GPCR19
GPCR19, also known as GPR19, is a member of the G protein-coupled receptor family with roles that are still being elucidated in various physiological processes. Although less characterized than other GPCRs, GPCR19 is of interest in research focused on discovering new therapeutic targets for metabolic diseases, cancer, and neurological disorders. At CymitQuimica, we offer a selection of research tools and reagents to support your investigations into the functions and potential therapeutic applications of GPCR19.
Found 36 products of "GPCR19"
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Deoxycholic acid
CAS:Deoxycholic acid (Cholanoic Acid) is a bile acid formed by bacterial action from cholate.Formula:C24H40O4Purity:99.91% - 99.91%Color and Shape:Crystals From Alc SolidMolecular weight:392.57Ursodeoxycholic acid
CAS:Ursodeoxycholic acid (UDCA) is a potent inhibitor of liver-specific fatty acid transporter 5 (FATP5),inhibits cholesterol absorption. High-Quality, Low-Cost!Formula:C24H40O4Purity:99.74% - ≥95%Color and Shape:White - Almost White Solid PowderMolecular weight:392.57Hyodeoxycholic acid
CAS:Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia.Formula:C24H40O4Purity:97.29% - 98.82%Color and Shape:SolidMolecular weight:392.57TGR5 agonist 2
TGR5 agonist 2 (compound 19) serves as a highly potent agonist of TGR5, demonstrating an EC50 value of 0.27 µM [1].Formula:C29H50NNaO6SColor and Shape:SolidMolecular weight:563.77TGR5 agonist 6
CAS:Compound 22b, also known as TGR5 agonist 6, is a non-systemic, intestine-targeted TGR5 agonist that demonstrates significant and sustained blood glucose-lowering effects with an acceptable safety profile.Formula:C42H48Cl2N6O6Color and Shape:SolidMolecular weight:803.77TGR5 agonist 1
Compound 18 (TGR5 agonist 1) is a potent agonist of TGR5, exhibiting an EC50 value of 0.31 µM [1].Formula:C28H48NNaO6SColor and Shape:SolidMolecular weight:549.74TGR5 agonist 4
TGR5 agonist 4 (compound 19), a derivative of cholic acid, selectively activates the TGR5 receptor with an effective concentration (EC50) of 4 μM [1].Formula:C24H38F2O5Color and Shape:SolidMolecular weight:444.55PEN (human)
CAS:PEN (human) is an Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.Formula:C97H159N27O32Purity:98%Color and Shape:SolidMolecular weight:2215.49Cholic Acid 7-sulfate
CAS:Cholic acid 7-sulfate: a cholic acid metabolite with added sulfate at position 7, increased in feces of male mice with specific diets.Formula:C24H40O8SColor and Shape:SolidMolecular weight:488.64TGR5 agonist 7
TGR5 agonist 7 (Compound 22-Na) is an intestine-restricted, orally active agonist of the G protein-coupled bile acid receptor TGR5 (GPBAR1 or GPR131) with an EC50 of less than 1 μM. In mouse models, it demonstrates blood glucose-lowering effects, making it useful for diabetes research.Formula:C37H59N2NaO9SColor and Shape:SolidMolecular weight:730.93PEN (rat)
CAS:PEN (rat) is an Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.Formula:C102H169N27O33Purity:98%Color and Shape:SolidMolecular weight:2301.625-HT7R antagonist 1 free base
CAS:5-HT7R antagonist 1 (free base) is a G protein-biased antagonist for the 5-HT 7 R receptor, with a dissociation constant (K i) of 6.5 nM.Formula:C14H17ClN4Color and Shape:SolidMolecular weight:276.77Triamterene
CAS:Triamterene is a barosensitive epithelial sodium channel (ENaC) blocker with a diuretic effect. It can also act as an inhibitor of the TGR5 receptor, reducing GLP-1 secretion and cAMP level increases induced by TGR5 activation in a dose-dependent manner.Formula:C12H11N7Purity:99.77%Color and Shape:Yellow Yellow SolidMolecular weight:253.26Neuromedin S (human)
CAS:Neuromedin S (human) is a 33-amino acid neuropeptide identified as an endogenous ligand for the orphan G-protein coupled receptor (GPCR) FM-4/TGR-1, acting onColor and Shape:SolidTriamterene (Standard)
CAS:Triamterene (Standard) is the standard substance of Triamterene, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Triamterene is a barosensitive epithelial sodium channel (ENaC) blocker with a diuretic effect. It can also act as an inhibitor of the TGR5 receptor, reducing GLP-1 secretion and cAMP level increases induced by TGR5 activation in a dose-dependent manner.Formula:C12H11N7Color and Shape:Yellow Yellow SolidMolecular weight:253.26TC-G 1005
CAS:TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5).Formula:C25H25N3O2Purity:98.60% - 99.78%Color and Shape:SolidMolecular weight:399.48Ref: TM-T8818
1mg34.00€2mg43.00€5mg65.00€1mL*10mM (DMSO)72.00€10mg90.00€25mg178.00€50mg269.00€100mg400.00€SB756050
CAS:SB756050 is a specific TGR5 agonist.Formula:C21H28N2O8S2Purity:98.78% - >99.99%Color and Shape:SolidMolecular weight:500.59Ursodeoxycholic acid sodium
CAS:Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities.Formula:C24H40NaO4Purity:99.66% - 99.96%Color and Shape:SolidMolecular weight:415.56BAR502
CAS:BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).Formula:C25H44O3Purity:99.95%Color and Shape:SolidMolecular weight:392.62TGR5 Receptor Agonist
CAS:TGR5 is a potent TGR5(GPCR19) agonist.Formula:C18H14Cl2N2O2Purity:99.77% - ≥95%Color and Shape:SolidMolecular weight:361.22
