PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
Subcategories of "PI3K/Akt/mTOR Signaling"
- AMPK(171 products)
- ATM/ATR(72 products)
- DNA-PK(48 products)
- EGFR(591 products)
- MELK(7 products)
- PDK(9 products)
- PI3K(233 products)
- S6 Kinase(8 products)
- gsk-3(110 products)
- mTOR(162 products)
Show 2 more subcategories
Found 1007 products of "PI3K/Akt/mTOR Signaling"
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ETP-45658
CAS:ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively).Formula:C16H17N5O2Purity:99.14%Color and Shape:SolidMolecular weight:311.34Ref: TM-T25399
1mg52.00€5mg111.00€10mg175.00€25mg316.00€50mg512.00€100mg747.00€1mL*10mM (DMSO)124.00€Zorifertinib
CAS:Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.Formula:C22H23ClFN5O3Purity:98.20% - 99.36%Color and Shape:White To Off-White SolidMolecular weight:459.9MTX-211
CAS:MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Formula:C20H14Cl2FN5O2SPurity:97.6% - >99.99%Color and Shape:SolidMolecular weight:478.33Ref: TM-T4296
1mg64.00€2mg95.00€5mg170.00€10mg274.00€25mg464.00€50mg640.00€100mg847.00€200mg1,159.00€1mL*10mM (DMSO)180.00€R547
CAS:R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM.Formula:C18H21F2N5O4SPurity:90% - 99.64%Color and Shape:SolidMolecular weight:441.45Ref: TM-T6312
1mg50.00€5mg101.00€10mg147.00€25mg268.00€50mg515.00€100mg740.00€200mg1,026.00€1mL*10mM (DMSO)120.00€5-Bromoindole
CAS:<p>5-bromoindole is a potential inhibitor of glycogen synthase kinase 3 (GSK-3)and an important pharmaceutical chemical intermediate</p>Formula:C8H6BrNPurity:99.99%Color and Shape:White To Beige Crystalline PowderMolecular weight:196.04AG-1478
CAS:<p>AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.</p>Formula:C16H14ClN3O2Purity:99.03% - 99.71%Color and Shape:SolidMolecular weight:315.75AG 555
CAS:AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.Formula:C19H18N2O3Purity:98.02% - 99.94%Color and Shape:SolidMolecular weight:322.36PF-04802367
CAS:PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay.Formula:C16H16ClN5O3Purity:98.76%Color and Shape:SolidMolecular weight:361.78Ref: TM-T9611
1mg52.00€5mg105.00€10mg160.00€25mg279.00€50mg420.00€100mg562.00€200mg743.00€1mL*10mM (DMSO)117.00€DMH-25
CAS:<p>DMH25 is a novel covalent and potent inhibitor of mTOR and shows in vivo antitumor activity against triple-negative breast cancer cells.</p>Formula:C15H8Br3NO3Purity:99.26%Color and Shape:SolidMolecular weight:489.94OTSSP167
CAS:OTSSP167 (OTS167) is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity.Formula:C25H28Cl2N4O2Purity:98.22% - 99.47%Color and Shape:SolidMolecular weight:487.42Ref: TM-T1759
1mg40.00€2mg51.00€5mg88.00€10mg119.00€25mg187.00€50mg283.00€100mg432.00€500mg938.00€1mL*10mM (DMSO)96.00€AS-041164
CAS:AS-041164: Oral PI3Kγ inhibitor, IC50 70 nM; weaker on PI3Kα/β/δ; anti-inflammatory.Formula:C11H7NO4SPurity:99.45%Color and Shape:SolidMolecular weight:249.24WHI-P258
CAS:WHI-P258, a weak JAK3 inhibitor, is used as a negative control in drug development.Formula:C16H15N3O2Purity:99.66% - 99.92%Color and Shape:SolidMolecular weight:281.31IC-87114
CAS:<p>IC-87114 is a specific PI3Kδ inhibitor(IC50=0.5 μM).</p>Formula:C22H19N7OPurity:99.30% - >99.99%Color and Shape:SolidMolecular weight:397.43PQR620
CAS:PQR620 is a novel potent and selective, brain penetrant inhibitor of mTORC1/2.Formula:C21H25F2N7O2Purity:97.61%Color and Shape:SolidMolecular weight:445.47CC-115
CAS:CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).Formula:C16H16N8OPurity:86.79% - 99.01%Color and Shape:SolidMolecular weight:336.35PQR530
CAS:PQR530, a potent dual PI3K/mTORC1/2 inhibitor, blocks PKB and pS6 phosphorylation (IC50: 0.07 μM) and has antitumor properties.Formula:C18H23F2N7O2Purity:99.5%Color and Shape:SolidMolecular weight:407.42Olmutinib
CAS:Olmutinib is an oral mutant-specific EGFR inhibitor for cancer treatment with potential lower toxicity.Formula:C26H26N6O2SPurity:99.14% - 99.63%Color and Shape:SolidMolecular weight:486.59Ref: TM-T6918
2mg39.00€5mg57.00€10mg88.00€25mg137.00€50mg180.00€100mg283.00€200mg462.00€1mL*10mM (DMSO)59.00€EBE-A22
CAS:EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.Formula:C17H16BrN3O2Purity:99.087% - 99.88%Color and Shape:SolidMolecular weight:374.23Tesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C24H25Cl2FN4O2Purity:97.89% - 98.66%Color and Shape:SolidMolecular weight:491.39Ref: TM-TQ0166
1mg107.00€2mg156.00€5mg236.00€10mg457.00€25mg750.00€50mg1,026.00€1mL*10mM (DMSO)255.00€YU238259
CAS:YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining (NHEJ), in cell-based GFP reporter assays.Formula:C22H22ClN3O4SPurity:99.28% - 99.56%Color and Shape:SolidMolecular weight:459.95Ref: TM-T4339
1mg48.00€2mg63.00€5mg87.00€10mg153.00€25mg305.00€50mg543.00€100mg780.00€500mg1,605.00€1mL*10mM (DMSO)87.00€
