Opioid Receptor
Opioid receptors are a group of G protein-coupled receptors that mediate the effects of endogenous and exogenous opioids. These receptors play a central role in pain modulation, mood regulation, and addictive behaviors. Opioid receptor agonists and antagonists are extensively used in pain management and addiction treatment, as well as in research on neurological and psychiatric disorders. At CymitQuimica, we provide a comprehensive selection of high-quality opioid receptor modulators to support your research in neurobiology, pain management, and addiction therapy.
Found 330 products for "Opioid Receptor".
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Trimebutine maleate
CAS:Trimebutine maleate (Polibutin) is a weak mu-opioid agonist and has antimuscarinic effects.Formula:C26H33NO9Purity:99.89% - 99.98%Color and Shape:White SolidMolecular weight:503.55LY2940094
CAS:LY2940094 (LY-2940094) decreases ethanol self-administration in animal models.Formula:C22H23ClF2N4O2SPurity:99.4%Color and Shape:White SolidMolecular weight:480.96Ref: TM-T15799
1mg77.00€2mg101.00€5mg155.00€1mL*10mM (DMSO)170.00€10mg259.00€25mg513.00€50mg737.00€100mg1,018.00€CP 866087
CAS:CP 866087 is an opioid receptor antagonist for the study of female sexual dysfunction.Formula:C24H30N2O3SPurity:99.22% - 99.74%Color and Shape:SolidMolecular weight:426.57Samidorphan HCl
CAS:Samidorphan HCl is an orally active and highly potent modulator of the opioid system that binds to μ‐opioid, κ‐opioid, and delta-opioid receptors.Formula:C21H27ClN2O4Purity:96.79% - 97.85%Color and Shape:SolidMolecular weight:406.9Alvimopan
CAS:Alvimopan is a potent opioid antagonist targeting gut receptors to reverse opioid effects on motility.Formula:C25H32N2O4Purity:99.47% - 99.78%Color and Shape:SolidMolecular weight:424.53Ref: TM-T1242
1mg44.00€2mg57.00€5mg93.00€1mL*10mM (DMSO)94.00€10mg120.00€25mg220.00€50mg356.00€100mg530.00€200mg755.00€Matrine
CAS:Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.Formula:C15H24N2OPurity:99.77% - >99.99%Color and Shape:White SolidMolecular weight:248.36Apitegromab
CAS:Apitegromab (SRK-015) is a new myostatin inhibitor, an antibody targeting myostatin precursor, which can be used to study neuromuscular diseases includingPurity:97.59% (SDS-PAGE); 99.78% (SEC-HPLC) - >95.0% (SDS-PAGE); 99.62% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.06 kDaLoperamide hydrochloride
CAS:Loperamide hydrochloride (ADL 2-1294) is a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity.Formula:C29H34Cl2N2O2Purity:99.91% - >99.99%Color and Shape:White SolidMolecular weight:513.50SNC 80
CAS:SNC 80, a non-peptide δ-opioid agonist (Ki=1.78 nM, IC50=2.73 nM), also targets μ-δ heteromers (EC50=52.8 nM), with analgesic and antidepressant potential.Formula:C28H39N3O2Purity:99.65%Color and Shape:SolidMolecular weight:449.63Moguisteine
CAS:Moguisteine (BBR-2173) is a new-type peripheral non-narcotic antitussive drug.Formula:C16H21NO5SPurity:99.98%Color and Shape:White SolidMolecular weight:339.41Sinomenine hydrochloride
CAS:Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.Formula:C19H24ClNO4Purity:99.43%Color and Shape:White SolidMolecular weight:365.85ZT 52656A hydrochloride
CAS:ZT 52656A is a selective agonist of kappa opioid, and used for the prevention or alleviation of pain in the eye.Formula:C19H26ClF3N2OPurity:98.78%Color and Shape:SolidMolecular weight:390.87Ref: TM-T13414
1mg94.00€5mg222.00€1mL*10mM (DMSO)245.00€10mg356.00€25mg715.00€50mg1,144.00€100mg1,783.00€Meptazinol hydrochloride
CAS:Meptazinol hydrochloride (Meptazinol HCl) , a unique centrally opioid analgesic, is used as a narcotic antagonist with analgesic properties.Formula:C15H23NO·HClPurity:99.75%Color and Shape:SolidMolecular weight:269.81Naltrexone hydrochloride
CAS:Naltrexone hydrochloride (Naltrexone HCl) is a synthetic opioid antagonist used in the prevention of relapse of opiate addiction and alcoholism.Formula:C20H24ClNO4Purity:98.72% - 99.65%Color and Shape:SolidMolecular weight:377.862BTRX-335140
CAS:BTRX-335140 (CYM-53093) is a potent and selective orally active κ-opioid receptor (KOR) antagonist with antagonistic activity.Cost-effective and quality-assured.Formula:C25H32FN5O2Purity:98% - 99.89%Color and Shape:White SolidMolecular weight:453.55Ref: TM-T14835
1mg100.00€2mg146.00€5mg236.00€1mL*10mM (DMSO)268.00€10mg385.00€25mg797.00€50mg1,305.00€100mg1,783.00€200mg2,493.00€CTAP
CAS:Potent μ opioid antagonist, IC50 3.5 nM, 1200x selectivity over δ and somatostatin, brain-penetrant, active in vivo.Formula:C51H69N13O11S2Purity:98%Color and Shape:SolidMolecular weight:1104.32β-Naltrexamine dihydrochloride
CAS:β-Naltrexamine dihydrochloride is an orally administered, irreversible opioid receptor antagonist. Its derivatives exhibit optimised subtype selectivity and can be used for pain research.Formula:C20H28Cl2N2O3Purity:95.98%Color and Shape:SolidMolecular weight:415.35Cebranopadol hemicitrate
CAS:Cebranopadol hemicitrate is a NOP and opioid receptor agonist that targets human NOP, MOP, KOP, and δ-opioid peptide (DOP) receptors, with Ki/EC50 values of 0.9 nM/13 nM, 0.7 nM/1.2 nM, 2.6 nM/17 nM, and 18 nM/110 nM, respectively. It is used in studies of acute and chronic pain.Color and Shape:Solid[Des-Tyr1]-γ-Endorphin
CAS:[Des-Tyr1]-gamma-Endorphin is a neuropeptide found in human cerebrospinal fluid. It exhibits antidepressant activity, helps eliminate active avoidance behaviors in rats, and reduces passive avoidance behaviors in these animals.Formula:C74H122N18O25SColor and Shape:SolidMolecular weight:1695.93KOR agonist 5
KOR agonist 5 (Compound 10a) is both a KOR/MOR modulator, exhibiting agonistic effects on KOR and antagonistic effects on MOR. It effectively blocks morphine-induced antinociception and gastrointestinal motility inhibition. KOR agonist 5 is applicable in research related to substance use disorder (SUD).Formula:C38H38N2O5Color and Shape:SolidMolecular weight:602.72KOR agonist 4
KOR agonist 4 (compound 39) is an agonist targeting the κ opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTPγS. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the κ opioid receptor over the μ (MOR) and δ (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.Formula:C21H25N3Color and Shape:SolidMolecular weight:319.44MT-7716 free base
CAS:MT-7716: selective NOP agonist, potential in preventing alcohol abuse/relapse.Formula:C27H28N4O2Purity:98%Color and Shape:SolidMolecular weight:440.54μ/κ/δ opioid receptor agonist 1
μ/κ/δopioid receptor agonist1 is an agonist for the μ opioid receptor (MOR), κ opioid receptor (KOR), and δ opioid receptor (DOR). It produces potent and long-lasting analgesic effects in the tail flick test through peripheral MOR and KOR activation.Formula:C35H45FN8O8Color and Shape:SolidMolecular weight:724.33444Axelopran
CAS:Axelopran (TD-1211) treats opioid constipation; it's a potent, selective peripheral opioid blocker.Formula:C26H39N3O4Color and Shape:SolidMolecular weight:457.61Herkinorin
CAS:Herkinorin: μ-opioid agonist with 100x μ-affinity, 50x less κ-affinity than Salvinorin A, from Salvia divinorum. Semi-synthetic from Salvinorin B.Formula:C28H30O8Color and Shape:SolidMolecular weight:494.53Kentsin
CAS:Kentsin, as a contraceptive polypeptide, has central opiate properties on gastrointestinal motility.Formula:C21H40N8O6Color and Shape:SolidMolecular weight:500.59Dermorphin Analog
Dermorphin Analog, a heptapeptide from amphibian skin, binds μ-opioid receptors selectively and strongly.Formula:C44H59N11O10Purity:98%Color and Shape:SolidMolecular weight:901.43[(pF)Phe4]Nociceptin(1-13)NH2
CAS:Potent, selective OP4 agonist; pKi=10.68, pEC50=9.80. >8000x selectivity vs other opioid receptors; long-lasting in vivo effects.Formula:C61H99FN22O15Purity:98%Color and Shape:SolidMolecular weight:1399.6[DPro10] Dynorphin A (1-11)acetate,porcine
[DPro10] Dynorphin A (1-11)acetate,porcine is a highly potent κ-opioid receptor agonist with a Ki value of 0.13 nM.Formula:C65H107N21O15Purity:99.59%Color and Shape:SolidMolecular weight:1422.7DAMGO (TFA)
CAS:DAMGO is a selective peptide agonist of the µ-opioid receptor .Formula:C28H36F3N5O8Purity:98%Color and Shape:SolidMolecular weight:627.61Gluten Exorphin B5
CAS:Gluten exorphin B5 (GE-B5) is a food-derived opioid peptide identified in digests of wheat gluten.Formula:C30H38N6O7Purity:98%Color and Shape:SolidMolecular weight:594.66Dynorphin B (1-13)
CAS:Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.Formula:C74H115N21O17Purity:98%Color and Shape:SolidMolecular weight:1570.84Orphanin FQ(1-11)
CAS:Nociceptin peptide fragment (1-11) with potent ORL1/KOR-3 receptor agonism (Ki = 55 nM), no opioid receptor affinity, and analgesic in mice.Formula:C49H75N15O14Purity:98%Color and Shape:SolidMolecular weight:1098.2Akuammicine
CAS:Akuammicine, as an indole alkaloid from Catharanthus roseus, can be used in cancer cell eradication.Formula:C20H22N2O2Color and Shape:SolidMolecular weight:322.408[Nphe1]Nociceptin(1-13)NH2
CAS:Competitive nociceptin receptor antagonist with pKi=8.4; no agonist activity; blocks nociceptin effects in vitro/in vivo.Formula:C61H100N22O15Purity:98%Color and Shape:SolidMolecular weight:1381.6Neuropeptide AF (human)
CAS:Neuropeptide AF (93-110), Human is an endogenous antiopioid peptide.Formula:C90H132N26O25Purity:98%Color and Shape:SolidMolecular weight:1978.17Frakefamide TFA
Frakefamide TFA: potent, peripherally active μ-opioid agonist; doesn't cross blood-brain barrier.Formula:C32H35F4N5O7Color and Shape:SolidMolecular weight:677.64β-Endorphin, equine TFA
β-Endorphin, equine TFA, an endogenous opioid peptide, demonstrates high affinity binding to μ/δ opioid receptors and possesses analgesic properties [1] [2] [3Formula:C156H249F3N42O46SColor and Shape:SolidMolecular weight:3537.96DPDPE
CAS:DPDPE is selective δ-opioid receptor agonist peptide.Formula:C30H39N5O7S2Purity:98%Color and Shape:SolidMolecular weight:645.79HINT1-IN-1
HINT1-IN-1 (compound 8) is an inhibitor of histidine triad nucleotide-binding protein 1 (HINT1) with a Ki of 1.14 μM. It influences the cross-regulation between μ-opioid receptors (MOR) and NMDA receptors (NMDAR).Formula:C23H24N8O5Color and Shape:SolidMolecular weight:492.49NP-5497-KA
NP-5497-KA is a κ-opioid receptor agonist with oral bioavailability.Formula:C26H39Cl3N4O2Color and Shape:SolidMolecular weight:544.21386Ac-RYYRIK-NH2
CAS:NOP site high affinity ligand (Ki=1.5 nM); blocks nociceptin effects in rat brain/heart; agonist in vivo, reduces mouse movement.Formula:C44H70N14O9Purity:98%Color and Shape:SolidMolecular weight:939.12δ opioid receptor antagonist 1
Compound 6-Cy3, a δ-opioid receptor antagonist, serves as a highly selective fluorescent probe for δ-opioid receptors (DOR), showcasing an affinity (Ki=1.7 nM). This compound is used in the study of pain perception mechanisms.Color and Shape:Odour SolidU-54494A hydrochloride
CAS:U-54494A hydrochloride is a benzamide derivative related to kappa opioid receptor agonists. U-54494A hydrochloride has anticonvulsant activity.Formula:C18H25Cl3N2OColor and Shape:SolidMolecular weight:391.76ICI 174,864
CAS:Selective δ opioid antagonist. Exhibits partial agonist in vitro activity at δ receptors at high concentrations.Formula:C38H53N5O7Purity:98%Color and Shape:White SolidMolecular weight:691.87UFP-101
CAS:Strong, selective NOP receptor antagonist with pKi=10.24; >3000x selectivity over δ, μ, κ receptors; blocks nociceptin effects.Formula:C82H138N32O21Purity:98%Color and Shape:SolidMolecular weight:1908.19Dermorphin
CAS:Dermorphin is agonist of μ-opioid receptor (MOR) agonist.Formula:C40H50N8O10Purity:98.82%Color and Shape:White SolidMolecular weight:802.87KOR agonist 6
KOR agonist 6 is a KOR agonist with a Ki value of 0.25 pM. In CHO cells, it exhibits agonistic activity on MOR and DOR and inhibits forskolin-stimulated cAMP accumulation. The compound stimulates KOR-mediated [35S]GTPγS binding in HEK293 cells expressing KOR and effectively suppresses cAMP accumulation as a potent agonist, showing lower β-arrestin recruitment efficacy. Additionally, KOR agonist 6 demonstrates analgesic effects in mice and can be employed in the study of analgesics with reduced central nervous system (CNS) side effects.Color and Shape:Odour SolidNociceptin(1-7)
CAS:Bioactive metabolite of nociceptin, antagonist of nociceptin-induced hyperalgesiaFormula:C31H41N7O9Purity:98%Color and Shape:SolidMolecular weight:655.709PL-017
CAS:μ opioid receptor agonist; IC50: 5.5 nM (μ), >10,000 nM (δ). Induces reversible analgesia, catalepsy, hyperthermia in rats.Formula:C29H37N5O5Purity:98%Color and Shape:SolidMolecular weight:535.64
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