Endothelin Receptor
Endothelin receptors are GPCRs that mediate the effects of endothelins, potent vasoconstrictor peptides that play a significant role in vascular tone regulation, blood pressure control, and cell proliferation. Endothelin receptor antagonists are used in the treatment of conditions such as pulmonary arterial hypertension and heart failure. These receptors are also important targets in research on cardiovascular diseases and cancer. At CymitQuimica, we offer a selection of high-quality endothelin receptor modulators to support your research in cardiovascular biology, oncology, and vascular physiology.
Found 85 products for "Endothelin Receptor".
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BMS-193884
CAS:BMS-193884 is an oral endothelin antagonist for the treatment of congestive heart failure (CHF) and pulmonary arterial hypertension.Formula:C20H17N3O4SColor and Shape:SolidMolecular weight:395.43CH 141
CAS:CH 141 is a new type of peripheral vasodilator.Formula:C19H21N3OColor and Shape:SolidMolecular weight:307.39WS 009B
CAS:WS 009B is an antagonist of the endothelin receptor.Formula:C24H25NO11SPurity:98%Color and Shape:SolidMolecular weight:535.52Daglutril
CAS:Daglutril is a NEP/ECE inhibitor for treating hypertension, heart failure, and pulmonary issues, blocking big endothelin-1 conversion.Formula:C31H38N2O6Color and Shape:SolidMolecular weight:534.64ETA antagonist 1
CAS:ETA antagonist 1 is an antagonist of ETA selective (IC50 of 0.08 μM).Formula:C20H25N3O3SPurity:98%Color and Shape:SolidMolecular weight:387.5WS 009A
CAS:WS 009A is an antagonist of the endothelin receptor.Formula:C24H25NO10SPurity:98%Color and Shape:SolidMolecular weight:519.52PD-159020
CAS:PD-159020 is a non-selective antagonist of ETA/ETB(hETA and hETB with IC50s of 30 and 50 nM , respectively).Formula:C32H25NO8Purity:98%Color and Shape:SolidMolecular weight:551.54ZD-1611
CAS:ZD-1611 is an effective and selective ETA receptor antagonist. It is used for the research of ischemic stroke.Formula:C22H24N4O5SPurity:98%Color and Shape:SolidMolecular weight:456.51FR 139317
CAS:highly potent and selective ETA endothelin receptor antagonistFormula:C33H44N6O5Purity:98%Color and Shape:SolidMolecular weight:604.74Aminaftone
CAS:Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis.Formula:C18H15NO4Purity:96.31% - 99.39%Color and Shape:SolidMolecular weight:309.32Sitaxsentan
CAS:Sitaxsentan (TBC-11251), a selective ETA receptor antagonist, prevents vasoconstriction by blocking endothelin.Formula:C18H15ClN2O6S2Purity:97.99% - 98.71%Color and Shape:SolidMolecular weight:454.9BMS 182874
CAS:BMS 182874: Oral ETA antagonist, IC50=0.150 μM, Ki=0.055 μM, lowers hypertension in rats.Formula:C17H19N3O3SPurity:99.73%Color and Shape:Yellow SolidMolecular weight:345.42Edonentan
CAS:Edonentan is A potent endothelin A (ETA) receptor antagonist that can be used to study heart failure.Formula:C28H32N4O5SPurity:98.07% - 99.13%Color and Shape:White SolidMolecular weight:536.64SB-209670
CAS:SB-209670 is a selective endothelin receptor antagonist that inhibits the activity of ET(B) receptors in rat vascular endothelium and vascular smooth muscle.Formula:C29H28O9Purity:98.29% - 99.40%Color and Shape:SolidMolecular weight:520.53Ref: TM-T34541
1mg315.00€5mg745.00€1mL*10mM (DMSO)755.00€10mg1,018.00€25mg1,431.00€50mg1,783.00€100mg2,250.00€500mg4,410.00€L-749329
CAS:L-749329 is a ligand of ET(A) and ET(B) endothelin receptor.Formula:C28H29NO8SPurity:98%Color and Shape:SolidMolecular weight:539.6Clazosentan
CAS:Clazosentan (Ro 61-1790) is a selective ET_A receptor antagonist that inhibits ET-1 vasoconstriction and prevents cerebral vasospasm.Formula:C25H23N9O6SPurity:95.39% - >99.99%Color and Shape:SolidMolecular weight:577.57Ref: TM-T64084
1mg71.00€5mg167.00€1mL*10mM (DMSO)205.00€10mg258.00€25mg565.00€50mg888.00€100mg1,161.00€JKC 302
CAS:JKC 302 is an ET-A receptor antagonist that partially inhibits the contraction of tracheal rings in asthmatic rats induced by ET-1.Formula:C30H42N6O6Color and Shape:SolidMolecular weight:582.69K-8794
CAS:K-8794 is an orally active and selective endothelin receptor ETB antagonist that can be utilized in cardiovascular disease research.Formula:C36H38N6O6SColor and Shape:SolidMolecular weight:682.789BMS-248360
CAS:BMS-248360: Oral dual hAT1/hETA antagonist with Kis of 10nM & 1.9nM, respectively; treats hypertension.Formula:C36H45N5O5SPurity:98%Color and Shape:SolidMolecular weight:659.84Edonentan hydrate
CAS:Edonentan (BMS 207940) hydrate effectively blocks the endothelin A (ETA) receptor as a potent and selective antagonist, featuring a K i of 10 pM. It exhibits complete (100%) oral bioavailability in rats [1].Formula:C28H34N4O6SColor and Shape:SolidMolecular weight:554.66
