PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
GSK2334470
CAS:1227911-45-6
GSK2334470 is a novel PDK1 inhibitor (IC50: ~10 nM, in a cell-free assay), with no …
Formula:
C25H34N8O
Purity:
99.04% - 99.87%
Color and Shape:
Solid
Molecular weight:
462.59
Ref: TM-T2348
| 5mg | 52.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 143.00 € | ||
| 50mg | 252.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Naquotinib
CAS:1448232-80-1
Naquotinib (ASP8273) (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM …
Formula:
C30H42N8O3
Purity:
97.49%
Color and Shape:
Solid
Molecular weight:
562.71
Ref: TM-TQ0092
| 1mg | 51.00 € | ||
| 2mg | 66.00 € | ||
| 5mg | 95.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 132.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
VO-Ohpic trihydrate
CAS:476310-60-8
VO-Ohpic trihydrate (VO-Ohpic) is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 …
Formula:
C12H9N2O8V·3H2O·H
Purity:
100%
Color and Shape:
Solid
Molecular weight:
415.2
Ref: TM-T7012
| 5mg | 56.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 142.00 € | ||
| 50mg | 245.00 € | ||
| 100mg | 352.00 € | ||
| 200mg | 525.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Samotolisib
CAS:1386874-06-1
Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.
Formula:
C23H26N4O3
Purity:
98.41% - 99.69%
Color and Shape:
Solid
Molecular weight:
406.48
Ref: TM-T6883
| 5mg | 48.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 149.00 € | ||
| 50mg | 250.00 € | ||
| 100mg | 368.00 € | ||
| 200mg | 523.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Omipalisib
CAS:1086062-66-9
Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.
Formula:
C25H17F2N5O3S
Purity:
98% - 99.8%
Color and Shape:
Solid
Molecular weight:
505.5
Ref: TM-T1861
| 5mg | 62.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 272.00 € | ||
| 100mg | 417.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TBB
CAS:17374-26-4
TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).
Formula:
C6HBr4N3
Purity:
98.51% - 99.45%
Color and Shape:
Off-White Solid
Molecular weight:
434.71
Ref: TM-T2695
| 5mg | 45.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 73.00 € | ||
| 50mg | 87.00 € | ||
| 100mg | 119.00 € | ||
| 200mg | 173.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AMG319
CAS:1608125-21-8
AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity …
Formula:
C21H16FN7
Purity:
98.57% - 98.9%
Color and Shape:
Crystalline Solid
Molecular weight:
385.4
Ref: TM-T6757
| 2mg | 49.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 225.00 € | ||
| 50mg | 384.00 € | ||
| 100mg | 554.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TDZD-8
CAS:327036-89-5
TDZD-8 (NP 01139) is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal …
Formula:
C10H10N2O2S
Purity:
97.13% - 99.48%
Color and Shape:
White Solid
Molecular weight:
222.26
Ref: TM-T6187
| 5mg | 49.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 122.00 € | ||
| 100mg | 184.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Idelalisib
CAS:870281-82-6
Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 …
Formula:
C22H18FN7O
Purity:
98% - 99.94%
Color and Shape:
Solid
Molecular weight:
415.42
Ref: TM-T1894
| 5mg | 35.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 73.00 € | ||
| 50mg | 92.00 € | ||
| 100mg | 107.00 € | ||
| 200mg | 138.00 € | ||
| 500mg | 221.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ZSTK474
CAS:475110-96-4
PI3K Inhibitor ZSTK474 is an orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with …
Formula:
C19H21F2N7O2
Purity:
98.29% - 99.76%
Color and Shape:
White Powder
Molecular weight:
417.41
Ref: TM-T6168
| 5mg | 38.00 € | ||
| 10mg | 49.00 € | ||
| 25mg | 64.00 € | ||
| 50mg | 78.00 € | ||
| 100mg | 96.00 € | ||
| 200mg | 139.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Alflutinib
CAS:1869057-83-9
Alflutinib (ASK120067) is an inhibitor of EGFR, and its targets including EGFR activating mutations and …
Formula:
C28H31F3N8O2
Purity:
99.61%
Color and Shape:
Solid
Molecular weight:
568.59
Ref: TM-T22254
| 1mg | 210.00 € | ||
| 5mg | 428.00 € | ||
| 10mg | 610.00 € | ||
| 25mg | 920.00 € | ||
| 50mg | 1,295.00 € | ||
| 100mg | 1,755.00 € | ||
| 1mL*10mM (DMSO) | 556.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
KI8751
CAS:228559-41-9
KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.
Formula:
C24H18F3N3O4
Purity:
99.73% - 99.9%
Color and Shape:
Solid
Molecular weight:
469.41
Ref: TM-T2446
| 2mg | 36.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 84.00 € | ||
| 25mg | 153.00 € | ||
| 50mg | 289.00 € | ||
| 100mg | 508.00 € | ||
| 200mg | 660.00 € | ||
| 500mg | 1,003.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(±)-Norcantharidin
CAS:29745-04-8
(±)-Norcantharidin (Endothall anhydride) is a synthetic anticancer compound which is a dual inhibitor for c-Met …
Formula:
C8H8O4
Purity:
99.43% - ≥98%
Color and Shape:
Solid
Molecular weight:
168.15
Ref: TM-T5656
| 1g | 530.00 € | ||
| 5mg | 44.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 77.00 € | ||
| 50mg | 103.00 € | ||
| 100mg | 151.00 € | ||
| 500mg | 357.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WS6
CAS:1421227-53-3
WS6, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase …
Formula:
C29H31F3N6O3
Purity:
97.23% - 99.83%
Color and Shape:
Solid
Molecular weight:
568.59
Ref: TM-T2106
| 1mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 84.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 220.00 € | ||
| 100mg | 327.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Voxtalisib
CAS:934493-76-2
Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 …
Formula:
C13H14N6O
Purity:
98.01% - 99.36%
Color and Shape:
Solid
Molecular weight:
270.29
Ref: TM-T7014
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 237.00 € | ||
| 50mg | 380.00 € | ||
| 100mg | 552.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AEE788
CAS:497839-62-0
AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, …
Formula:
C27H32N6
Purity:
100% - 98.94%
Color and Shape:
Solid
Molecular weight:
440.58
Ref: TM-T2116
| 2mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 319.00 € | ||
| 100mg | 481.00 € | ||
| 500mg | 1,078.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Trastuzumab
CAS:180288-69-1
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2.
Purity:
98% - 99.50%
Color and Shape:
Solid
Molecular weight:
Approximately 145.53 kDa
Ref: TM-T9912
| 1mg | 152.00 € | ||
| 5mg | 511.00 € | ||
| 10mg | 640.00 € | ||
| 25mg | 1,009.00 € | ||
| 50mg | 1,364.00 € | ||
| 100mg | 1,831.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
RSVA405
CAS:140405-36-3
RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitor
Formula:
C17H20N4O2
Purity:
98.71%
Color and Shape:
Solid
Molecular weight:
312.37
Ref: TM-T8476
| 5mg | 52.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 225.00 € | ||
| 100mg | 323.00 € | ||
| 200mg | 452.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Umbralisib
CAS:1532533-67-7
Umbralisib (TGR 1202) is a PI3Kδ inhibitor.
Formula:
C31H24F3N5O3
Purity:
99.56% - 99.83%
Color and Shape:
White Solid
Molecular weight:
571.55
Ref: TM-T4976
| 1mg | 48.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 335.00 € | ||
| 50mg | 440.00 € | ||
| 100mg | 644.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Sulforaphene
CAS:592-95-0
Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for …
Formula:
C6H9NOS2
Purity:
98.01% - 99.19%
Color and Shape:
Slightly Yellowish Liquid
Molecular weight:
175.27
Ref: TM-TL0016
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 222.00 € | ||
| 50mg | 331.00 € | ||
| 100mg | 489.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
