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GPCR19

GPCR19

GPCR19, also known as GPR19, is a member of the G protein-coupled receptor family with roles that are still being elucidated in various physiological processes. Although less characterized than other GPCRs, GPCR19 is of interest in research focused on discovering new therapeutic targets for metabolic diseases, cancer, and neurological disorders. At CymitQuimica, we offer a selection of research tools and reagents to support your investigations into the functions and potential therapeutic applications of GPCR19.

Found 31 products of "GPCR19"

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  • Hyodeoxycholic acid
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    Hyodeoxycholic acid

    CAS:
    <p>Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia.</p>
    Formula:C24H40O4
    Purity:97.29% - 98.82%
    Color and Shape:Solid
    Molecular weight:392.57

    Ref: TM-T2968

  • Deoxycholic acid
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    Deoxycholic acid

    CAS:
    <p>Deoxycholic acid (Cholanoic Acid) is a bile acid formed by bacterial action from cholate.</p>
    Formula:C24H40O4
    Purity:99.91% - 99.91%
    Color and Shape:Crystals From Alc Solid
    Molecular weight:392.57

    Ref: TM-T2965

  • Ursodeoxycholic acid
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    Ursodeoxycholic acid

    CAS:
    <p>Ursodeoxycholic acid (UDCA) is a potent inhibitor of liver-specific fatty acid transporter 5 (FATP5),inhibits cholesterol absorption. High-Quality, Low-Cost!</p>
    Formula:C24H40O4
    Purity:99.74% - ≥95%
    Color and Shape:White - Almost White Solid Powder
    Molecular weight:392.57

    Ref: TM-T0700

  • PEN (rat)
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    PEN (rat)

    CAS:
    <p>PEN (rat) is an Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.</p>
    Formula:C102H169N27O33
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2301.62

    Ref: TM-TP1951

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    TGR5 agonist 1

    <p>Compound 18 (TGR5 agonist 1) is a potent agonist of TGR5, exhibiting an EC50 value of 0.31 µM [1].</p>
    Formula:C28H48NNaO6S
    Color and Shape:Solid
    Molecular weight:549.74

    Ref: TM-T74824

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    TGR5 agonist 4

    <p>TGR5 agonist 4 (compound 19), a derivative of cholic acid, selectively activates the TGR5 receptor with an effective concentration (EC50) of 4 μM [1].</p>
    Formula:C24H38F2O5
    Color and Shape:Solid
    Molecular weight:444.55

    Ref: TM-T79425

  • 5-HT7R antagonist 1 free base
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    5-HT7R antagonist 1 free base

    CAS:
    <p>5-HT7R antagonist 1 (free base) is a G protein-biased antagonist for the 5-HT 7 R receptor, with a dissociation constant (K i) of 6.5 nM.</p>
    Formula:C14H17ClN4
    Color and Shape:Solid
    Molecular weight:276.77

    Ref: TM-T39870

  • PEN (human)
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    PEN (human)

    CAS:
    <p>PEN (human) is an Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.</p>
    Formula:C97H159N27O32
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2215.49

    Ref: TM-TP1949

  • Cholic Acid 7-sulfate
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    Cholic Acid 7-sulfate

    CAS:
    <p>Cholic acid 7-sulfate: a cholic acid metabolite with added sulfate at position 7, increased in feces of male mice with specific diets.</p>
    Formula:C24H40O8S
    Color and Shape:Solid
    Molecular weight:488.64

    Ref: TM-T37854

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    TGR5 agonist 2

    <p>TGR5 agonist 2 (compound 19) serves as a highly potent agonist of TGR5, demonstrating an EC50 value of 0.27 µM [1].</p>
    Formula:C29H50NNaO6S
    Color and Shape:Solid
    Molecular weight:563.77

    Ref: TM-T74825

  • TGR5 agonist 6
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    TGR5 agonist 6

    CAS:
    <p>Compound 22b, also known as TGR5 agonist 6, is a non-systemic, intestine-targeted TGR5 agonist that demonstrates significant and sustained blood glucose-lowering effects with an acceptable safety profile.</p>
    Formula:C42H48Cl2N6O6
    Color and Shape:Solid
    Molecular weight:803.77

    Ref: TM-T200705

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    TGR5 agonist 7

    <p>TGR5 agonist 7 (Compound 22-Na) is an intestine-restricted, orally active agonist of the G protein-coupled bile acid receptor TGR5 (GPBAR1 or GPR131) with an EC50 of less than 1 μM. In mouse models, it demonstrates blood glucose-lowering effects, making it useful for diabetes research.</p>
    Formula:C37H59N2NaO9S
    Color and Shape:Solid
    Molecular weight:730.93

    Ref: TM-T203565

  • Triamterene
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    Triamterene

    CAS:
    <p>Triamterene is a barosensitive epithelial sodium channel (ENaC) blocker with a diuretic effect. It can also act as an inhibitor of the TGR5 receptor, reducing GLP-1 secretion and cAMP level increases induced by TGR5 activation in a dose-dependent manner.</p>
    Formula:C12H11N7
    Purity:99.77%
    Color and Shape:Yellow Yellow Solid
    Molecular weight:253.26

    Ref: TM-T0843

  • BAR502
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    BAR502

    CAS:
    <p>BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).</p>
    Formula:C25H44O3
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:392.62

    Ref: TM-TQ0252

  • BAR501
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    BAR501

    CAS:
    <p>BAR501是高效选择性的 GPBAR1激动剂(EC50:1 μM)。</p>
    Formula:C26H46O3
    Purity:99.29% - 99.68%
    Color and Shape:Solid
    Molecular weight:406.64

    Ref: TM-T4083

  • TC-G 1005
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    TC-G 1005

    CAS:
    <p>TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5).</p>
    Formula:C25H25N3O2
    Purity:98.60% - 99.78%
    Color and Shape:Solid
    Molecular weight:399.48

    Ref: TM-T8818

  • Deoxycholic acid sodium salt
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    Deoxycholic acid sodium salt

    CAS:
    <p>Deoxycholic acid sodium salt (Sodium deoxycholate) can activate the G protein-coupled bile acid receptor TGR5 that stimulates BAT thermogenic activity.</p>
    Formula:C24H39NaO4
    Purity:97.88% - 99.75%
    Color and Shape:Cream Crystalline Powder
    Molecular weight:414.56

    Ref: TM-T5077

  • SBI-115
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    SBI-115

    CAS:
    <p>SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5</p>
    Formula:C14H13ClN2O4S
    Purity:99.53% - 99.78%
    Color and Shape:Solid
    Molecular weight:340.78

    Ref: TM-T7428

  • TGR5 Receptor Agonist
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    TGR5 Receptor Agonist

    CAS:
    <p>TGR5 is a potent TGR5(GPCR19) agonist.</p>
    Formula:C18H14Cl2N2O2
    Purity:99.77% - ≥95%
    Color and Shape:Solid
    Molecular weight:361.22

    Ref: TM-T1824

  • PEN (human) aceate
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    PEN (human) aceate

    <p>PEN (human) aceate, one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83.</p>
    Formula:C99H163N27O34
    Purity:99.25%
    Color and Shape:Solid
    Molecular weight:2275.51

    Ref: TM-TP1949L