Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1431 products of "Autophagy"
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Bicyclol
CAS:<p>Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.</p>Formula:C19H18O9Purity:99.64% - 99.85%Color and Shape:SolidMolecular weight:390.34Peiminine
CAS:<p>1. Peiminine (Raddeanine) is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.</p>Formula:C27H43NO3Purity:99.52% - ≥95%Color and Shape:White PowderMolecular weight:429.64Oprozomib
CAS:<p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>Formula:C25H32N4O7SPurity:98% - 99.87%Color and Shape:SolidMolecular weight:532.61Ridaforolimus
CAS:<p>Ridaforolimus (AP23573) 是亲脂性大环内酯类抗生素雷帕霉素的小分子非前药类似物，具有潜在的抗肿瘤活性。它是一种有效和选择性的 mTOR 抑制剂，在 HT-1080 细胞中抑制 S6 磷酸化的 IC50值为 0.2 nM。</p>Formula:C53H84NO14PPurity:90.00% - 98.55%Color and Shape:Off-White SolidMolecular weight:990.21Oroxylin A
CAS:<p>Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.</p>Formula:C16H12O5Purity:98.72% - 99.55%Color and Shape:SolidMolecular weight:284.26SBI-0640756
CAS:SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.Formula:C23H14ClFN2O2Purity:99.75%Color and Shape:SolidMolecular weight:404.82Enzalutamide
CAS:<p>Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP).</p>Formula:C21H16F4N4O2SPurity:99% - 99.93%Color and Shape:SolidMolecular weight:464.44Arctigenin
CAS:<p>(-)-Arctigenin ((-)-Arctigenin) is found in burdock.</p>Formula:C21H24O6Purity:98% - 99.51%Color and Shape:SolidMolecular weight:372.41PRIMA-1
CAS:<p>PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.</p>Formula:C9H15NO3Purity:99.22%Color and Shape:SolidMolecular weight:185.22Fexaramine
CAS:<p>Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity compared to natural compounds.</p>Formula:C32H36N2O3Purity:98.87% - 99.61%Color and Shape:SolidMolecular weight:496.64GSK2656157
CAS:<p>GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay.</p>Formula:C23H21FN6OPurity:98.59% - >99.99%Color and Shape:SolidMolecular weight:416.45PD-166866
CAS:<p>PD-166866 is a selective FGFR tyrosine kinase inhibitor.</p>Formula:C20H24N6O3Purity:98.29%Color and Shape:SolidMolecular weight:396.44ICCB-19 hydrochloride
CAS:<p>ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.</p>Formula:C12H22ClN3OSPurity:99.3%Color and Shape:SolidMolecular weight:291.84Pictilisib
CAS:<p>Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).</p>Formula:C23H27N7O3S2Purity:98.69% - 99.97%Color and Shape:SolidMolecular weight:513.64Sedanolide
CAS:<p>Sedanolide is a natural phthalide first isolated from seed oil of the Umbelliferae family, including celery.</p>Formula:C12H18O2Purity:≥95% - ≥98%Color and Shape:SolidMolecular weight:194.27(-)-Epigallocatechin
CAS:<p>(-)-Epigallocatechin, the predominant flavonoid in green tea, possesses the unique ability to attach to unfolded native polypeptides, thereby inhibiting their</p>Formula:C15H14O7Purity:98.83% - >99.99%Color and Shape:White PowderMolecular weight:306.27SF1670
CAS:<p>SF1670 (PTPase CD45 Inhibitor) is a specific PTEN inhibitor with IC50 of 2 μM.</p>Formula:C19H17NO3Purity:98.25% - 98.54%Color and Shape:SolidMolecular weight:307.34Thiamet G
CAS:<p>Thiamet G is a selective O-GlcNAcase inhibitor (Ki=20 nM). The role of O-GlcNAcase is to remove O-GlcNAc from the modified protein. High-Quality, Low-Cost!</p>Formula:C9H16N2O4SPurity:99.06% - 99.98%Color and Shape:SolidMolecular weight:248.3Forskolin
CAS:<p>Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).</p>Formula:C22H34O7Purity:98.83% - 99.96%Color and Shape:Less Crystalline Solid Colorless Crystalline SolidMolecular weight:410.56-Thioguanine
CAS:6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.Formula:C5H5N5SPurity:98.75% - >99.99%Color and Shape:Odorless Or Almost Odorless Pale Yellow Crystalline PowderMolecular weight:167.19
