Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1431 products of "Autophagy"
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BIX-01294
CAS:BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).Formula:C28H38N6O2Purity:98.58% - 99.64%Color and Shape:SolidMolecular weight:490.64PR-619
CAS:<p>PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective and quality-assured.</p>Formula:C7H5N5S2Purity:97.25% - >99.99%Color and Shape:SolidMolecular weight:223.28Rosiglitazone
CAS:<p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>Formula:C18H19N3O3SPurity:98.61% - 99.87%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.43AZD-3463
CAS:<p>AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.</p>Formula:C24H25ClN6OPurity:99.13%Color and Shape:SolidMolecular weight:448.95Schisandrin B
CAS:<p>Schisandrin B (Schisandrin B (Sch B)) has an antioxidant effect on rodent liver and heart.</p>Formula:C23H28O6Purity:99.02% - >99.99%Color and Shape:SolidMolecular weight:400.46(R)-(-)-Gossypol acetic acid
CAS:<p>(R)-(-)-Gossypol acetic acid binds Bcl-2, Bcl-xL, Mcl-1 (Ki: 0.32, 0.48, 0.18 μM); no BIR3/BID inhibition. Phase 2.</p>Formula:C30H30O8·C2H4O2Purity:98.88% - 99.5%Color and Shape:SolidMolecular weight:578.61Dantrolene sodium hemiheptahydrate
CAS:<p>Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium</p>Formula:C14H9N4NaO5·5H2OPurity:99.72%Color and Shape:Orange PowderMolecular weight:399.29Tripterin
CAS:Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.Formula:C29H38O4Purity:98.56% - 99.8%Color and Shape:Red Crystalline PowderMolecular weight:450.61Mito-LND
CAS:Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.Formula:C43H45BrCl2N3OPPurity:97.25% - 98.34%Color and Shape:SolidMolecular weight:801.62mTOR inhibitor-1
CAS:<p>C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.</p>Formula:C16H15BrN2O3Purity:99.43%Color and Shape:SolidMolecular weight:363.21AT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Formula:C19H23N7O2Purity:99.83% - 99.98%Color and Shape:SolidMolecular weight:381.43Osu03012
CAS:<p>Osu03012 (AR-12): oral celecoxib-derived PDK1 inhibitor with anticancer potential.</p>Formula:C26H19F3N4OPurity:97.95% - 99.22%Color and Shape:SolidMolecular weight:460.45Afzelin
CAS:<p>Afzelin (Kaempferol-3-O-rhamnoside) has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-</p>Formula:C21H20O10Purity:98.92% - 99.38%Color and Shape:SolidMolecular weight:432.38Icaritin
CAS:Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity.Formula:C21H20O6Purity:97.69% - 99.76%Color and Shape:SolidMolecular weight:368.38Cysteamine hydrochloride
CAS:<p>Cysteamine hydrochloride (Thioethanolamine Hydrochloride) is an agent for the treatment of nephropathic cystinosis and an antioxidant.</p>Formula:C2H7NS·HClPurity:99.34% - 99.87%Color and Shape:White Crystalline Powder With A Strong And Disagreeable SmellMolecular weight:113.61LY3009120
CAS:<p>LY3009120 (DP-4978) is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for A-raf, B-Raf, and C-Raf in A375 cells, respectively. Phase 1.</p>Formula:C23H29FN6OPurity:96.96% - ≥95%Color and Shape:SolidMolecular weight:424.51Divalproex Sodium
CAS:Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted byFormula:C8H16O2·C8H15O2·NaPurity:99.87%Color and Shape:A White Powder With A Characteristic OdorMolecular weight:310.41Cilengitide
CAS:Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.Formula:C27H40N8O7Purity:98% - 99.8%Color and Shape:SolidMolecular weight:588.66Calcineurin substrate acetate
<p>Calcineurin substrate acetate is from the regulatory RII subunit of cAMP-dependent protein kinase.</p>Formula:C94H154N28O31Purity:97.59%Color and Shape:SolidMolecular weight:2172.4Tamibarotene
CAS:Tamibarotene (Amnolake) is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplasticFormula:C22H25NO3Purity:98.55% - 99.73%Color and Shape:Crystalline SolidMolecular weight:351.44
