Sigma receptor
Sigma receptors are unique binding sites that, unlike traditional GPCRs, do not fit into the classical categories of receptor proteins. They are involved in modulating neurotransmitter systems and have been implicated in various neurological and psychiatric disorders. Sigma receptors are also associated with cell survival, and their ligands are being explored for therapeutic applications in neuroprotection, cancer, and pain management. At CymitQuimica, we offer a selection of high-quality sigma receptor modulators to support your research in neuroscience, oncology, and receptor biology.
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Sigma-LIGAND-1
CAS:139652-01-0
Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM, 19 nM …
Formula:
C27H33NO4
Purity:
100%
Color and Shape:
Solid
Molecular weight:
435.56
Ref: TM-T13510
| 1mg | 64.00 € | ||
| 5mg | 149.00 € | ||
| 10mg | 215.00 € | ||
| 25mg | 335.00 € | ||
| 50mg | 452.00 € | ||
| 100mg | 620.00 € | ||
| 200mg | 835.00 € | ||
| 1mL*10mM (DMSO) | 172.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
PD 144418
CAS:154130-99-1
PD 144418 displays potential antipsychotic activity.
Formula:
C18H22N2O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
282.38
Ref: TM-T16445
| 25mg | 698.00 € | ||
| 50mg | 908.00 € | ||
| 100mg | 1,369.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
OPC-14523 hydrochloride
CAS:145969-31-9
OPC-14523 hydrochloride, an oral sigma/5-HT1A agonist, shows potent antidepressant activity with strong receptor affinity.
Formula:
C23H29Cl2N3O2
Purity:
99.70%
Color and Shape:
Liquid
Molecular weight:
450.4
Ref: TM-T62711
| 5mg | 922.00 € | ||
| 10mg | 1,224.00 € | ||
| 25mg | 1,539.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € | ||
| 1mL*10mM (DMSO) | 977.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
S1R agonist 1 hydrochloride
CAS:242487-82-7
S1R Agonist 1 (Compound 6b) hydrochloride is a selective S1R agonist, displaying K i values …
Formula:
C20H26ClNO
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
331.88
Ref: TM-T78086
| 2mg | 52.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Sigma-1 receptor antagonist 2
CAS:1639220-15-7
Sigma-1 receptor antagonist 2 is a more potent and selective antagonist of sigma 1 receptor …
Formula:
C20H26ClN3O2
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
375.89
Ref: TM-T12911
| 1mg | 64.00 € | ||
| 5mg | 145.00 € | ||
| 10mg | 235.00 € | ||
| 25mg | 394.00 € | ||
| 50mg | 562.00 € | ||
| 100mg | 758.00 € | ||
| 200mg | 1,017.00 € | ||
| 1mL*10mM (DMSO) | 160.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Sigma-1 receptor antagonist 3
CAS:1639220-17-9
Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor …
Formula:
C19H23ClFN3O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
363.86
Ref: TM-T12912
| 1mg | 88.00 € | ||
| 5mg | 187.00 € | ||
| 10mg | 305.00 € | ||
| 25mg | 502.00 € | ||
| 50mg | 682.00 € | ||
| 100mg | 905.00 € |
Estimated delivery in United States, on Monday 5 May 2025
WLB-89462
CAS:2849471-75-4
WLB-89462 (Compound 20c) is a selective σ2 receptor ligand with a K i of 13 …
Formula:
C21H29N5O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
399.49
Ref: TM-T79666
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 5 May 2025
Sigma-1 receptor antagonist 1
CAS:1639220-19-1
Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor.
Formula:
C19H23Cl2N3O
Purity:
99.81%
Color and Shape:
Solid
Molecular weight:
380.31
Ref: TM-T12910
| 1mg | 64.00 € | ||
| 5mg | 145.00 € | ||
| 10mg | 226.00 € | ||
| 25mg | 379.00 € | ||
| 50mg | 538.00 € | ||
| 100mg | 730.00 € | ||
| 200mg | 938.00 € |
Estimated delivery in United States, on Monday 5 May 2025
UMB24
CAS:1033-69-8
UMB24 is an effective antagonist of the σ2 receptor, exhibiting dissociation constants (Ki values) of …
Formula:
C17H21N3
Color and Shape:
Liquid
Molecular weight:
267.37
Ref: TM-T201855
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Jun 2025
Sigma-2 Radioligand 2
CAS:2860554-31-8
Sigma-2 Radioligand 2 (compound 4) exhibits low nanomolar affinity for the σ2 receptor (Ki=2.30 nM) …
Formula:
C23H28FN3O3
Color and Shape:
Liquid
Molecular weight:
413.49
Ref: TM-T200974
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Jun 2025
Sigma-1 receptor antagonist 6
CAS:1335032-28-4
Sigma-1 receptor antagonist 6 (Compound 12), a σ1R antagonist, demonstrates significant antiallodynic effects by targeting …
Formula:
C32H34N6
Color and Shape:
Liquid
Molecular weight:
502.65
Ref: TM-T89901
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Jun 2025
