CaSR
The calcium-sensing receptor (CaSR) is a GPCR that plays a vital role in maintaining calcium homeostasis by regulating parathyroid hormone secretion and calcium reabsorption in the kidneys. CaSR is also involved in various other physiological processes, including bone metabolism and vascular function. Modulators of CaSR are used in the treatment of conditions such as hyperparathyroidism, osteoporosis, and cardiovascular diseases. At CymitQuimica, we provide a selection of high-quality CaSR modulators to support your research in calcium metabolism, endocrinology, and bone health.
Found 34 products of "CaSR"
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Strontium ranelate
CAS:Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis and can slow the course of osteoarthritis of the knee.Formula:C12H6N2O8S·2SrPurity:98.97%Color and Shape:Crystalline SolidMolecular weight:513.49AC265347
CAS:AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity for the study of neuroblastoma.Formula:C17H17NOSPurity:>99.99%Color and Shape:SolidMolecular weight:283.39Evocalcet
CAS:Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).Formula:C24H26N2O2Purity:98.88% - 99.68%Color and Shape:SolidMolecular weight:374.48Etelcalcetide
CAS:Etelcalcetide (AMG 416), a synthetic peptide CaSR activator, treats secondary hyperparathyroidism in hemodialysis patients.Formula:C38H73N21O10S2Purity:98%Color and Shape:SolidMolecular weight:1048.26Poly-D-lysine hydrobromide (MW 1000-5000)
Poly-D-lysine hydrobromide (PDLHB) (MW 1000-5000) is a synthetically produced polymeric substrate widely used in neural cell culture. Additionally, Poly-D-lysine hydrobromide acts as a CaSR agonist peptide.Color and Shape:Odour SolidPoly-D-lysine hydrobromide (MW 150000-300000)
Poly-D-lysine hydrobromide (MW 150000-300000) enhances neural cell adhesion in culture and acts as a calcium-sensing receptor agonist peptide in research.Color and Shape:Odour SolidUpacicalcet HCl
Upacicalcet HCl, a calcium mimetic, reduces blood PTH by targeting parathyroid receptors; treats secondary hyperparathyroidism.Formula:C11H15Cl2N3O6SPurity:98.56%Color and Shape:SoildMolecular weight:388.22γ-Glu-Abu TFA
Gamma-Glu-AbuTFA is the TFA salt form of Gamma-Glu-Abu. This compound acts as an agonist for the calcium sensing receptor (CaSR), activating CaSR in HEK-293 cells with an EC50 of 0.21 μM.Formula:C11H17F3N2O7Color and Shape:SolidMolecular weight:346.26G-Glu-Val
CAS:G-Glu-Val (γ-glutamyl-L-valine, H-Glu-Val -OH), a flavour-regulating dipeptide, is a major contributor to "mellow".
Formula:C10H18N2O5Color and Shape:SolidMolecular weight:246.26Calcium-Sensing Receptor Antagonists I
CAS:Calcium-Sensing Receptor Antagonists I functions as an antagonist to the parathyroid hormone receptors that sense calcium.Formula:C23H24N2O2Color and Shape:SolidMolecular weight:360.45Cinacalcet
CAS:Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular disease .Formula:C22H22F3NPurity:99.48%Color and Shape:Yellow OilMolecular weight:357.41NPS-2143 hydrochloride
CAS:NPS-2143 hydrochloride (NPS-2143 HCL) is a selective potent calcium ion-sensing receptor antagonist.Formula:C24H25ClN2O2·HClPurity:99.38% - 99.67%Color and Shape:SolidMolecular weight:445.38Ref: TM-T4967
1mg43.00€2mg56.00€5mg87.00€10mg119.00€25mg203.00€50mg320.00€100mg475.00€1mL*10mM (DMSO)95.00€TNCA
CAS:TNCA (Lycoperodine-1) is a high-affinity CaSR ligand (CaSRL) with co-agonist activity.Formula:C12H12N2O2Purity:97.33% - 97.73%Color and Shape:SolidMolecular weight:216.24Ligustroflavone
CAS:Ligustroflavone (Nuezhenoside) has anti-inflammatory activity.Formula:C33H40O18Purity:98% - 99.92%Color and Shape:SolidMolecular weight:724.66Gadolinium chloride
CAS:Gadolinium chloride is a calcium-sensing receptor (CaSR) agonistFormula:Cl3GdPurity:98%Color and Shape:White Crystalline SolidMolecular weight:263.61Cinacalcet hydrochloride
CAS:Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-Formula:C22H23ClF3NPurity:99.96% - >99.99%Color and Shape:Off-White To Tan SolidMolecular weight:393.87Ref: TM-T2406
10mg50.00€25mg70.00€50mg88.00€100mg144.00€200mg185.00€500mg309.00€1mL*10mM (DMSO)52.00€Etelcalcetide hydrochloride
CAS:Etelcalcetide HCl, a synthetic peptide modulator of CaSR, lowers PTH in dialysis patients with secondary hyperparathyroidism.Formula:C38H73N21O10S2HClPurity:>99.99%Color and Shape:SolidMolecular weight:1353.33NPS2390
CAS:NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)Formula:C19H21N3OPurity:97.13%Color and Shape:SolidMolecular weight:307.39Tecalcet Free Base
CAS:Tecalcet Free Base is an oral calcium receptor agonistFormula:C18H22ClNOColor and Shape:SolidMolecular weight:303.83SB-423562 HCl
CAS:SB-423562 is a calcium-sensing receptor antagonist.Formula:C26H33ClN2O4Purity:98%Color and Shape:SolidMolecular weight:473
