CaSR
The calcium-sensing receptor (CaSR) is a GPCR that plays a vital role in maintaining calcium homeostasis by regulating parathyroid hormone secretion and calcium reabsorption in the kidneys. CaSR is also involved in various other physiological processes, including bone metabolism and vascular function. Modulators of CaSR are used in the treatment of conditions such as hyperparathyroidism, osteoporosis, and cardiovascular diseases. At CymitQuimica, we provide a selection of high-quality CaSR modulators to support your research in calcium metabolism, endocrinology, and bone health.
Found 31 products for "CaSR".
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AC265347
CAS:AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity for the study of neuroblastoma.Formula:C17H17NOSPurity:99.92%Color and Shape:SolidMolecular weight:283.39Strontium ranelate
CAS:Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis and can slow the course of osteoarthritis of the knee.Formula:C12H6N2O8S·2SrPurity:98.97%Color and Shape:White SolidMolecular weight:513.49Evocalcet
CAS:Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).Formula:C24H26N2O2Purity:98.88% - 99.68%Color and Shape:SolidMolecular weight:374.4754Upacicalcet HCl
Upacicalcet HCl, a calcium mimetic, reduces blood PTH by targeting parathyroid receptors; treats secondary hyperparathyroidism.Formula:C11H15Cl2N3O6SPurity:>99.99%Color and Shape:Yellow SolidMolecular weight:388.22Etelcalcetide
CAS:Etelcalcetide (AMG 416), a synthetic peptide CaSR activator, treats secondary hyperparathyroidism in hemodialysis patients.Formula:C38H73N21O10S2Purity:98%Color and Shape:SolidMolecular weight:1048.251γ-Glu-Abu TFA
Gamma-Glu-AbuTFA is the TFA salt form of Gamma-Glu-Abu. This compound acts as an agonist for the calcium sensing receptor (CaSR), activating CaSR in HEK-293 cells with an EC50 of 0.21 μM.Formula:C11H17F3N2O7Color and Shape:SolidMolecular weight:346.26Calcium-Sensing Receptor Antagonists I
CAS:Calcium-Sensing Receptor Antagonists I functions as an antagonist to the parathyroid hormone receptors that sense calcium.Formula:C23H24N2O2Color and Shape:SolidMolecular weight:360.4489Cinacalcet
CAS:Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular disease .Formula:C22H22F3NPurity:99.48%Color and Shape:Transparent LiquidMolecular weight:360.4305NPS-2143 hydrochloride
CAS:NPS-2143 hydrochloride (NPS-2143 HCL) is a selective potent calcium ion-sensing receptor antagonist.Formula:C24H25ClN2O2·HClPurity:99.38% - 99.67%Color and Shape:White SolidMolecular weight:445.38TNCA
CAS:TNCA (Lycoperodine-1) is a high-affinity CaSR ligand (CaSRL) with co-agonist activity.Formula:C12H12N2O2Purity:97.33% - 97.73%Color and Shape:SolidMolecular weight:216.2359Gadolinium chloride
CAS:Gadolinium chloride is a calcium-sensing receptor (CaSR) agonistFormula:Cl3GdPurity:98%Color and Shape:SolidMolecular weight:263.61Cinacalcet hydrochloride
CAS:Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-Formula:C22H23ClF3NPurity:99.96% - >99.99%Color and Shape:SolidMolecular weight:396.891Etelcalcetide hydrochloride
CAS:Etelcalcetide HCl, a synthetic peptide modulator of CaSR, lowers PTH in dialysis patients with secondary hyperparathyroidism.Formula:C38H73ClN20O11S2Purity:>99.99%Color and Shape:White SolidMolecular weight:1085.697NPS2390
CAS:NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)Formula:C19H21N3OPurity:97.13%Color and Shape:SolidMolecular weight:307.389Tecalcet Free Base
CAS:Tecalcet Free Base is an oral calcium receptor agonistFormula:C18H22ClNOColor and Shape:SolidMolecular weight:303.83SB-423562 HCl
CAS:SB-423562 is a calcium-sensing receptor antagonist.Formula:C26H33ClN2O4Purity:98%Color and Shape:SolidMolecular weight:473Ligustroflavone
CAS:Ligustroflavone (Nuezhenoside) has anti-inflammatory activity.Formula:C33H40O18Purity:98% - 99.92%Color and Shape:SolidMolecular weight:724.6599Poly-D-lysine hydrobromide (MW 30000-70000)
CAS:Poly-D-lysine hydrobromide (MW 30000-70000) (Poly-D-lysine HBr) is a peptide CaSR agonist that removes proteinase K-resistant PrP from SN56 neuroblastoma cells.Formula:(C6H14N2O2)x·xHBrColor and Shape:Yellow ViscousMolecular weight:227.102NPS-2143
CAS:NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.Formula:C24H25ClN2O2Purity:99.56%Color and Shape:SolidMolecular weight:408.921Calhex 231 hydrochloride
CAS:Calhex 231 hydrochloride a potent CaSR negative-conversion modulator that blocks the increase in [3H]inositol phosphate, inhibits mir-208a-mediated .Formula:C25H28Cl2N2OPurity:99.36%Color and Shape:SolidMolecular weight:443.41
