Endothelin Receptor
Endothelin receptors are GPCRs that mediate the effects of endothelins, potent vasoconstrictor peptides that play a significant role in vascular tone regulation, blood pressure control, and cell proliferation. Endothelin receptor antagonists are used in the treatment of conditions such as pulmonary arterial hypertension and heart failure. These receptors are also important targets in research on cardiovascular diseases and cancer. At CymitQuimica, we offer a selection of high-quality endothelin receptor modulators to support your research in cardiovascular biology, oncology, and vascular physiology.
Found 76 products of "Endothelin Receptor"
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ABT-546
CAS:<p>ABT-546 is a potent, selective endothelin ETA receptor antagonist, Ki 0.46 nM for [125I]ET-1 binding.</p>Formula:C30H48N2O6Purity:98%Color and Shape:SolidMolecular weight:532.71Avosentan
CAS:<p>Avosentan（Ro 67-0565; SPP-301） is a potent endothelin receptor (ETA) antagonist.Cost-effective and quality-assured.</p>Formula:C23H21N5O5SPurity:98.31% - 99.47%Color and Shape:SolidMolecular weight:479.51FR 139317
CAS:<p>highly potent and selective ETA endothelin receptor antagonist</p>Formula:C33H44N6O5Purity:98%Color and Shape:SolidMolecular weight:604.74Edonentan
CAS:<p>Edonentan is A potent endothelin A (ETA) receptor antagonist that can be used to study heart failure.</p>Formula:C28H32N4O5SPurity:98.07% - 99.6%Color and Shape:SolidMolecular weight:536.64Sitaxsentan
CAS:<p>Sitaxsentan (TBC-11251), a selective ETA receptor antagonist, prevents vasoconstriction by blocking endothelin.</p>Formula:C18H15ClN2O6S2Purity:97.99% - 98.71%Color and Shape:SolidMolecular weight:454.9SB-209670
CAS:<p>SB-209670 is a selective endothelin receptor antagonist that inhibits the activity of ET(B) receptors in rat vascular endothelium and vascular smooth muscle.</p>Formula:C29H28O9Purity:97.80% - 99.40%Color and Shape:SolidMolecular weight:520.53BMS 182874
CAS:<p>BMS 182874: Oral ETA antagonist, IC50=0.150 μM, Ki=0.055 μM, lowers hypertension in rats.</p>Formula:C17H19N3O3SPurity:98.38%Color and Shape:SolidMolecular weight:345.42L-749329
CAS:<p>L-749329 is a ligand of ET(A) and ET(B) endothelin receptor.</p>Formula:C28H29NO8SPurity:98%Color and Shape:SolidMolecular weight:539.6Clazosentan
CAS:<p>Clazosentan (Ro 61-1790) is a selective ET_A receptor antagonist that inhibits ET-1 vasoconstriction and prevents cerebral vasospasm.</p>Formula:C25H23N9O6SPurity:95.39% - >99.99%Color and Shape:SolidMolecular weight:577.57BMS-248360
CAS:<p>BMS-248360: Oral dual hAT1/hETA antagonist with Kis of 10nM & 1.9nM, respectively; treats hypertension.</p>Formula:C36H45N5O5SPurity:98%Color and Shape:SolidMolecular weight:659.84Tezosentan
CAS:<p>Tezosentan is an antagonist of the endothelin receptor (pA2s: 9.5, 7.7 for ETA and ETB receptors, respectively).</p>Formula:C27H27N9O6SPurity:98%Color and Shape:SolidMolecular weight:605.63K-8794
CAS:<p>K-8794 is an orally active and selective endothelin receptor ETB antagonist that can be utilized in cardiovascular disease research.</p>Formula:C36H38N6O6SColor and Shape:SolidMolecular weight:682.789IRL 2500
CAS:<p>IRL 2500 is an antagonist of Endothelin receptor with IC50s of 1.3 and 94 nM for Endothelin A receptor and Endothelin B receptor.</p>Formula:C36H35N3O4Purity:99.36%Color and Shape:White Crystalline SolidMolecular weight:573.68Macitentan (n-butyl analogue)
CAS:<p>Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.</p>Formula:C20H21Br2N5O4SPurity:98%Color and Shape:SolidMolecular weight:587.29BQ-788
CAS:<p>BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.</p>Formula:C34H51N5O7Purity:98.81%Color and Shape:SolidMolecular weight:641.8Patecibart
CAS:<p>Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).</p>Purity:98%Color and Shape:Liquid
