PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
PD153035 hydrochloride
CAS:183322-45-4
PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR; few influence against …
Formula:
C16H15BrClN3O2
Purity:
100% - ≥95%
Color and Shape:
Solid
Molecular weight:
396.67
Ref: TM-T1761
| 5mg | 35.00 € | ||
| 10mg | 44.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 142.00 € | ||
| 100mg | 233.00 € | ||
| 500mg | 530.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Eganelisib
CAS:1693758-51-8
Eganelisib (IPI-549) is an inhibitor of PI3Kγ (IC50 = 16, 3,200, 3,500, and >8,400 nM …
Formula:
C30H24N8O2
Purity:
98% - 99.56%
Color and Shape:
Solid
Molecular weight:
528.56
Ref: TM-T5432
| 5mg | 48.00 € | ||
| 10mg | 71.00 € | ||
| 25mg | 111.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 332.00 € | ||
| 500mg | 811.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AMG 511
CAS:1253573-53-3
AMG 511: oral class I PI3K inhibitor (α, β, δ, γ Kis: 4, 6, 2, …
Formula:
C22H28FN9O3S
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
517.58
Ref: TM-T14214
| 1mg | 91.00 € | ||
| 2mg | 106.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 283.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ZM39923 hydrochloride
CAS:1021868-92-7
ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and …
Formula:
C23H25NO·HCl
Purity:
98.05%
Color and Shape:
Solid
Molecular weight:
367.91
Ref: TM-T6145
| 5mg | 58.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 168.00 € | ||
| 50mg | 304.00 € | ||
| 100mg | 455.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SB 216763
CAS:280744-09-4
SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).
Formula:
C19H12Cl2N2O2
Purity:
99.13% - 99.61%
Color and Shape:
Solid
Molecular weight:
371.22
Ref: TM-T3077
| 2mg | 39.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 128.00 € | ||
| 50mg | 193.00 € | ||
| 100mg | 326.00 € | ||
| 500mg | 789.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WZ4003
CAS:1214265-58-3
WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 …
Formula:
C25H29ClN6O3
Purity:
100% - 97.88%
Color and Shape:
Solid
Molecular weight:
496.99
Ref: TM-T6291
| 5mg | 50.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 115.00 € | ||
| 50mg | 172.00 € | ||
| 100mg | 249.00 € | ||
| 200mg | 369.00 € | ||
| 500mg | 609.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SU5214
CAS:186611-04-1
SU5214 is a modulator of tyrosine kinase signal transduction.
Formula:
C16H13NO2
Purity:
99.52% - 99.55%
Color and Shape:
Solid
Molecular weight:
251.28
Ref: TM-T3569
| 5mg | 38.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 107.00 € | ||
| 50mg | 169.00 € | ||
| 100mg | 269.00 € | ||
| 200mg | 391.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
EAI045
CAS:1942114-09-1
EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.
Formula:
C19H14FN3O3S
Purity:
99.36% - 99.73%
Color and Shape:
Solid
Molecular weight:
383.4
Ref: TM-T6824
| 5mg | 43.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 91.00 € | ||
| 50mg | 123.00 € | ||
| 100mg | 195.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Canertinib dihydrochloride
CAS:289499-45-2
Canertinib dihydrochloride (PD-183805 dihydrochloride) is the hydrochloride salt of an orally bio-available quinazoline with potential …
Formula:
C24H27Cl3FN5O3
Purity:
99.23%
Color and Shape:
Solid
Molecular weight:
558.86
Ref: TM-T2501
| 5mg | 38.00 € | ||
| 10mg | 52.00 € | ||
| 50mg | 74.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
iMDK
CAS:881970-80-5
iMDK quarterhydrate, a PI3K inhibitor, blocks MDK growth factor and enhances NSCLC treatment with MEK …
Formula:
C21H13FN2O2S
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
376.4
Ref: TM-T9460
| 1mg | 58.00 € | ||
| 5mg | 123.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 424.00 € | ||
| 50mg | 628.00 € | ||
| 100mg | 888.00 € | ||
| 500mg | 1,790.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Vps34-PIK-III
CAS:1383716-40-2
Vps34-PIK-III (VPS34-IN2), a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and results in the …
Formula:
C17H17N7
Purity:
98.39% - 98.43%
Color and Shape:
Solid
Molecular weight:
319.36
Ref: TM-T6945
| 1mg | 51.00 € | ||
| 2mg | 70.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 198.00 € | ||
| 25mg | 443.00 € | ||
| 50mg | 651.00 € | ||
| 100mg | 922.00 € | ||
| 500mg | 1,848.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Chrysophanol
CAS:481-74-3
Chrysophanol (Turkey Rhubarb) is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, and …
Formula:
C15H10O4
Purity:
97.91% - 99.7%
Color and Shape:
Physical Description Golden Yellow Plates Or Brown Powder Melting Point 196°C
Molecular weight:
254.24
Ref: TM-T2995
| 50mg | 43.00 € | ||
| 100mg | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Indirubin-3'-monoxime
CAS:160807-49-8
Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs …
Formula:
C16H11N3O2
Purity:
99.65%
Color and Shape:
Dark Red Solid
Molecular weight:
277.28
Ref: TM-T5200
| 1mg | 35.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 186.00 € | ||
| 50mg | 294.00 € | ||
| 100mg | 438.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
MK-3903
CAS:1219737-12-8
MK-3903 is a potent and selective AMPK activator (EC50: 8 nM).
Formula:
C27H19ClN2O3
Purity:
98.54% - 98.63%
Color and Shape:
Solid
Molecular weight:
454.9
Ref: TM-T5187
| 1mg | 36.00 € | ||
| 5mg | 77.00 € | ||
| 10mg | 117.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 341.00 € | ||
| 100mg | 566.00 € | ||
| 200mg | 823.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Cetuximab
CAS:205923-56-4
Cetuximab (C225) is a monoclonal antibody that is an inhibitor of human epidermal growth factor …
Formula:
C107H179N35O36S7
Purity:
100.00% - SDS-PAGE:98.4%；SEC-HPLC: 99.7%
Color and Shape:
Liquid
Molecular weight:
152 kDa
Ref: TM-T9905
| 1mg | 185.00 € | ||
| 2mg | 269.00 € | ||
| 5mg | 448.00 € | ||
| 10mg | 648.00 € | ||
| 25mg | 1,013.00 € | ||
| 50mg | 1,365.00 € | ||
| 100mg | 1,839.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ONO-7475
CAS:1646839-59-9
ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase
Formula:
C32H26N4O6
Purity:
98.74%
Color and Shape:
Solid
Molecular weight:
562.57
Ref: TM-T8327
| 1mg | 62.00 € | ||
| 5mg | 135.00 € | ||
| 10mg | 209.00 € | ||
| 25mg | 353.00 € | ||
| 50mg | 525.00 € | ||
| 100mg | 738.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WH-4-025
CAS:1876463-35-2
WH-4-025 is a Salt-inducible kinase (SIK) inhibitor.
Formula:
C39H38F3N7O5
Purity:
99.41%
Color and Shape:
Solid
Molecular weight:
741.76
Ref: TM-T9219
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 135.00 € | ||
| 25mg | 261.00 € | ||
| 50mg | 414.00 € | ||
| 100mg | 609.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Methyl 2,5-dihydroxycinnamate
CAS:63177-57-1
Methyl 2,5-dihydroxycinnamate is an EGF receptor-associated tyrosine kinases inhibitor.
Formula:
C10H10O4
Purity:
98.98%
Color and Shape:
Crystalline
Molecular weight:
194.18
Ref: TM-T22974
| 5mg | 60.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 522.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PS47
CAS:1180676-33-8
PS-47(PS 47) is an inactive E-isomer of PS48. PS48 is an activator of PDK1.
Formula:
C17H15ClO2
Purity:
99.09%
Color and Shape:
Solid
Molecular weight:
286.75
Ref: TM-T24677
| 5mg | 44.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 181.00 € | ||
| 100mg | 299.00 € | ||
| 200mg | 420.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PIK-293
CAS:900185-01-5
PIK-293 is a PI3K inhibitor, for PI3Kδ( IC50=0.24 μM), and less potent for PI3Kα/β/ γ.
Formula:
C22H19N7O
Purity:
99.8%
Color and Shape:
Solid
Molecular weight:
397.43
Ref: TM-T3348
| 1mg | 48.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 270.00 € | ||
| 50mg | 409.00 € | ||
| 100mg | 590.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
