CaSR
The calcium-sensing receptor (CaSR) is a GPCR that plays a vital role in maintaining calcium homeostasis by regulating parathyroid hormone secretion and calcium reabsorption in the kidneys. CaSR is also involved in various other physiological processes, including bone metabolism and vascular function. Modulators of CaSR are used in the treatment of conditions such as hyperparathyroidism, osteoporosis, and cardiovascular diseases. At CymitQuimica, we provide a selection of high-quality CaSR modulators to support your research in calcium metabolism, endocrinology, and bone health.
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Strontium ranelate
CAS:135459-87-9
Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for …
Formula:
C12H6N2O8S·2Sr
Purity:
100%
Color and Shape:
Crystalline Solid
Molecular weight:
513.49
Ref: TM-T1641
| 10mg | 38.00 € | ||
| 25mg | 52.00 € | ||
| 50mg | 86.00 € | ||
| 100mg | 114.00 € | ||
| 200mg | 183.00 € | ||
| 500mg | 422.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Evocalcet
CAS:870964-67-3
Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).
Formula:
C24H26N2O2
Purity:
98.41% - 99.83%
Color and Shape:
Solid
Molecular weight:
374.48
Ref: TM-T15261
| 5mg | 38.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 153.00 € | ||
| 100mg | 225.00 € | ||
| 200mg | 326.00 € | ||
| 1mL*10mM (DMSO) | 41.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Upacicalcet HCl
Upacicalcet HCl, a calcium mimetic, reduces blood PTH by targeting parathyroid receptors; treats secondary hyperparathyroidism.
Formula:
C11H15Cl2N3O6S
Purity:
98.56%
Color and Shape:
Soild
Molecular weight:
388.22
Ref: TM-T29067L
| 1mg | 172.00 € | ||
| 5mg | 424.00 € | ||
| 10mg | 621.00 € | ||
| 25mg | 989.00 € | ||
| 50mg | 1,337.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
AC265347
CAS:1253901-26-6
AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity …
Formula:
C17H17NOS
Purity:
100%
Color and Shape:
Solid
Molecular weight:
283.39
Ref: TM-T29541
| 1mg | 38.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 341.00 € | ||
| 100mg | 503.00 € | ||
| 500mg | 1,076.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Poly-D-lysine hydrobromide (MW 30000-70000)
CAS:27964-99-4
Poly-D-lysine hydrobromide (MW 30000-70000) (Poly-D-lysine HBr) is a peptide CaSR agonist that removes proteinase K-resistant …
Formula:
(C6H14N2O2)x·xHBr
Color and Shape:
Liquid
Molecular weight:
227.102
Ref: TM-T40363
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 150.00 € | ||
| 100mg | 212.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
Cinacalcet hydrochloride
CAS:364782-34-3
Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity …
Formula:
C22H23ClF3N
Purity:
99.9% - 99.94%
Color and Shape:
Off-White To Tan Solid
Molecular weight:
393.87
Ref: TM-T2406
| 10mg | 51.00 € | ||
| 25mg | 69.00 € | ||
| 50mg | 86.00 € | ||
| 100mg | 143.00 € | ||
| 200mg | 182.00 € | ||
| 500mg | 304.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
NPS2390
CAS:226878-01-9
NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 …
Formula:
C19H21N3O
Purity:
97.13%
Color and Shape:
Solid
Molecular weight:
307.39
Ref: TM-T8457
| 5mg | 41.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 107.00 € | ||
| 50mg | 181.00 € | ||
| 100mg | 296.00 € | ||
| 200mg | 408.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Etelcalcetide hydrochloride
CAS:1334237-71-6
Etelcalcetide HCl, a synthetic peptide modulator of CaSR, lowers PTH in dialysis patients with secondary …
Formula:
C38H73N21O10S2HCl
Purity:
100%
Color and Shape:
Solid
Molecular weight:
1353.33
Ref: TM-TP1236
| 1mg | 35.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 325.00 € | ||
| 100mg | 535.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Cinacalcet
CAS:226256-56-0
Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular …
Formula:
C22H22F3N
Purity:
99.48%
Color and Shape:
Yellow Oil
Molecular weight:
357.41
Ref: TM-T8403
| 10mg | 50.00 € | ||
| 25mg | 70.00 € | ||
| 50mg | 87.00 € | ||
| 100mg | 143.00 € | ||
| 500mg | 347.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
NPS-2143 hydrochloride
CAS:324523-20-8
NPS-2143 hydrochloride (NPS-2143 HCL) is a selective potent calcium ion-sensing receptor antagonist.
Formula:
C24H25ClN2O2·HCl
Purity:
99.22% - 99.38%
Color and Shape:
Solid
Molecular weight:
445.38
Ref: TM-T4967
| 1mg | 45.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 128.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 337.00 € | ||
| 100mg | 493.00 € | ||
| 1mL*10mM (DMSO) | 90.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Ligustroflavone
CAS:260413-62-5
Ligustroflavone (Nuezhenoside) has anti-inflammatory activity.
Formula:
C33H40O18
Purity:
98% - 99.51%
Color and Shape:
Solid
Molecular weight:
724.66
Ref: TM-T3802
| 1mg | 52.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 258.00 € | ||
| 50mg | 370.00 € | ||
| 1mL*10mM (DMSO) | 153.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Gadolinium chloride
CAS:10138-52-0
Gadolinium chloride is a calcium-sensing receptor (CaSR) agonist
Formula:
Cl3Gd
Purity:
98%
Color and Shape:
White Crystalline Solid
Molecular weight:
263.61
Ref: TM-T22795
| 25mg | 48.00 € | ||
| 50mg | 58.00 € | ||
| 100mg | 90.00 € | ||
| 200mg | 124.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Ronacaleret HCl
CAS:702686-96-2
Ronacaleret HCl (SB-751689) is a small molecule CaSR antagonist for the treatment of endocrine and …
Formula:
C25H32ClF2NO4
Purity:
99.58%
Color and Shape:
Solid
Molecular weight:
483.98
Ref: TM-T34385
| 1mg | 271.00 € | ||
| 5mg | 666.00 € | ||
| 10mg | 917.00 € | ||
| 25mg | 1,380.00 € | ||
| 50mg | 1,839.00 € | ||
| 100mg | 2,536.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Tecalcet Hydrochloride
CAS:177172-49-5
Tecalcet Hydrochloride, an allosteric CaSR modulator, enhances extracellular Ca2+ sensitivity.
Formula:
C18H23Cl2NO
Purity:
99.44%
Color and Shape:
Solid
Molecular weight:
340.29
Ref: TM-T13918
| 2mg | 35.00 € | ||
| 5mg | 49.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 151.00 € | ||
| 50mg | 238.00 € | ||
| 100mg | 347.00 € | ||
| 200mg | To inquire | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
NPS-2143
CAS:284035-33-2
NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.
Formula:
C24H25ClN2O2
Purity:
98.24%
Color and Shape:
Solid
Molecular weight:
408.92
Ref: TM-T1730
| 5mg | 51.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 150.00 € | ||
| 50mg | 217.00 € | ||
| 100mg | 325.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Calhex 231 hydrochloride
CAS:2387505-78-2
Calhex 231 hydrochloride, a CaSR antagonist, may treat diabetic cardiomyopathy; IC50 is 0.39 μM in …
Formula:
C25H28Cl2N2O
Color and Shape:
Solid
Molecular weight:
443.41
Ref: TM-T10666
| 2mg | 95.00 € | ||
| 5mg | 144.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Calindol hydrochloride
CAS:729610-18-8
Calindol (hydrochloride) is a positive allosteric modulator (PAM) of calcimimetic calcium-sensing receptor (CaSR) with an …
Formula:
C21H21ClN2
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
336.86
Ref: TM-T21758
| 1mg | 52.00 € | ||
| 5mg | 148.00 € | ||
| 10mg | 243.00 € | ||
| 25mg | 511.00 € | ||
| 50mg | 812.00 € | ||
| 100mg | 1,301.00 € | ||
| 200mg | 1,754.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
CaSR antagonist-1
CAS:1219811-83-2
CaSR Antagonist-1 is a potent inhibitor of the calcium-sensing receptor (CaSR) with an inhibitory concentration …
Formula:
C29H24FN3O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
497.58
Ref: TM-T79023
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Mar 2025
SB-423562
CAS:351490-27-2
SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.
Formula:
C26H32N2O4
Purity:
98.64%
Color and Shape:
Solid
Molecular weight:
436.54
Ref: TM-T12846
| 1mg | 38.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 214.00 € | ||
| 50mg | 325.00 € | ||
| 100mg | 450.00 € | ||
| 200mg | 616.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Tuesday 1 Apr 2025
