PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
Neolinine
CAS:112515-37-4
Neolinine(at 10uM) shows significant hERG K+ channel inhibition activity.
Formula:
C23H37NO6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
423.55
Ref: TM-TN4638
| 5mg | 623.00 € | ||
| 1mL*10mM (DMSO) | 633.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Duligotuzumab
CAS:1314238-96-4
Duligotuzumab (MEHD-7945A; RG 7597) is a humanized IgG-κ monoclonal antibody targeting Her3 (ErbB3) [1].
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T80604
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
mTOR inhibitor-14
mTOR Inhibitor-14 (compound 14c) is a potent inhibitor of mTOR with minimal inhibition of CYP2C8 …
Purity:
98%
Ref: TM-T81744
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
EGFR-IN-81
EGFR-IN-81 (Compound 10i), an EGFR inhibitor, demonstrates potent activity by inhibiting EGFR WT and the …
Formula:
C28H24F3N5O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
551.52
Ref: TM-T79327
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
EGFR/BRAFV600E-IN-3
EGFR/BRAFV600E-IN-3 is an inhibitor targeting EGFR, BRAFV600E, and EGFRT790M with IC50 values of 57 nM, …
Formula:
C25H18N4O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
422.44
Ref: TM-T78850
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
mTOR inhibitor 13
CAS:1144075-44-4
Urea derivative; selective mTOR blocker; IC50: 0.29nM (mTOR), 119nM (PI3Kα).
Formula:
C24H22N6O2S
Purity:
99.24%
Color and Shape:
Solid
Molecular weight:
458.54
Ref: TM-T9310
| 1mg | 182.00 € | ||
| 5mg | 442.00 € | ||
| 10mg | 602.00 € | ||
| 25mg | 913.00 € | ||
| 50mg | 1,227.00 € | ||
| 100mg | 1,614.00 € | ||
| 200mg | 2,185.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
mTOR inhibitor 9f
CAS:1144075-42-2
mTOR inhibitor 9f is a selective mTOR inhibitor with IC50 of 1.25nM and 82nM for …
Formula:
C25H23N5O2S
Purity:
98.39%
Color and Shape:
Soild
Molecular weight:
457.55
Ref: TM-T67701
| 1mg | 184.00 € | ||
| 5mg | 445.00 € | ||
| 10mg | 609.00 € | ||
| 25mg | 922.00 € | ||
| 50mg | 1,238.00 € | ||
| 100mg | 1,629.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
mTOR inhibitor 9e
CAS:1144075-40-0
mTOR inhibitor 9e is a selective mTOR inhibitor with IC50 of 0.68nM and 1359nM for …
Formula:
C22H23N5O2S
Purity:
98.80%
Color and Shape:
Soild
Molecular weight:
421.52
Ref: TM-T67704
| 1mg | 187.00 € | ||
| 5mg | 453.00 € | ||
| 10mg | 617.00 € | ||
| 25mg | 936.00 € | ||
| 50mg | 1,257.00 € | ||
| 100mg | 1,653.00 € | ||
| 200mg | 2,239.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
mTOR inhibitor 9c
CAS:1144075-36-4
mTOR inhibitor 9c is a selective mTOR inhibitor with IC50 of 0.7nM and 825nM for …
Formula:
C21H22FN5O2S
Purity:
98.73%
Color and Shape:
Soild
Molecular weight:
427.5
Ref: TM-T67706
| 1mg | 182.00 € | ||
| 5mg | 442.00 € | ||
| 10mg | 602.00 € | ||
| 25mg | 913.00 € | ||
| 50mg | 1,227.00 € | ||
| 100mg | 1,614.00 € | ||
| 200mg | 2,185.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
EGFR/CDK2-IN-4
EGFR/CDK2-IN-4 (compound 4c) is a dual inhibitor targeting EGFR and CDK-2, demonstrating IC50 values of …
Formula:
C24H16N6OS2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
468.55
Ref: TM-T79729
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CDK8-IN-12
CAS:2613307-67-6
CDK8-IN-12: selective CDK8 inhibitor (Ki 14 nM), oral anticancer, blocks GSK-3α/β, PCK-θ, halts MV4-11 cell …
Formula:
C21H20ClN3O2
Purity:
98.97% - 99.83%
Color and Shape:
Soild
Molecular weight:
381.86
Ref: TM-T72048
| 1mg | 79.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 240.00 € | ||
| 25mg | 411.00 € | ||
| 50mg | 598.00 € | ||
| 100mg | 837.00 € | ||
| 200mg | 1,144.00 € | ||
| 1mL*10mM (DMSO) | 185.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Sonolisib
CAS:502632-66-8
Sonolisib is an irreversible and pan-isoform inhibitor of PI3K (IC50=0.1 nM (p110α), 1.0 nM (p120γ), …
Formula:
C29H35NO8
Purity:
98%
Color and Shape:
Solid
Molecular weight:
525.59
Ref: TM-T16908
| 5mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
IHMT-PI3K-455
IHMT-PI3K-455 (Compound 15u) is a potent, selective PI3Kγ/δ dual inhibitor, demonstrating oral activity, with IC50 …
Formula:
C26H21F2N7O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
517.49
Ref: TM-T78836
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
N,N-Didesethyl Sunitinib Hydrochloride
CAS:873077-70-4
N,N-Didesethyl Sunitinib Hydrochloride is a potent AMPK inhibitor with IC50 of 393 nM and 141 …
Formula:
C18H19FN4O2
Purity:
97.1%
Color and Shape:
Soild
Molecular weight:
342.37
Ref: TM-T60128
| 1mg | 185.00 € | ||
| 2mg | 272.00 € | ||
| 5mg | 424.00 € | ||
| 10mg | 625.00 € | ||
| 25mg | 937.00 € | ||
| 50mg | 1,309.00 € | ||
| 100mg | 1,793.00 € | ||
| 500mg | 3,533.00 € | ||
| 1mL*10mM (DMSO) | 453.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Coprelotamab
CAS:2348469-84-9
Coprelotamab (GB-221) is an IgG-κ monoclonal antibody that targets EGFR2, frequently produced in CHO DG44 …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T80596
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Cisapride hydrate
CAS:260779-88-2
Cisapride acts directly as a selective agonist of serotonin 5-HT4 receptor with IC50 value of …
Formula:
C23H31ClFN3O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
483.97
Ref: TM-T22296
| 500mg | 552.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PI3Kα-IN-12
PI3Kα-IN-12 (compound 13), a potent and selective PI3Kα inhibitor (IC50: 1.2 nM), effectively suppresses HCT-116 …
Formula:
C28H36F2N10O5S3
Color and Shape:
Liquid
Molecular weight:
726.84
Ref: TM-T78804
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Petosemtamab
CAS:2213450-26-9
Petosemtamab (MCLA 158), a dual-action monoclonal antibody targets EGFR & LGR5, used in solid tumor …
Purity:
> 95% - > 95%
Color and Shape:
Liquid
Molecular weight:
145.97 kDa
Ref: TM-T76890
| 1mg | 332.00 € | ||
| 5mg | 862.00 € | ||
| 10mg | 1,392.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PI3Kα-IN-14
PI3Kα-IN-14 (compound F8), a potent PI3Kα inhibitor, exhibits an IC50 value of 0.14 nM and …
Purity:
98%
Ref: TM-T81469
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AMPK activator 13
AMPK Activator 13 is a potent activator of the AMPK pathway, effectively inhibiting mitotic clonal …
Purity:
98%
Ref: TM-T83127
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
