Endothelin Receptor
Endothelin receptors are GPCRs that mediate the effects of endothelins, potent vasoconstrictor peptides that play a significant role in vascular tone regulation, blood pressure control, and cell proliferation. Endothelin receptor antagonists are used in the treatment of conditions such as pulmonary arterial hypertension and heart failure. These receptors are also important targets in research on cardiovascular diseases and cancer. At CymitQuimica, we offer a selection of high-quality endothelin receptor modulators to support your research in cardiovascular biology, oncology, and vascular physiology.
Found 86 products of "Endothelin Receptor"
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IRL-3630
CAS:IRL 3460 is an enantiomer.Formula:C31H40N4O6SPurity:98%Color and Shape:SolidMolecular weight:596.74Atrial Natriuretic Peptide (ANP) (1-28), rat
CAS:Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.Formula:C128H205N45O39S2Purity:98%Color and Shape:SolidMolecular weight:3062.41ACT-373898
CAS:ACT-373898 is a metabolite of the endothelin (ET) receptor type A (ETA) and ETBdual antagonist macitentan .1
Formula:C15H17BrN4O5SColor and Shape:SolidMolecular weight:445.29[Lys4] Sarafotoxin S6c
CAS:[Lys4] Sarafotoxin S6c: potent partial endothelin receptor agonist; causes pig coronary contraction, EC50=1.5 nM.Formula:C105H153N27O36S5Color and Shape:SolidMolecular weight:2529.82[Asn18] Endothelin-1, human
CAS:[Asn18] Endothelin-1, human, a peptide, represents a predominant isoform of Endothelin, significantly contributing to the regulation of vascular function [1].Formula:C109H164N26O31S5Molecular weight:2494.96Atrial natriuretic peptide (3-28) (human)
CAS:Atrial natriuretic peptide (3-28) (human) (ANP (3-28) (human)), a peptide hormone produced by the atrial myocardium, plays a critical role in the regulation ofFormula:C118H187N43O36S3Purity:98%Color and Shape:SolidMolecular weight:2880.21IRL-1038
CAS:ETB endothelin receptor antagonistFormula:C68H92N14O15S2Purity:98%Color and Shape:SolidMolecular weight:1409.67Sarafotoxin S6b
CAS:non-selective endothelin receptor agonistFormula:C110H163N27O34S5Purity:98%Color and Shape:SolidMolecular weight:2567.96Sarafotoxin S6c
CAS:Highly selective ETB endothelin receptor agonist (Ki values are 0.29 and 28000 nM at ETB and ETA receptors respectively).Formula:C103H147N27O37S5Purity:98%Color and Shape:SolidMolecular weight:2516PD 142893
CAS:PD 142893 is a functional endothelin-stimulated vasoconstriction antagonist.Formula:C50H65N7O10Purity:98%Color and Shape:SolidMolecular weight:924.09BQ-3020 ammonium
BQ-3020 ammonium, a selective endothelin receptor (ET B receptor) agonist, demonstrates inhibition of [125 I] ET-1 binding to ET B receptors with an IC50 of 0.2Formula:C96H140N20O25S·xNH3Purity:98%Color and Shape:SolidMolecular weight:2006.32 (free base)IRL-1620
CAS:IRL-1620 is an effective and selective agonist of endothelin receptor type B (ETB) (Ki: 16 pM).Formula:C86H117N17O27Purity:98%Color and Shape:SolidMolecular weight:1820.974Sarafotoxin S6a
CAS:Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.Formula:C105H156N28O34S5Purity:98%Color and Shape:SolidMolecular weight:2514.85Endothelin-3 (Rat,Human) (TFA)
Endothelin-3 (Rat, Human) (TFA) is a 21-amino acid vasoactive peptide of endothelial origi, an agonist for the endothelin receptor type B (EDNRB).Formula:C123H169F3N26O35S4·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:2757.07 (free base)Macitentan
CAS:Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).Formula:C19H20Br2N6O4SPurity:98% - >99.99%Color and Shape:SolidMolecular weight:588.27BQ-123
CAS:BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.Formula:C31H42N6O7Purity:99.22% - ≥95%Color and Shape:SolidMolecular weight:610.7Darusentan
CAS:Darusentan (Lu-135252) is a potent inhibitor of endothelin signaling and function in both large and small arteriesFormula:C22H22N2O6Purity:98.72%Color and Shape:SolidMolecular weight:410.43Ref: TM-T5458
2mg43.00€5mg65.00€10mg100.00€25mg173.00€50mg288.00€100mg414.00€200mg583.00€1mL*10mM (DMSO)67.00€BQ-788 sodium salt
CAS:BQ-788 sodium salt is a potent and selective antagonist of ETB receptor(ETB receptors with an IC50 of 1.2 nM in human Girrardi heart cells).Formula:C34H51N5NaO7Color and Shape:SolidMolecular weight:664.8Aprocitentan
CAS:Aprocitentan (ACT-132577) is ETA and ETB antagonist .Formula:C16H14Br2N6O4SPurity:99.17%Color and Shape:SolidMolecular weight:546.19Ref: TM-T7817
1mg58.00€5mg116.00€10mg170.00€25mg311.00€50mg439.00€100mg655.00€200mg887.00€1mL*10mM (DMSO)142.00€Ambrisentan sodium
CAS:Ambrosentan (BSF 208075) sodium is a selective and oral effective antagonist of ET type A receptor ( ETAR ).Formula:C22H21N2NaO4Color and Shape:SolidMolecular weight:400.41
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