Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
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Azithromycin
CAS:83905-01-5
Azithromycin (CP 62993) is an antibiotic by inhibiting protein synthesis, used for the treatment of …
Formula:
C38H72N2O12
Purity:
99.88% - 99.9%
Color and Shape:
White To Off-White Solid Crystalline
Molecular weight:
748.98
Ref: TM-T6401
| 50mg | 60.00 € | ||
| 100mg | 91.00 € | ||
| 500mg | 205.00 € | ||
| 1mL*10mM (DMSO) | 68.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
UM-164
CAS:903564-48-7
UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, …
Formula:
C30H31F3N8O3S
Purity:
98.72% - 99.52%
Color and Shape:
Solid
Molecular weight:
640.68
Ref: TM-T4597
| 1mg | 35.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 277.00 € | ||
| 100mg | 409.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
E-64
CAS:66701-25-5
E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 …
Formula:
C15H27N5O5
Purity:
98% - 99.95%
Color and Shape:
White Solid
Molecular weight:
357.41
Ref: TM-T6037
| 2mg | 36.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 220.00 € | ||
| 100mg | 330.00 € | ||
| 500mg | 773.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
PF-06454589
CAS:1527473-30-8
PF-06454589 is a potent inhibitor of LRRK2.
Formula:
C14H16N6O
Purity:
96.29%
Color and Shape:
Solid
Molecular weight:
284.32
Ref: TM-T7729
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 131.00 € | ||
| 50mg | 193.00 € | ||
| 100mg | 299.00 € | ||
| 200mg | 431.00 € | ||
| 1mL*10mM (DMSO) | 54.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
SBI-0206965
CAS:1884220-36-3
SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 …
Formula:
C21H21BrN4O5
Purity:
98.86%
Color and Shape:
Solid
Molecular weight:
489.32
Ref: TM-T2128
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 268.00 € | ||
| 100mg | 416.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
OSI-027
CAS:936890-98-1
OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 …
Formula:
C21H22N6O3
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
406.44
Ref: TM-T6319
| 1mg | 41.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 137.00 € | ||
| 25mg | 244.00 € | ||
| 50mg | 383.00 € | ||
| 100mg | 557.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Omipalisib
CAS:1086062-66-9
Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.
Formula:
C25H17F2N5O3S
Purity:
98% - 99.8%
Color and Shape:
Solid
Molecular weight:
505.5
Ref: TM-T1861
| 5mg | 62.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 272.00 € | ||
| 100mg | 417.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
UNC1999
CAS:1431612-23-5
UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 …
Formula:
C33H43N7O2
Purity:
100% - 99.7%
Color and Shape:
Solid
Molecular weight:
569.74
Ref: TM-T3057
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 174.00 € | ||
| 50mg | 281.00 € | ||
| 100mg | 505.00 € | ||
| 500mg | 1,105.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Spautin-1
CAS:1262888-28-7
Spautin-1 is an autophagy inhibitor that can suppress the deubiquitination activity of ubiquitin-specific peptidase USP10 …
Formula:
C15H11F2N3
Purity:
97.69% - 98.99%
Color and Shape:
Solid
Molecular weight:
271.26
Ref: TM-T1937
| 2mg | 39.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 110.00 € | ||
| 50mg | 194.00 € | ||
| 100mg | 343.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
URMC-099
CAS:1229582-33-5
URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 - MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.
Formula:
C27H27N5
Purity:
98.43% - 99.32%
Color and Shape:
Solid
Molecular weight:
421.54
Ref: TM-T6057
| 5mg | 56.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 217.00 € | ||
| 100mg | 371.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
PF-543 hydrochloride
CAS:1706522-79-3
PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is …
Formula:
C27H32ClNO4S
Purity:
98.90% - 99.93%
Color and Shape:
Solid
Molecular weight:
502.1
Ref: TM-T8840
| 1mg | 39.00 € | ||
| 5mg | 75.00 € | ||
| 10mg | 132.00 € | ||
| 25mg | 232.00 € | ||
| 50mg | 313.00 € | ||
| 100mg | 479.00 € | ||
| 1mL*10mM (DMSO) | 103.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Berbamine dihydrochloride
CAS:6078-17-7
Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown …
Formula:
C37H42Cl2N2O6
Purity:
95% - 99.38%
Color and Shape:
Solid
Molecular weight:
681.65
Ref: TM-T2920
| 200mg | 35.00 € | ||
| 1mL*10mM (DMSO) | 41.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
AZD1208
CAS:1204144-28-4
AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency …
Formula:
C21H21N3O2S
Purity:
97.24% - 98.87%
Color and Shape:
Solid
Molecular weight:
379.48
Ref: TM-T2300
| 2mg | 38.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 117.00 € | ||
| 50mg | 210.00 € | ||
| 100mg | 370.00 € | ||
| 200mg | 487.00 € | ||
| 500mg | 778.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Tubastatin A Hydrochloride
CAS:1310693-92-5
Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM).
Formula:
C20H21N3O2·HCl
Purity:
97.24% - 99.25%
Color and Shape:
Solid
Molecular weight:
371.86
Ref: TM-T6161
| 5mg | 49.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 74.00 € | ||
| 50mg | 83.00 € | ||
| 100mg | 121.00 € | ||
| 200mg | 193.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Bergapten
CAS:484-20-8
Bergapten (5-Methoxypsoralen), a psoralen, inhibits cell replication.
Formula:
C12H8O4
Purity:
99.48% - ≥95%
Color and Shape:
Needles From Alcohol; Soln In Sulfuric Acid Is Yellow-Gold Physical Description Grayish-White Micr°Crystalline Powder Or Yellow Fluffy Solid (Ntp 1992)
Molecular weight:
216.19
Ref: TM-T2143
| 1g | 96.00 € | ||
| 100mg | 35.00 € | ||
| 500mg | 73.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Dimethyl fumarate
CAS:624-49-7
Dimethyl fumarate (DMF) is an orally Nrf2 activator. Dimethyl fumarate has antimicrobial and anti-inflammatory activities. …
Formula:
C6H8O4
Purity:
100% - 90.51%
Color and Shape:
White To Off-White Powder White Crystalline Powder
Molecular weight:
144.13
Ref: TM-T0492
| 500mg | 54.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Clematichinenoside AR
CAS:761425-93-8
Clematichinenoside AR is anti-inflammatory, immunosuppressive, and combats arthritis via PI3K/Akt and TNF-α pathways.
Formula:
C82H134O43
Purity:
99.49% - 99.69%
Color and Shape:
Solid
Molecular weight:
1807.92
Ref: TM-TN1507
| 1mg | 158.00 € | ||
| 5mg | 368.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Ginkgolide K
CAS:153355-70-5
Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.
Formula:
C20H22O9
Purity:
99.44% - 99.72%
Color and Shape:
Solid
Molecular weight:
406.38
Ref: TM-T8200
| 5mg | 86.00 € | ||
| 20mg | 234.00 € | ||
| 1mL*10mM (DMSO) | 108.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Telaglenastat
CAS:1439399-58-2
Telaglenastat (CB 839) (IC50 of 24 nM), an effective, specific, and oral inhibitor, which is …
Formula:
C26H24F3N7O3S
Purity:
100% - 99.89%
Color and Shape:
Solid
Molecular weight:
571.57
Ref: TM-T6797
| 1g | 1,105.00 € | ||
| 2mg | 38.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 207.00 € | ||
| 100mg | 343.00 € | ||
| 500mg | 807.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Fulvestrant
CAS:129453-61-8
Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an agonist of …
Formula:
C32H47F5O3S
Purity:
100% - 99.87%
Color and Shape:
White Powder
Molecular weight:
606.77
Ref: TM-T2146
| 10mg | 49.00 € | ||
| 25mg | 72.00 € | ||
| 50mg | 114.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
