Endothelin Receptor
Endothelin receptors are GPCRs that mediate the effects of endothelins, potent vasoconstrictor peptides that play a significant role in vascular tone regulation, blood pressure control, and cell proliferation. Endothelin receptor antagonists are used in the treatment of conditions such as pulmonary arterial hypertension and heart failure. These receptors are also important targets in research on cardiovascular diseases and cancer. At CymitQuimica, we offer a selection of high-quality endothelin receptor modulators to support your research in cardiovascular biology, oncology, and vascular physiology.
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Atrasentan hydrochloride
CAS:195733-43-8
Atrasentan hydrochloride (ABT-627 hydrochloride) is an antagonist of the endothelin receptor(IC50 = 55.1 μM for …
Formula:
C29H39ClN2O6
Purity:
98.64%
Color and Shape:
Solid
Molecular weight:
547.08
Ref: TM-TQ0270
| 2mg | 41.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 159.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 74.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Aminaftone
CAS:14748-94-8
Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to …
Formula:
C18H15NO4
Purity:
96.31% - 99.39%
Color and Shape:
Solid
Molecular weight:
309.32
Ref: TM-T14219
| 1mg | 325.00 € | ||
| 5mg | 901.00 € | ||
| 10mg | 1,114.00 € | ||
| 25mg | 1,476.00 € | ||
| 50mg | 1,839.00 € | ||
| 100mg | 2,322.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
BMS 182874
CAS:153042-42-3
BMS 182874: Oral ETA antagonist, IC50=0.150 μM, Ki=0.055 μM, lowers hypertension in rats.
Formula:
C17H19N3O3S
Purity:
98.38%
Color and Shape:
Solid
Molecular weight:
345.42
Ref: TM-T26841
| 1mg | 73.00 € | ||
| 5mg | 157.00 € | ||
| 10mg | 244.00 € | ||
| 25mg | 422.00 € | ||
| 50mg | 601.00 € | ||
| 100mg | 827.00 € | ||
| 500mg | 1,687.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Avosentan
CAS:290815-26-8
Avosentan(Ro 67-0565; SPP-301) is a potent endothelin receptor (ETA) antagonist.Cost-effective and quality-assured.
Formula:
C23H21N5O5S
Purity:
98.25% - 99.47%
Color and Shape:
Solid
Molecular weight:
479.51
Ref: TM-TQ0282
| 1mg | 40.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 104.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 539.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Sitaxsentan
CAS:184036-34-8
Sitaxsentan (TBC-11251), a selective ETA receptor antagonist, prevents vasoconstriction by blocking endothelin.
Formula:
C18H15ClN2O6S2
Purity:
97.99% - 99.34%
Color and Shape:
Solid
Molecular weight:
454.9
Ref: TM-T12924
| 1mg | 88.00 € | ||
| 5mg | 198.00 € | ||
| 10mg | 322.00 € | ||
| 25mg | 499.00 € | ||
| 50mg | 678.00 € | ||
| 100mg | 922.00 € | ||
| 500mg | 1,838.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
SB-209670
CAS:157659-79-5
SB-209670 is a selective endothelin receptor antagonist that inhibits the activity of ET(B) receptors in …
Formula:
C29H28O9
Purity:
97.39% - 99.24%
Color and Shape:
Solid
Molecular weight:
520.53
Ref: TM-T34541
| 1mg | 325.00 € | ||
| 5mg | 769.00 € | ||
| 10mg | 1,054.00 € | ||
| 25mg | 1,476.00 € | ||
| 50mg | 1,846.00 € | ||
| 100mg | 2,320.00 € | ||
| 500mg | 4,577.00 € | ||
| 1mL*10mM (DMSO) | 791.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Edonentan
CAS:210891-04-6
Edonentan is A potent endothelin A (ETA) receptor antagonist that can be used to study …
Formula:
C28H32N4O5S
Purity:
98.78% - 99%
Color and Shape:
Solid
Molecular weight:
536.64
Ref: TM-T31605
| 1mg | 939.00 € | ||
| 5mg | 1,850.00 € | ||
| 25mg | 2,404.00 € | ||
| 50mg | 2,784.00 € | ||
| 100mg | 3,737.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
Clazosentan
CAS:180384-56-9
Clazosentan (Ro 61-1790) is a selective ET_A receptor antagonist that inhibits ET-1 vasoconstriction and prevents …
Formula:
C25H23N9O6S
Purity:
95.39% - 99.43%
Color and Shape:
Liquid
Molecular weight:
577.57
Ref: TM-T64084
| 1mg | 90.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 322.00 € | ||
| 25mg | 707.00 € | ||
| 50mg | 1,163.00 € | ||
| 100mg | 1,475.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
IRL 2500
CAS:169545-27-1
IRL 2500 is an antagonist of Endothelin receptor with IC50s of 1.3 and 94 nM …
Formula:
C36H35N3O4
Purity:
98.29%
Color and Shape:
White Crystalline Solid
Molecular weight:
573.68
Ref: TM-T15596
| 1mg | 49.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 151.00 € | ||
| 25mg | 294.00 € | ||
| 50mg | 428.00 € | ||
| 100mg | 602.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
BQ-788
CAS:173326-37-9
BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation …
Formula:
C34H51N5O7
Purity:
98.67%
Color and Shape:
Solid
Molecular weight:
641.8
Ref: TM-T10595
| 1mg | 134.00 € | ||
| 2mg | 184.00 € | ||
| 5mg | 327.00 € | ||
| 10mg | 467.00 € | ||
| 25mg | 746.00 € | ||
| 50mg | 1,006.00 € | ||
| 100mg | 1,363.00 € | ||
| 500mg | 2,674.00 € | ||
| 1mL*10mM (DMSO) | 358.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
