PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
Epitinib succinate
CAS:2252334-12-4
Epitinib succinate (HMPL-813 succinate) is an orally active and brain penetration EGFR tyrosine kinase inhibitor …
Formula:
C28H32N6O6
Purity:
97.43% - 99.47%
Color and Shape:
Solid
Molecular weight:
548.59
Ref: TM-T35914
| 1mg | 74.00 € | ||
| 2mg | 95.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 266.00 € | ||
| 25mg | 440.00 € | ||
| 50mg | 602.00 € | ||
| 100mg | 825.00 € | ||
| 500mg | 1,653.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
PF-249
CAS:1467059-70-6
PF-249 (PF-06685249) is a β1-selective AMPK with an EC50 of 12 nM for AMPK α1β1γ1 …
Formula:
C17H16ClN3O3
Purity:
97.02%
Color and Shape:
Solid
Molecular weight:
345.78
Ref: TM-T24626
| 1mg | 48.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 151.00 € | ||
| 25mg | 243.00 € | ||
| 50mg | 353.00 € | ||
| 100mg | 495.00 € | ||
| 200mg | 680.00 € | ||
| 1mL*10mM (DMSO) | 103.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
PI3K-IN-6
CAS:1842380-77-1
PI3K-IN-6 is an oral active and highly selective inhibitor of phosphoinositide 3-kinase (PI3K) β/δ(IC50 values …
Formula:
C17H14Cl2FN9O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
450.26
Ref: TM-T12457
| 25mg | 1,406.00 € | ||
| 50mg | 1,847.00 € | ||
| 100mg | 2,331.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Nimotuzumab
CAS:828933-51-3
Nimotuzumab is a humanized therapeutic monoclonal antibody against epidermal growth factor receptor EGFR).
Purity:
95.00%
Color and Shape:
Solid
Ref: TM-T9923
| 1mg | 438.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
GLPG3970
CAS:2403733-82-2
GLPG3970, a pioneering inhibitor of SIK2/SIK3, is utilized in the investigation of inflammation and autoimmune …
Formula:
C25H27F3N4O4
Purity:
100% - 99.60%
Color and Shape:
Liquid
Molecular weight:
504.5
Ref: TM-T73384
| 1mg | 132.00 € | ||
| 5mg | 315.00 € | ||
| 10mg | 468.00 € | ||
| 25mg | 747.00 € | ||
| 50mg | 1,059.00 € | ||
| 100mg | 1,409.00 € | ||
| 1mL*10mM (DMSO) | 352.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
HL271
CAS:1422365-52-3
HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 …
Formula:
C13H17ClF3N5O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
351.76
Ref: TM-T11570
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
PI3Kα-IN-13
CAS:2955529-67-4
PI3Kα-IN-13 (Compound 18a), a PI3Kα inhibitor with an IC50 of 2.5 nM, effectively induces apoptosis …
Formula:
C21H19N5O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
389.41
Ref: TM-T79685
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
mTOR inhibitor-2
CAS:2219323-96-1
mTOR inhibitor-2 is an inhibitor of selective and oral mTOR (IC50 of 7 nM).
Formula:
C23H21N7O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
411.46
Ref: TM-T12124
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
NVP-BAG956
CAS:853910-02-8
NVP-BAG956 is an ATP-competitive PI3K inhibitor (IC50s: 34/56/112/444 nM for PI3Kδ/PI3Kα/PI3Kγ/PI3Kβ).
Formula:
C28H21N5
Purity:
99.71%
Color and Shape:
Solid
Molecular weight:
427.5
Ref: TM-TQ0313
| 50mg | 700.00 € | ||
| 100mg | 1,273.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
PI3K/HDAC-IN-1
CAS:2361418-52-0
PI3K/HDAC-IN-1 is a potent PI3K and HDAC dual inhibitor(IC50s of 8.1 nM and 1.4 nM, …
Formula:
C22H25FN4O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
428.46
Ref: TM-T12455
| 25mg | 1,545.00 € | ||
| 50mg | 2,033.00 € | ||
| 100mg | 2,611.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
SDZ281-977
CAS:150779-71-8
SDZ 281-977 is a derivative of Lavendustin A which is the EGF receptor tyrosine kinase …
Formula:
C18H20O5
Purity:
99.64%
Color and Shape:
Solid
Molecular weight:
316.35
Ref: TM-T16866
| 1mg | 97.00 € | ||
| 5mg | 231.00 € | ||
| 10mg | 369.00 € | ||
| 25mg | 739.00 € | ||
| 50mg | 1,146.00 € | ||
| 1mL*10mM (DMSO) | 257.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
PI4KIII β inhibitor 3
CAS:1245319-54-3
PI4KIII beta inhibitor 3 is a novel and high effective inhibitor of PI4KIIIβ (IC50 of …
Formula:
C22H22N8OS
Purity:
98%
Color and Shape:
Solid
Molecular weight:
446.53
Ref: TM-T12467
| 1mg | 456.00 € | ||
| 500µg | 240.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Rezivertinib
CAS:1835667-12-3
Rezivertinib (BPI-7711) is an EGFR inhibitor with antitumor activity and can be used to study …
Formula:
C27H30N6O3
Purity:
99.43% - 99.43%
Color and Shape:
Liquid
Molecular weight:
486.57
Ref: TM-T36644
| 1mg | 169.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
EAI001
CAS:892772-75-7
EAI001 is a potent and selective mutant epidermal growth factor receptor (EGFR) variant inhibitor that …
Formula:
C19H15N3O2S
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
349.41
Ref: TM-T61191
| 5mg | 55.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 446.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
FT-1518
CAS:1313026-58-2
FT-1518 is an orally available, selective and potent mTORC1 and mTORC2 inhibitor with anticancer and …
Formula:
C20H26N8O
Purity:
98.80% - 98.80%
Color and Shape:
Solid
Molecular weight:
394.47
Ref: TM-T11328
| 1mg | 96.00 € | ||
| 25mg | 560.00 € | ||
| 50mg | 856.00 € | ||
| 100mg | 1,530.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Nuvenzepine
CAS:96487-37-5
Nuvenzepine is an antagonist of mAChR. It has the potential for gastrospasm treatment.
Formula:
C19H20N4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
336.39
Ref: TM-T16362
| 25mg | 1,410.00 € | ||
| 50mg | 1,875.00 € | ||
| 100mg | 2,317.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
AZD3458
CAS:2132961-46-5
AZD3458 is a potent and remarkably selective inhibitor of PI3Kγ (PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ …
Formula:
C20H23N3O4S2
Color and Shape:
Solid
Molecular weight:
433.54
Ref: TM-T12466
| 25mg | 900.00 € | ||
| 50mg | 1,180.00 € | ||
| 100mg | 2,050.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Falnidamol
CAS:196612-93-8
Falnidamol (BIBX 1382), an oral selective EGFR inhibitor, IC50 3 nM, weak on ErbB2 and …
Formula:
C18H19ClFN7
Purity:
96.46%
Color and Shape:
Solid
Molecular weight:
387.84
Ref: TM-TQ0271
| 2mg | 41.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 98.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 323.00 € | ||
| 100mg | 446.00 € | ||
| 200mg | 622.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
BKI-1369
CAS:1951431-22-3
BKI-1369 is a bumped kinase inhibitor. BKI-1369 increases hERG-inhibitory activity (IC50:1.52 μM).
Formula:
C23H27N7O
Color and Shape:
Solid
Molecular weight:
417.51
Ref: TM-T10556
| 5mg | 444.00 € | ||
| 25mg | 1,410.00 € | ||
| 50mg | 1,854.00 € | ||
| 100mg | 2,340.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
CAL-130 Hydrochloride
CAS:1431697-78-7
CAL-130 Hydrochloride is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).
Formula:
C23H23ClN8O
Color and Shape:
Solid
Molecular weight:
462.94
Ref: TM-T10660L
| 2mg | 122.00 € | ||
| 5mg | 234.00 € | ||
| 25mg | 708.00 € | ||
| 50mg | 929.00 € | ||
| 100mg | 1,395.00 € | ||
| 1mL*10mM (DMSO) | 271.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
