CymitQuimica logo
Sigma receptor

Sigma receptor

Sigma receptors are unique binding sites that, unlike traditional GPCRs, do not fit into the classical categories of receptor proteins. They are involved in modulating neurotransmitter systems and have been implicated in various neurological and psychiatric disorders. Sigma receptors are also associated with cell survival, and their ligands are being explored for therapeutic applications in neuroprotection, cancer, and pain management. At CymitQuimica, we offer a selection of high-quality sigma receptor modulators to support your research in neuroscience, oncology, and receptor biology.

Found 48 products for "Sigma receptor".

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Sigma-1 receptor antagonist 2
    Targetmol
    + Info

    Sigma-1 receptor antagonist 2

    CAS:
    Sigma-1 receptor antagonist 2 is a more potent and selective antagonist of sigma 1 receptor (σ1 R, Ki = 3.88 nM) than σ2 receptor (Ki = 1288 nM).
    Formula:C20H26ClN3O2
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:375.89

    Ref: TM-T12911

    1mg
    46.00€
    5mg
    96.00€
    1mL*10mM (DMSO)
    105.00€
    10mg
    161.00€
    25mg
    261.00€
    50mg
    371.00€
    100mg
    504.00€
    200mg
    675.00€
  • WLB-89462
    Targetmol
    + Info

    WLB-89462

    CAS:
    WLB-89462 (Compound 20c) is a selective σ2 receptor ligand with a K i of 13 nM, exhibiting neuroprotective properties and the ability to ameliorate Aβ peptide-
    Formula:C21H29N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:399.49

    Ref: TM-T79666

    5mg
    To inquire
    50mg
    To inquire
  • Sigma-1 receptor antagonist 3
    Targetmol
    + Info

    Sigma-1 receptor antagonist 3

    CAS:
    Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor(Ki = 1239 nM).
    Formula:C19H23ClFN3O
    Purity:99.95%
    Color and Shape:White Solid
    Molecular weight:363.86

    Ref: TM-T12912

    1mg
    84.00€
    5mg
    177.00€
    10mg
    289.00€
    25mg
    477.00€
    50mg
    647.00€
    100mg
    858.00€
  • Sigma-2 Radioligand 2
    Targetmol
    + Info

    Sigma-2 Radioligand 2

    CAS:
    Sigma-2 Radioligand 2 (compound 4) exhibits low nanomolar affinity for the σ2 receptor (Ki=2.30 nM) and high subtype selectivity (Ki(σ1)/Ki(σ2) > 1500).
    Formula:C23H28FN3O3
    Color and Shape:Solid
    Molecular weight:413.49

    Ref: TM-T200974

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • Opipramol dihydrochloride
    Targetmol
    + Info

    Opipramol dihydrochloride

    CAS:
    Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) primarily functioning as a sigma (σ) receptor agonist. It interacts effectively with sigma recognition sites, having a Ki value of 50 nM. Opipramol is applicable in the study of generalized anxiety disorder (GAD).
    Formula:C23H31Cl2N3O
    Color and Shape:Solid
    Molecular weight:436.418

    Ref: TM-T204660

    10mg
    To inquire
    50mg
    To inquire
  • UMB24
    Targetmol
    + Info

    UMB24

    CAS:
    UMB24 is an effective antagonist of the σ2 receptor, exhibiting dissociation constants (Ki values) of 170 nM for the σ2 receptor and 322 nM for the σ1 receptor. This compound mitigates cocaine-induced convulsions and hyperactivity without causing mortality.
    Formula:C17H21N3
    Color and Shape:Solid
    Molecular weight:267.37

    Ref: TM-T201855

    10mg
    To inquire
    50mg
    To inquire
  • BD-1047
    Targetmol
    + Info

    BD-1047

    CAS:
    BD-1047 is a selective functional antagonist of sigma receptors. It can alleviate climbing behavior induced by Apomorphine and head twitching caused by Phencyclidine.
    Formula:C13H20Cl2N2
    Color and Shape:Solid
    Molecular weight:275.217

    Ref: TM-T205677

    10mg
    To inquire
    50mg
    To inquire
  • Sigma-1 receptor antagonist 6
    Targetmol
    + Info

    Sigma-1 receptor antagonist 6

    CAS:
    Sigma-1 receptor antagonist 6 (Compound 12), a σ1R antagonist, demonstrates significant antiallodynic effects by targeting the Sigma-1 receptor (σ1R). This compound is effective in animal models for neuropathic pain, particularly for reducing mechanical allodynia caused by paclitaxel.
    Formula:C32H34N6
    Color and Shape:Solid
    Molecular weight:502.65

    Ref: TM-T89901

    10mg
    To inquire
    50mg
    To inquire