PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
Tyrphostin A25
CAS:118409-58-8
Tyrphostin A25 (Tyrphostin AG 82) is a specific EGFR tyrosine kinase inhibitor and GPR35 agonist …
Formula:
C10H6N2O3
Purity:
98.76%
Color and Shape:
Yellow Green Powder /Off-White Solid
Molecular weight:
202.17
Ref: TM-T21622
| 2mg | 38.00 € | ||
| 5mg | 55.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 117.00 € | ||
| 50mg | 173.00 € | ||
| 100mg | 246.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
GS-9901
CAS:1640247-87-5
GS-9901 is a selective, orally active and potent PI3Kδ inhibitor (IC50: 1 nM) for the …
Formula:
C22H17ClFN9O
Purity:
99.12% - 99.14%
Color and Shape:
Solid
Molecular weight:
477.88
Ref: TM-T15420
| 1mg | 90.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 322.00 € | ||
| 25mg | 691.00 € | ||
| 50mg | 915.00 € | ||
| 100mg | 1,270.00 € | ||
| 500mg | 2,559.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
bpV(phen)
CAS:42494-73-5
bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 …
Formula:
C12H8KN2O5V
Purity:
98%
Color and Shape:
Solid
Molecular weight:
350.24
Ref: TM-T10594
| 25mg | 1,406.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
XMD-17-51
CAS:1628614-50-5
XMD-17-51 is a potent and highly selective NUAK1 inhibitor.
Formula:
C21H24N8O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
404.47
Ref: TM-T22460
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
YM-53601 free base
CAS:182959-28-0
YM-53601 free base is an inhibitor of squalene synthetase which suppresses lipogenic biosynthesis and lipid …
Formula:
C21H21FN2O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
336.4
Ref: TM-T13371
| 25mg | 1,410.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,329.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
TGX-115
CAS:351071-62-0
TGX-115 inhibits PI 3-K p110β (IC50=0.13μM) & p110δ (IC50=0.63μM), treats various cardiovascular diseases.
Formula:
C20H20N2O3
Purity:
99.2%
Color and Shape:
Solid
Molecular weight:
336.38
Ref: TM-T24873
| 1mg | 326.00 € | ||
| 5mg | 769.00 € | ||
| 10mg | 1,049.00 € | ||
| 25mg | 1,486.00 € | ||
| 50mg | 1,846.00 € | ||
| 100mg | 2,331.00 € | ||
| 500mg | 4,547.00 € | ||
| 1mL*10mM (DMSO) | 645.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Tarlox-TKI
CAS:2135696-72-7
Tarlox-TKI (Kinase inhibitor-1) is a pan-ErbB inhibitor, the active ingredient of Tarloxotinib, which has antitumor …
Formula:
C19H18BrClN6O
Purity:
97.03%
Color and Shape:
Solid
Molecular weight:
461.74
Ref: TM-T11761
| 1mg | 142.00 € | ||
| 1mL*10mM (DMSO) | 253.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
APY0201
CAS:1232221-74-7
APY0201: potent, specific ATP-competitive PIKfyve inhibitor; IC50=5.2 nM; blocks PtdIns3P to PtdIns(3,5)P2 conversion.
Formula:
C23H23N7O
Purity:
98% - 99.21%
Color and Shape:
Solid
Molecular weight:
413.48
Ref: TM-T2061
| 1mg | 36.00 € | ||
| 2mg | 77.00 € | ||
| 5mg | 108.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 330.00 € | ||
| 50mg | 560.00 € | ||
| 100mg | 456.00 € | ||
| 200mg | 634.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
CHIR-99021 HCl
CAS:1797989-42-4
CHIR-99021 HCl is a selective GSK-3α/β inhibitor (IC50: 10/6.7 nM), 500x selective over other kinases, …
Formula:
C22H19Cl3N8
Purity:
98.07% - 98.44%
Color and Shape:
Solid
Molecular weight:
501.8
Ref: TM-T2310L
| 1mg | 36.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 77.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 241.00 € | ||
| 100mg | 466.00 € | ||
| 200mg | 676.00 € | ||
| 500mg | 1,026.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
BRD0209
CAS:1597439-87-6
BRD0209 is a highly selective and potent GSK3 inhibitor.
Formula:
C22H25N3O
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
347.45
Ref: TM-T26894
| 1mg | 60.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 195.00 € | ||
| 25mg | 350.00 € | ||
| 50mg | 499.00 € | ||
| 100mg | 680.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Aloisine B
CAS:496864-14-3
Aloisine B (AloisineB) inhibited cyclin-dependent kinase and glycogen synthase kinase with IC50 values of 0.85 …
Formula:
C15H14ClN3
Purity:
95.15%
Color and Shape:
Liquid
Molecular weight:
271.74
Ref: TM-T69188
| 1mg | 326.00 € | ||
| 5mg | 772.00 € | ||
| 10mg | 1,050.00 € | ||
| 25mg | 1,477.00 € | ||
| 50mg | 1,838.00 € | ||
| 100mg | 2,322.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
PI3K/mTOR Inhibitor-2
CAS:1848242-58-9
Potent PI3K/mTOR Inhibitor-2 targets PI3Kα/β/δ/γ & mTOR (IC50: 3.4, 34, 16,1, 4.7 nM); exhibits antitumor …
Formula:
C20H13ClF2N4O4S
Purity:
96.16%
Color and Shape:
Solid
Molecular weight:
478.86
Ref: TM-T12459
| 1mg | 56.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 218.00 € | ||
| 25mg | 364.00 € | ||
| 50mg | 520.00 € | ||
| 100mg | 703.00 € | ||
| 200mg | 903.00 € | ||
| 1mL*10mM (DMSO) | 147.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Larotinib
CAS:1438072-11-7
Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 …
Formula:
C24H26ClFN4O4
Purity:
98.45%
Color and Shape:
Liquid
Molecular weight:
488.94
Ref: TM-T73334
| 1mg | 80.00 € | ||
| 5mg | 172.00 € | ||
| 10mg | 253.00 € | ||
| 25mg | 430.00 € | ||
| 50mg | 615.00 € | ||
| 100mg | 861.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
CGP77675
CAS:234772-64-6
CGP77675 (ZINC1488120) is a potent and selective inhibitor of Src family kinase with IC50s of …
Formula:
C26H29N5O2
Purity:
98.23%
Color and Shape:
Solid
Molecular weight:
443.54
Ref: TM-T30855
| 1mg | 51.00 € | ||
| 2mg | 69.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 347.00 € | ||
| 50mg | 555.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
ML753286
CAS:1699720-89-2
ML753286 has high permeability and low to medium clearance in rodent and human liver S9 …
Formula:
C20H25N3O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
355.43
Ref: TM-T16113
| 25mg | 1,406.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,329.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
MBM-55S
CAS:2083624-07-9
MBM-55S, a Nek2 inhibitor with 1 nM IC50, induces cell cycle arrest and apoptosis, suppressing …
Formula:
C36H39FN6O10
Purity:
98.38% - 98.73%
Color and Shape:
Solid
Molecular weight:
734.73
Ref: TM-T11961
| 1mg | 183.00 € | ||
| 2mg | 273.00 € | ||
| 5mg | 422.00 € | ||
| 10mg | 618.00 € | ||
| 25mg | 926.00 € | ||
| 50mg | 1,304.00 € | ||
| 100mg | 1,763.00 € | ||
| 500mg | 3,508.00 € | ||
| 1mL*10mM (DMSO) | 622.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
M77976
CAS:394237-61-7
M77976 inhibits PDK4 with an IC50 of 648 μM, targeting obesity and diabetes research.
Formula:
C17H16N2O3
Purity:
99.80%
Color and Shape:
Solid
Molecular weight:
296.32
Ref: TM-T15944
| 1mg | 46.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 141.00 € | ||
| 25mg | 268.00 € | ||
| 50mg | 405.00 € | ||
| 100mg | 637.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
RTC-5
CAS:1423077-49-9
RTC-5 (TRC-382) is a phenothiazine compound that has been specifically enhanced for its potent anti-cancer …
Formula:
C24H22ClF3N2O3S
Purity:
98.14%
Color and Shape:
Solid
Molecular weight:
510.96
Ref: TM-T12777
| 5mg | 52.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 166.00 € | ||
| 50mg | 278.00 € | ||
| 100mg | 403.00 € | ||
| 500mg | 849.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
SKLB 1028
CAS:1350544-93-2
SKLB 1028, an oral EGFR/FLT3/Abl inhibitor, excels in AML and CML with Abl mutations.
Formula:
C24H29N9
Purity:
99.71% - 99.85%
Color and Shape:
Solid
Molecular weight:
443.55
Ref: TM-T34656
| 1mg | 56.00 € | ||
| 5mg | 120.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 378.00 € | ||
| 50mg | 560.00 € | ||
| 100mg | 802.00 € | ||
| 200mg | 634.00 € | ||
| 500mg | 1,616.00 € | ||
| 1mL*10mM (DMSO) | 144.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
PI3Kdelta inhibitor 1
CAS:2242109-74-4
PI3Kdelta inhibitor 1 is a potent, selective and orally available inhibitor of PI3Kδ with an …
Formula:
C27H38N6O5S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
558.69
Ref: TM-T12461
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
