DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Found 802 products of "DNA/RNA Synthesis"
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YK-4-279
CAS:YK 4-279, an inhibitor of RNA Helicase A (RHA), binds to the oncogenic transciption factor EWS-FLI1.Formula:C17H13Cl2NO4Purity:99.80% - ≥95%Color and Shape:SolidMolecular weight:366.2EG1
CAS:EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.Formula:C22H18N2O5Purity:97.48%Color and Shape:SolidMolecular weight:390.39Ref: TM-T27246
2mg34.00€5mg54.00€10mg86.00€25mg130.00€50mg187.00€100mg260.00€200mg370.00€1mL*10mM (DMSO)33.00€Saccharin 1-methylimidazole
CAS:Saccharin 1-methylimidazole (SMI) is a general-purpose activator used for DNA and RNA synthesis.Formula:C7H5NO3S·C4H6N2Purity:98.21%Color and Shape:SolidMolecular weight:265.291,7-Diaminoheptane
CAS:1,7-Diaminoheptane, an aliphatic amine, is used in peptide synthesis and as a substrate, ligand, or reagent.Formula:C7H18N2Purity:99.97%Color and Shape:White To Light Yellow Crystalline ChunksMolecular weight:130.235-methoxyflavone
CAS:5-methoxyflavone (5-methoxy-2-phenylchromen-4-one) is a naturally occurring, low molecular weight flavonoids compound.Formula:C16H12O3Purity:99.76%Color and Shape:PowderMolecular weight:252.26Lurbinectedin
CAS:Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.Formula:C41H44N4O10SPurity:98.11%Color and Shape:SolidMolecular weight:784.87Chebulinic acid
CAS:Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.Formula:C41H32O27Purity:98.91% - 99.71%Color and Shape:SolidMolecular weight:956.68Ref: TM-TQ0184
1mg66.00€5mg145.00€10mg203.00€25mg409.00€50mg595.00€100mg833.00€1mL*10mM (DMSO)215.00€FIT-039
CAS:FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).Formula:C17H18FN3SPurity:98.61%Color and Shape:SolidMolecular weight:315.41Pyridostatin Trihydrochloride
CAS:Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.Formula:C31H35Cl3N8O5Purity:99.69%Color and Shape:SolidMolecular weight:706.02Deoxythymidine triphosphate
CAS:Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.Formula:C10H17N2O14P3·XNaPurity:99.78%Color and Shape:White Amorphous PowderMolecular weight:482.17（free base）BCH001
CAS:BCH001 is a specific small-molecule inhibitor of PAPD5.Formula:C20H15F3N2O5Purity:99.06%Color and Shape:SolidMolecular weight:420.34AG-636
CAS:AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.Formula:C21H17N3O2Purity:99.19%Color and Shape:SolidMolecular weight:343.38Dasabuvir
CAS:Dasabuvir (ABT-333) blocks HCV replication by inhibiting the essential NS5B RNA polymerase.Formula:C26H27N3O5SPurity:99.54% - 99.62%Color and Shape:SolidMolecular weight:493.57GS-441524 HCl
CAS:GS-441524: Inhibits FIP virus, EC50 at 0.78 μM, precursor to active triphosphate, non-toxic up to 100 μM, works at ≥1 μM, metabolite of Remdesivir.Formula:C12H14ClN5O4Color and Shape:SolidMolecular weight:327.72Temozolomide Acid
CAS:TMZA, a TMZ metabolite, shows in vitro anticancer effects. TMZ, an oral alkylator, treats GBM and astrocytomas.Formula:C6H5N5O3Purity:99.28%Color and Shape:SolidMolecular weight:195.14Idarubicin hydrochloride
CAS:Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).Formula:C26H27NO9·HClPurity:98.91% - 99.96%Color and Shape:SolidMolecular weight:533.95Garenoxacin mesylate hydrate
CAS:Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strainsFormula:C23H20F2N2O4·CH4O3S·H2OPurity:99.56%Color and Shape:SolidMolecular weight:540.53NSC 617145
CAS:NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependentFormula:C13H10Cl4N2O4Purity:99.78%Color and Shape:SolidMolecular weight:400.04Ref: TM-T9168
1mg34.00€2mg49.00€5mg73.00€10mg90.00€25mg164.00€50mg227.00€100mg358.00€500mg842.00€1mL*10mM (DMSO)80.00€Brr2-IN-3
CAS:Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa.Formula:C24H20N4O3SPurity:99.26%Color and Shape:SolidMolecular weight:444.51Ref: TM-T22282
1mg52.00€2mg65.00€5mg92.00€10mg161.00€25mg290.00€50mg420.00€100mg587.00€200mg792.00€1mL*10mM (DMSO)110.00€Silver sulfadiazine
CAS:Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.Formula:C10H9AgN4O2SPurity:99.04% - 99.58%Color and Shape:SolidMolecular weight:357.14POL1-IN-1
CAS:POL1-IN-1 (Compound 3A) 是一种RNA 聚合酶 1 POL1抑制剂，IC50值低于 0.5 uM。 它能有效抑制A375恶性黑色素瘤细胞系中RNA 聚合酶I 的转录。
Formula:C21H20N6Purity:98% - 98.01%Color and Shape:SolidMolecular weight:356.42Pseudouridine
CAS:Pseudouridine, prevalent in non-coding RNAs, boosts tRNA and rRNA function by RNA stabilization.Formula:C9H12N2O6Purity:99.3%Color and Shape:SolidMolecular weight:244.2Deoxycytidine triphosphate trisodium salt
CAS:Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria.Formula:C9H13N3Na3O13P3Purity:99.80%Color and Shape:SolidMolecular weight:533.1AI-10-49
CAS:AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.Formula:C30H22F6N6O5Purity:97.14%Color and Shape:SolidMolecular weight:660.52Ref: TM-T6753
2mg38.00€5mg57.00€10mg92.00€25mg160.00€50mg231.00€100mg343.00€200mg485.00€1mL*10mM (DMSO)84.00€6-Thio-2'-Deoxyguanosine
CAS:6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.Formula:C10H13N5O3SPurity:97.52%Color and Shape:SolidMolecular weight:283.31Cedazuridine hydrochloride
Cedazuridine (E7727) hydrochloride is an oral cancer research drug blocking cytidine deaminase (IC50=0.4μM).Formula:C9H15ClF2N2O5Color and Shape:SolidMolecular weight:304.68Eprociclovir potassium
CAS:Eprociclovir potassium, 15x stronger than acyclovir, inhibits EHV1 and human herpesviruses, also treats herpetic keratitis effectively with eyedrops.Formula:C11H15KN5O3Color and Shape:SolidMolecular weight:304.37HAMNO
CAS:HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).Formula:C17H13NO2Purity:99.96%Color and Shape:SolidMolecular weight:263.29Methylproamine
CAS:Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.Formula:C28H31N7Purity:99.94%Color and Shape:SolidMolecular weight:465.59N2-methylguanine
CAS:N2-methylguanine (N2-methylguanine) is an endogenous methylated nucleoside found in human fluids and a modified nucleoside.Formula:C6H7N5OPurity:99.86%Color and Shape:SolidMolecular weight:165.15Acelarin
CAS:Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.
Formula:C25H27F2N4O8PPurity:99.26%Color and Shape:SolidMolecular weight:580.47BMH-21
CAS:BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.Formula:C21H20N4O2Purity:99.47% - 99.84%Color and Shape:SolidMolecular weight:360.41Dasabuvir sodium
CAS:Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).Formula:C26H26N3NaO5SColor and Shape:SolidMolecular weight:515.56Nemorubicin HCL
CAS:Nemorubicin HCL, a PNU152243A salt, acts on resistant tumors via topoisomerase I inhibition and targets NER pathway upregulated cells.Formula:C32H38ClNO13Color and Shape:SolidMolecular weight:680.11-Hydroxyanthraquinone
CAS:1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities.Formula:C14H8O3Purity:99.56%Color and Shape:Orange Red Needles Red-Orange To Fine Yellow CrystalsMolecular weight:224.21Amenamevir
CAS:Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mLFormula:C24H26N4O5SPurity:99.00% - 99.86%Color and Shape:SolidMolecular weight:482.55Ref: TM-T4226
1mg34.00€5mg71.00€10mg92.00€25mg152.00€50mg222.00€100mg334.00€200mg494.00€1mL*10mM (DMSO)52.00€Pyridostatin hydrochloride
CAS:Pyridostatin hydrochloride stabilizes G-quadruplex DNA (Kd=490nM), inhibits cancer cell growth, and reduces SRC in breast cancer.Formula:C31H37Cl5N8O5Color and Shape:SolidMolecular weight:778.94TH5487
CAS:TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)Formula:C19H18BrIN4O2Purity:98.38% - 98.73%Color and Shape:SolidMolecular weight:541.18Ref: TM-T8119
1mg46.00€2mg59.00€5mg88.00€10mg152.00€25mg288.00€50mg520.00€100mg750.00€500mg1,521.00€1mL*10mM (DMSO)105.00€IMT1B
CAS:IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.Formula:C24H21ClFNO6Purity:98.26% - 99.83%Color and Shape:SolidMolecular weight:473.88Ref: TM-T8842
1mg138.00€5mg295.00€10mg505.00€25mg733.00€50mg888.00€100mg1,251.00€1mL*10mM (DMSO)309.00€Cidofovir dihydrate
CAS:Cidofovir dihydrate: Injectable anti-CMV; suppresses CMV by inhibiting viral DNA polymerase; treats CMV retinitis in AIDS.Formula:C8H18N3O8PPurity:99.44%Color and Shape:SolidMolecular weight:315.22TH287
CAS:TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.Formula:C11H10Cl2N4Purity:97.73% - 99%Color and Shape:SolidMolecular weight:269.13Ref: TM-T2069
1mg37.00€2mg48.00€5mg72.00€10mg96.00€25mg188.00€50mg366.00€100mg545.00€1mL*10mM (DMSO)79.00€Datelliptium chloride hydrochloride
CAS:Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.
Formula:C23H29Cl2N3OPurity:99.46%Color and Shape:SolidMolecular weight:434.4Risdiplam
CAS:Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.Formula:C22H23N7OPurity:98.68% - 99.64%Color and Shape:SolidMolecular weight:401.46Fidaxomicin
CAS:Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults.Formula:C52H74Cl2O18Purity:99.76% - 99.82%Color and Shape:SolidMolecular weight:1058.04Ref: TM-T6194
1g414.00€10mg46.00€25mg56.00€50mg77.00€100mg117.00€200mg167.00€500mg268.00€1mL*10mM (DMSO)52.00€Adenine hydrochloride
CAS:Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry.
Formula:C5H5N5·HClPurity:98.86%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:171.59MTOB
CAS:MTOB, a CtBP substrate, inhibits CtBP-linked cancer activity in cells/mice and regulates TCF-4, affecting CSC proliferation.Formula:C5H7NaO3SPurity:98.23%Color and Shape:SolidMolecular weight:170.16Tirapazamine
CAS:Tirapazamine (Win59075) triggers apoptosis in hypoxic cells by damaging DNA and enhances effects of radiation and cisplatin.Formula:C7H6N4O2Purity:96.65% - 99.87%Color and Shape:Orange-Red Crystalline PowderMolecular weight:178.15T-5224
CAS:T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcriptionFormula:C29H27NO8Purity:97.88% - 99.29%Color and Shape:SolidMolecular weight:517.53Ref: TM-T5416
1mg48.00€5mg96.00€10mg144.00€25mg254.00€50mg424.00€100mg627.00€200mg998.00€1mL*10mM (DMSO)107.00€ISOPIMPINELLIN
CAS:Isopimpinellin (4,9-Dimethoxypsoralen) is a natural product isolated from the roots of Pimpinella saxifrage with antiviral and antileishmanial activity.Formula:C13H10O5Purity:98.74% - 99.71%Color and Shape:SolidMolecular weight:246.22Adenine hemisulfate
CAS:Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistryFormula:(C5H5N5)·H2SO4Purity:99.48%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:368.33
