PKA
Protein kinase A (PKA) is a key enzyme in the GPCR signaling cascade, activated by cyclic AMP (cAMP) in response to various extracellular signals. PKA regulates a wide range of cellular processes, including metabolism, gene expression, and cell growth. Dysregulation of PKA activity is associated with various diseases, including cancer, metabolic disorders, and cardiovascular conditions. PKA modulators are valuable tools in research aimed at understanding GPCR signaling pathways and developing new therapeutic strategies. At CymitQuimica, we provide a selection of high-quality PKA modulators to support your research in signal transduction, cellular regulation, and disease mechanisms.
Found 63 products for "PKA".
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Kemptide Phospho-Ser5
Kemptide (Phospho-Ser5) is a phosphoreceptor peptide that is a specific substrate for camp-dependent protein kinase (PKA).Formula:C32H62N13O12PPurity:98%Color and Shape:SolidMolecular weight:851.89PKG Substrate
CAS:PKG Substrate is selective for PKG, favors PKG Iα (Km=59µM) over PKG II (Km=305µM).Formula:C35H67N17O11Purity:98%Color and Shape:SolidMolecular weight:902.01AP-C2
CAS:AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.Formula:C18H16N4SPurity:99.99%Color and Shape:SoildMolecular weight:320.41Malantide TFA
Malantide TFA: synthetic dodecapeptide, PKA-specific with Km 15 μM, >90% PKI blockage, also PKC substrate, Km 16 μM.Formula:C74H125F3N22O23Color and Shape:SolidMolecular weight:1747.91H1-7 (histone H1 phosphorylation site), PKA Substrate
CAS:H1-7 (histone H1 phosphorylation site), a synthetic polypeptide serving as a PKA substrate, demonstrates utility in PKA substrate applications [1] [2].Formula:C31H58N14O9Color and Shape:SolidMolecular weight:770.88PKA-IN-1
CAS:PKA-IN-1 is a selective and potent cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor (IC50: 0.03 μM).PKA-IN-1 can be used to studyFormula:C13H11N3OPurity:99.12%Color and Shape:SolidMolecular weight:225.25PKI (5-24),amide
CAS:PKI (5-24),amide is a 20-residue peptide, a potent PKA inhibitor with a Ki of 2.3 nM, derived from a cAMP inhibitor protein.Formula:C94H149N33O30Color and Shape:SolidMolecular weight:2221.4PKItide
CAS:PKItide demonstrates an inhibitory concentration 50 (IC50) of 0.2 μM against cAMP-dependent protein kinase (cAMP-PK) [1].Formula:C85H149N31O24Purity:98%Color and Shape:SolidMolecular weight:1989.29STAD 2
CAS:STAD-2 is a cell permeable akap disruptor, selectively binding to pka-rii and blocking the interaction of pka-ri with akapFormula:C102H182N24O22Color and Shape:SolidMolecular weight:2096.724Fasudil
CAS:Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Formula:C14H17N3O2SPurity:99.79% - 99.97%Color and Shape:SolidMolecular weight:291.37DT-3 acetate
DT-3 acetate is a cell-permeable peptide that acts as an inhibitor of protein kinase G (PKGIα), effectively blocking the cGMP-PKG signaling pathway.Formula:C152H258N52O28S·xC2H4O2Color and Shape:SolidMolecular weight:3294.07 (free acid)AT13148
CAS:AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.Formula:C17H16ClN3OPurity:98.04% - ≥95%Color and Shape:SolidMolecular weight:313.78HA-100
CAS:HA-100 is an inhibitor of protein kinaseFormula:C13H15N3O2SPurity:99.44%Color and Shape:Pale Yellow Crystalline SolidMolecular weight:277.34Staurosporine
CAS:Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-FgrFormula:C28H26N4O3Purity:99.24% - 99.82%Color and Shape:Off-White PowderMolecular weight:466.53Ref: TM-T6680
1mg58.00€2mg82.00€5mg92.00€1mL*10mM (DMSO)103.00€10mg138.00€25mg234.00€50mg380.00€100mg565.00€500mg1,215.00€8-Bromo-cAMP sodium salt
CAS:8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. 8-Bromo-cAMP is an activator of cyclic AMP-dependent protein kinase.Formula:C10H10BrN5NaO6PPurity:98% - 99.94%Color and Shape:Off-White PowderMolecular weight:430.08Iso-H7 dihydrochloride
CAS:Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.Formula:C14H19Cl2N3O2SPurity:99.53%Color and Shape:White Crystalline SolidMolecular weight:364.29CCG215022
CAS:CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, 5 and 1, respectively.Formula:C26H22FN7O3Purity:97.63% - 99.69%Color and Shape:SolidMolecular weight:499.5Ref: TM-T3498
1mg56.00€5mg114.00€1mL*10mM (DMSO)127.00€10mg178.00€25mg394.00€50mg655.00€100mg1,035.00€AT7867
CAS:AT7867 inhibits Akt1/2/3 & p70S6K/PKA (IC50: 32/17/47 nM & 85/20 nM), minimal effect beyond AGC kinases.Formula:C20H20ClN3Purity:99.63%Color and Shape:SolidMolecular weight:337.85Ref: TM-T6304
2mg42.00€5mg62.00€1mL*10mM (DMSO)62.00€10mg81.00€25mg128.00€50mg198.00€100mg296.00€200mg427.00€Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formula:C9H6O4Purity:97.47% - 99.95%Color and Shape:SolidMolecular weight:178.14Bilobetin
CAS:Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.Formula:C31H20O10Purity:97% - 99.69%Color and Shape:SolidMolecular weight:552.48Ref: TM-T4S2128
1mg44.00€2mg66.00€5mg137.00€1mL*10mM (DMSO)177.00€10mg236.00€25mg403.00€50mg582.00€100mg800.00€
