Endothelin Receptor
Endothelin receptors are GPCRs that mediate the effects of endothelins, potent vasoconstrictor peptides that play a significant role in vascular tone regulation, blood pressure control, and cell proliferation. Endothelin receptor antagonists are used in the treatment of conditions such as pulmonary arterial hypertension and heart failure. These receptors are also important targets in research on cardiovascular diseases and cancer. At CymitQuimica, we offer a selection of high-quality endothelin receptor modulators to support your research in cardiovascular biology, oncology, and vascular physiology.
Found 85 products for "Endothelin Receptor".
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Sparsentan
CAS:Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM,Formula:C32H40N4O5SPurity:97.94% - 99.88%Color and Shape:White SolidMolecular weight:592.75Ref: TM-T5355
2mg37.00€5mg55.00€1mL*10mM (DMSO)73.00€10mg89.00€25mg161.00€50mg245.00€100mg360.00€200mg512.00€BMS 182874 hydrochloride
CAS:BMS 182874 hydrochloride is a nonpeptide endothelin (El) receptor antagonist.Formula:C17H20ClN3O3SPurity:97.01%Color and Shape:Yellow SolidMolecular weight:381.88Ref: TM-T21790
1mg77.00€2mg92.00€5mg140.00€1mL*10mM (DMSO)146.00€10mg205.00€25mg343.00€50mg477.00€100mg665.00€200mg897.00€Endothelin-2 (49-69), human
CAS:Endothelin-2 (49-69), human (Human endothelin-2) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.Formula:C115H160N26O32S4Purity:98.26%Color and Shape:White SolidMolecular weight:2546.92Atrasentan sodium
CAS:Atrasentan (ABT-627) is an oral ETA receptor blocker with potential cancer-fighting properties, inhibiting angiogenesis and tumor growth.Formula:C29H37N2NaO6Color and Shape:SolidMolecular weight:532.61Sitaxsentan sodium
CAS:Sitaxsentan sodium (TBC11251 sodium salt) is a highly selective antagonist of endothelin A receptors.Formula:C18H14ClN2O6S2·NaPurity:98.39% - 99.01%Color and Shape:Red SolidMolecular weight:476.89BQ-123
CAS:BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.Formula:C31H42N6O7Purity:98.36% - 99.22%Color and Shape:White SolidMolecular weight:610.7Bosentan (hydrate)
CAS:Bosentan hydrate (Ro 47-0203) is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.Formula:C27H29N5O6S·H2OPurity:99.31% - 99.86%Color and Shape:SolidMolecular weight:569.63ANP(1-28) Acetate (human, porcine)
CAS:Carperitide acetate: 28-amino acid hormone from human heart, counters cardiac injury/stretch, reduces endothelin-1.Formula:C129H207N45O41S3Purity:98.24%Color and Shape:SolidMolecular weight:3140.5RO 46-8443
CAS:RO 46-8443: First non-peptide ETB receptor antagonist, >2000-fold ETB selectivity in binding and function.Formula:C31H35N3O8SPurity:98.77% - 99.77%Color and Shape:White SolidMolecular weight:609.69Ambrisentan
CAS:Ambrisentan, an endothelin antagonist for PAH, has a low risk of liver enzyme elevation, not linked to acute liver injury.Formula:C22H22N2O4Purity:99.65% - 99.86%Color and Shape:White SolidMolecular weight:378.42Ro 46-2005
CAS:Ro 46-2005: Synthetic non-peptide, blocks 125I-ET-1 at ETA receptors on human vascular cells (IC50: 220 nM).Formula:C23H27N3O6SPurity:98.02% - 98.8%Color and Shape:SolidMolecular weight:473.54Bosentan
CAS:Bosentan is a competitive endothelin receptor antagonist, used for treating pulmonary arterial hypertension.Formula:C27H29N5O6SPurity:99.74% - 99.84%Color and Shape:SolidMolecular weight:551.614Ref: TM-T6264
10mg35.00€25mg52.00€50mg77.00€1mL*10mM (DMSO)84.00€100mg120.00€200mg195.00€500mg294.00€Nebentan potassium
CAS:Nebentan potassium (YM598) is an ETA receptor antagonist that inhibits pulmonary arterial hypertension and is used in the study of neurologic diseases.Formula:C24H20KN5O5SPurity:99.42%Color and Shape:SolidMolecular weight:529.61Ref: TM-T36008
1mg52.00€2mg77.00€5mg111.00€1mL*10mM (DMSO)133.00€10mg177.00€25mg313.00€50mg502.00€100mg680.00€200mg888.00€Zibotentan
CAS:Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.Formula:C19H16N6O4SPurity:97.00% - 97.02%Color and Shape:White SolidMolecular weight:424.43ABT-546
CAS:ABT-546 is a potent, selective endothelin ETA receptor antagonist, Ki 0.46 nM for [125I]ET-1 binding.Formula:C30H48N2O6Purity:98%Color and Shape:SolidMolecular weight:532.71Avosentan
CAS:Avosentan（Ro 67-0565; SPP-301） is a potent endothelin receptor (ETA) antagonist.Cost-effective and quality-assured.Formula:C23H21N5O5SPurity:98.31% - 99.47%Color and Shape:SolidMolecular weight:479.51Atrasentan hydrochloride
CAS:Atrasentan hydrochloride (ABT-627 hydrochloride) is an antagonist of the endothelin receptor(IC50 = 55.1 μM for ETA).Formula:C29H39ClN2O6Purity:99.75%Color and Shape:SolidMolecular weight:547.08TBC3711
CAS:TBC3711 is an endothelin receptor modulator. It is used for the research of endothelin-mediated disorders.Formula:C20H21N3O5S2Purity:98%Color and Shape:SolidMolecular weight:447.53CI 1020
CAS:endothelin-A receptor (ETA) antagonistFormula:C28H26O9Purity:98%Color and Shape:SolidMolecular weight:506.5PD-156707
CAS:PD-156707 is a selective antagonist of endothelin A receptor.Formula:C28H26NaO9Purity:98%Color and Shape:SolidMolecular weight:529.497
