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Endothelin Receptor

Endothelin Receptor

Endothelin receptors are GPCRs that mediate the effects of endothelins, potent vasoconstrictor peptides that play a significant role in vascular tone regulation, blood pressure control, and cell proliferation. Endothelin receptor antagonists are used in the treatment of conditions such as pulmonary arterial hypertension and heart failure. These receptors are also important targets in research on cardiovascular diseases and cancer. At CymitQuimica, we offer a selection of high-quality endothelin receptor modulators to support your research in cardiovascular biology, oncology, and vascular physiology.

Found 76 products of "Endothelin Receptor"

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  • ANP(1-28) Acetate (human, porcine)
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    ANP(1-28) Acetate (human, porcine)

    CAS:
    <p>Carperitide acetate: 28-amino acid hormone from human heart, counters cardiac injury/stretch, reduces endothelin-1.</p>
    Formula:C129H207N45O41S3
    Purity:98.24%
    Color and Shape:Solid
    Molecular weight:3140.5

    Ref: TM-TP1220L

  • RO 46-8443
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    RO 46-8443

    CAS:
    <p>RO 46-8443: First non-peptide ETB receptor antagonist, &gt;2000-fold ETB selectivity in binding and function.</p>
    Formula:C31H35N3O8S
    Purity:98.77% - 99.77%
    Color and Shape:Solid
    Molecular weight:609.69

    Ref: TM-T3474

  • Ambrisentan
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    Ambrisentan

    CAS:
    <p>Ambrisentan, an endothelin antagonist for PAH, has a low risk of liver enzyme elevation, not linked to acute liver injury.</p>
    Formula:C22H22N2O4
    Purity:99.65% - 99.86%
    Color and Shape:Solid
    Molecular weight:378.42

    Ref: TM-T1655

  • Ro 46-2005
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    Ro 46-2005

    CAS:
    <p>Ro 46-2005: Synthetic non-peptide, blocks 125I-ET-1 at ETA receptors on human vascular cells (IC50: 220 nM).</p>
    Formula:C23H27N3O6S
    Purity:98.02% - 98.8%
    Color and Shape:Solid
    Molecular weight:473.54

    Ref: TM-T3194

  • Bosentan
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    Bosentan

    CAS:
    <p>Bosentan is a competitive endothelin receptor antagonist, used for treating pulmonary arterial hypertension.</p>
    Formula:C27H29N5O6S
    Purity:99.74% - 99.84%
    Color and Shape:Pale Yellow To Off-White Solid
    Molecular weight:551.614

    Ref: TM-T6264

  • Nebentan potassium
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    Nebentan potassium

    CAS:
    <p>Nebentan potassium (YM598) is an ETA receptor antagonist that inhibits pulmonary arterial hypertension and is used in the study of neurologic diseases.</p>
    Formula:C24H20KN5O5S
    Purity:99.05%
    Color and Shape:Solid
    Molecular weight:529.61

    Ref: TM-T36008

  • Zibotentan
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    Zibotentan

    CAS:
    <p>Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.</p>
    Formula:C19H16N6O4S
    Purity:97.00% - 97.02%
    Color and Shape:Solid
    Molecular weight:424.43

    Ref: TM-T6258

  • CH 141
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    CH 141

    CAS:
    <p>CH 141 is a new type of peripheral vasodilator.</p>
    Formula:C19H21N3O
    Color and Shape:Solid
    Molecular weight:307.39

    Ref: TM-T30859

  • ZD-1611
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    ZD-1611

    CAS:
    <p>ZD-1611 is an effective and selective ETA receptor antagonist. It is used for the research of ischemic stroke.</p>
    Formula:C22H24N4O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:456.51

    Ref: TM-T17287

  • WS 009B
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    WS 009B

    CAS:
    <p>WS 009B is an antagonist of the endothelin receptor.</p>
    Formula:C24H25NO11S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:535.52

    Ref: TM-T24081

  • Daglutril
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    Daglutril

    CAS:
    <p>Daglutril is a NEP/ECE inhibitor for treating hypertension, heart failure, and pulmonary issues, blocking big endothelin-1 conversion.</p>
    Formula:C31H38N2O6
    Color and Shape:Solid
    Molecular weight:534.64

    Ref: TM-T27119

  • WS 009A
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    WS 009A

    CAS:
    <p>WS 009A is an antagonist of the endothelin receptor.</p>
    Formula:C24H25NO10S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:519.52

    Ref: TM-T24053

  • ETA antagonist 1
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    ETA antagonist 1

    CAS:
    <p>ETA antagonist 1 is an antagonist of ETA selective (IC50 of 0.08 μM).</p>
    Formula:C20H25N3O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:387.5

    Ref: TM-T12157

  • Aminaftone
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    Aminaftone

    CAS:
    <p>Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis.</p>
    Formula:C18H15NO4
    Purity:96.31% - 99.39%
    Color and Shape:Solid
    Molecular weight:309.32

    Ref: TM-T14219

  • Atrasentan hydrochloride
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    Atrasentan hydrochloride

    CAS:
    <p>Atrasentan hydrochloride (ABT-627 hydrochloride) is an antagonist of the endothelin receptor(IC50 = 55.1 μM for ETA).</p>
    Formula:C29H39ClN2O6
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:547.08

    Ref: TM-TQ0270

  • PD-156707
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    PD-156707

    CAS:
    <p>PD-156707 is a selective antagonist of endothelin A receptor.</p>
    Formula:C28H26NaO9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:529.497

    Ref: TM-T28343

  • CI 1020
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    CI 1020

    CAS:
    <p>endothelin-A receptor (ETA) antagonist</p>
    Formula:C28H26O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:506.5

    Ref: TM-T22663

  • TBC3711
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    TBC3711

    CAS:
    <p>TBC3711 is an endothelin receptor modulator. It is used for the research of endothelin-mediated disorders.</p>
    Formula:C20H21N3O5S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:447.53

    Ref: TM-T15232

  • BMS-193884
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    BMS-193884

    CAS:
    <p>BMS-193884 is an oral endothelin antagonist for the treatment of congestive heart failure (CHF) and pulmonary arterial hypertension.</p>
    Formula:C20H17N3O4S
    Color and Shape:Solid
    Molecular weight:395.43

    Ref: TM-T30501

  • PD-159020
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    PD-159020

    CAS:
    <p>PD-159020 is a non-selective antagonist of ETA/ETB(hETA and hETB with IC50s of 30 and 50 nM , respectively).</p>
    Formula:C32H25NO8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:551.54

    Ref: TM-T12382