Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1431 products of "Autophagy"
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Chelerythrine
CAS:<p>1.</p>Formula:C21H18NO4Purity:98.36%Color and Shape:SolidMolecular weight:348.37Cinobufagin
CAS:<p>Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.</p>Formula:C26H34O6Purity:97.77% - 99.97%Color and Shape:SolidMolecular weight:442.54Fludrocortisone acetate
CAS:<p>Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and</p>Formula:C23H31FO6Purity:96.92% - 98.03%Color and Shape:Crystalline SolidMolecular weight:422.49Vinblastine sulfate
CAS:<p>Vinblastine sulfate (Vincaleukoblastine sulfate salt) can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).</p>Formula:C46H58N4O9·H2SO4Purity:97.81% - 99.68%Color and Shape:White PowderMolecular weight:909.06WYE-354
CAS:<p>WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).</p>Formula:C24H29N7O5Purity:97.86% - 99.61%Color and Shape:SolidMolecular weight:495.53(E)-Daporinad
CAS:(E)-Daporinad (FK866) is a highly specific, non-competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT） .Cost-effective and quality-assured.Formula:C24H29N3O2Purity:98.44% - >99.99%Color and Shape:SolidMolecular weight:391.51Licochalcone A
CAS:<p>Licochalcone A is a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch with obvious anti-cancer effects.</p>Formula:C21H22O4Purity:98.17% - 99.60%Color and Shape:White Crystalline PowderMolecular weight:338.4Tacrolimus
CAS:<p>Tacrolimus (Fujimycin) can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent protein</p>Formula:C44H69NO12Purity:98% - 99.94%Color and Shape:White Or Off-White Crystalline PowderMolecular weight:804.02N-Benzylpalmitamide
CAS:<p>N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the</p>Formula:C23H39NOPurity:97.08% - 99.77%Color and Shape:SolidMolecular weight:345.56Parthenolide
CAS:<p>Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with anti-inflammatory effect. Cost-effective and quality-assured.</p>Formula:C15H20O3Purity:98.19% - 99.46%Color and Shape:White To Pale Yellow Crystalline PowderMolecular weight:248.328-Chloroadenosine
CAS:<p>8-Chloroadenosine (NSC-354258) is a 5' AMP-activated protein kinase agonist potentially for the treatment of chronic lymphocytic leukemia.</p>Formula:C10H12ClN5O4Purity:98.75% - 99.84%Color and Shape:SolidMolecular weight:301.69Capivasertib
CAS:<p>Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity.</p>Formula:C21H25ClN6O2Purity:97.59% - 99.6%Color and Shape:SolidMolecular weight:428.92Dorsomorphin dihydrochloride
CAS:<p>Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on</p>Formula:C24H25N5O·2HClPurity:97.74% - 99.89%Color and Shape:SolidMolecular weight:472.413PO
CAS:<p>3PO inhibits PFKFB3 (IC50: 22.9 µM) and cancer cell growth (IC50: 1.4-24 µM), reducing glucose uptake and key cellular metabolites.</p>Formula:C13H10N2OPurity:99.56% - 99.67%Color and Shape:SolidMolecular weight:210.23Brazilin
CAS:<p>1.</p>Formula:C16H14O5Purity:98% - 99.83%Color and Shape:SolidMolecular weight:286.28PD168393
CAS:<p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>Formula:C17H13BrN4OPurity:99.13% - 99.83%Color and Shape:SolidMolecular weight:369.22Vemurafenib
CAS:<p>Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently.</p>Formula:C23H18ClF2N3O3SPurity:98% - 99.65%Color and Shape:SolidMolecular weight:489.92Everolimus
CAS:<p>Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.</p>Formula:C53H83NO14Purity:97.76% - 99.78%Color and Shape:Off-White To Light Yellow PowdMolecular weight:958.22Luminespib
CAS:<p>Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.</p>Formula:C26H31N3O5Purity:98% - 99.25%Color and Shape:SolidMolecular weight:465.54Sophocarpine
CAS:<p>Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>Formula:C15H22N2OPurity:99.89%Color and Shape:SolidMolecular weight:246.35
