PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
MP7
CAS:1001409-50-2
MP7 (PDK1 inhibitor) is a inhibitor of phosphoinositide-dependent kinase-1 (PDK1).
Formula:
C28H22F2N4O4
Purity:
99.45% - 99.84%
Color and Shape:
Solid
Molecular weight:
516.5
Ref: TM-T12398
| 1mg | 49.00 € | ||
| 5mg | 107.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
EGFR-IN-1 hydrochloride
CAS:2227455-78-7
EGFR-IN-1 HCl targets L858R/T790M EGFR mutants over wild-type; IC50: 4 nM in H1975, 28 nM …
Formula:
C28H31ClN6O4
Purity:
99.8%
Color and Shape:
Solid
Molecular weight:
551.04
Ref: TM-T11157L
| 1mg | 95.00 € | ||
| 5mg | 238.00 € | ||
| 10mg | 352.00 € | ||
| 25mg | 550.00 € | ||
| 50mg | 737.00 € | ||
| 100mg | 1,012.00 € | ||
| 500mg | 2,033.00 € | ||
| 1mL*10mM (DMSO) | 335.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
mTOR inhibitor-11
CAS:3033409-32-1
mTOR inhibitor-11 (Compound 9) is a brain-penetrant compound capable of inhibiting mTOR with an IC50 …
Formula:
C21H26N6O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
394.47
Ref: TM-T79211
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
EGFR-IN-1
CAS:1625677-63-5
EGFR-IN-1: an oral, irreversible EGFR inhibitor targeting L858R/T790M mutations with high selectivity, showing potent antitumor …
Formula:
C28H30N6O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
514.58
Ref: TM-T11157
| 25mg | 1,688.00 € | ||
| 50mg | 2,225.00 € | ||
| 100mg | 2,897.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
BEBT-109
CAS:2050906-40-4
BEBT-109 is a potent selective inhibitor of pan-mutant EGFR with enhanced pharmacokinetic properties, suitable for …
Formula:
C27H32N8O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
516.59
Ref: TM-T80643
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
NVP-QAV-572
CAS:957209-68-6
NVP-QAV-572 is a inhibitor of PI3K(IC50 of 10 nM).
Formula:
C17H19F2N7O3S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
471.5
Ref: TM-T12275
| 5mg | 232.00 € | ||
| 25mg | 711.00 € | ||
| 50mg | 928.00 € | ||
| 100mg | 1,411.00 € | ||
| 1mL*10mM (DMSO) | 264.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
T-00127_HEV1
CAS:900874-91-1
T-00127_HEV1 is an inhibitor of phosphatidylinositol 4-kinase III beta(PI4KIIIβ, IC50 = 60 nM).
Formula:
C22H29N5O3
Purity:
99.71%
Color and Shape:
Solid
Molecular weight:
411.5
Ref: TM-T16967
| 1mg | 56.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 371.00 € | ||
| 50mg | 553.00 € | ||
| 100mg | 791.00 € | ||
| 200mg | 634.00 € | ||
| 500mg | 1,613.00 € | ||
| 1mL*10mM (DMSO) | 243.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
PI3Kγ inhibitor 2
CAS:1315538-79-4
PI3Kγ inhibitor 2 is an orally bioavailable inhibitor of PI3Kγ(Ki of 4 nM).
Formula:
C20H18F3N5O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
433.38
Ref: TM-T12465
| 25mg | 1,688.00 € | ||
| 50mg | 2,226.00 € | ||
| 100mg | 2,899.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
MSC2360844
CAS:1305267-37-1
MSC2360844 is a potent, orally active and selective inhibitor of PI3Kδ(IC50 of 145 nM).
Formula:
C26H27FN4O5S
Purity:
100% - 99.32%
Color and Shape:
Solid
Molecular weight:
526.58
Ref: TM-T12115
| 1mg | 51.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 175.00 € | ||
| 25mg | 342.00 € | ||
| 50mg | 547.00 € | ||
| 100mg | 868.00 € | ||
| 200mg | 1,162.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
CAL-130 Racemate
CAS:474012-90-3
CAL-130 Racemate is the racemate of CAL-130. CAL-130 is a PI3Kδ and PI3Kγ inhibitor (IC50s: …
Formula:
C23H22N8O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
426.47
Ref: TM-T10660L2
| 25mg | 1,683.00 € | ||
| 50mg | 2,219.00 € | ||
| 100mg | 2,891.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
CC214-1
CAS:1021920-32-0
CC214-1 is an mTOR inhibitor that inhibits protein translation, induces autophagy, and is an in …
Formula:
C20H21N7O2
Purity:
97.87%
Color and Shape:
Solid
Molecular weight:
391.43
Ref: TM-T9314
| 1mg | 181.00 € | ||
| 5mg | 447.00 € | ||
| 10mg | 640.00 € | ||
| 25mg | 998.00 € | ||
| 50mg | 1,377.00 € | ||
| 100mg | 1,821.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
TCS 21311
CAS:1260181-14-3
TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective …
Formula:
C27H25F3N4O4
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
526.51
Ref: TM-T17019
| 1mg | 96.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
A 1070722
CAS:1384424-80-9
A 1070722: potent GSK-3 inhibitor, Ki = 0.6 nM for both α/β isoforms, crosses BBB, …
Formula:
C17H13F3N4O2
Purity:
99.78%
Color and Shape:
Solid
Molecular weight:
362.31
Ref: TM-T10202
| 5mg | 44.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 112.00 € | ||
| 50mg | 196.00 € | ||
| 100mg | 294.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
Duvelisib (R enantiomer)
CAS:1261590-48-0
Duvelisib R enantiomer (IPI-145 R enantiomer) is an enantiomer of Duvelisib with lower activity. Duvelisib …
Formula:
C22H17ClN6O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
416.86
Ref: TM-T11129
| 1mg | 40.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
Labuxtinib
CAS:1426449-01-5
Labutinib is a selective inhibitor of the c-kit tyrosine kinase [1].
Formula:
C20H16FN5O2
Purity:
99.77%
Color and Shape:
Liquid
Molecular weight:
377.37
Ref: TM-T79851
| 1mg | 138.00 € | ||
| 5mg | 333.00 € | ||
| 10mg | 533.00 € | ||
| 25mg | 1,059.00 € | ||
| 50mg | 1,523.00 € | ||
| 100mg | 2,046.00 € | ||
| 200mg | 2,763.00 € | ||
| 1mL*10mM (DMSO) | 369.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
GSK-3β inhibitor 8
CAS:1139875-74-3
GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII) is a potent and selective GSK-3β inhibitor with an …
Formula:
C20H20ClN5OS
Purity:
98%
Color and Shape:
Solid
Molecular weight:
413.92
Ref: TM-T35556
| 1mg | 108.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
AMPK-α1β1γ1 activator 1
CAS:1943510-86-8
AMPK-α1β1γ1 activator 1 (M1), an acyl glucuronide metabolite derived from an Indole-3-carboxylic Acid-based AMPK activator, …
Formula:
C25H24ClNO9
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
517.91
Ref: TM-T83125
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
PI3Kδ-IN-17
CAS:2768181-63-9
PI3Kδ-IN-17 (Compound S5) is a potent PI3K δ inhibitor, exhibiting an IC50 value of 2.82 …
Formula:
C23H24F3N7O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
487.48
Ref: TM-T81468
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
UCL-TRO-1938
CAS:2919575-27-0
UCL-TRO-1938 is a subtype-selective PI3Kα allosteric activator with cardioprotective and neuroregenerative effects.
Formula:
C27H32N6O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
456.58
Ref: TM-T78092
| 5mg | 116.00 € | ||
| 10mg | 179.00 € | ||
| 25mg | 376.00 € | ||
| 50mg | 602.00 € | ||
| 100mg | 963.00 € | ||
| 200mg | 1,330.00 € | ||
| 1mL*10mM (DMSO) | 120.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
PI3K/mTOR Inhibitor-14
CAS:2919684-77-6
PI3K/mTOR Inhibitor-14 (compound Y-2) serves as a dual inhibitor of PI3K and mTOR, exhibiting IC50 …
Formula:
C28H30N8O3S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
558.66
Ref: TM-T81470
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Feb 2025
