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PI3K/Akt/mTOR Signaling

PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.

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Subcategories of "PI3K/Akt/mTOR Signaling"

AMPK

ATM/ATR

DNA-PK

EGFR

MELK

PDK

PI3K

S6 Kinase

gsk-3

mTOR

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Products of "PI3K/Akt/mTOR Signaling"

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products per page. 694 products on this category.

BrandProduct dataPurityPrice rangeEstimated delivery
Targetmol logo
Laduviglusib trihydrochloride
REF: TM-T22657CAS: 1782235-14-6 		99.03%42.00 €~1,392.00 €Tue 21 Jan 25
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Epertinib
REF: TM-T11213LCAS: 908305-13-5 		98%423.00 €~2,336.00 €Tue 21 Jan 25
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CHMFL-PI3KD-317
REF: TM-T10804CAS: 2244992-76-3 		97.8%91.00 €~2,619.00 €Tue 21 Jan 25
Targetmol logo
K 00546
REF: TM-T21950CAS: 443798-47-8 		99.12%95.00 €~1,660.00 €Tue 21 Jan 25
Targetmol logo
MELK-8a hydrochloride
REF: TM-T11996CAS: 2096992-20-8 		99.87%42.00 €~1,207.00 €Tue 21 Jan 25
Targetmol logo
EGFR-IN-2
REF: TM-T11159CAS: 1643497-70-4 		98%907.00 €~2,337.00 €Tue 21 Jan 25
Targetmol logo
CAL-130
REF: TM-T10660CAS: 1431697-74-3 		98%904.00 €~2,329.00 €Tue 21 Jan 25
Targetmol logo
PI3K-IN-38
REF: TM-T61618CAS: 1382979-64-7 		99.74%181.00 €~1,698.00 €Tue 21 Jan 25
Targetmol logo
EGFR-IN-11
REF: TM-T11158CAS: 2463200-44-2 		99.37%To inquireTue 21 Jan 25
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ON 146040
REF: TM-T12310CAS: 1404231-34-0 		99.89%61.00 €~2,293.00 €Tue 21 Jan 25
Targetmol logo
JR-AB2-011
REF: TM-T11728CAS: 2411853-34-2 		98.87%94.00 €~1,234.00 €Tue 28 Jan 25
Targetmol logo
EGFR/ErbB-2 inhibitor-1
REF: TM-T79861CAS: 1135150-79-6 		97.55%182.00 €~3,652.00 €Tue 04 Feb 25
Targetmol logo
PI3K/VEGFR2-IN-1
REF: TM-T72713CAS: 2851067-08-6 		98%To inquireTue 04 Feb 25
Targetmol logo
(Rac)-BRD0705
REF: TM-T12664CAS: 1597440-03-3 		99.67%95.00 €~923.00 €Tue 04 Feb 25
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PIK-inhibitors
REF: TM-T3190CAS: 371934-59-7 		96.98%64.00 €~532.00 €Tue 04 Feb 25
Targetmol logo
5-Iodo-indirubin-3'-monoxime
REF: TM-T10172CAS: 331467-03-9 		- - -113.00 €~1,741.00 €Tue 04 Feb 25
Targetmol logo
Ampkinone
REF: TM-T10312CAS: 1233082-79-5 		98%522.00 €~1,072.00 €Tue 04 Feb 25
Targetmol logo
JGK-068S
REF: TM-T79124CAS: 2490431-16-6 		98%1,290.00 €~3,484.00 €Tue 04 Feb 25
Targetmol logo
mTOR inhibitor 9d
REF: TM-T67702CAS: 1144075-38-6 		98.90%326.00 €~4,551.00 €Tue 04 Feb 25
Targetmol logo
BRD5648
REF: TM-T10608CAS: 2056261-42-6 		99.37%68.00 €~645.00 €Tue 04 Feb 25
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Laduviglusib trihydrochloride
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Laduviglusib trihydrochloride

CAS:1782235-14-6
Laduviglusib trihydrochloride, a GSK-3α/β inhibitor (IC50: 10/6.7 nM), activates Wnt/β-catenin signaling and induces autophagy.
Formula:
C22H20Cl5N8
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
573.71

Ref: TM-T22657

1mg42.00 €
2mg56.00 €
5mg92.00 €
10mg134.00 €
25mg263.00 €
50mg498.00 €
100mg667.00 €
500mg1,392.00 €
1mL*10mM (DMSO)106.00 €
Estimated delivery in United States, on Tuesday 21 Jan 2025
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Epertinib
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Epertinib

CAS:908305-13-5
Epertinib is a reversible and selective tyrosine kinase inhibitor of EGFR, HER2, and HER4 (IC50s: …
Formula:
C30H27ClFN5O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
560.02

Ref: TM-T11213L

25mg1,262.00 €
50mg1,644.00 €
100mg2,336.00 €
Estimated delivery in United States, on Tuesday 21 Jan 2025
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CHMFL-PI3KD-317
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CHMFL-PI3KD-317

CAS:2244992-76-3
CHMFL-PI3KD-317: potent PI3Kδ inhibitor, IC50=6 nM, orally active, >10x selective vs. PI3K isoforms, anti-cancer.
Formula:
C21H24ClN5O3S2
Purity:
97.8%
Color and Shape:
Solid
Molecular weight:
494.03

Ref: TM-T10804

1mg91.00 €
5mg214.00 €
10mg326.00 €
25mg587.00 €
50mg881.00 €
100mg1,201.00 €
1mL*10mM (DMSO)233.00 €
Estimated delivery in United States, on Tuesday 21 Jan 2025
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K 00546
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K 00546

CAS:443798-47-8
K00546 inhibits CDK1/cyclin B (IC50: 0.6 nM), CDK2/cyclin A (IC50: 0.5 nM), CLK1 (IC50: 8.9 …
Formula:
C15H13F2N7O2S2
Purity:
99.12%
Color and Shape:
Solid
Molecular weight:
425.44

Ref: TM-T21950

1mg95.00 €
5mg242.00 €
25mg839.00 €
50mg1,076.00 €
100mg1,660.00 €
1mL*10mM (DMSO)292.00 €
Estimated delivery in United States, on Tuesday 21 Jan 2025
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MELK-8a hydrochloride
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MELK-8a hydrochloride

CAS:2096992-20-8
MELK-8a hydrochloride is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK, IC50 = …
Formula:
C25H33ClN6O
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
469.02

Ref: TM-T11996

1mg42.00 €
2mg55.00 €
5mg89.00 €
10mg126.00 €
25mg248.00 €
50mg396.00 €
100mg584.00 €
500mg1,207.00 €
1mL*10mM (DMSO)91.00 €
Estimated delivery in United States, on Tuesday 21 Jan 2025
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EGFR-IN-2
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EGFR-IN-2

CAS:1643497-70-4
EGFR-IN-2 is a non-covalent, mutation-selective and irreversible second-generation EGFR inhibitor.
Formula:
C26H33N9O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
551.66

Ref: TM-T11159

25mg1,410.00 €
50mg1,851.00 €
100mg2,337.00 €
Estimated delivery in United States, on Tuesday 21 Jan 2025
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CAL-130
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CAL-130

CAS:1431697-74-3
CAL-130 is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).
Formula:
C23H22N8O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
426.47

Ref: TM-T10660

25mg1,410.00 €
50mg1,845.00 €
100mg2,329.00 €
Estimated delivery in United States, on Tuesday 21 Jan 2025
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discount label
PI3K-IN-38
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PI3K-IN-38

CAS:1382979-64-7
PI3K-IN-38: oral PI3K inhibitor, IC50 of 0.541 µM, anticancer, anti-inflammatory, halts tumors in vivo.
Formula:
C20H24N6O2
Purity:
99.74%
Color and Shape:
Liquid
Molecular weight:
380.44

Ref: TM-T61618

1mg181.00 €
5mg400.00 €
10mg591.00 €
25mg916.00 €
50mg1,262.00 €
100mg1,698.00 €
Estimated delivery in United States, on Tuesday 21 Jan 2025
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discount label
EGFR-IN-11
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EGFR-IN-11

CAS:2463200-44-2
EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle …
Formula:
C29H35N9O2S
Purity:
99.37%
Color and Shape:
Solid
Molecular weight:
573.71

Ref: TM-T11158

1mg85.00 €
5mg182.00 €
10mg313.00 €
25mg496.00 €
50mg686.00 €
100mg911.00 €
500mgTo inquire
1mL*10mM (DMSO)236.00 €
Estimated delivery in United States, on Tuesday 21 Jan 2025
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discount label
ON 146040
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ON 146040

CAS:1404231-34-0
ON 146040 is an effective inhibitor of PI3K isoforms with IC50s of 14 and 20 …
Formula:
C24H23N7O3S
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
489.55

Ref: TM-T12310

1mg61.00 €
5mg140.00 €
10mg217.00 €
25mg354.00 €
50mg498.00 €
100mg666.00 €
200mg899.00 €
Estimated delivery in United States, on Tuesday 21 Jan 2025
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JR-AB2-011
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JR-AB2-011

CAS:2411853-34-2
JR-AB2-011: selective mTORC2 inhibitor, IC50 = 0.36μM, blocks Rictor-mTOR, Ki = 0.19μM, cytotoxic in glioblastoma.
Formula:
C17H14Cl2FN3OS
Purity:
98.87%
Color and Shape:
Solid
Molecular weight:
398.28

Ref: TM-T11728

1mg94.00 €
5mg199.00 €
10mg337.00 €
25mg616.00 €
50mg924.00 €
100mg1,234.00 €
1mL*10mM (DMSO)222.00 €
Estimated delivery in United States, on Tuesday 28 Jan 2025
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EGFR/ErbB-2 inhibitor-1
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EGFR/ErbB-2 inhibitor-1

CAS:1135150-79-6
EGFR/ErbB-2 inhibitor-1 is a selective ErbB2/HER2 inhibitor that effectively blocks ErbB2 and HER2 signaling.
Formula:
C23H15ClFN3OS2
Purity:
97.55%
Color and Shape:
Liquid
Molecular weight:
467.97

Ref: TM-T79861

1mg182.00 €
5mg449.00 €
10mg643.00 €
25mg1,004.00 €
50mg1,385.00 €
100mg1,831.00 €
500mg3,652.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
discount label
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PI3K/VEGFR2-IN-1

CAS:2851067-08-6
PI3K/VEGFR2-IN-1 is a potent dual inhibitor targeting both PI3K and VEGFR2 with IC50 values of …
Formula:
C17H14ClN3OS
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
343.83

Ref: TM-T72713

5mgTo inquire
50mgTo inquire
Estimated delivery in United States, on Tuesday 4 Feb 2025
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(Rac)-BRD0705
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(Rac)-BRD0705

CAS:1597440-03-3
(Rac)-BRD0705 is a less active racemate of BRD0705. BRD0705 is an effective and selective inhibitor …
Formula:
C20H23N3O
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
321.42

Ref: TM-T12664

1mg95.00 €
5mg208.00 €
10mg311.00 €
25mg501.00 €
50mg682.00 €
100mg923.00 €
1mL*10mM (DMSO)154.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
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PIK-inhibitors
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PIK-inhibitors

CAS:371934-59-7
PIK-inhibitors (MDK34597) is a pan PI3K inhibitors, an analog of PI-103.
Formula:
C19H17N5O2
Purity:
96.98%
Color and Shape:
Solid
Molecular weight:
347.37

Ref: TM-T3190

1mg64.00 €
5mg131.00 €
10mg229.00 €
25mg413.00 €
50mg532.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
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5-Iodo-indirubin-3'-monoxime
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5-Iodo-indirubin-3'-monoxime

CAS:331467-03-9
5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding …
Formula:
C16H10IN3O2
Color and Shape:
Solid
Molecular weight:
403.17

Ref: TM-T10172

5mg278.00 €
25mg916.00 €
50mg1,273.00 €
100mg1,741.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
discount label
Ampkinone
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Ampkinone

CAS:1233082-79-5
Ampkinone is an indirect AMPK activator.
Formula:
C31H23NO6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
505.52

Ref: TM-T10312

5mg522.00 €
10mg911.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
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discount label
JGK-068S
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JGK-068S

CAS:2490431-16-6
Compound I (JGK-068S) is a potent inhibitor of the epidermal growth factor receptor (EGFR) [1].
Formula:
C22H23BrFN5O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
488.35

Ref: TM-T79124

5mg1,290.00 €
50mg2,618.00 €
100mg3,484.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
discount label
mTOR inhibitor 9d
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mTOR inhibitor 9d

CAS:1144075-38-6
mTOR inhibitor 9d is a dual inhibitor of the protein kinases mTOR and PI3K with …
Formula:
C21H23N5O3S
Purity:
98.90%
Color and Shape:
Soild
Molecular weight:
425.5

Ref: TM-T67702

1mg326.00 €
5mg772.00 €
10mg1,050.00 €
25mg1,476.00 €
50mg1,839.00 €
100mg2,336.00 €
500mg4,551.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
discount label
BRD5648
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BRD5648

CAS:2056261-42-6
BRD5648 ((R)-BRD0705) is an inactive (R)-enantiomer of BRD0705.
Formula:
C20H23N3O
Purity:
99.37%
Color and Shape:
Solid
Molecular weight:
321.42

Ref: TM-T10608

1mg68.00 €
5mg140.00 €
10mg200.00 €
25mg334.00 €
50mg463.00 €
100mg645.00 €
1mL*10mM (DMSO)150.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
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