DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Found 706 products of "DNA/RNA Synthesis"
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3-Deazauridine
CAS:<p>3-Deazauridine (NSC-126849), a uridine analog, blocks CTP synthesis by competing with CTP synthetase.</p>Formula:C10H13NO6Purity:99.86%Color and Shape:SolidMolecular weight:243.21T-5224
CAS:<p>T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription</p>Formula:C29H27NO8Purity:97.88% - 99.29%Color and Shape:SolidMolecular weight:517.53AI-10-49
CAS:<p>AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.</p>Formula:C30H22F6N6O5Purity:97.14%Color and Shape:SolidMolecular weight:660.52Brr2-IN-3
CAS:<p>Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa.</p>Formula:C24H20N4O3SPurity:99.26%Color and Shape:SolidMolecular weight:444.51Deoxythymidine triphosphate
CAS:<p>Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.</p>Formula:C10H14N2Na3O14P3Purity:99.78%Color and Shape:White Amorphous PowderMolecular weight:548.115-BrdU
CAS:<p>5-BrdU (Broxuridine) is a nucleoside analogue, detect proliferating cells and compete with thymidine for incorporation into DNA. High-Quality, Low-Cost!</p>Formula:C9H11BrN2O5Purity:99.54% - 99.87%Color and Shape:Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Molecular weight:307.1Phosphonoformic acid trisodium salt hexa
CAS:<p>Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) is an antiviral drug for the treatment of CMV retinitis.</p>Formula:CH12Na3O11PPurity:98%Color and Shape:SolidMolecular weight:300.03Tipiracil
CAS:<p>Tipiracil inhibits thymidine phosphorylase, enhancing trifluridine bioavailability, and is studied in colorectal and gastric cancer treatment.</p>Formula:C9H11ClN4O2Purity:99.815%Color and Shape:SolidMolecular weight:242.661,4-Anthraquinone
CAS:<p>1,4-Anthraquinone: anticancer, hinders nucleoside transport, inhibits synthesis, fragments DNA, curbs L1210 cell growth; aids HPLC analysis of NAC, CAP.</p>Formula:C14H8O2Purity:95.96% - 97.01%Color and Shape:Orange Brown SolidMolecular weight:208.21TH588 hydrochloride
CAS:<p>TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.</p>Formula:C13H13Cl3N4Color and Shape:SolidMolecular weight:331.63SCR7 pyrazine
CAS:<p>SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).</p>Formula:C18H12N4OSPurity:98.72% - 99.85%Color and Shape:SolidMolecular weight:332.38Triazavirin
CAS:<p>Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.</p>Formula:C5H7N6NaO5SPurity:99.55%Color and Shape:SolidMolecular weight:286.2CX-5461 dihydrochloride
<p>CX-5461 dihydrochloride: Oral Pol I inhibitor, HCT-116 (IC50: 142 nM), A375 (IC50: 113 nM), MIA PaCa-2 (IC50: 54 nM), weak on Pol II (IC50 ≥ 25 μM).</p>Formula:C27H29Cl2N7O2SColor and Shape:SolidMolecular weight:586.54Simeprevir
CAS:<p>Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.</p>Formula:C38H47N5O7S2Purity:99.45% - 99.92%Color and Shape:SolidMolecular weight:749.94Simeprevir sodium
CAS:<p>Simeprevir is a drug for the treatment and cure of hepatitis C.</p>Formula:C38H46N5NaO7S2Purity:98%Color and Shape:SolidMolecular weight:771.92Pyridostatin hydrochloride
CAS:<p>Pyridostatin hydrochloride stabilizes G-quadruplex DNA (Kd=490nM), inhibits cancer cell growth, and reduces SRC in breast cancer.</p>Formula:C31H37Cl5N8O5Color and Shape:SolidMolecular weight:778.941-Hydroxyanthraquinone
CAS:<p>1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities.</p>Formula:C14H8O3Purity:99.56%Color and Shape:Orange Red Needles Red-Orange To Fine Yellow CrystalsMolecular weight:224.21Dasabuvir sodium
CAS:<p>Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).</p>Formula:C26H26N3NaO5SColor and Shape:SolidMolecular weight:515.56Idarubicin hydrochloride
CAS:<p>Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).</p>Formula:C26H27NO9·HClPurity:98.91% - 99.96%Color and Shape:SolidMolecular weight:533.95BRD32048
CAS:<p>BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.</p>Formula:C16H22N6OPurity:99.87%Color and Shape:SolidMolecular weight:314.39RI-1
CAS:<p>RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).</p>Formula:C14H11Cl3N2O3Purity:99.3% - 99.62%Color and Shape:SolidMolecular weight:361.61Risdiplam
CAS:<p>Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.</p>Formula:C22H23N7OPurity:98.68% - 99.64%Color and Shape:SolidMolecular weight:401.46TH5487
CAS:<p>TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)</p>Formula:C19H18BrIN4O2Purity:98.38% - 98.73%Color and Shape:SolidMolecular weight:541.18HAMNO
CAS:<p>HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).</p>Formula:C17H13NO2Purity:99.96%Color and Shape:SolidMolecular weight:263.29BMH-21
CAS:<p>BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.</p>Formula:C21H20N4O2Purity:99.47% - 99.84%Color and Shape:SolidMolecular weight:360.41TH287
CAS:<p>TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.</p>Formula:C11H10Cl2N4Purity:97.73% - 99%Color and Shape:SolidMolecular weight:269.13Adenine hydrochloride
CAS:<p>Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry.</p>Formula:C5H5N5·HClPurity:98.86%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:171.59Lurbinectedin
CAS:<p>Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.</p>Formula:C41H44N4O10SPurity:98.11%Color and Shape:SolidMolecular weight:784.87FIT-039
CAS:<p>FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).</p>Formula:C17H18FN3SPurity:98.61%Color and Shape:SolidMolecular weight:315.41Fosifloxuridine nafalbenamide
CAS:<p>Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.</p>Formula:C29H29FN3O9PPurity:95.87%Color and Shape:SolidMolecular weight:613.53Brequinar
CAS:<p>Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.</p>Formula:C23H15F2NO2Purity:99.1% - 99.57%Color and Shape:SolidMolecular weight:375.37L-Asparaginase
CAS:<p>L-Asparaginase, an enzyme for acute lymphoblastic leukemia treatment, is administered via injection.</p>Formula:NAPurity:97%Color and Shape:SolidMolecular weight:N/ARCM-1
CAS:<p>RCM-1 is an inhibitor of FOXM1.</p>Formula:C20H12N2OS4Purity:98.08%Color and Shape:SolidMolecular weight:424.58EG1
CAS:<p>EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.</p>Formula:C22H18N2O5Purity:97.48%Color and Shape:SolidMolecular weight:390.39CB-6644
CAS:<p>CB-6644 is a small molecule inhibitor of the ATPase activity of the RUVBL1/2 complex.Cost-effective and quality-assured.</p>Formula:C29H34ClFN4O5Purity:96.33% - 99.85%Color and Shape:SolidMolecular weight:573.06FUBP1-IN-1
CAS:<p>FUBP1-in-1: Potent FUBP1 inhibitor with 11.0 M IC50, disrupts FUBP1-DNA binding.</p>Formula:C19H14F3N3O2SPurity:99.7%Color and Shape:SolidMolecular weight:405.392′-O-Methylcytidine
CAS:<p>2′-O-Methylcytidine inhibits NS5B-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.</p>Formula:C10H15N3O5Purity:99.72%Color and Shape:SolidMolecular weight:257.24Gadodiamide
CAS:<p>Gadodiamide is an MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.</p>Formula:C16H26GdN5O8Purity:99.86%Color and Shape:SolidMolecular weight:573.66Antitumor agent-152
CAS:<p>Organic compound, potential dCK inhibitor, with 2-ethyl-3-methoxyphenyl-1,3-thiazole and pyrimidine units.</p>Formula:C17H19N5O2S2Purity:95.00%Color and Shape:SolidMolecular weight:389.5C/EBPα inducer 1
CAS:<p>C/EBPα inducer 1 (4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-) is a potential inducer of myeloid differentiation via</p>Formula:C20H12FN3O4Purity:98.99%Color and Shape:SolidMolecular weight:377.33Myoseverin
CAS:<p>Myoseverin triggers myotube fission into single cells, influencing genes for growth, immunity, matrix remodeling, and stress, aiding healing and regeneration.</p>Formula:C24H28N6O2Purity:99.25%Color and Shape:SolidMolecular weight:432.52VPC-80051 racemate
CAS:<p>VPC-80051 is the first small molecule inhibitor of hnRNP A1 splicing activity by using a computer-aided drug discovery approach.</p>Formula:C16H13F2N3OPurity:97.36%Color and Shape:SolidMolecular weight:301.295'-Deoxy-5-fluorocytidine
CAS:<p>5'-Deoxy-5-fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine.</p>Formula:C9H12FN3O4Purity:99.67%Color and Shape:White SolidMolecular weight:245.21TC-E 5003
CAS:<p>TC-E 5003 (NSC-30176) is a selective inhibitor of PRMT1 with IC50 of 1.5 μM.</p>Formula:C16H14Cl2N2O4SPurity:97.01%Color and Shape:SolidMolecular weight:401.26HALOFUGINONE LACTATE
CAS:<p>HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.</p>Formula:C19H23BrClN3O6Purity:99.70% - 99.96%Color and Shape:SolidMolecular weight:504.8Euscaphic acid
CAS:<p>Euscaphic acid has anti-diabetic and anti-inflammatory effects, blocking IKK/MAPKs and NF-κB activation by disrupting TRAF6/IRAK1/TAK1 clustering.</p>Formula:C30H48O5Purity:98.93%Color and Shape:SolidMolecular weight:488.7Clevudine
CAS:<p>Clevudine (Levovir) fights HBV, blocks viral DNA synthesis, and has a long half-life reducing relapse risk after treatment.</p>Formula:C10H13FN2O5Purity:99.88% - 99.97%Color and Shape:SolidMolecular weight:260.22dGTP
CAS:<p>dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and</p>Formula:C10H16N5O13P3Purity:99.64%Color and Shape:SolidMolecular weight:507.18L67
CAS:<p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>Formula:C16H14Br2N4O4Purity:98.34% - 99.56%Color and Shape:SolidMolecular weight:486.11Pseudouridine
CAS:<p>Pseudouridine, prevalent in non-coding RNAs, boosts tRNA and rRNA function by RNA stabilization.</p>Formula:C9H12N2O6Purity:99.3%Color and Shape:SolidMolecular weight:244.2
