PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
ALK-IN-1
CAS:1197958-12-5
ALK-IN-1 (AP26113) is a potent ALK inhibitor, demonstrated ability overcome Crizotinib resistance mediated by a …
Formula:
C26H34ClN6O2P
Purity:
100% - 97.66%
Color and Shape:
Solid
Molecular weight:
529.01
Ref: TM-T3059
| 5mg | 48.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 143.00 € | ||
| 100mg | 232.00 € | ||
| 200mg | 345.00 € | ||
| 500mg | 561.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ETP-45658
CAS:1198357-79-7
ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 …
Formula:
C16H17N5O2
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
311.34
Ref: TM-T25399
| 1mg | 52.00 € | ||
| 5mg | 110.00 € | ||
| 10mg | 174.00 € | ||
| 25mg | 313.00 € | ||
| 50mg | 505.00 € | ||
| 100mg | 738.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Zorifertinib
CAS:1626387-80-1
Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.
Formula:
C22H23ClFN5O3
Purity:
98.29% - 99.36%
Color and Shape:
White To Off-White Solid
Molecular weight:
459.9
Ref: TM-T3659
| 25mg | 43.00 € | ||
| 50mg | 56.00 € | ||
| 100mg | 88.00 € | ||
| 200mg | 116.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
MTX-211
CAS:1952236-05-3
MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and …
Formula:
C20H14Cl2FN5O2S
Purity:
100% - 97.28%
Color and Shape:
Solid
Molecular weight:
478.33
Ref: TM-T4296
| 1mg | 62.00 € | ||
| 5mg | 180.00 € | ||
| 10mg | 273.00 € | ||
| 25mg | 450.00 € | ||
| 50mg | 621.00 € | ||
| 100mg | 840.00 € | ||
| 200mg | 1,116.00 € | ||
| 1mL*10mM (DMSO) | 183.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Desmethyl Erlotinib hydrochloride
CAS:183320-51-6
Desmethyl Erlotinib hydrochloride (OSI 420) is an active metabolite of erlotinib which is an orally …
Formula:
C21H21N3O4·HCl
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
415.87
Ref: TM-T6619
| 1mg | 59.00 € | ||
| 2mg | 82.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 186.00 € | ||
| 25mg | 332.00 € | ||
| 50mg | 499.00 € | ||
| 100mg | 711.00 € | ||
| 200mg | 591.00 € | ||
| 1mL*10mM (DMSO) | 126.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PF-06409577
CAS:1467057-23-3
PF-06409577 is an effective, orally active, and specific allosteric activator of AMPK (EC50: 7 nM, …
Formula:
C19H16ClNO3
Purity:
95.17% - 98.16%
Color and Shape:
Solid
Molecular weight:
341.79
Ref: TM-T4427
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 104.00 € | ||
| 25mg | 209.00 € | ||
| 50mg | 377.00 € | ||
| 100mg | 561.00 € | ||
| 500mg | 1,210.00 € | ||
| 1mL*10mM (DMSO) | 74.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
R547
CAS:741713-40-6
R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 …
Formula:
C18H21F2N5O4S
Purity:
90% - 99.84%
Color and Shape:
Solid
Molecular weight:
441.45
Ref: TM-T6312
| 1mg | 49.00 € | ||
| 2mg | 73.00 € | ||
| 5mg | 107.00 € | ||
| 10mg | 155.00 € | ||
| 25mg | 282.00 € | ||
| 50mg | 542.00 € | ||
| 100mg | 777.00 € | ||
| 200mg | 631.00 € | ||
| 500mg | 1,568.00 € | ||
| 1mL*10mM (DMSO) | 127.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
5-Bromoindole
CAS:10075-50-0
5-bromoindole is a potential inhibitor of glycogen synthase kinase 3 (GSK-3)and an important pharmaceutical chemical …
Formula:
C8H6BrN
Purity:
99.99%
Color and Shape:
White To Beige Crystalline Powder
Molecular weight:
196.04
Ref: TM-T7473
| 1g | 34.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AG-1478
CAS:153436-53-4
AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.
Formula:
C16H14ClN3O2
Purity:
99.03% - 99.71%
Color and Shape:
Solid
Molecular weight:
315.75
Ref: TM-T2047
| 5mg | 54.00 € | ||
| 10mg | 71.00 € | ||
| 25mg | 115.00 € | ||
| 50mg | 198.00 € | ||
| 100mg | 273.00 € | ||
| 200mg | 355.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AG 555
CAS:133550-34-2
AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.
Formula:
C19H18N2O3
Purity:
100% - 99.51%
Color and Shape:
Solid
Molecular weight:
322.36
Ref: TM-T4326
| 5mg | 46.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 110.00 € | ||
| 50mg | 167.00 € | ||
| 100mg | 243.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PF-04802367
CAS:1962178-27-3
PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on …
Formula:
C16H16ClN5O3
Purity:
98.76%
Color and Shape:
Solid
Molecular weight:
361.78
Ref: TM-T9611
| 1mg | 51.00 € | ||
| 5mg | 102.00 € | ||
| 10mg | 155.00 € | ||
| 25mg | 269.00 € | ||
| 50mg | 406.00 € | ||
| 100mg | 543.00 € | ||
| 200mg | 717.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Benidipine hydrochloride
CAS:91599-74-5
Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker …
Formula:
C28H32ClN3O6
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
542.03
Ref: TM-T6227
| 1g | 130.00 € | ||
| 50mg | 36.00 € | ||
| 100mg | 48.00 € | ||
| 200mg | 61.00 € | ||
| 500mg | 90.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ridaforolimus
CAS:572924-54-0
Ridaforolimus (AP23573), a rapamycin analogue, inhibits mTOR to potentially arrest tumor growth/proliferation via PI3K/Akt pathway.
Formula:
C53H84NO14P
Purity:
90.00% - 98.55%
Color and Shape:
Off-White Solid
Molecular weight:
990.21
Ref: TM-T6334
| 5mg | 55.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 159.00 € | ||
| 50mg | 278.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
DMH-25
CAS:1685280-21-0
DMH25 is a novel covalent and potent inhibitor of mTOR and shows in vivo antitumor …
Formula:
C15H8Br3NO3
Purity:
99.26%
Color and Shape:
Solid
Molecular weight:
489.94
Ref: TM-T8569
| 1mg | 84.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 248.00 € | ||
| 25mg | 408.00 € | ||
| 50mg | 574.00 € | ||
| 100mg | 776.00 € | ||
| 200mg | 1,029.00 € | ||
| 1mL*10mM (DMSO) | 203.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
OTSSP167
CAS:1431697-89-0
OTSSP167 (OTS167) is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with …
Formula:
C25H28Cl2N4O2
Purity:
98.22% - 99.47%
Color and Shape:
Solid
Molecular weight:
487.42
Ref: TM-T1759
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 425.00 € | ||
| 500mg | 922.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AS-041164
CAS:6318-41-8
AS-041164: Oral PI3Kγ inhibitor, IC50 70 nM; weaker on PI3Kα/β/δ; anti-inflammatory.
Formula:
C11H7NO4S
Purity:
99.59%
Color and Shape:
Solid
Molecular weight:
249.24
Ref: TM-T21938
| 10mg | 44.00 € | ||
| 25mg | 79.00 € | ||
| 50mg | 129.00 € | ||
| 100mg | 201.00 € | ||
| 200mg | 266.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Desmethyl Erlotinib
CAS:183321-86-0
Desmethyl Erlotinib (CP-473420) is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 …
Formula:
C21H21N3O4
Purity:
98.62%
Color and Shape:
Solid
Molecular weight:
379.41
Ref: TM-T6328
| 1mg | 52.00 € | ||
| 2mg | 75.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 324.00 € | ||
| 50mg | 489.00 € | ||
| 100mg | 703.00 € | ||
| 1mL*10mM (DMSO) | 126.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WHI-P258
CAS:21561-09-1
WHI-P258, a weak JAK3 inhibitor, is used as a negative control in drug development.
Formula:
C16H15N3O2
Purity:
99.59% - 99.95%
Color and Shape:
Solid
Molecular weight:
281.31
Ref: TM-T2035
| 5mg | 34.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 140.00 € | ||
| 100mg | 230.00 € | ||
| 200mg | 336.00 € | ||
| 1mL*10mM (DMSO) | 39.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
IC-87114
CAS:371242-69-2
IC-87114 is a specific PI3Kδ inhibitor(IC50=0.5 μM).
Formula:
C22H19N7O
Purity:
100% - 97.97%
Color and Shape:
Solid
Molecular weight:
397.43
Ref: TM-T2660
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 144.00 € | ||
| 50mg | 237.00 € | ||
| 100mg | 373.00 € | ||
| 200mg | 541.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PQR620
CAS:1927857-56-4
PQR620 is a novel potent and selective, brain penetrant inhibitor of mTORC1/2.
Formula:
C21H25F2N7O2
Purity:
97.61%
Color and Shape:
Solid
Molecular weight:
445.47
Ref: TM-T5472
| 1mg | 62.00 € | ||
| 5mg | 145.00 € | ||
| 10mg | 203.00 € | ||
| 25mg | 342.00 € | ||
| 50mg | 487.00 € | ||
| 100mg | 653.00 € | ||
| 200mg | 881.00 € | ||
| 1mL*10mM (DMSO) | 141.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
