16-8
NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and …
Formula:
C27H29N5O
Purity:
96.03% - 99.55%
Color and Shape:
Solid
Molecular weight:
439.55
Ref: TM-T6080
| 1mg | 48.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 267.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Oxyresveratrol
CAS:29700-22-9
1.
Formula:
C14H12O4
Purity:
98.09% - 99.69%
Color and Shape:
Yellow Solid
Molecular weight:
244.24
Ref: TM-T3S1068
| 1g | 173.00 € | ||
| 100mg | 37.00 € | ||
| 500mg | 109.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
BX795
CAS:702675-74-9
BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over …
Formula:
C23H26IN7O2S
Purity:
98% - 99.57%
Color and Shape:
Solid
Molecular weight:
591.47
Ref: TM-T1830
| 5mg | 58.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 206.00 € | ||
| 50mg | 335.00 € | ||
| 100mg | 502.00 € | ||
| 200mg | 727.00 € | ||
| 500mg | 1,096.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
ZSTK474
CAS:475110-96-4
PI3K Inhibitor ZSTK474 is an orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with …
Formula:
C19H21F2N7O2
Purity:
98.29% - 99.76%
Color and Shape:
White Powder
Molecular weight:
417.41
Ref: TM-T6168
| 25mg | 41.00 € | ||
| 50mg | 50.00 € | ||
| 100mg | 63.00 € | ||
| 200mg | 92.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
GW 4064
CAS:278779-30-9
GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).
Formula:
C28H22Cl3NO4
Purity:
97.47% - 99.94%
Color and Shape:
Solid
Molecular weight:
542.84
Ref: TM-T2233
| 5mg | 50.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 231.00 € | ||
| 100mg | 415.00 € | ||
| 200mg | 625.00 € | ||
| 500mg | 984.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Mirdametinib
CAS:391210-10-9
Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity.
Formula:
C16H14F3IN2O4
Purity:
99.18% - 99.63%
Color and Shape:
White Powder
Molecular weight:
482.19
Ref: TM-T6189
| 1g | 878.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 129.00 € | ||
| 50mg | 177.00 € | ||
| 100mg | 274.00 € | ||
| 200mg | 405.00 € | ||
| 500mg | 647.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
GSK621
CAS:1346607-05-3
GSK621 is a specific and potent AMPK activator.
Formula:
C26H20ClN3O5
Purity:
97.02% - 97.05%
Color and Shape:
Solid
Molecular weight:
489.91
Ref: TM-T6854
| 1mg | 54.00 € | ||
| 5mg | 105.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 346.00 € | ||
| 50mg | 510.00 € | ||
| 100mg | 727.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Tenovin-1
CAS:380315-80-0
Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which …
Formula:
C20H23N3O2S
Purity:
99.44%
Color and Shape:
Solid
Molecular weight:
369.48
Ref: TM-T1919
| 10mg | 54.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 108.00 € | ||
| 100mg | 188.00 € | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Cyclovirobuxine D
CAS:860-79-7
Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.
Formula:
C26H46N2O
Purity:
97.78% - 98%
Color and Shape:
Solid
Molecular weight:
402.66
Ref: TM-T2974
| 20mg | 54.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
Idelalisib
CAS:870281-82-6
Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 …
Formula:
C22H18FN7O
Purity:
98% - 99.94%
Color and Shape:
Solid
Molecular weight:
415.42
Ref: TM-T1894
| 5mg | 35.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 73.00 € | ||
| 50mg | 92.00 € | ||
| 100mg | 107.00 € | ||
| 200mg | 138.00 € | ||
| 500mg | 221.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 20 Nov 2024
