GPCR19
GPCR19, also known as GPR19, is a member of the G protein-coupled receptor family with roles that are still being elucidated in various physiological processes. Although less characterized than other GPCRs, GPCR19 is of interest in research focused on discovering new therapeutic targets for metabolic diseases, cancer, and neurological disorders. At CymitQuimica, we offer a selection of research tools and reagents to support your investigations into the functions and potential therapeutic applications of GPCR19.
Found 33 products of "GPCR19"
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Hyodeoxycholic acid
CAS:Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia.Formula:C24H40O4Purity:97.29% - 98.82%Color and Shape:SolidMolecular weight:392.57Deoxycholic acid
CAS:Deoxycholic acid (Cholanoic Acid) is a bile acid formed by bacterial action from cholate.Formula:C24H40O4Purity:99.91% - 99.91%Color and Shape:Crystals From Alc SolidMolecular weight:392.57Ursodeoxycholic acid
CAS:Ursodeoxycholic acid (UDCA) is a potent inhibitor of liver-specific fatty acid transporter 5 (FATP5),inhibits cholesterol absorption. High-Quality, Low-Cost!Formula:C24H40O4Purity:99.74% - ≥95%Color and Shape:White - Almost White Solid PowderMolecular weight:392.57Cholic Acid 7-sulfate
CAS:Cholic acid 7-sulfate: a cholic acid metabolite with added sulfate at position 7, increased in feces of male mice with specific diets.Formula:C24H40O8SColor and Shape:SolidMolecular weight:488.64TGR5 agonist 1
Compound 18 (TGR5 agonist 1) is a potent agonist of TGR5, exhibiting an EC50 value of 0.31 µM [1].Formula:C28H48NNaO6SColor and Shape:SolidMolecular weight:549.74TGR5 agonist 4
TGR5 agonist 4 (compound 19), a derivative of cholic acid, selectively activates the TGR5 receptor with an effective concentration (EC50) of 4 μM [1].Formula:C24H38F2O5Color and Shape:SolidMolecular weight:444.555-HT7R antagonist 1 free base
CAS:5-HT7R antagonist 1 (free base) is a G protein-biased antagonist for the 5-HT 7 R receptor, with a dissociation constant (K i) of 6.5 nM.Formula:C14H17ClN4Color and Shape:SolidMolecular weight:276.77PEN (human)
CAS:PEN (human) is an Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.Formula:C97H159N27O32Purity:98%Color and Shape:SolidMolecular weight:2215.49PEN (rat)
CAS:PEN (rat) is an Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.Formula:C102H169N27O33Purity:98%Color and Shape:SolidMolecular weight:2301.62TGR5 agonist 2
TGR5 agonist 2 (compound 19) serves as a highly potent agonist of TGR5, demonstrating an EC50 value of 0.27 µM [1].Formula:C29H50NNaO6SColor and Shape:SolidMolecular weight:563.77TGR5 agonist 6
CAS:Compound 22b, also known as TGR5 agonist 6, is a non-systemic, intestine-targeted TGR5 agonist that demonstrates significant and sustained blood glucose-lowering effects with an acceptable safety profile.Formula:C42H48Cl2N6O6Color and Shape:SolidMolecular weight:803.77TGR5 agonist 7
TGR5 agonist 7 (Compound 22-Na) is an intestine-restricted, orally active agonist of the G protein-coupled bile acid receptor TGR5 (GPBAR1 or GPR131) with an EC50 of less than 1 μM. In mouse models, it demonstrates blood glucose-lowering effects, making it useful for diabetes research.Formula:C37H59N2NaO9SColor and Shape:SolidMolecular weight:730.93Neuromedin S (human)
CAS:Neuromedin S (human) is a 33-amino acid neuropeptide identified as an endogenous ligand for the orphan G-protein coupled receptor (GPCR) FM-4/TGR-1, acting onColor and Shape:SolidTriamterene
CAS:Triamterene is a barosensitive epithelial sodium channel (ENaC) blocker with a diuretic effect. It can also act as an inhibitor of the TGR5 receptor, reducing GLP-1 secretion and cAMP level increases induced by TGR5 activation in a dose-dependent manner.Formula:C12H11N7Purity:99.77%Color and Shape:Yellow Yellow SolidMolecular weight:253.26Deoxycholic acid sodium salt
CAS:Deoxycholic acid sodium salt (Sodium deoxycholate) can activate the G protein-coupled bile acid receptor TGR5 that stimulates BAT thermogenic activity.Formula:C24H39NaO4Purity:97.88% - 99.84%Color and Shape:Cream Crystalline PowderMolecular weight:414.56TC-G 1005
CAS:TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5).Formula:C25H25N3O2Purity:98.60% - 99.78%Color and Shape:SolidMolecular weight:399.48Ref: TM-T8818
1mg34.00€2mg43.00€5mg65.00€10mg90.00€25mg178.00€50mg269.00€100mg400.00€1mL*10mM (DMSO)72.00€SBI-115
CAS:SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5Formula:C14H13ClN2O4SPurity:99.53% - 99.78%Color and Shape:SolidMolecular weight:340.78SB756050
CAS:SB756050 is a specific TGR5 agonist.Formula:C21H28N2O8S2Purity:98.78% - >99.99%Color and Shape:SolidMolecular weight:500.59BAR502
CAS:BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).Formula:C25H44O3Purity:99.95%Color and Shape:SolidMolecular weight:392.62TGR5 Receptor Agonist
CAS:TGR5 is a potent TGR5(GPCR19) agonist.Formula:C18H14Cl2N2O2Purity:99.77% - ≥95%Color and Shape:SolidMolecular weight:361.22
