Endothelin Receptor
Endothelin receptors are GPCRs that mediate the effects of endothelins, potent vasoconstrictor peptides that play a significant role in vascular tone regulation, blood pressure control, and cell proliferation. Endothelin receptor antagonists are used in the treatment of conditions such as pulmonary arterial hypertension and heart failure. These receptors are also important targets in research on cardiovascular diseases and cancer. At CymitQuimica, we offer a selection of high-quality endothelin receptor modulators to support your research in cardiovascular biology, oncology, and vascular physiology.
Found 86 products of "Endothelin Receptor"
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Atrasentan sodium
CAS:Atrasentan (ABT-627) is an oral ETA receptor blocker with potential cancer-fighting properties, inhibiting angiogenesis and tumor growth.Formula:C29H37N2NaO6Color and Shape:SolidMolecular weight:532.61Ro 46-2005
CAS:Ro 46-2005: Synthetic non-peptide, blocks 125I-ET-1 at ETA receptors on human vascular cells (IC50: 220 nM).Formula:C23H27N3O6SPurity:98.02% - 98.8%Color and Shape:SolidMolecular weight:473.54RO 46-8443
CAS:RO 46-8443: First non-peptide ETB receptor antagonist, >2000-fold ETB selectivity in binding and function.Formula:C31H35N3O8SPurity:98.77% - 99.77%Color and Shape:SolidMolecular weight:609.69Bosentan (hydrate)
CAS:Bosentan hydrate (Ro 47-0203) is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.Formula:C27H29N5O6S·H2OPurity:99.31% - 99.86%Color and Shape:White PowderMolecular weight:569.63Ambrisentan
CAS:Ambrisentan, an endothelin antagonist for PAH, has a low risk of liver enzyme elevation, not linked to acute liver injury.Formula:C22H22N2O4Purity:99.65% - 99.86%Color and Shape:SolidMolecular weight:378.42Atrasentan
CAS:Atrasentan (ABT-627) is an endothelin receptor antagonist that can inhibit the activity of ETA.Cost-effective and quality-assured.Formula:C29H38N2O6Purity:97.65% - 99.08%Color and Shape:SolidMolecular weight:510.62Ref: TM-TQ0259
1mg46.00€5mg90.00€10mg130.00€25mg250.00€50mg356.00€100mg580.00€200mg798.00€1mL*10mM (DMSO)109.00€Aprocitentan
CAS:Aprocitentan (ACT-132577) is ETA and ETB antagonist .Formula:C16H14Br2N6O4SPurity:99.17%Color and Shape:SolidMolecular weight:546.19Ref: TM-T7817
1mg58.00€5mg116.00€10mg170.00€25mg311.00€50mg439.00€100mg655.00€200mg887.00€1mL*10mM (DMSO)142.00€Sparsentan
CAS:Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM,Formula:C32H40N4O5SPurity:97.94% - 98.69%Color and Shape:SolidMolecular weight:592.75Ref: TM-T5355
2mg37.00€5mg55.00€10mg89.00€25mg161.00€50mg245.00€100mg360.00€200mg512.00€1mL*10mM (DMSO)73.00€BMS 182874 hydrochloride
CAS:BMS 182874 hydrochloride is a nonpeptide endothelin (El) receptor antagonist.Formula:C17H20ClN3O3SPurity:97.01%Color and Shape:SolidMolecular weight:381.88Ref: TM-T21790
1mg77.00€2mg92.00€5mg140.00€10mg205.00€25mg343.00€50mg477.00€100mg665.00€200mg897.00€1mL*10mM (DMSO)146.00€ANP(1-28) Acetate (human, porcine)
CAS:Carperitide acetate: 28-amino acid hormone from human heart, counters cardiac injury/stretch, reduces endothelin-1.Formula:C129H207N45O41S3Purity:98.24%Color and Shape:SolidMolecular weight:3140.5Ref: TM-TP1220L
1mg185.00€5mg459.00€10mg657.00€25mg1,026.00€50mg1,388.00€100mg1,872.00€200mg2,527.00€Macitentan
CAS:Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).Formula:C19H20Br2N6O4SPurity:98% - >99.99%Color and Shape:SolidMolecular weight:588.27Endothelin-2 (49-69), human
CAS:Endothelin-2 (49-69), human (Human endothelin-2) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.Formula:C115H160N26O32S4Purity:98.26%Color and Shape:SolidMolecular weight:2546.92Nebentan potassium
CAS:Nebentan potassium (YM598) is an ETA receptor antagonist that inhibits pulmonary arterial hypertension and is used in the study of neurologic diseases.Formula:C24H20KN5O5SPurity:99.05%Color and Shape:SolidMolecular weight:529.61Ref: TM-T36008
1mg52.00€2mg77.00€5mg111.00€10mg177.00€25mg313.00€50mg502.00€100mg680.00€200mg888.00€1mL*10mM (DMSO)133.00€Zibotentan
CAS:Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.Formula:C19H16N6O4SPurity:97.00% - 97.02%Color and Shape:SolidMolecular weight:424.43TBC3711
CAS:TBC3711 is an endothelin receptor modulator. It is used for the research of endothelin-mediated disorders.Formula:C20H21N3O5S2Purity:98%Color and Shape:SolidMolecular weight:447.53ZD-1611
CAS:ZD-1611 is an effective and selective ETA receptor antagonist. It is used for the research of ischemic stroke.Formula:C22H24N4O5SPurity:98%Color and Shape:SolidMolecular weight:456.51CH 141
CAS:CH 141 is a new type of peripheral vasodilator.Formula:C19H21N3OColor and Shape:SolidMolecular weight:307.39ABT-546
CAS:ABT-546 is a potent, selective endothelin ETA receptor antagonist, Ki 0.46 nM for [125I]ET-1 binding.Formula:C30H48N2O6Purity:98%Color and Shape:SolidMolecular weight:532.71BMS-193884
CAS:BMS-193884 is an oral endothelin antagonist for the treatment of congestive heart failure (CHF) and pulmonary arterial hypertension.Formula:C20H17N3O4SColor and Shape:SolidMolecular weight:395.43CI 1020
CAS:endothelin-A receptor (ETA) antagonistFormula:C28H26O9Purity:98%Color and Shape:SolidMolecular weight:506.5
