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Endothelin Receptor

Endothelin Receptor

Endothelin receptors are GPCRs that mediate the effects of endothelins, potent vasoconstrictor peptides that play a significant role in vascular tone regulation, blood pressure control, and cell proliferation. Endothelin receptor antagonists are used in the treatment of conditions such as pulmonary arterial hypertension and heart failure. These receptors are also important targets in research on cardiovascular diseases and cancer. At CymitQuimica, we offer a selection of high-quality endothelin receptor modulators to support your research in cardiovascular biology, oncology, and vascular physiology.

Found 86 products of "Endothelin Receptor"

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  • JKC 302

    CAS:
    JKC 302 is an ET-A receptor antagonist that partially inhibits the contraction of tracheal rings in asthmatic rats induced by ET-1.
    Formula:C30H42N6O6
    Color and Shape:Solid
    Molecular weight:582.69

    Ref: TM-TP3818

    10mg
    To inquire
    50mg
    To inquire
  • Macitentan (n-butyl analogue)

    CAS:
    Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.
    Formula:C20H21Br2N5O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:587.29

    Ref: TM-T11935

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • IRL 2500

    CAS:
    IRL 2500 is an antagonist of Endothelin receptor with IC50s of 1.3 and 94 nM for Endothelin A receptor and Endothelin B receptor.
    Formula:C36H35N3O4
    Purity:99.36%
    Color and Shape:White Crystalline Solid
    Molecular weight:573.68

    Ref: TM-T15596

    2mg
    42.00€
    5mg
    60.00€
    10mg
    87.00€
    25mg
    172.00€
    50mg
    250.00€
    100mg
    350.00€
    1mL*10mM (DMSO)
    73.00€
  • Tezosentan

    CAS:
    Tezosentan is an antagonist of the endothelin receptor (pA2s: 9.5, 7.7 for ETA and ETB receptors, respectively).
    Formula:C27H27N9O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:605.63

    Ref: TM-T17064

    25mg
    2,025.00€
    50mg
    2,737.00€
    100mg
    3,565.00€
  • BQ-788

    CAS:
    BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.
    Formula:C34H51N5O7
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:641.8

    Ref: TM-T10595

    1mg
    137.00€
    2mg
    188.00€
    5mg
    329.00€
    10mg
    472.00€
    25mg
    753.00€
    50mg
    1,017.00€
    100mg
    1,378.00€
    500mg
    2,737.00€
    1mL*10mM (DMSO)
    360.00€
  • Patecibart

    CAS:

    Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).

    Purity:98%
    Color and Shape:Liquid

    Ref: TM-T81538

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    Discontinued
    1mg
    Discontinued
    5mg
    Discontinued
    50mg
    Discontinued
    Discontinued product