PKA
Protein kinase A (PKA) is a key enzyme in the GPCR signaling cascade, activated by cyclic AMP (cAMP) in response to various extracellular signals. PKA regulates a wide range of cellular processes, including metabolism, gene expression, and cell growth. Dysregulation of PKA activity is associated with various diseases, including cancer, metabolic disorders, and cardiovascular conditions. PKA modulators are valuable tools in research aimed at understanding GPCR signaling pathways and developing new therapeutic strategies. At CymitQuimica, we provide a selection of high-quality PKA modulators to support your research in signal transduction, cellular regulation, and disease mechanisms.
Found 58 products for "PKA".
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MR-L2
CAS:MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).Formula:C19H16Cl3FN4OPurity:98.09% - 98.94%Color and Shape:SolidMolecular weight:441.714Ref: TM-T12103
1mg138.00€2mg196.00€5mg334.00€1mL*10mM (DMSO)357.00€10mg500.00€25mg806.00€50mg1,098.00€100mg1,485.00€500mg2,961.00€A-3 hydrochloride
CAS:A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.Formula:C12H14Cl2N2O2SPurity:99.32%Color and Shape:SolidMolecular weight:321.22Bucladesine sodium
CAS:Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties.Formula:C18H23N5NaO8PPurity:96.56% - 99.76%Color and Shape:White SolidMolecular weight:491.37PKI (5-24),amide
CAS:PKI (5-24),amide is a 20-residue peptide, a potent PKA inhibitor with a Ki of 2.3 nM, derived from a cAMP inhibitor protein.Formula:C94H149N33O30Color and Shape:SolidMolecular weight:2221.4Fasudil
CAS:Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Formula:C14H17N3O2SPurity:99.84% - 99.97%Color and Shape:White SolidMolecular weight:291.369BPDEtide
CAS:BPDEtide is a synthetic peptide with apparent Km values for cGK and cAK of 68 and 320 μM, respectively. It is the most selective peptide substrate used to measure cGK activity.Formula:C68H115N23O20Color and Shape:SolidMolecular weight:1574.78Malantide TFA
Malantide TFA: synthetic dodecapeptide, PKA-specific with Km 15 μM, >90% PKI blockage, also PKC substrate, Km 16 μM.Formula:C74H125F3N22O23Color and Shape:SolidMolecular weight:1747.91JAK1/2/3 Inhibitor 1
CAS:JAK1/2/3 Inhibitor 1 is a potent protein kinase inhibitor.JAK1/2/3 Inhibitor 1 has antitumor activity that inhibits the growth of a variety of cancer cell linesFormula:C6H2Cl2N2SPurity:99.32%Color and Shape:SolidMolecular weight:205.064CREBtide
CAS:CREBtide is a synthetic substrate for PKA (Km=3.9 µM), which is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein).Formula:C73H129N29O19Purity:98%Color and Shape:SolidMolecular weight:1716.99PKG inhibitor peptide
CAS:PKG inhibitor; mimics H2B phosphorylation site; Ki=86mM; blocks synthetic substrates, not histone phosphorylation; stops PKA activity on histones.Formula:C38H74N18O10Purity:98%Color and Shape:SolidMolecular weight:943.12DT-2 acetate
DT-2 acetate, a selective cGMP-dependent protein kinase (PKG) inhibitor, is a mouse monoclonal antibody targeting canine thymocytes.DT-2 acetate inhibits PKG-catalyzed phosphorylation, reverses 8-Br-cGMP-induced expansion, and can be used to study immune disorders.Formula:C154H287N53O55Purity:99.80%Color and Shape:SolidMolecular weight:3761.25PKI(5-24)
CAS:High affinity PKA inhibitor (Ki = 2.3 nM).Formula:C94H148N32O31Purity:98%Color and Shape:SolidMolecular weight:2222.3767Gliotoxin
CAS:Gliotoxin, a mycotoxin, inhibits Wnt pathway, causing apoptosis in mutated colorectal cancer cells and blocks NF-κB by preserving IκB.Formula:C13H14N2O4S2Purity:98%Color and Shape:SolidMolecular weight:326.39Vasonatrin Peptide (VNP)
CAS:Vasonatrin peptide (VNP) is a chimera of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP) with potent venodilating and natriuretic activityFormula:C123H198N36O36S3Purity:98%Color and Shape:SolidMolecular weight:2865.37Kemptide Phospho-Ser5
Kemptide (Phospho-Ser5) is a phosphoreceptor peptide that is a specific substrate for camp-dependent protein kinase (PKA).Formula:C32H62N13O12PPurity:98%Color and Shape:SolidMolecular weight:851.89PKG Substrate
CAS:PKG Substrate is selective for PKG, favors PKG Iα (Km=59µM) over PKG II (Km=305µM).Formula:C35H67N17O11Purity:98%Color and Shape:SolidMolecular weight:902.0138Malantide
CAS:Malantide, a synthetic dodecapeptide, boosts and measures PKA activity by undergoing PKA-induced phosphorylation.Formula:C72H124N22O21Purity:98%Color and Shape:SolidMolecular weight:1633.89Calcineurin substrate
CAS:Calcineurin Substrate is a Peptide from the regulatory RII subunit of cAMP-dependent protein kinase.Formula:C92H150N28O29Purity:98%Color and Shape:SolidMolecular weight:2112.3457H1-7 (histone H1 phosphorylation site), PKA Substrate
CAS:H1-7 (histone H1 phosphorylation site), a synthetic polypeptide serving as a PKA substrate, demonstrates utility in PKA substrate applications [1] [2].Formula:C31H58N14O9Color and Shape:SolidMolecular weight:770.88STAD 2
CAS:STAD-2 is a cell permeable akap disruptor, selectively binding to pka-rii and blocking the interaction of pka-ri with akapFormula:C102H182N24O22Color and Shape:SolidMolecular weight:2096.724
